|
GB1219606A
(en)
|
1968-07-15 |
1971-01-20 |
Rech S Et D Applic Scient Soge |
Quinuclidinol derivatives and preparation thereof
|
|
US3657744A
(en)
|
1970-05-08 |
1972-04-25 |
Univ Minnesota |
Method for fixing prosthetic implants in a living body
|
|
US4733665C2
(en)
|
1985-11-07 |
2002-01-29 |
Expandable Grafts Partnership |
Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
|
|
US5061273A
(en)
|
1989-06-01 |
1991-10-29 |
Yock Paul G |
Angioplasty apparatus facilitating rapid exchanges
|
|
US5350395A
(en)
|
1986-04-15 |
1994-09-27 |
Yock Paul G |
Angioplasty apparatus facilitating rapid exchanges
|
|
US4748982A
(en)
|
1987-01-06 |
1988-06-07 |
Advanced Cardiovascular Systems, Inc. |
Reinforced balloon dilatation catheter with slitted exchange sleeve and method
|
|
CA1322628C
(en)
|
1988-10-04 |
1993-10-05 |
Richard A. Schatz |
Expandable intraluminal graft
|
|
GB8916480D0
(en)
|
1989-07-19 |
1989-09-06 |
Glaxo Group Ltd |
Chemical process
|
|
US6344053B1
(en)
|
1993-12-22 |
2002-02-05 |
Medtronic Ave, Inc. |
Endovascular support device and method
|
|
US5674278A
(en)
|
1989-08-24 |
1997-10-07 |
Arterial Vascular Engineering, Inc. |
Endovascular support device
|
|
US5292331A
(en)
|
1989-08-24 |
1994-03-08 |
Applied Vascular Engineering, Inc. |
Endovascular support device
|
|
GB8923590D0
(en)
|
1989-10-19 |
1989-12-06 |
Pfizer Ltd |
Antimuscarinic bronchodilators
|
|
CS277070B6
(en)
|
1989-12-22 |
1992-11-18 |
Adamovske Strojirny Np |
Device for the control of printing pressures
|
|
PT100441A
(pt)
|
1991-05-02 |
1993-09-30 |
Smithkline Beecham Corp |
Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
|
|
US5605923A
(en)
|
1992-04-02 |
1997-02-25 |
Smithkline Beecham Corporation |
Compounds useful for treating inflammatory diseases and inhibiting production of tumor necrosis factor
|
|
JP3192424B2
(ja)
|
1992-04-02 |
2001-07-30 |
スミスクライン・ビーチャム・コーポレイション |
アレルギーまたは炎症疾患の治療用化合物
|
|
HU225869B1
(en)
|
1992-04-02 |
2007-11-28 |
Smithkline Beecham Corp |
Compounds with antiallergic and antiinflammatory activity and pharmaceutical compns. contg. them
|
|
GB9301000D0
(en)
|
1993-01-20 |
1993-03-10 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9414208D0
(en)
|
1994-07-14 |
1994-08-31 |
Glaxo Group Ltd |
Compounds
|
|
GB9414193D0
(en)
|
1994-07-14 |
1994-08-31 |
Glaxo Group Ltd |
Compounds
|
|
US5759787A
(en)
|
1996-08-26 |
1998-06-02 |
Tularik Inc. |
Kinase assay
|
|
GB9622386D0
(en)
|
1996-10-28 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
|
TW528755B
(en)
|
1996-12-24 |
2003-04-21 |
Glaxo Group Ltd |
2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
|
|
US6166037A
(en)
|
1997-08-28 |
2000-12-26 |
Merck & Co., Inc. |
Pyrrolidine and piperidine modulators of chemokine receptor activity
|
|
AU9281298A
(en)
|
1997-10-01 |
1999-04-23 |
Kyowa Hakko Kogyo Co. Ltd. |
Benzodioxole derivatives
|
|
GB9723590D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9723566D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9723589D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
YU44900A
(sh)
|
1998-01-31 |
2003-01-31 |
Glaxo Group Limited |
Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
|
|
AR017457A1
(es)
|
1998-02-14 |
2001-09-05 |
Glaxo Group Ltd |
Compuestos derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol, procesos para su preparacion, composiciones que los contienen y su uso en terapia para el tratamiento de enfermedades inflamatorias.
|
|
GB9813565D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9813535D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
EA200001224A1
(ru)
|
1998-06-23 |
2001-08-27 |
Глаксо Груп Лимитед |
Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
|
|
GB9813540D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
BR9815931A
(pt)
|
1998-06-30 |
2001-02-20 |
Dow Chemical Co |
Polióis poliméricos, um processo para sua produção, e espuma de poliuretanoobtida
|
|
BR9914526A
(pt)
|
1998-10-16 |
2001-07-03 |
Pfizer |
Derivados de adenina
|
|
GB9913083D0
(en)
|
1999-06-04 |
1999-08-04 |
Novartis Ag |
Organic compounds
|
|
CZ301161B6
(cs)
|
1999-05-04 |
2009-11-18 |
Schering Corporation |
Piperidinopiperidylový derivát užitecný jako CCR5 antagonista, farmaceutický prostredek jej obsahující
|
|
TR200103214T2
(tr)
|
1999-05-04 |
2002-03-21 |
Schering Corporation |
CCR5 antagonistleri olarak yararlì piperazin trevleri.
|
|
YU25500A
(sh)
|
1999-05-11 |
2003-08-29 |
Pfizer Products Inc. |
Postupak za sintezu analoga nukleozida
|
|
GB9913932D0
(en)
|
1999-06-15 |
1999-08-18 |
Pfizer Ltd |
Purine derivatives
|
|
US6322771B1
(en)
|
1999-06-18 |
2001-11-27 |
University Of Virginia Patent Foundation |
Induction of pharmacological stress with adenosine receptor agonists
|
|
ES2165768B1
(es)
|
1999-07-14 |
2003-04-01 |
Almirall Prodesfarma Sa |
Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
|
|
CA2715683A1
(en)
|
1999-08-21 |
2001-03-01 |
Nycomed Gmbh |
Synergistic combination
|
|
CO5180581A1
(es)
|
1999-09-30 |
2002-07-30 |
Pfizer Prod Inc |
Compuestos para el tratamiento de la isquemia ciones farmaceuticas que los contienen para el tratamiento de la isquemia
|
|
AU7862600A
(en)
|
1999-10-07 |
2001-05-10 |
Carlos Estuardo Aguilar-Cordova |
Methods for treatment of solid tumors and metastasis by gene therapy
|
|
GB9924361D0
(en)
|
1999-10-14 |
1999-12-15 |
Pfizer Ltd |
Purine derivatives
|
|
GB9924363D0
(en)
|
1999-10-14 |
1999-12-15 |
Pfizer Central Res |
Purine derivatives
|
|
GB0003960D0
(en)
|
2000-02-18 |
2000-04-12 |
Pfizer Ltd |
Purine derivatives
|
|
TWI227240B
(en)
|
2000-06-06 |
2005-02-01 |
Pfizer |
2-aminocarbonyl-9H-purine derivatives
|
|
AU6610001A
(en)
|
2000-06-27 |
2002-01-08 |
S A L V A T Lab Sa |
Carbamates derived from arylalkylamines
|
|
GB0015727D0
(en)
|
2000-06-27 |
2000-08-16 |
Pfizer Ltd |
Purine derivatives
|
|
GB0015876D0
(en)
|
2000-06-28 |
2000-08-23 |
Novartis Ag |
Organic compounds
|
|
DE10038639A1
(de)
|
2000-07-28 |
2002-02-21 |
Schering Ag |
Nichtsteroidale Entzündungshemmer
|
|
EP2067784A3
(en)
|
2000-08-05 |
2012-08-22 |
Glaxo Group Limited |
17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivatives as anti-inflammatory agents
|
|
GB0022695D0
(en)
|
2000-09-15 |
2000-11-01 |
Pfizer Ltd |
Purine Derivatives
|
|
US20030165902A1
(en)
*
|
2000-09-29 |
2003-09-04 |
Bieglecki Karyn M. |
Haplotypes of the F2R gene
|
|
US6423546B1
(en)
*
|
2000-11-02 |
2002-07-23 |
Miller Brewing Company |
Monoclonal antibodies for assaying lipid transfer proteins
|
|
WO2002063046A1
(en)
*
|
2000-11-09 |
2002-08-15 |
Genaissance Pharmaceuticals, Inc. |
Haplotypes of the tacr2 gene
|
|
AU2002245073A1
(en)
*
|
2000-11-10 |
2002-07-24 |
Genaissance Pharmaceuticals, Inc. |
Haplotypes of the f2rli gene
|
|
GB0028383D0
(en)
|
2000-11-21 |
2001-01-03 |
Novartis Ag |
Organic compounds
|
|
HUP0303529A3
(en)
|
2000-12-22 |
2008-03-28 |
Almirall Ag |
New quinuclidine carbamate derivatives, process for their preparation and pharmaceutical compositions containing them and their use
|
|
CN1250545C
(zh)
|
2000-12-28 |
2006-04-12 |
阿尔米雷尔普罗迪斯制药有限公司 |
新的奎宁环衍生物类及含有这类衍生物的药物组合物
|
|
EP1241176A1
(en)
|
2001-03-16 |
2002-09-18 |
Pfizer Products Inc. |
Purine derivatives for the treatment of ischemia
|
|
WO2002088167A1
(en)
|
2001-04-30 |
2002-11-07 |
Glaxo Group Limited |
Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
|
|
PL366899A1
(en)
|
2001-05-25 |
2005-02-07 |
Pfizer Inc. |
An adenosine a2a receptor agonist and an anticholinergic agent in combination for treating obstructive airways diseases
|
|
ATE399174T1
(de)
|
2001-06-12 |
2008-07-15 |
Glaxo Group Ltd |
Neue anti inflammatorische 17.alpha.- heterozyklische ester von 17.beta.-carbothioat androstan derivativen
|
|
EP1578910A4
(en)
|
2001-06-21 |
2008-06-04 |
Verenium Corp |
NITRILASES
|
|
RU2004110717A
(ru)
|
2001-10-17 |
2005-10-20 |
Юсиби, С.А. (Be) |
Производные хинуклидина, способы их получения и их применение в качестве и нгибиторов м2- и/или м3- мускариновых рецепторов
|
|
GB0125259D0
(en)
|
2001-10-20 |
2001-12-12 |
Glaxo Group Ltd |
Novel compounds
|
|
AR037517A1
(es)
|
2001-11-05 |
2004-11-17 |
Novartis Ag |
Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
|
|
AU2002356759A1
(en)
|
2001-12-01 |
2003-06-17 |
Glaxo Group Limited |
17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
|
|
JP4505227B2
(ja)
|
2001-12-20 |
2010-07-21 |
キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ |
1−アルキル−1−アゾニアビシクロ[2.2.2]オクタンカルバメート誘導体およびムスカリンレセプターアンタゴニストとしてのそれらの使用
|
|
AU2003202044A1
(en)
|
2002-01-15 |
2003-09-09 |
Glaxo Group Limited |
17.alpha-cycloalkyl/cycloylkenyl esters of alkyl-or haloalkyl-androst-4-en-3-on-11.beta.,17.alpha.-diol 17.beta.-carboxylates as anti-inflammatory agents
|
|
AU2003201693A1
(en)
|
2002-01-21 |
2003-09-02 |
Glaxo Group Limited |
Non-aromatic 17.alpha.-esters of androstane-17.beta.-carboxylate esters as anti-inflammatory agents
|
|
GB0202216D0
(en)
|
2002-01-31 |
2002-03-20 |
Glaxo Group Ltd |
Novel compounds
|
|
AU2003230700A1
(en)
|
2002-03-26 |
2003-10-13 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
PL373043A1
(en)
|
2002-03-26 |
2005-08-08 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
EP1496911B1
(en)
|
2002-04-10 |
2007-12-19 |
University Of Virginia Patent Foundation |
Use of a combination comprising a2a adenosine receptor agonists and anti-pathogenic agents for the treatment of inflammatory diseases
|
|
ES2206021B1
(es)
|
2002-04-16 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de pirrolidinio.
|
|
ES2201907B1
(es)
|
2002-05-29 |
2005-06-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
|
|
DE10224888A1
(de)
|
2002-06-05 |
2003-12-24 |
Merck Patent Gmbh |
Pyridazinderivate
|
|
US7074806B2
(en)
|
2002-06-06 |
2006-07-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
DE10225574A1
(de)
|
2002-06-10 |
2003-12-18 |
Merck Patent Gmbh |
Aryloxime
|
|
DE10227269A1
(de)
|
2002-06-19 |
2004-01-08 |
Merck Patent Gmbh |
Thiazolderivate
|
|
ATE356808T1
(de)
|
2002-06-25 |
2007-04-15 |
Merck Frosst Canada Ltd |
8-(biaryl)chinolin-pde4-inhibitoren
|
|
WO2004005258A1
(en)
|
2002-07-02 |
2004-01-15 |
Merck Frosst Canada & Co. |
Di-aryl-substituted-ethane pyridone pde4 inhibitors
|
|
ES2204295B1
(es)
|
2002-07-02 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de quinuclidina-amida.
|
|
ES2518940T3
(es)
|
2002-07-08 |
2014-11-06 |
Pfizer Products Inc. |
Moduladores del receptor de glucocorticoides
|
|
PE20050130A1
(es)
|
2002-08-09 |
2005-03-29 |
Novartis Ag |
Compuestos organicos
|
|
JP2005538140A
(ja)
|
2002-08-10 |
2005-12-15 |
アルタナ ファルマ アクチエンゲゼルシャフト |
Pde4インヒビターとしてのピペリジン−ピリダゾン及びフタラゾン
|
|
CA2494650A1
(en)
|
2002-08-10 |
2004-03-04 |
Altana Pharma Ag |
Pyridazinone-derivatives as pde4 inhibitors
|
|
HRP20050197A2
(en)
|
2002-08-10 |
2006-06-30 |
Altana Pharma Ag |
Piperidine-n-oxide-derivatives
|
|
SE0202483D0
(sv)
|
2002-08-21 |
2002-08-21 |
Astrazeneca Ab |
Chemical compounds
|
|
JP2006501236A
(ja)
|
2002-08-23 |
2006-01-12 |
ランバクシー ラボラトリーズ リミテッド |
ムスカリン性レセプター拮抗薬としてのフルオロおよびスルホニルアミノ含有3,6−二置換アザビシクロ(3.1.0)ヘキサン誘導体
|
|
AU2003255493B8
(en)
|
2002-08-29 |
2009-03-26 |
Takeda Gmbh |
2-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors
|
|
US7423046B2
(en)
|
2002-08-29 |
2008-09-09 |
Nycomed Gmbh |
3-hydroxy-6-phenylphenanthridines as pde-4 inhibitors
|
|
JP2006096662A
(ja)
|
2002-09-18 |
2006-04-13 |
Sumitomo Pharmaceut Co Ltd |
新規6−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
KR20050057408A
(ko)
|
2002-09-18 |
2005-06-16 |
오노 야꾸힝 고교 가부시키가이샤 |
트리아자스피로[5.5]운데칸 유도체 및 이를 유효 성분으로하는 약제
|
|
JP2004107299A
(ja)
|
2002-09-20 |
2004-04-08 |
Japan Energy Corp |
新規1−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
DE10246374A1
(de)
|
2002-10-04 |
2004-04-15 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Betamimetika mit verlängerter Wirkungsdauer, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
|
WO2004037805A1
(en)
|
2002-10-23 |
2004-05-06 |
Glenmark Pharmaceuticals Ltd. |
Novel tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
|
|
GB0225535D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Medicinal compounds
|
|
GB0225540D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Medicinal compounds
|
|
DE10253220A1
(de)
|
2002-11-15 |
2004-05-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Dihydroxy-Methyl-Phenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE10253282A1
(de)
|
2002-11-15 |
2004-05-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
|
|
DE10253426B4
(de)
|
2002-11-15 |
2005-09-22 |
Elbion Ag |
Neue Hydroxyindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung
|
|
US7727752B2
(en)
|
2003-07-29 |
2010-06-01 |
Life Technologies Corporation |
Kinase and phosphatase assays
|
|
KR20080014144A
(ko)
*
|
2003-08-18 |
2008-02-13 |
화이자 프로덕츠 인크. |
erbB2 항암제에 대한 투약 스케쥴
|
|
EP1771466B1
(en)
|
2004-07-23 |
2010-05-26 |
GE Healthcare UK Limited |
Cell cycle phase markers
|
|
ES2436877T3
(es)
|
2005-11-17 |
2014-01-07 |
OSI Pharmaceuticals, LLC |
Intermedios para la preparación de inhibidores de mTOR bicíclicos condensados
|
|
US7659274B2
(en)
*
|
2006-01-25 |
2010-02-09 |
Osi Pharmaceuticals, Inc. |
Unsaturated mTOR inhibitors
|
|
WO2007106503A2
(en)
|
2006-03-13 |
2007-09-20 |
Osi Pharmaceuticals, Inc. |
Combined treatment with an egfr kinase inhibitor and an agent that sensitizes tumor cells to the effects of egfr kinase inhibitors
|
|
JP2010532756A
(ja)
*
|
2007-07-06 |
2010-10-14 |
オーエスアイ・ファーマスーティカルズ・インコーポレーテッド |
mTORC1及びmTORC2の両方の阻害剤を含む組み合わせ抗癌療法
|
|
US20090149511A1
(en)
|
2007-10-30 |
2009-06-11 |
Syndax Pharmaceuticals, Inc. |
Administration of an Inhibitor of HDAC and an mTOR Inhibitor
|
|
CA2730890C
(en)
*
|
2008-07-17 |
2018-05-15 |
Critical Outcome Technologies Inc. |
Thiosemicarbazone inhibitor compounds and cancer treatment methods
|
|
RU2538683C2
(ru)
*
|
2008-10-31 |
2015-01-10 |
Новартис Аг |
КОМБИНАЦИЯ ИНГИБИТОРА ФОСФАТИДИЛИНОЗИТОЛ-3-КИНАЗЫ (Р13К) И ИНГИБИТОРА mTOR
|
|
US8476282B2
(en)
*
|
2008-11-03 |
2013-07-02 |
Intellikine Llc |
Benzoxazole kinase inhibitors and methods of use
|
|
CA2777128A1
(en)
|
2009-10-30 |
2011-05-05 |
Ariad Pharmaceuticals, Inc. |
Methods and compositions for treating cancer
|
|
CN106924741A
(zh)
*
|
2011-11-08 |
2017-07-07 |
因特利凯有限责任公司 |
使用多种药剂的治疗方案
|
|
US9700619B2
(en)
*
|
2011-11-11 |
2017-07-11 |
Duke University |
Combination drug therapy for the treatment of solid tumors
|
|
US20130209543A1
(en)
*
|
2011-11-23 |
2013-08-15 |
Intellikine Llc |
Enhanced treatment regimens using mtor inhibitors
|