MX2014006884A - Aparato, sistema y metodo para identificar celulas tumorales circulantes. - Google Patents

Aparato, sistema y metodo para identificar celulas tumorales circulantes.

Info

Publication number
MX2014006884A
MX2014006884A MX2014006884A MX2014006884A MX2014006884A MX 2014006884 A MX2014006884 A MX 2014006884A MX 2014006884 A MX2014006884 A MX 2014006884A MX 2014006884 A MX2014006884 A MX 2014006884A MX 2014006884 A MX2014006884 A MX 2014006884A
Authority
MX
Mexico
Prior art keywords
well
cells
cell
sample
ctc
Prior art date
Application number
MX2014006884A
Other languages
English (en)
Spanish (es)
Inventor
Gerd Marienfeld
Peter Kuhn
Anand Kolatkar
Dena Marrinucci
Original Assignee
Gerd Marienfeld
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gerd Marienfeld filed Critical Gerd Marienfeld
Publication of MX2014006884A publication Critical patent/MX2014006884A/es

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5088—Rigid containers without fluid transport within confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/16—Apparatus for enzymology or microbiology containing, or adapted to contain, solid media
    • C12M1/18—Multiple fields or compartments
    • C12M1/20—Horizontal planar fields
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Multimedia (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Physiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
MX2014006884A 2011-12-09 2012-12-07 Aparato, sistema y metodo para identificar celulas tumorales circulantes. MX2014006884A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161568793P 2011-12-09 2011-12-09
PCT/US2012/068586 WO2013086428A1 (en) 2011-12-09 2012-12-07 Apparatus, system and method for identifying circulating tumor cells

Publications (1)

Publication Number Publication Date
MX2014006884A true MX2014006884A (es) 2015-06-02

Family

ID=48574948

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014006884A MX2014006884A (es) 2011-12-09 2012-12-07 Aparato, sistema y metodo para identificar celulas tumorales circulantes.

Country Status (14)

Country Link
US (1) US20140329917A1 (https=)
EP (1) EP2788773A4 (https=)
JP (1) JP2015505966A (https=)
KR (1) KR20150008842A (https=)
CN (1) CN104428677A (https=)
AU (1) AU2012347526A1 (https=)
BR (1) BR112014013956A2 (https=)
CA (1) CA2858689A1 (https=)
EA (1) EA201491140A1 (https=)
HK (1) HK1201916A1 (https=)
IL (1) IL233007A0 (https=)
MX (1) MX2014006884A (https=)
SG (1) SG11201403041TA (https=)
WO (1) WO2013086428A1 (https=)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2445204C (en) 2002-10-16 2014-08-12 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
WO2011050103A1 (en) 2009-10-21 2011-04-28 The Scripps Research Institute Method of using non-rare cells to detect rare cells
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
NO2398912T3 (https=) 2009-02-18 2018-02-10
US9956281B2 (en) 2011-05-04 2018-05-01 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
US9396532B2 (en) * 2012-11-15 2016-07-19 Siemens Healthcare Diagnostics, Inc. Cell feature-based automatic circulating tumor cell detection
US10091984B2 (en) 2013-07-24 2018-10-09 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US9683938B2 (en) 2013-07-31 2017-06-20 The Regents Of The University Of California Fluorescent imaging using a flatbed scanner
EP3683321B1 (en) * 2013-10-21 2021-12-08 The General Hospital Corporation Methods relating to circulating tumor cell clusters and the treatment of cancer
US20160011198A1 (en) * 2014-01-27 2016-01-14 Epic Sciences, Inc. Detection of prostate specific membrane antigen (psma) expression on circulating tumor cells (ctc)
US10527624B2 (en) 2014-01-27 2020-01-07 Epic Sciences, Inc. Circulating tumor cell diagnostics for prostate cancer biomarkers
US20150212089A1 (en) * 2014-01-30 2015-07-30 Epic Sciences, Inc. Circulating tumor cell diagnostics for biomarkers predictive of resistance to androgen receptor (ar) targeted therapies
EP3108246B1 (en) 2014-02-21 2019-10-09 Epic Sciences, Inc. Methods for analyzing rare circulating cells
CN104062428B (zh) * 2014-07-09 2016-08-17 郑勤 一种检测循环肿瘤细胞的试剂盒
CN113528663A (zh) * 2014-12-10 2021-10-22 得克萨斯州大学系统董事会 使用基因组特异性探针的循环肿瘤和肿瘤干细胞检测
US20160178630A1 (en) * 2014-12-18 2016-06-23 Creatv Microtech, Inc. Methods for predicting overall survival of cancer patients based on numbers of circulating tumor cells
US20180017568A1 (en) * 2015-01-29 2018-01-18 Konica Minolta, Inc. Method for simultaneously analyzing blood cells having interactive molecules
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
ES3007999T3 (en) * 2015-04-21 2025-03-21 Genentech Inc Compositions and methods for prostate cancer analysis
JP2018518689A (ja) * 2015-05-14 2018-07-12 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイＴｈｅ Ｂｏａｒｄ Ｏｆ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｉｌｌｉｎｏｉｓ バイオマーカーとして循環腫瘍細胞を使用するがん治療の有効性をモニタリングするための方法
WO2016207986A1 (ja) * 2015-06-24 2016-12-29 株式会社日立製作所 検査システム、検査装置、及び検査方法
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
US10641689B2 (en) * 2016-07-25 2020-05-05 Optnics Precision Co., Ltd. Method of preparing glass slide specimen of cells
WO2018022991A1 (en) 2016-07-29 2018-02-01 Streck, Inc. Suspension composition for hematology analysis control
WO2018116465A1 (ja) * 2016-12-22 2018-06-28 日立化成株式会社 Ｈｅｒ２陽性癌細胞の検出方法
US9738937B1 (en) 2017-03-31 2017-08-22 Cellmax, Ltd. Identifying candidate cells using image analysis
IT201700085439A1 (it) * 2017-07-26 2019-01-26 Tethis S P A Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico
CN115119829B (zh) 2017-10-19 2024-07-12 斯特雷克股份有限公司 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物
JP6485576B2 (ja) * 2018-04-19 2019-03-20 日立化成株式会社 標準細胞液
CN109887542A (zh) * 2019-02-12 2019-06-14 嘉兴海云惠智医疗科技有限公司 一种基于云计算的肿瘤个体化基因检测智能解读系统
CN110146704A (zh) * 2019-03-28 2019-08-20 苏州举健生物科技有限公司 一种基于循环肿瘤细胞的用药及病理检测数据系统
JP2021110664A (ja) * 2020-01-14 2021-08-02 学校法人杏林学園 癌被験体の予後を予測する方法
CN111323362A (zh) * 2020-03-17 2020-06-23 宁波江丰生物信息技术有限公司 一种基于荧光切片的循环肿瘤细胞检测系统及检测方法
CN114092934A (zh) * 2020-07-31 2022-02-25 骏实生物科技(上海)有限公司 循环肿瘤细胞的分类方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3830721A1 (de) * 1988-09-09 1990-03-22 Michael Dr Menton In labors, insbesondere in medizinischen labors, zu verwendender objekttraeger
CN2265982Y (zh) * 1996-05-20 1997-10-29 中国农业大学 平底方槽型细胞显微操作载片
US8192994B2 (en) * 1998-02-10 2012-06-05 Angros Lee H Method of applying a biological specimen to an analytic plate
EP1101143A1 (en) * 1998-08-07 2001-05-23 Biogenex Laboratories Slides with reaction zones defined by hydrophobic barriers
CN2377532Y (zh) * 1999-06-10 2000-05-10 中国人民解放军第二军医大学 微量荧光细胞计数板
AU2002249481A1 (en) * 2000-10-25 2002-08-12 Exiqon A/S Open substrate platforms suitable for analysis of biomolecules
US7943093B2 (en) * 2001-12-12 2011-05-17 Erie Scientific Company Cover slip
US20070009389A1 (en) * 2005-07-08 2007-01-11 Antti Seppo Slide deposition chamber
ES2420834T3 (es) * 2006-01-30 2013-08-27 The Scripps Research Institute Métodos de detección de células tumorales circulantes y métodos de diagnóstico del cáncer en un sujeto mamífero
US8244021B2 (en) * 2006-12-20 2012-08-14 Ventana Medical Systems, Inc. Quantitative, multispectral image analysis of tissue specimens stained with quantum dots
US20100184629A1 (en) * 2007-06-05 2010-07-22 Nanopoint, Inc. Cell tray systems and methods
CN201184866Y (zh) * 2008-02-26 2009-01-21 强实贸易(上海)有限公司 定量细胞计数系统装置
CA2741105C (en) * 2008-10-21 2019-01-15 Chemometec A/S Apparatus and methods for analyzing fluorescent particles
WO2011093927A1 (en) * 2010-01-27 2011-08-04 Duke University Biomarkers for circulating tumor cells

Also Published As

Publication number Publication date
EP2788773A4 (en) 2015-09-09
AU2012347526A1 (en) 2014-07-10
JP2015505966A (ja) 2015-02-26
HK1201916A1 (en) 2015-09-11
WO2013086428A1 (en) 2013-06-13
IL233007A0 (en) 2014-07-31
BR112014013956A8 (pt) 2017-06-13
KR20150008842A (ko) 2015-01-23
CA2858689A1 (en) 2013-06-13
SG11201403041TA (en) 2014-08-28
CN104428677A (zh) 2015-03-18
US20140329917A1 (en) 2014-11-06
EA201491140A1 (ru) 2014-11-28
EP2788773A1 (en) 2014-10-15
BR112014013956A2 (pt) 2017-06-13

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