JP2014531205A5 - - Google Patents

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Publication number
JP2014531205A5
JP2014531205A5 JP2014530196A JP2014530196A JP2014531205A5 JP 2014531205 A5 JP2014531205 A5 JP 2014531205A5 JP 2014530196 A JP2014530196 A JP 2014530196A JP 2014530196 A JP2014530196 A JP 2014530196A JP 2014531205 A5 JP2014531205 A5 JP 2014531205A5
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JP
Japan
Prior art keywords
sequence
polypeptide
seq
glycoprotein
amino acid
Prior art date
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JP2014530196A
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English (en)
Japanese (ja)
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JP6076349B2 (ja
JP2014531205A (ja
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Priority claimed from GB201115841A external-priority patent/GB201115841D0/en
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Publication of JP2014531205A publication Critical patent/JP2014531205A/ja
Publication of JP2014531205A5 publication Critical patent/JP2014531205A5/ja
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Publication of JP6076349B2 publication Critical patent/JP6076349B2/ja
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JP2014530196A 2011-09-13 2012-09-12 ストレプトコッカス・ピオゲネス由来のエンドグリコシダーゼ及びその使用方法 Active JP6076349B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201115841A GB201115841D0 (en) 2011-09-13 2011-09-13 Protein and method
GB1115841.7 2011-09-13
PCT/EP2012/067841 WO2013037824A1 (en) 2011-09-13 2012-09-12 Endoglycosidase from streptococcus pyogenes and methods using it

Publications (3)

Publication Number Publication Date
JP2014531205A JP2014531205A (ja) 2014-11-27
JP2014531205A5 true JP2014531205A5 (enExample) 2015-10-29
JP6076349B2 JP6076349B2 (ja) 2017-02-08

Family

ID=44908522

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014530196A Active JP6076349B2 (ja) 2011-09-13 2012-09-12 ストレプトコッカス・ピオゲネス由来のエンドグリコシダーゼ及びその使用方法

Country Status (20)

Country Link
US (1) US9493752B2 (enExample)
EP (1) EP2756077B1 (enExample)
JP (1) JP6076349B2 (enExample)
KR (1) KR102001427B1 (enExample)
CN (1) CN103946377B (enExample)
AU (1) AU2012307461B2 (enExample)
BR (1) BR112014005816A2 (enExample)
CA (1) CA2848230C (enExample)
DK (1) DK2756077T3 (enExample)
EA (1) EA028490B8 (enExample)
ES (1) ES2627334T3 (enExample)
GB (2) GB201115841D0 (enExample)
IL (1) IL231410A0 (enExample)
IN (1) IN2014CN02163A (enExample)
MX (1) MX347727B (enExample)
PL (1) PL2756077T3 (enExample)
PT (1) PT2756077T (enExample)
SG (1) SG11201400505YA (enExample)
WO (1) WO2013037824A1 (enExample)
ZA (1) ZA201401840B (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595057B2 (en) * 2000-12-21 2009-09-29 Id Biomedical Corporation Streptococcus pyogenes antigens and corresponding DNA fragments
ES2659270T5 (en) 2012-10-23 2026-02-11 Synaffix Bv Modified antibody, antibody-conjugate and process for the preparation thereof
ES2759503T3 (es) 2013-05-02 2020-05-11 Glykos Finland Oy Conjugados de una glicoproteína o un glicano con una carga útil tóxica
CN105829543B (zh) 2013-10-14 2021-06-01 西纳福克斯股份有限公司 糖基改造的抗体、抗体-缀合物及其制备方法
CN105814213B (zh) 2013-10-14 2021-05-04 西纳福克斯股份有限公司 经修饰的糖蛋白、蛋白质-缀合物及其制备方法
US9987373B2 (en) 2013-10-14 2018-06-05 Synaffix B.V. Modified glycoprotein, protein-conjugate and process for the preparation thereof
EP3057618B1 (en) 2013-10-14 2022-12-14 SynAffix B.V. Glycoengineered antibody, antibody-conjugate and methods for their preparation
GB201318490D0 (en) * 2013-10-18 2013-12-04 Genovis Ab Method
EP3097079B1 (en) 2014-01-24 2021-05-12 SynAffix B.V. Process for the cycloaddition of a hetero(aryl) 1,3-dipole compound with a (hetero)cycloalkyne
EP3160513B1 (en) 2014-06-30 2020-02-12 Glykos Finland Oy Saccharide derivative of a toxic payload and antibody conjugates thereof
GB201413240D0 (en) * 2014-07-25 2014-09-10 Hansa Medical Ab Method
KR20170030648A (ko) 2014-08-04 2017-03-17 시나픽스 비.브이. 베타-(1,4)-n-아세틸갈락토오스아미닐트랜스퍼라아제, 또는 이의 돌연변이체를 이용한 당 단백질의 변형 방법
GB201502306D0 (en) * 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502305D0 (en) * 2015-02-12 2015-04-01 Hansa Medical Ab Protein
HUE038511T2 (hu) 2015-04-23 2018-10-29 Synaffix Bv (1,4)-N-acetil-galaktóz-aminil-transzferáz vagy (1,4)-N-acetil-galaktóz-aminil-transzferázból származó glikoziltranszferázt alkalmazó, glikoprotein módosítására szolgáló eljárás
EP3402815B1 (en) 2016-01-15 2023-12-06 University of Maryland, College Park Endo-s2 mutants as glycosynthases, method of making and use for glycoengineering of glycoproteins
AU2017214441B2 (en) * 2016-02-04 2021-08-19 Genovis Ab New Streptococcal proteases
JP6965350B2 (ja) * 2016-08-24 2021-11-10 チョ ファルマ インクCho Pharma Inc 糖タンパク質再構築のためのエンドグリコシダーゼ変異体及びその使用方法
PL3630968T3 (pl) 2017-05-26 2024-10-07 Genovis Ab Enzymy do analizy glikanów
US20210228738A1 (en) 2017-07-17 2021-07-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
WO2019243672A1 (en) 2018-06-19 2019-12-26 Glykos Biomedical Oy Conjugate
EP3813883A1 (en) 2018-06-29 2021-05-05 Glykos Biomedical Oy Conjugates
WO2021123506A1 (en) 2019-12-18 2021-06-24 Glykos Biomedical Oy Stabile conjugate
CN111044731B (zh) * 2019-12-19 2021-05-07 北京科技大学 脉冲温育免疫反应分离富集多肽药物中肽类杂质的方法
JP7846624B2 (ja) 2020-01-09 2026-04-15 メルサナ セラピューティクス インコーポレイテッド ペプチド含有リンカーとの部位特異的抗体-薬物コンジュゲート
GB202002072D0 (en) * 2020-02-14 2020-04-01 Hansa Biopharma AB immunoglobulin detection and associated therapies
EP4215208A4 (en) * 2020-09-21 2024-11-20 Shanghai Bao Pharmaceuticals Co., Ltd. PHARMACEUTICAL COMBINATION AND USE THEREOF
MX2023008000A (es) 2021-01-04 2023-07-13 Mersana Therapeutics Inc Conjugados de anticuerpo dirigido a b7-h4 y farmaco, y metodos de uso de los mismos.
EP4079848A1 (en) 2021-04-22 2022-10-26 Genovis Ab Immunoglobulin cleaving enzyme
CN118853710A (zh) * 2022-11-08 2024-10-29 上海泰昶生物技术有限公司 生产免疫球蛋白g降解酶的工程菌株和工艺
CN117165643B (zh) * 2023-08-17 2025-10-28 山东大学 一种糖苷内切酶在水解高甘露糖型n-糖蛋白中的应用
CN122003497A (zh) * 2023-11-10 2026-05-08 上海齐鲁制药研究中心有限公司 新型Endo S2突变体酶
TW202540414A (zh) * 2024-03-01 2025-10-16 大陸商上海齊魯製藥研究中心有限公司 新型Endo S2突變體酶
WO2025248500A1 (en) 2024-05-31 2025-12-04 Janssen Biotech, Inc. Antibody drug conjugates that target enpp3
GB202413764D0 (en) 2024-09-18 2024-10-30 Genovis Ab Immunoglobulin proteases and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130228D0 (en) 2001-12-18 2002-02-06 Hansa Medica Ab Protein
GB0624874D0 (en) * 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
JP5722627B2 (ja) * 2007-09-14 2015-05-27 ジェノビス エービー FCガンマ受容体−IgG複合体の解離、ならびにIgGの精製および検出のための方法およびキット
GB0821100D0 (en) 2008-11-18 2008-12-24 Hansa Medical Ab Antibodies
CN102511007B (zh) 2009-10-02 2015-04-15 罗切格利卡特公司 抗体中的a-岩藻糖基化检测

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