|
GB1219606A
(en)
|
1968-07-15 |
1971-01-20 |
Rech S Et D Applic Scient Soge |
Quinuclidinol derivatives and preparation thereof
|
|
US3657744A
(en)
|
1970-05-08 |
1972-04-25 |
Univ Minnesota |
Method for fixing prosthetic implants in a living body
|
|
US4733665C2
(en)
|
1985-11-07 |
2002-01-29 |
Expandable Grafts Partnership |
Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
|
|
US5350395A
(en)
|
1986-04-15 |
1994-09-27 |
Yock Paul G |
Angioplasty apparatus facilitating rapid exchanges
|
|
US5061273A
(en)
|
1989-06-01 |
1991-10-29 |
Yock Paul G |
Angioplasty apparatus facilitating rapid exchanges
|
|
US4748982A
(en)
|
1987-01-06 |
1988-06-07 |
Advanced Cardiovascular Systems, Inc. |
Reinforced balloon dilatation catheter with slitted exchange sleeve and method
|
|
CA1322628C
(en)
|
1988-10-04 |
1993-10-05 |
Richard A. Schatz |
Expandable intraluminal graft
|
|
GB8916480D0
(en)
|
1989-07-19 |
1989-09-06 |
Glaxo Group Ltd |
Chemical process
|
|
US5674278A
(en)
|
1989-08-24 |
1997-10-07 |
Arterial Vascular Engineering, Inc. |
Endovascular support device
|
|
US5292331A
(en)
|
1989-08-24 |
1994-03-08 |
Applied Vascular Engineering, Inc. |
Endovascular support device
|
|
US6344053B1
(en)
|
1993-12-22 |
2002-02-05 |
Medtronic Ave, Inc. |
Endovascular support device and method
|
|
GB8923590D0
(en)
|
1989-10-19 |
1989-12-06 |
Pfizer Ltd |
Antimuscarinic bronchodilators
|
|
CS277070B6
(en)
|
1989-12-22 |
1992-11-18 |
Adamovske Strojirny Np |
Device for the control of printing pressures
|
|
PT100441A
(pt)
|
1991-05-02 |
1993-09-30 |
Smithkline Beecham Corp |
Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
|
|
JP3192424B2
(ja)
|
1992-04-02 |
2001-07-30 |
スミスクライン・ビーチャム・コーポレイション |
アレルギーまたは炎症疾患の治療用化合物
|
|
HU225869B1
(en)
|
1992-04-02 |
2007-11-28 |
Smithkline Beecham Corp |
Compounds with antiallergic and antiinflammatory activity and pharmaceutical compns. contg. them
|
|
EP0636026B1
(en)
|
1992-04-02 |
2001-12-05 |
Smithkline Beecham Corporation |
Compounds useful for treating inflammatory diseases and inhibiting production of tumor necrosis factor
|
|
GB9301000D0
(en)
|
1993-01-20 |
1993-03-10 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9414208D0
(en)
|
1994-07-14 |
1994-08-31 |
Glaxo Group Ltd |
Compounds
|
|
GB9414193D0
(en)
|
1994-07-14 |
1994-08-31 |
Glaxo Group Ltd |
Compounds
|
|
US5759787A
(en)
|
1996-08-26 |
1998-06-02 |
Tularik Inc. |
Kinase assay
|
|
GB9622386D0
(en)
|
1996-10-28 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
|
TW528755B
(en)
|
1996-12-24 |
2003-04-21 |
Glaxo Group Ltd |
2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
|
|
US6166037A
(en)
|
1997-08-28 |
2000-12-26 |
Merck & Co., Inc. |
Pyrrolidine and piperidine modulators of chemokine receptor activity
|
|
AU9281298A
(en)
|
1997-10-01 |
1999-04-23 |
Kyowa Hakko Kogyo Co. Ltd. |
Benzodioxole derivatives
|
|
GB9723590D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9723589D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9723566D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
YU44900A
(sh)
|
1998-01-31 |
2003-01-31 |
Glaxo Group Limited |
Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
|
|
PE20000270A1
(es)
|
1998-02-14 |
2000-05-20 |
Glaxo Group Ltd |
Derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol
|
|
GB9813540D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9813565D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
AU750462B2
(en)
|
1998-06-23 |
2002-07-18 |
Glaxo Group Limited |
2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
|
|
GB9813535D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
KR100563395B1
(ko)
|
1998-06-30 |
2006-03-23 |
다우 글로벌 테크놀로지스 인크. |
중합체 폴리올 및 이의 제조방법
|
|
AU5879299A
(en)
|
1998-10-16 |
2000-05-08 |
Monaghan, Sandra Marina |
Adenine derivatives
|
|
GB9913083D0
(en)
|
1999-06-04 |
1999-08-04 |
Novartis Ag |
Organic compounds
|
|
HK1039330B
(en)
|
1999-05-04 |
2005-12-09 |
Schering Corporation |
Piperidine derivatives useful as ccr5 antagonists
|
|
CA2371583C
(en)
|
1999-05-04 |
2005-09-13 |
Schering Corporation |
Piperazine derivatives useful as ccr5 antagonists
|
|
YU25500A
(sh)
|
1999-05-11 |
2003-08-29 |
Pfizer Products Inc. |
Postupak za sintezu analoga nukleozida
|
|
GB9913932D0
(en)
|
1999-06-15 |
1999-08-18 |
Pfizer Ltd |
Purine derivatives
|
|
US6322771B1
(en)
|
1999-06-18 |
2001-11-27 |
University Of Virginia Patent Foundation |
Induction of pharmacological stress with adenosine receptor agonists
|
|
ES2165768B1
(es)
|
1999-07-14 |
2003-04-01 |
Almirall Prodesfarma Sa |
Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
|
|
EP1212089B1
(en)
|
1999-08-21 |
2006-03-22 |
ALTANA Pharma AG |
Synergistic combination of roflumilast and salmeterol
|
|
CO5180581A1
(es)
|
1999-09-30 |
2002-07-30 |
Pfizer Prod Inc |
Compuestos para el tratamiento de la isquemia ciones farmaceuticas que los contienen para el tratamiento de la isquemia
|
|
EP1223952B1
(en)
|
1999-10-07 |
2008-04-16 |
Carlos Estuardo Aguilar-Cordova |
Methods for treatment of solid tumors and metastasis by gene therapy
|
|
GB9924361D0
(en)
|
1999-10-14 |
1999-12-15 |
Pfizer Ltd |
Purine derivatives
|
|
GB9924363D0
(en)
|
1999-10-14 |
1999-12-15 |
Pfizer Central Res |
Purine derivatives
|
|
GB0003960D0
(en)
|
2000-02-18 |
2000-04-12 |
Pfizer Ltd |
Purine derivatives
|
|
TWI227240B
(en)
|
2000-06-06 |
2005-02-01 |
Pfizer |
2-aminocarbonyl-9H-purine derivatives
|
|
GB0015727D0
(en)
|
2000-06-27 |
2000-08-16 |
Pfizer Ltd |
Purine derivatives
|
|
CZ294251B6
(cs)
|
2000-06-27 |
2004-11-10 |
Laboratorios S. A. L. V. A. T., S. A. |
Karbamáty a jejich použití pro výrobu farmaceutického prostředku
|
|
GB0015876D0
(en)
|
2000-06-28 |
2000-08-23 |
Novartis Ag |
Organic compounds
|
|
DE10038639A1
(de)
|
2000-07-28 |
2002-02-21 |
Schering Ag |
Nichtsteroidale Entzündungshemmer
|
|
WO2002012266A1
(en)
|
2000-08-05 |
2002-02-14 |
Glaxo Group Limited |
17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents
|
|
GB0022695D0
(en)
|
2000-09-15 |
2000-11-01 |
Pfizer Ltd |
Purine Derivatives
|
|
US20030165902A1
(en)
*
|
2000-09-29 |
2003-09-04 |
Bieglecki Karyn M. |
Haplotypes of the F2R gene
|
|
US6423546B1
(en)
*
|
2000-11-02 |
2002-07-23 |
Miller Brewing Company |
Monoclonal antibodies for assaying lipid transfer proteins
|
|
WO2002063046A1
(en)
*
|
2000-11-09 |
2002-08-15 |
Genaissance Pharmaceuticals, Inc. |
Haplotypes of the tacr2 gene
|
|
WO2002055534A2
(en)
*
|
2000-11-10 |
2002-07-18 |
Genaissance Pharmaceuticals |
Haplotypes of the f2rli gene
|
|
GB0028383D0
(en)
|
2000-11-21 |
2001-01-03 |
Novartis Ag |
Organic compounds
|
|
JP4445704B2
(ja)
|
2000-12-22 |
2010-04-07 |
アルミラル・ソシエダッド・アノニマ |
キヌクリジンカルバメート誘導体およびm3アンダゴニストとしてのそれらの使用
|
|
IL156558A0
(en)
|
2000-12-28 |
2004-01-04 |
Almirall Prodesfarma Ag |
Novel quinuclidine derivatives and medicinal compositions containing the same
|
|
EP1241176A1
(en)
|
2001-03-16 |
2002-09-18 |
Pfizer Products Inc. |
Purine derivatives for the treatment of ischemia
|
|
PT1383786E
(pt)
|
2001-04-30 |
2008-12-30 |
Glaxo Group Ltd |
Derivados anti-inflamatórios de éster 17.beta-carbotioato de androstano com um grupo éster ciclíco na posição 17.alfa
|
|
CZ20033126A3
(cs)
|
2001-05-25 |
2004-09-15 |
Pfizer Inc. |
Kombinace agonistu adenosin A2a receptoru a anticholinergického činidla pro ošetřování obstruktivních nemocí dýchacích cest
|
|
US20040248867A1
(en)
|
2001-06-12 |
2004-12-09 |
Keith Biggadike |
Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives
|
|
EP2319919B1
(en)
|
2001-06-21 |
2015-08-12 |
BASF Enzymes LLC |
Nitrilases
|
|
JP2005512974A
(ja)
|
2001-10-17 |
2005-05-12 |
ユ セ ベ ソシエテ アノニム |
キヌクリジン誘導体、その調製方法、及びm2及び/又はm3ムスカリン受容体阻害剤としてのその使用
|
|
GB0125259D0
(en)
|
2001-10-20 |
2001-12-12 |
Glaxo Group Ltd |
Novel compounds
|
|
AR037517A1
(es)
|
2001-11-05 |
2004-11-17 |
Novartis Ag |
Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
|
|
WO2003048181A1
(en)
|
2001-12-01 |
2003-06-12 |
Glaxo Group Limited |
17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
|
|
EP1461336B1
(en)
|
2001-12-20 |
2013-05-22 |
CHIESI FARMACEUTICI S.p.A. |
1-alkyl-1-azoniabicyclo (2.2.2) octane carbamate derivatives and their use as muscarinic receptor antagonists
|
|
WO2003072592A1
(en)
|
2002-01-15 |
2003-09-04 |
Glaxo Group Limited |
17.alpha-cycloalkyl/cycloylkenyl esters of alkyl-or haloalkyl-androst-4-en-3-on-11.beta.,17.alpha.-diol 17.beta.-carboxylates as anti-inflammatory agents
|
|
WO2003062259A2
(en)
|
2002-01-21 |
2003-07-31 |
Glaxo Group Limited |
Non-aromatic 17.alpha.-esters of androstane-17.beta.-carboxylate esters as anti-inflammatory agents
|
|
GB0202216D0
(en)
|
2002-01-31 |
2002-03-20 |
Glaxo Group Ltd |
Novel compounds
|
|
UA80120C2
(en)
|
2002-03-26 |
2007-08-27 |
Boehringer Ingelheim Pharma |
Glucocorticoid mimetics, pharmaceutical composition based thereon
|
|
CA2477764A1
(en)
|
2002-03-26 |
2003-10-09 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
AU2003234716A1
(en)
|
2002-04-10 |
2003-10-27 |
Joel M. Linden |
Use of a2a adenosine receptor agonists for the treatment of inflammatory diseases
|
|
ES2206021B1
(es)
|
2002-04-16 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de pirrolidinio.
|
|
ES2201907B1
(es)
|
2002-05-29 |
2005-06-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
|
|
DE10224888A1
(de)
|
2002-06-05 |
2003-12-24 |
Merck Patent Gmbh |
Pyridazinderivate
|
|
US7074806B2
(en)
|
2002-06-06 |
2006-07-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
DE10225574A1
(de)
|
2002-06-10 |
2003-12-18 |
Merck Patent Gmbh |
Aryloxime
|
|
DE10227269A1
(de)
|
2002-06-19 |
2004-01-08 |
Merck Patent Gmbh |
Thiazolderivate
|
|
EP1517895B1
(en)
|
2002-06-25 |
2007-03-14 |
Merck Frosst Canada Ltd. |
8-(biaryl) quinoline pde4 inhibitors
|
|
EP1519922A1
(en)
|
2002-07-02 |
2005-04-06 |
Merck Frosst Canada & Co. |
Di-aryl-substituted ethane pyridone pde4 inhibitors
|
|
ES2204295B1
(es)
|
2002-07-02 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de quinuclidina-amida.
|
|
SI1521733T1
(sl)
|
2002-07-08 |
2014-10-30 |
Pfizer Products Inc. |
Modulatorji glukokortikoidnega receptorja
|
|
PE20050130A1
(es)
|
2002-08-09 |
2005-03-29 |
Novartis Ag |
Compuestos organicos
|
|
WO2004018451A1
(en)
|
2002-08-10 |
2004-03-04 |
Altana Pharma Ag |
Pyridazinone-derivatives as pde4 inhibitors
|
|
CA2494613C
(en)
|
2002-08-10 |
2011-06-28 |
Altana Pharma Ag |
Pyrrolidinedione substituted piperidine-phthalazones as pde4 inhibitors
|
|
WO2004018450A1
(en)
|
2002-08-10 |
2004-03-04 |
Altana Pharma Ag |
Piperidine-n-oxide-derivatives
|
|
SE0202483D0
(sv)
|
2002-08-21 |
2002-08-21 |
Astrazeneca Ab |
Chemical compounds
|
|
JP2006501236A
(ja)
|
2002-08-23 |
2006-01-12 |
ランバクシー ラボラトリーズ リミテッド |
ムスカリン性レセプター拮抗薬としてのフルオロおよびスルホニルアミノ含有3,6−二置換アザビシクロ(3.1.0)ヘキサン誘導体
|
|
ES2281658T3
(es)
|
2002-08-29 |
2007-10-01 |
Nycomed Gmbh |
3-hidroxi-6-fenilfenantridinas como inhibidores de pde-4.
|
|
CA2495827C
(en)
|
2002-08-29 |
2012-05-08 |
Altana Pharma Ag |
2-hydroxy-6-phenylphenanthridines as pde-4 inhibitors
|
|
JP2006096662A
(ja)
|
2002-09-18 |
2006-04-13 |
Sumitomo Pharmaceut Co Ltd |
新規6−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
EP1541574A4
(en)
|
2002-09-18 |
2007-06-20 |
Ono Pharmaceutical Co |
TRIAZASPIRO DERIVATIVES 5.5 | UNDECANS AND DRUGS CONTAINING THEM AS AN ACTIVE INGREDIENT
|
|
JP2004107299A
(ja)
|
2002-09-20 |
2004-04-08 |
Japan Energy Corp |
新規1−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
DE10246374A1
(de)
|
2002-10-04 |
2004-04-15 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Betamimetika mit verlängerter Wirkungsdauer, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
|
EA010408B1
(ru)
|
2002-10-23 |
2008-08-29 |
Гленмарк Фармасьютикалс Лтд. |
Трициклические соединения для лечения воспалительных и аллергических нарушений, способы их приготовления и содержащие их фармацевтические составы
|
|
GB0225540D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Medicinal compounds
|
|
GB0225535D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Medicinal compounds
|
|
DE10253426B4
(de)
|
2002-11-15 |
2005-09-22 |
Elbion Ag |
Neue Hydroxyindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung
|
|
DE10253282A1
(de)
|
2002-11-15 |
2004-05-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
|
|
DE10253220A1
(de)
|
2002-11-15 |
2004-05-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Dihydroxy-Methyl-Phenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
|
US7727752B2
(en)
|
2003-07-29 |
2010-06-01 |
Life Technologies Corporation |
Kinase and phosphatase assays
|
|
CA2536140A1
(en)
|
2003-08-18 |
2005-02-24 |
Pfizer Products Inc. |
Dosing schedule for erbb2 anticancer agents
|
|
EP1771465B1
(en)
|
2004-07-23 |
2012-07-11 |
GE Healthcare UK Limited |
Cell cycle reporting cell line
|
|
EP2385053B1
(en)
|
2005-11-17 |
2013-10-02 |
OSI Pharmaceuticals, Inc. |
Intermediates for the preparation of fused bicyclic mTOR inhibitors
|
|
US7659274B2
(en)
|
2006-01-25 |
2010-02-09 |
Osi Pharmaceuticals, Inc. |
Unsaturated mTOR inhibitors
|
|
EP1996193A2
(en)
|
2006-03-13 |
2008-12-03 |
OSI Pharmaceuticals, Inc. |
Combined treatment with an egfr kinase inhibitor and an agent that sensitizes tumor cells to the effects of egfr kinase inhibitors
|
|
EP2178563A2
(en)
|
2007-07-06 |
2010-04-28 |
OSI Pharmaceuticals, Inc. |
Combination anti-cancer therapy comprising an inhibitor of both mtorc1 and mtorc2
|
|
US20090149511A1
(en)
|
2007-10-30 |
2009-06-11 |
Syndax Pharmaceuticals, Inc. |
Administration of an Inhibitor of HDAC and an mTOR Inhibitor
|
|
EP2318406B1
(en)
*
|
2008-07-17 |
2016-01-27 |
Critical Outcome Technologies, Inc. |
Thiosemicarbazone inhibitor compounds and cancer treatment methods
|
|
MX2011004585A
(es)
|
2008-10-31 |
2011-06-01 |
Novartis Ag |
Combinacion de un inhibidor de fosfatidilinositol-3-cinasa (p13k) y un inhibidor de mtor.
|
|
US8476431B2
(en)
*
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
|
CA2777128A1
(en)
*
|
2009-10-30 |
2011-05-05 |
Ariad Pharmaceuticals, Inc. |
Methods and compositions for treating cancer
|
|
CA2854926A1
(en)
*
|
2011-11-08 |
2013-05-16 |
Intellikine, Llc |
Treatment regimens using multiple pharmaceutical agents
|
|
CA2852127C
(en)
*
|
2011-11-11 |
2020-10-27 |
Duke University |
Combination drug therapy for the treatment of solid tumors
|
|
CA2856803A1
(en)
*
|
2011-11-23 |
2013-05-30 |
Intellikine, Llc |
Enhanced treatment regimens using mtor inhibitors
|