JP7123801B2 - 新しい連鎖球菌プロテアーゼ - Google Patents

新しい連鎖球菌プロテアーゼ Download PDF

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JP7123801B2
JP7123801B2 JP2018540841A JP2018540841A JP7123801B2 JP 7123801 B2 JP7123801 B2 JP 7123801B2 JP 2018540841 A JP2018540841 A JP 2018540841A JP 2018540841 A JP2018540841 A JP 2018540841A JP 7123801 B2 JP7123801 B2 JP 7123801B2
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igg
seq
igde
amino acid
sequence
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JP2019506866A (ja
JP2019506866A5 (enExample
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パウエル－ラミンゲン，ウルリッチ ヴォン
スポエリー，クリスチャン
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ジェノビス エービー
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/641—Cysteine endopeptidases (3.4.22)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2018540841A 2016-02-04 2017-02-03 新しい連鎖球菌プロテアーゼ Active JP7123801B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022056522A JP2022115853A (ja) 2016-02-04 2022-03-30 新しい連鎖球菌プロテアーゼ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1630021-2 2016-02-04
SE1630021 2016-02-04
PCT/EP2017/052463 WO2017134274A1 (en) 2016-02-04 2017-02-03 New streptococcal proteases

Related Child Applications (1)

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JP2022056522A Division JP2022115853A (ja) 2016-02-04 2022-03-30 新しい連鎖球菌プロテアーゼ

Publications (3)

Publication Number Publication Date
JP2019506866A JP2019506866A (ja) 2019-03-14
JP2019506866A5 JP2019506866A5 (enExample) 2020-03-12
JP7123801B2 true JP7123801B2 (ja) 2022-08-23

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ID=57995190

Family Applications (2)

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JP2018540841A Active JP7123801B2 (ja) 2016-02-04 2017-02-03 新しい連鎖球菌プロテアーゼ
JP2022056522A Withdrawn JP2022115853A (ja) 2016-02-04 2022-03-30 新しい連鎖球菌プロテアーゼ

Family Applications After (1)

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JP2022056522A Withdrawn JP2022115853A (ja) 2016-02-04 2022-03-30 新しい連鎖球菌プロテアーゼ

Country Status (13)

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US (1) US12006530B2 (enExample)
EP (1) EP3411389B1 (enExample)
JP (2) JP7123801B2 (enExample)
KR (1) KR102704583B1 (enExample)
CN (1) CN109311951B (enExample)
AU (1) AU2017214441B2 (enExample)
CA (1) CA3013527C (enExample)
DK (1) DK3411389T3 (enExample)
ES (1) ES2877754T3 (enExample)
PL (1) PL3411389T3 (enExample)
PT (1) PT3411389T (enExample)
SG (1) SG11201806639VA (enExample)
WO (1) WO2017134274A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2944767C (en) 2014-04-04 2022-07-12 Mayo Foundation For Medical Education And Research Isotyping immunoglobulins using accurate molecular mass
US11209439B2 (en) 2015-09-24 2021-12-28 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
JP7123801B2 (ja) 2016-02-04 2022-08-23 ジェノビス エービー 新しい連鎖球菌プロテアーゼ
US10955420B2 (en) 2016-09-07 2021-03-23 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
CN111183221B (zh) 2017-05-26 2024-04-09 杰诺维斯公司 用于o-糖蛋白的蛋白酶和结合多肽
US20210228738A1 (en) 2017-07-17 2021-07-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
WO2019055632A1 (en) 2017-09-13 2019-03-21 Mayo Foundation For Medical Education And Research IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN CHAINS J
EP3681528B1 (en) 2017-09-13 2025-07-23 Mayo Foundation for Medical Education and Research Identification and monitoring of apoptosis inhibitor of macrophage
CN111447946A (zh) * 2017-12-15 2020-07-24 英特维特国际股份有限公司 用于针对猪链球菌进行保护的疫苗
WO2021067598A1 (en) 2019-10-04 2021-04-08 Ultragenyx Pharmaceutical Inc. Methods for improved therapeutic use of recombinant aav
BR112022015921A2 (pt) 2020-02-14 2022-10-04 Ultragenyx Pharmaceutical Inc Terapia gênica para tratar o transtorno de deficiência de cdkl5
GB202002072D0 (en) * 2020-02-14 2020-04-01 Hansa Biopharma AB immunoglobulin detection and associated therapies
JP2023532219A (ja) * 2020-06-18 2023-07-27 上海宝済薬業有限公司 免疫グロブリン分解酵素ＩｄｅＥの突然変異体
IL301955A (en) 2020-10-07 2023-06-01 Asklepios Biopharmaceutical Inc Therapeutic delivery of an adeno-related protein-related protein (FKRP) virus for the treatment of dystroglycanopathy disorders, including limb girdle 21
CA3216491A1 (en) 2021-04-16 2022-10-20 Asklepios Biopharmaceutical, Inc. Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response
EP4079848A1 (en) 2021-04-22 2022-10-26 Genovis Ab Immunoglobulin cleaving enzyme
US20240271115A1 (en) * 2021-06-15 2024-08-15 The University Of North Carolina At Chapel Hill Methods and compositions for depleting antibodies
WO2023019168A1 (en) 2021-08-11 2023-02-16 Ultragenyx Pharmaceutical Inc. Compositions and methods for treating a muscular dystrophy
CN118265540A (zh) * 2021-11-18 2024-06-28 英特维特国际股份有限公司 产生针对猪链球菌的疫苗的方法以及所述疫苗
TW202436348A (zh) * 2022-11-25 2024-09-16 日商中外製藥股份有限公司 蛋白質的製造方法
WO2025047641A1 (ja) * 2023-08-25 2025-03-06 積水メディカル株式会社 免疫学的測定方法、免疫学的測定用試薬、免疫学的測定用検体前処理液、及び免疫学的測定用試薬キット、非特異反応抑制剤
WO2025256978A1 (en) 2024-06-13 2025-12-18 Bayer Aktiengesellschaft Variants of igm and igg cleaving enzymes
WO2025256977A1 (en) 2024-06-13 2025-12-18 Bayer Aktiengesellschaft Novel igm and igg cleaving enzymes

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002092818A2 (fr) 2001-04-26 2002-11-21 Institut Pasteur Sequence du genome streptococcus agalactiae et ses utilisations
US20050119464A1 (en) 2001-12-18 2005-06-02 Ulrich Von Pawel-Rammingen Protein
JP2008542418A (ja) 2005-06-09 2008-11-27 ハンサ メディカル アクチボラゲット 自己免疫疾患及び移植片拒絶反応を治療するためのＩｄｅＳプロテイナーゼ（化膿連鎖球菌由来）の使用
WO2015040125A1 (en) 2013-09-20 2015-03-26 Genovis Ab A method for analysing a sample of immunoglobulin molecules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006069200A2 (en) 2004-12-22 2006-06-29 Novartis Vaccines And Diagnostics Inc. Group b streptococcus
EP2190984B1 (en) 2007-09-14 2013-09-04 Genovis Ab Methods and kits for purification and detection of glycosylated IgG
GB201115841D0 (en) * 2011-09-13 2011-10-26 Genovis Ab Protein and method
JP7123801B2 (ja) 2016-02-04 2022-08-23 ジェノビス エービー 新しい連鎖球菌プロテアーゼ

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002092818A2 (fr) 2001-04-26 2002-11-21 Institut Pasteur Sequence du genome streptococcus agalactiae et ses utilisations
US20050119464A1 (en) 2001-12-18 2005-06-02 Ulrich Von Pawel-Rammingen Protein
JP2008542418A (ja) 2005-06-09 2008-11-27 ハンサ メディカル アクチボラゲット 自己免疫疾患及び移植片拒絶反応を治療するためのＩｄｅＳプロテイナーゼ（化膿連鎖球菌由来）の使用
WO2015040125A1 (en) 2013-09-20 2015-03-26 Genovis Ab A method for analysing a sample of immunoglobulin molecules

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PLOS ONE，2016年10月17日，11(10), e0164809，pp.1-20

Also Published As

Publication number Publication date
EP3411389A1 (en) 2018-12-12
CA3013527A1 (en) 2017-08-10
KR20180124857A (ko) 2018-11-21
JP2019506866A (ja) 2019-03-14
AU2017214441B2 (en) 2021-08-19
SG11201806639VA (en) 2018-09-27
KR102704583B1 (ko) 2024-09-06
US20190345533A1 (en) 2019-11-14
PT3411389T (pt) 2021-06-28
EP3411389B1 (en) 2021-03-24
ES2877754T3 (es) 2021-11-17
JP2022115853A (ja) 2022-08-09
PL3411389T3 (pl) 2021-10-25
AU2017214441A1 (en) 2018-08-16
CA3013527C (en) 2023-09-05
DK3411389T3 (da) 2021-06-21
CN109311951B (zh) 2022-10-11
CN109311951A (zh) 2019-02-05
WO2017134274A1 (en) 2017-08-10
US12006530B2 (en) 2024-06-11

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