CA3013527C - New streptococcal proteases - Google Patents

New streptococcal proteases Download PDF

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Publication number
CA3013527C
CA3013527C CA3013527A CA3013527A CA3013527C CA 3013527 C CA3013527 C CA 3013527C CA 3013527 A CA3013527 A CA 3013527A CA 3013527 A CA3013527 A CA 3013527A CA 3013527 C CA3013527 C CA 3013527C
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Prior art keywords
igg
seq
igde
sequence
amino acid
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CA3013527A
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English (en)
French (fr)
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CA3013527A1 (en
Inventor
Ulrich Von Pawel-Rammingen
Christian SPOERRY
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Genovis AB
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Genovis AB
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/641Cysteine endopeptidases (3.4.22)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CA3013527A 2016-02-04 2017-02-03 New streptococcal proteases Active CA3013527C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1630021 2016-02-04
SE1630021-2 2016-02-04
PCT/EP2017/052463 WO2017134274A1 (en) 2016-02-04 2017-02-03 New streptococcal proteases

Publications (2)

Publication Number Publication Date
CA3013527A1 CA3013527A1 (en) 2017-08-10
CA3013527C true CA3013527C (en) 2023-09-05

Family

ID=57995190

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3013527A Active CA3013527C (en) 2016-02-04 2017-02-03 New streptococcal proteases

Country Status (13)

Country Link
US (1) US12006530B2 (enExample)
EP (1) EP3411389B1 (enExample)
JP (2) JP7123801B2 (enExample)
KR (1) KR102704583B1 (enExample)
CN (1) CN109311951B (enExample)
AU (1) AU2017214441B2 (enExample)
CA (1) CA3013527C (enExample)
DK (1) DK3411389T3 (enExample)
ES (1) ES2877754T3 (enExample)
PL (1) PL3411389T3 (enExample)
PT (1) PT3411389T (enExample)
SG (1) SG11201806639VA (enExample)
WO (1) WO2017134274A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015240454B2 (en) 2014-04-04 2019-08-22 Mayo Foundation For Medical Education And Research Isotyping immunoglobulins using accurate molecular mass
WO2017053932A1 (en) 2015-09-24 2017-03-30 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
WO2017134274A1 (en) 2016-02-04 2017-08-10 Ulrich Von Pawel-Rammingen New streptococcal proteases
WO2018049001A1 (en) 2016-09-07 2018-03-15 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
PT3630968T (pt) 2017-05-26 2024-07-30 Genovis Ab Enzimas para análise de glicanos
US20210228738A1 (en) 2017-07-17 2021-07-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
US12153052B2 (en) 2017-09-13 2024-11-26 Mayo Foundation For Medical Education And Research Identification and monitoring of immunoglobulin J chains
EP3681528B1 (en) 2017-09-13 2025-07-23 Mayo Foundation for Medical Education and Research Identification and monitoring of apoptosis inhibitor of macrophage
WO2019115743A1 (en) 2017-12-15 2019-06-20 Intervet International B.V. A vaccine for protection against streptococcus suis
JP2022550435A (ja) 2019-10-04 2022-12-01 ウルトラジェニックス ファーマシューティカル インコーポレイテッド 組換えaavの改善された治療的使用のための方法
GB202002072D0 (en) * 2020-02-14 2020-04-01 Hansa Biopharma AB immunoglobulin detection and associated therapies
IL294781A (en) 2020-02-14 2022-09-01 Ultragenyx Pharmaceutical Inc Gene therapy for treating cdkl5 deficiency disorder
US20230364207A1 (en) * 2020-06-18 2023-11-16 Shanghai Bao Pharmaceuticals Co., Ltd. Mutant of immunoglobulin degrading enzyme idee
EP4225382A4 (en) 2020-10-07 2025-04-23 AskBio Inc. ADMINISTRATION OF THERAPEUTIC ADENO-ASSOCIATED VIRUS FUKKUTIN-ASSOCIATED PROTEIN (FKRP) FOR THE TREATMENT OF DYSTROGLYCANOPATHY. DISORDERS INCLUDING LIMB GIRDLE 21
WO2022221529A1 (en) 2021-04-16 2022-10-20 Asklepios Biopharmaceutical, Inc. Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response
EP4079848A1 (en) 2021-04-22 2022-10-26 Genovis Ab Immunoglobulin cleaving enzyme
US20240271115A1 (en) * 2021-06-15 2024-08-15 The University Of North Carolina At Chapel Hill Methods and compositions for depleting antibodies
WO2023019168A1 (en) 2021-08-11 2023-02-16 Ultragenyx Pharmaceutical Inc. Compositions and methods for treating a muscular dystrophy
JP2024540479A (ja) * 2021-11-18 2024-10-31 インターベット インターナショナル ベー. フェー. ストレプトコッカス・スイスに対するワクチンの製造方法およびそのワクチン
TW202436348A (zh) * 2022-11-25 2024-09-16 日商中外製藥股份有限公司 蛋白質的製造方法
WO2025047641A1 (ja) * 2023-08-25 2025-03-06 積水メディカル株式会社 免疫学的測定方法、免疫学的測定用試薬、免疫学的測定用検体前処理液、及び免疫学的測定用試薬キット、非特異反応抑制剤
WO2025256978A1 (en) 2024-06-13 2025-12-18 Bayer Aktiengesellschaft Variants of igm and igg cleaving enzymes
WO2025256977A1 (en) 2024-06-13 2025-12-18 Bayer Aktiengesellschaft Novel igm and igg cleaving enzymes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2824074A1 (fr) * 2001-04-26 2002-10-31 Pasteur Institut Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques
GB0130228D0 (en) * 2001-12-18 2002-02-06 Hansa Medica Ab Protein
US20090104218A1 (en) 2004-12-22 2009-04-23 J. Craig Venter Institute Group B Streptococcus
PL1901773T3 (pl) 2005-06-09 2012-09-28 Hansa Medical Ab Zastosowanie proteinazy IDES (Z S. Pyogenes) do leczenia chorób autoimmunologicznych oraz odrzutów przeszczepu
EP2190984B1 (en) 2007-09-14 2013-09-04 Genovis Ab Methods and kits for purification and detection of glycosylated IgG
GB201115841D0 (en) * 2011-09-13 2011-10-26 Genovis Ab Protein and method
GB201316744D0 (en) * 2013-09-20 2013-11-06 Genovis Ab Method
WO2017134274A1 (en) 2016-02-04 2017-08-10 Ulrich Von Pawel-Rammingen New streptococcal proteases

Also Published As

Publication number Publication date
CN109311951B (zh) 2022-10-11
US20190345533A1 (en) 2019-11-14
PT3411389T (pt) 2021-06-28
CN109311951A (zh) 2019-02-05
JP2022115853A (ja) 2022-08-09
KR102704583B1 (ko) 2024-09-06
EP3411389A1 (en) 2018-12-12
EP3411389B1 (en) 2021-03-24
JP2019506866A (ja) 2019-03-14
WO2017134274A1 (en) 2017-08-10
CA3013527A1 (en) 2017-08-10
SG11201806639VA (en) 2018-09-27
JP7123801B2 (ja) 2022-08-23
US12006530B2 (en) 2024-06-11
AU2017214441B2 (en) 2021-08-19
KR20180124857A (ko) 2018-11-21
PL3411389T3 (pl) 2021-10-25
AU2017214441A1 (en) 2018-08-16
ES2877754T3 (es) 2021-11-17
DK3411389T3 (da) 2021-06-21

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