JP2019506866A5 - - Google Patents
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- Publication number
- JP2019506866A5 JP2019506866A5 JP2018540841A JP2018540841A JP2019506866A5 JP 2019506866 A5 JP2019506866 A5 JP 2019506866A5 JP 2018540841 A JP2018540841 A JP 2018540841A JP 2018540841 A JP2018540841 A JP 2018540841A JP 2019506866 A5 JP2019506866 A5 JP 2019506866A5
- Authority
- JP
- Japan
- Prior art keywords
- igg
- polypeptide
- protease activity
- cysteine protease
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 9
- 102000005927 Cysteine Proteases Human genes 0.000 claims 4
- 108010005843 Cysteine Proteases Proteins 0.000 claims 4
- 238000003776 cleavage reaction Methods 0.000 claims 4
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 230000007017 scission Effects 0.000 claims 4
- 150000001413 amino acids Chemical group 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 1
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 claims 1
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 238000001502 gel electrophoresis Methods 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022056522A JP2022115853A (ja) | 2016-02-04 | 2022-03-30 | 新しい連鎖球菌プロテアーゼ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1630021-2 | 2016-02-04 | ||
| SE1630021 | 2016-02-04 | ||
| PCT/EP2017/052463 WO2017134274A1 (en) | 2016-02-04 | 2017-02-03 | New streptococcal proteases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022056522A Division JP2022115853A (ja) | 2016-02-04 | 2022-03-30 | 新しい連鎖球菌プロテアーゼ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019506866A JP2019506866A (ja) | 2019-03-14 |
| JP2019506866A5 true JP2019506866A5 (enExample) | 2020-03-12 |
| JP7123801B2 JP7123801B2 (ja) | 2022-08-23 |
Family
ID=57995190
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540841A Active JP7123801B2 (ja) | 2016-02-04 | 2017-02-03 | 新しい連鎖球菌プロテアーゼ |
| JP2022056522A Withdrawn JP2022115853A (ja) | 2016-02-04 | 2022-03-30 | 新しい連鎖球菌プロテアーゼ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022056522A Withdrawn JP2022115853A (ja) | 2016-02-04 | 2022-03-30 | 新しい連鎖球菌プロテアーゼ |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12006530B2 (enExample) |
| EP (1) | EP3411389B1 (enExample) |
| JP (2) | JP7123801B2 (enExample) |
| KR (1) | KR102704583B1 (enExample) |
| CN (1) | CN109311951B (enExample) |
| AU (1) | AU2017214441B2 (enExample) |
| CA (1) | CA3013527C (enExample) |
| DK (1) | DK3411389T3 (enExample) |
| ES (1) | ES2877754T3 (enExample) |
| PL (1) | PL3411389T3 (enExample) |
| PT (1) | PT3411389T (enExample) |
| SG (1) | SG11201806639VA (enExample) |
| WO (1) | WO2017134274A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10267806B2 (en) | 2014-04-04 | 2019-04-23 | Mayo Foundation For Medical Education And Research | Isotyping immunoglobulins using accurate molecular mass |
| US11209439B2 (en) | 2015-09-24 | 2021-12-28 | Mayo Foundation For Medical Education And Research | Identification of immunoglobulin free light chains by mass spectrometry |
| WO2017134274A1 (en) | 2016-02-04 | 2017-08-10 | Ulrich Von Pawel-Rammingen | New streptococcal proteases |
| US10955420B2 (en) | 2016-09-07 | 2021-03-23 | Mayo Foundation For Medical Education And Research | Identification and monitoring of cleaved immunoglobulins by molecular mass |
| ES2986557T3 (es) | 2017-05-26 | 2024-11-11 | Genovis Ab | Enzimas para el análisis de glucanos |
| US20210228738A1 (en) | 2017-07-17 | 2021-07-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins |
| US11946937B2 (en) | 2017-09-13 | 2024-04-02 | Mayo Foundation For Medical Education And Research | Identification and monitoring of apoptosis inhibitor of macrophage |
| US12153052B2 (en) | 2017-09-13 | 2024-11-26 | Mayo Foundation For Medical Education And Research | Identification and monitoring of immunoglobulin J chains |
| CA3083977C (en) * | 2017-12-15 | 2025-05-27 | Intervet Int Bv | Streptococcus Vaccine |
| WO2021067598A1 (en) | 2019-10-04 | 2021-04-08 | Ultragenyx Pharmaceutical Inc. | Methods for improved therapeutic use of recombinant aav |
| GB202002072D0 (en) * | 2020-02-14 | 2020-04-01 | Hansa Biopharma AB | immunoglobulin detection and associated therapies |
| IL294781A (en) | 2020-02-14 | 2022-09-01 | Ultragenyx Pharmaceutical Inc | Gene therapy for treating cdkl5 deficiency disorder |
| WO2021254479A1 (zh) * | 2020-06-18 | 2021-12-23 | 上海宝济药业有限公司 | 一种免疫球蛋白降解酶IdeE的突变体 |
| US20230374542A1 (en) | 2020-10-07 | 2023-11-23 | Asklepios Biopharmaceutical, Inc. | Therapeutic adeno-associated virus delivery of fukutin related protein (fkrp) for treating dystroglycanopathy. disorders including limb girdle 21 (lgmd21) |
| WO2022221529A1 (en) | 2021-04-16 | 2022-10-20 | Asklepios Biopharmaceutical, Inc. | Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response |
| EP4079848A1 (en) | 2021-04-22 | 2022-10-26 | Genovis Ab | Immunoglobulin cleaving enzyme |
| WO2022266044A1 (en) * | 2021-06-15 | 2022-12-22 | The University Of North Carolina At Chapel Hill | Methods and compositions for depleting antibodies |
| US20250019721A1 (en) | 2021-08-11 | 2025-01-16 | Ultragenyx Pharmaceutical Inc. | Compositions and methods for treating a muscular dystrophy |
| JP2024540479A (ja) * | 2021-11-18 | 2024-10-31 | インターベット インターナショナル ベー． フェー． | ストレプトコッカス・スイスに対するワクチンの製造方法およびそのワクチン |
| AR131163A1 (es) * | 2022-11-25 | 2025-02-19 | Chugai Pharmaceutical Co Ltd | Métodos para producir proteínas |
| JPWO2025047641A1 (enExample) * | 2023-08-25 | 2025-03-06 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2824074A1 (fr) * | 2001-04-26 | 2002-10-31 | Pasteur Institut | Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques |
| GB0130228D0 (en) | 2001-12-18 | 2002-02-06 | Hansa Medica Ab | Protein |
| US20090104218A1 (en) | 2004-12-22 | 2009-04-23 | J. Craig Venter Institute | Group B Streptococcus |
| PL1901773T3 (pl) | 2005-06-09 | 2012-09-28 | Hansa Medical Ab | Zastosowanie proteinazy IDES (Z S. Pyogenes) do leczenia chorób autoimmunologicznych oraz odrzutów przeszczepu |
| DK2190984T3 (da) | 2007-09-14 | 2013-12-02 | Genovis Ab | Fremgangsmåder og kits til oprensning og påvisning af glycosyleret IgG |
| GB201115841D0 (en) * | 2011-09-13 | 2011-10-26 | Genovis Ab | Protein and method |
| GB201316744D0 (en) | 2013-09-20 | 2013-11-06 | Genovis Ab | Method |
| WO2017134274A1 (en) | 2016-02-04 | 2017-08-10 | Ulrich Von Pawel-Rammingen | New streptococcal proteases |
-
2017
- 2017-02-03 WO PCT/EP2017/052463 patent/WO2017134274A1/en not_active Ceased
- 2017-02-03 KR KR1020187025476A patent/KR102704583B1/ko active Active
- 2017-02-03 PL PL17703958T patent/PL3411389T3/pl unknown
- 2017-02-03 PT PT177039583T patent/PT3411389T/pt unknown
- 2017-02-03 CN CN201780022485.6A patent/CN109311951B/zh active Active
- 2017-02-03 CA CA3013527A patent/CA3013527C/en active Active
- 2017-02-03 SG SG11201806639VA patent/SG11201806639VA/en unknown
- 2017-02-03 ES ES17703958T patent/ES2877754T3/es active Active
- 2017-02-03 DK DK17703958.3T patent/DK3411389T3/da active
- 2017-02-03 US US16/075,059 patent/US12006530B2/en active Active
- 2017-02-03 AU AU2017214441A patent/AU2017214441B2/en active Active
- 2017-02-03 EP EP17703958.3A patent/EP3411389B1/en active Active
- 2017-02-03 JP JP2018540841A patent/JP7123801B2/ja active Active
-
2022
- 2022-03-30 JP JP2022056522A patent/JP2022115853A/ja not_active Withdrawn
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