IT201700085439A1 - Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico - Google Patents

Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico

Info

Publication number
IT201700085439A1
IT201700085439A1 IT102017000085439A IT201700085439A IT201700085439A1 IT 201700085439 A1 IT201700085439 A1 IT 201700085439A1 IT 102017000085439 A IT102017000085439 A IT 102017000085439A IT 201700085439 A IT201700085439 A IT 201700085439A IT 201700085439 A1 IT201700085439 A1 IT 201700085439A1
Authority
IT
Italy
Prior art keywords
immobilization
analytical
biological samples
diagnostic purpose
diagnostic
Prior art date
Application number
IT102017000085439A
Other languages
English (en)
Inventor
Roberta Carbone
Gian Martino Franchi
Marni Marzia Luigia De
Original Assignee
Tethis S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tethis S P A filed Critical Tethis S P A
Priority to IT102017000085439A priority Critical patent/IT201700085439A1/it
Priority to LTEPPCT/IB2018/055456T priority patent/LT3658884T/lt
Priority to FIEP18753248.6T priority patent/FI3658884T3/fi
Priority to ES18753248T priority patent/ES2959261T3/es
Priority to EP18753248.6A priority patent/EP3658884B1/en
Priority to US16/631,253 priority patent/US20200209120A1/en
Priority to JP2020526710A priority patent/JP7289460B2/ja
Priority to CA3065045A priority patent/CA3065045A1/en
Priority to RU2020102076A priority patent/RU2020102076A/ru
Priority to PL18753248.6T priority patent/PL3658884T3/pl
Priority to CN201880049976.4A priority patent/CN110959110B/zh
Priority to PT187532486T priority patent/PT3658884T/pt
Priority to BR112020001726-4A priority patent/BR112020001726A2/pt
Priority to AU2018306481A priority patent/AU2018306481B2/en
Priority to DK18753248.6T priority patent/DK3658884T3/da
Priority to PCT/IB2018/055456 priority patent/WO2019021150A1/en
Publication of IT201700085439A1 publication Critical patent/IT201700085439A1/it

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Sustainable Development (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IT102017000085439A 2017-07-26 2017-07-26 Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico IT201700085439A1 (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT102017000085439A IT201700085439A1 (it) 2017-07-26 2017-07-26 Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico
LTEPPCT/IB2018/055456T LT3658884T (lt) 2017-07-26 2018-07-23 Biologinių mėginių imobilizavimo būdas, skirtas analitiniams ir diagnostiniams tikslams
FIEP18753248.6T FI3658884T3 (fi) 2017-07-26 2018-07-23 Menetelmä biologisten näytteiden immobilisoimiseksi analyyttisiä ja diagnostisia tarkoituksia
ES18753248T ES2959261T3 (es) 2017-07-26 2018-07-23 Método para inmovilizar muestras biológicas con fines analíticos y de diagnóstico
EP18753248.6A EP3658884B1 (en) 2017-07-26 2018-07-23 Method for immobilising biological samples for analytical and diagnostic purposes
US16/631,253 US20200209120A1 (en) 2017-07-26 2018-07-23 Method for immobilising biological samples for analytical and diagnostic purposes
JP2020526710A JP7289460B2 (ja) 2017-07-26 2018-07-23 分析および診断目的のために生体試料を固定化する方法
CA3065045A CA3065045A1 (en) 2017-07-26 2018-07-23 Method for immobilising biological samples for analytical and diagnostic purposes
RU2020102076A RU2020102076A (ru) 2017-07-26 2018-07-23 Способ иммобилизации биологических образцов для аналитических и диагностических целей
PL18753248.6T PL3658884T3 (pl) 2017-07-26 2018-07-23 Sposób unieruchamiania próbek biologicznych do celów analitycznych i diagnostycznych
CN201880049976.4A CN110959110B (zh) 2017-07-26 2018-07-23 用于固定生物样品以用于分析目的的方法
PT187532486T PT3658884T (pt) 2017-07-26 2018-07-23 Método para imobilizar amostras biológicas para fins analíticos e de diagnóstico
BR112020001726-4A BR112020001726A2 (pt) 2017-07-26 2018-07-23 método para imobilização de amostras biológicas para fins analíticos e de diagnóstico
AU2018306481A AU2018306481B2 (en) 2017-07-26 2018-07-23 Method for immobilising biological samples for analytical and diagnostic purposes
DK18753248.6T DK3658884T3 (da) 2017-07-26 2018-07-23 Fremgangsmåde til immobilisering af biologiske prøver til analytiske og diagnostiske formål
PCT/IB2018/055456 WO2019021150A1 (en) 2017-07-26 2018-07-23 METHOD FOR IMMOBILIZATION OF BIOLOGICAL SAMPLES FOR ANALYTICAL AND DIAGNOSTIC PURPOSES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000085439A IT201700085439A1 (it) 2017-07-26 2017-07-26 Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico

Publications (1)

Publication Number Publication Date
IT201700085439A1 true IT201700085439A1 (it) 2019-01-26

Family

ID=60294341

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000085439A IT201700085439A1 (it) 2017-07-26 2017-07-26 Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico

Country Status (16)

Country Link
US (1) US20200209120A1 (it)
EP (1) EP3658884B1 (it)
JP (1) JP7289460B2 (it)
CN (1) CN110959110B (it)
AU (1) AU2018306481B2 (it)
BR (1) BR112020001726A2 (it)
CA (1) CA3065045A1 (it)
DK (1) DK3658884T3 (it)
ES (1) ES2959261T3 (it)
FI (1) FI3658884T3 (it)
IT (1) IT201700085439A1 (it)
LT (1) LT3658884T (it)
PL (1) PL3658884T3 (it)
PT (1) PT3658884T (it)
RU (1) RU2020102076A (it)
WO (1) WO2019021150A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202100020600A1 (it) * 2021-07-30 2023-01-30 Tethis S P A Apparato e metodo di preparazione di un campione biologico per scopi analitici o diagnostici

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007009994A1 (en) * 2005-07-21 2007-01-25 Tethis S.R.L. Support having nanostructured titanium dioxide film and uses thereof
WO2012016136A2 (en) * 2010-07-30 2012-02-02 The General Hospital Corporation Microscale and nanoscale structures for manipulating particles
CN103667191A (zh) * 2012-09-07 2014-03-26 中国科学院化学研究所 利用分形结构的表面进行循环肿瘤细胞的特异性捕获的方法
US20150285808A1 (en) * 2011-09-30 2015-10-08 The Regents Of The University Of Michigan System for detecting rare cells
CN105950436A (zh) * 2016-04-20 2016-09-21 吉林大学 用于循环肿瘤细胞捕获的纳米结构微流控芯片及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0746100B2 (ja) * 1986-12-30 1995-05-17 素秀 高浜 細胞固定・保存液
WO2010083852A1 (en) 2009-01-26 2010-07-29 Tethis S.R.L. Functionalized microfluidic device for immunofluorescence
SG11201403041TA (en) * 2011-12-09 2014-08-28 Scripps Research Inst Apparatus, system and method for identifying circulating tumor cells
WO2014136885A1 (ja) 2013-03-08 2014-09-12 コニカミノルタ株式会社 組織染色用染色剤、組織染色用染色剤の製造方法および組織染色用染色剤を含む組織染色用キット

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007009994A1 (en) * 2005-07-21 2007-01-25 Tethis S.R.L. Support having nanostructured titanium dioxide film and uses thereof
WO2012016136A2 (en) * 2010-07-30 2012-02-02 The General Hospital Corporation Microscale and nanoscale structures for manipulating particles
US20150285808A1 (en) * 2011-09-30 2015-10-08 The Regents Of The University Of Michigan System for detecting rare cells
CN103667191A (zh) * 2012-09-07 2014-03-26 中国科学院化学研究所 利用分形结构的表面进行循环肿瘤细胞的特异性捕获的方法
CN105950436A (zh) * 2016-04-20 2016-09-21 吉林大学 用于循环肿瘤细胞捕获的纳米结构微流控芯片及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JUN OUYANG ET AL: "Morphology Controlled Poly(aminophenylboronic acid) Nanostructures as Smart Substrates for Enhanced Capture and Release of Circulating Tumor Cells", ADVANCED FUNCTIONAL MATERIALS, vol. 25, no. 38, 14 September 2015 (2015-09-14), DE, pages 6122 - 6130, XP055463843, ISSN: 1616-301X, DOI: 10.1002/adfm.201502420 *
XIANFENG YANG ET AL: "Hierarchically Nanostructured Rutile Arrays: Acid Vapor Oxidation Growth and Tunable Morphologies", ACS NANO, vol. 3, no. 5, 26 May 2009 (2009-05-26), US, pages 1212 - 1218, XP055464046, ISSN: 1936-0851, DOI: 10.1021/nn900084e *

Also Published As

Publication number Publication date
RU2020102076A3 (it) 2021-08-26
DK3658884T3 (da) 2023-10-23
CA3065045A1 (en) 2019-01-31
LT3658884T (lt) 2023-11-10
CN110959110B (zh) 2023-08-01
PL3658884T3 (pl) 2024-01-29
FI3658884T3 (fi) 2023-10-10
EP3658884B1 (en) 2023-09-20
ES2959261T3 (es) 2024-02-22
BR112020001726A2 (pt) 2020-07-21
US20200209120A1 (en) 2020-07-02
AU2018306481A1 (en) 2019-12-19
RU2020102076A (ru) 2021-08-26
JP7289460B2 (ja) 2023-06-12
CN110959110A (zh) 2020-04-03
AU2018306481B2 (en) 2024-02-29
EP3658884A1 (en) 2020-06-03
PT3658884T (pt) 2023-10-04
JP2020529866A (ja) 2020-10-15
WO2019021150A1 (en) 2019-01-31

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