SG11201403041TA - Apparatus, system and method for identifying circulating tumor cells - Google Patents

Apparatus, system and method for identifying circulating tumor cells

Info

Publication number
SG11201403041TA
SG11201403041TA SG11201403041TA SG11201403041TA SG11201403041TA SG 11201403041T A SG11201403041T A SG 11201403041TA SG 11201403041T A SG11201403041T A SG 11201403041TA SG 11201403041T A SG11201403041T A SG 11201403041TA SG 11201403041T A SG11201403041T A SG 11201403041TA
Authority
SG
Singapore
Prior art keywords
tumor cells
circulating tumor
identifying circulating
identifying
cells
Prior art date
Application number
SG11201403041TA
Inventor
Peter Kuhn
Anand Kolatkar
Gerd Marienfeld
Dena Marrinucci
Original Assignee
Scripps Research Inst
Gerd Marienfeld
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst, Gerd Marienfeld filed Critical Scripps Research Inst
Publication of SG11201403041TA publication Critical patent/SG11201403041TA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5088—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
SG11201403041TA 2011-12-09 2012-12-07 Apparatus, system and method for identifying circulating tumor cells SG11201403041TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161568793P 2011-12-09 2011-12-09
PCT/US2012/068586 WO2013086428A1 (en) 2011-12-09 2012-12-07 Apparatus, system and method for identifying circulating tumor cells

Publications (1)

Publication Number Publication Date
SG11201403041TA true SG11201403041TA (en) 2014-08-28

Family

ID=48574948

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201403041TA SG11201403041TA (en) 2011-12-09 2012-12-07 Apparatus, system and method for identifying circulating tumor cells

Country Status (14)

Country Link
US (1) US20140329917A1 (en)
EP (1) EP2788773A4 (en)
JP (1) JP2015505966A (en)
KR (1) KR20150008842A (en)
CN (1) CN104428677A (en)
AU (1) AU2012347526A1 (en)
BR (1) BR112014013956A2 (en)
CA (1) CA2858689A1 (en)
EA (1) EA201491140A1 (en)
HK (1) HK1201916A1 (en)
IL (1) IL233007A0 (en)
MX (1) MX2014006884A (en)
SG (1) SG11201403041TA (en)
WO (1) WO2013086428A1 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1816461T3 (en) 2002-10-16 2020-04-14 Streck Laboratories Inc Method and apparatus for collecting and securing cells for analysis
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
EP2398912B1 (en) 2009-02-18 2017-09-13 Streck Inc. Preservation of cell-free nucleic acids
EP2491395B1 (en) 2009-10-21 2015-09-16 The Scripps Research Institute Method of using non-rare cells to detect rare cells
EP2704740B1 (en) 2011-05-04 2016-10-05 Streck, Inc. Inactivated swine flu virus and methods of preparing it
US9396532B2 (en) * 2012-11-15 2016-07-19 Siemens Healthcare Diagnostics, Inc. Cell feature-based automatic circulating tumor cell detection
ES2938048T3 (en) 2013-07-24 2023-04-04 Streck Llc Compositions and methods for stabilizing circulating tumor cells
US9683938B2 (en) 2013-07-31 2017-06-20 The Regents Of The University Of California Fluorescent imaging using a flatbed scanner
CA2928779A1 (en) 2013-10-21 2015-04-30 The General Hospital Corporation Methods relating to circulating tumor cell clusters and the treatment of cancer
US10527624B2 (en) 2014-01-27 2020-01-07 Epic Sciences, Inc. Circulating tumor cell diagnostics for prostate cancer biomarkers
EA201691505A1 (en) * 2014-01-27 2016-12-30 Эпик Сайенсиз, Инк. DETECTION OF EXPRESSION OF PROSTATIC SPECIFIC MEMBRANE ANTIGEN (PSMA) ON CIRCULATING TUMOR CELLS (CTC)
ES2868077T3 (en) * 2014-01-30 2021-10-21 Epic Sciences Inc Diagnosis using circulating tumor cells for predictive biomarkers of resistance to selective androgen receptor (AR) therapies
EA201691682A1 (en) 2014-02-21 2017-02-28 Эпик Сайенсиз, Инк. METHODS FOR ANALYZING RARE CIRCULATING CELLS IN THE BLOOD
CN104062428B (en) * 2014-07-09 2016-08-17 郑勤 A kind of test kit detecting circulating tumor cell
CN107208151A (en) * 2014-12-10 2017-09-26 得克萨斯州大学系统董事会 Detected using the circulating tumor and tumor stem cell of genome specificity probe
US20160178630A1 (en) * 2014-12-18 2016-06-23 Creatv Microtech, Inc. Methods for predicting overall survival of cancer patients based on numbers of circulating tumor cells
JP6737185B2 (en) * 2015-01-29 2020-08-05 コニカミノルタ株式会社 Simultaneous detection of blood cells with interacting molecules
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
JP6815331B2 (en) * 2015-04-21 2021-01-20 ジェネンテック， インコーポレイテッド Compositions and Methods for Prostate Cancer Analysis
CA2984916A1 (en) * 2015-05-14 2016-11-17 The Board Of Trustees Of The University Of Illinois Method for monitoring efficacy of a cancer therapy using circulating tumor cells as a biomarker
JP6517933B2 (en) * 2015-06-24 2019-05-22 株式会社日立製作所 Inspection system, inspection apparatus, and inspection method
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
CN107873050A (en) * 2016-07-25 2018-04-03 株式会社奥普特尼克斯精密 Slide preparation of specimen device, the slide Slide processing of cell and the DNA or RNA extracting method of cell
WO2018022991A1 (en) 2016-07-29 2018-02-01 Streck, Inc. Suspension composition for hematology analysis control
WO2018116465A1 (en) * 2016-12-22 2018-06-28 日立化成株式会社 Method for detecting her2-positive cancer cells
US9738937B1 (en) 2017-03-31 2017-08-22 Cellmax, Ltd. Identifying candidate cells using image analysis
IT201700085439A1 (en) * 2017-07-26 2019-01-26 Tethis S P A METHOD OF IMMOBILIZATION OF BIOLOGICAL SAMPLES FOR ANALYTICAL AND DIAGNOSTIC PURPOSE
JP6485576B2 (en) * 2018-04-19 2019-03-20 日立化成株式会社 Standard cell solution
CN109887542A (en) * 2019-02-12 2019-06-14 嘉兴海云惠智医疗科技有限公司 A kind of tumour individuation genetic test intelligence solution read apparatus based on cloud computing
CN110146704A (en) * 2019-03-28 2019-08-20 苏州举健生物科技有限公司 A kind of medication and pathological examination data system based on circulating tumor cell
CN111323362A (en) * 2020-03-17 2020-06-23 宁波江丰生物信息技术有限公司 Circulating tumor cell detection system and method based on fluorescence section

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3830721A1 (en) * 1988-09-09 1990-03-22 Michael Dr Menton Slide for use in laboratories, especially in medical laboratories
CN2265982Y (en) * 1996-05-20 1997-10-29 中国农业大学 Flat-bottom square trough type cell micrographic operation glass slide
US8192994B2 (en) * 1998-02-10 2012-06-05 Angros Lee H Method of applying a biological specimen to an analytic plate
EP1101143A1 (en) * 1998-08-07 2001-05-23 Biogenex Laboratories Slides with reaction zones defined by hydrophobic barriers
CN2377532Y (en) * 1999-06-10 2000-05-10 中国人民解放军第二军医大学 Microfluorecyte counting plate
EP1337826A2 (en) * 2000-10-25 2003-08-27 Exiqon A/S Open substrate platforms suitable for analysis of biomolecules
US7943093B2 (en) * 2001-12-12 2011-05-17 Erie Scientific Company Cover slip
US20070009389A1 (en) * 2005-07-08 2007-01-11 Antti Seppo Slide deposition chamber
JP2009525468A (en) * 2006-01-30 2009-07-09 ザ・スクリプス・リサーチ・インステイチユート Method for detecting circulating tumor cells and method for diagnosing cancer in a mammalian subject
US8244021B2 (en) * 2006-12-20 2012-08-14 Ventana Medical Systems, Inc. Quantitative, multispectral image analysis of tissue specimens stained with quantum dots
WO2008151278A1 (en) * 2007-06-05 2008-12-11 Nanopoint, Inc. Cell tray systems and methods
CN201184866Y (en) * 2008-02-26 2009-01-21 强实贸易(上海)有限公司 Quantitative cell counting system apparatus
ES2661768T3 (en) * 2008-10-21 2018-04-03 Chemometec A/S Fluorescence imaging apparatus and procedure
CA2788245A1 (en) * 2010-01-27 2011-08-04 Duke University Biomarkers for circulating tumor cells

Also Published As

Publication number Publication date
BR112014013956A2 (en) 2017-06-13
CA2858689A1 (en) 2013-06-13
EA201491140A1 (en) 2014-11-28
HK1201916A1 (en) 2015-09-11
AU2012347526A1 (en) 2014-07-10
MX2014006884A (en) 2015-06-02
KR20150008842A (en) 2015-01-23
IL233007A0 (en) 2014-07-31
JP2015505966A (en) 2015-02-26
EP2788773A1 (en) 2014-10-15
WO2013086428A1 (en) 2013-06-13
US20140329917A1 (en) 2014-11-06
CN104428677A (en) 2015-03-18
EP2788773A4 (en) 2015-09-09

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