JP2014527969A5 - - Google Patents
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- Publication number
- JP2014527969A5 JP2014527969A5 JP2014530945A JP2014530945A JP2014527969A5 JP 2014527969 A5 JP2014527969 A5 JP 2014527969A5 JP 2014530945 A JP2014530945 A JP 2014530945A JP 2014530945 A JP2014530945 A JP 2014530945A JP 2014527969 A5 JP2014527969 A5 JP 2014527969A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pharmaceutically acceptable
- acceptable salt
- hydrogen
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 ****N(*)C(N(*)*)=NI Chemical compound ****N(*)C(N(*)*)=NI 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161536280P | 2011-09-19 | 2011-09-19 | |
| US61/536,280 | 2011-09-19 | ||
| PCT/US2012/055887 WO2013043580A2 (en) | 2011-09-19 | 2012-09-18 | Modified creatine compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017111480A Division JP2017160254A (ja) | 2011-09-19 | 2017-06-06 | 改変クレアチン化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014527969A JP2014527969A (ja) | 2014-10-23 |
| JP2014527969A5 true JP2014527969A5 (enExample) | 2015-11-12 |
Family
ID=46982949
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014530945A Ceased JP2014527969A (ja) | 2011-09-19 | 2012-09-18 | 改変クレアチン化合物 |
| JP2017111480A Pending JP2017160254A (ja) | 2011-09-19 | 2017-06-06 | 改変クレアチン化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017111480A Pending JP2017160254A (ja) | 2011-09-19 | 2017-06-06 | 改変クレアチン化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9434753B2 (enExample) |
| EP (1) | EP2758411A2 (enExample) |
| JP (2) | JP2014527969A (enExample) |
| CN (1) | CN103889993B (enExample) |
| AU (1) | AU2012312654B2 (enExample) |
| CA (1) | CA2849073A1 (enExample) |
| HK (1) | HK1200459A1 (enExample) |
| WO (1) | WO2013043580A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITTO20121098A1 (it) * | 2012-12-18 | 2014-06-19 | Univ Degli Studi Genova | Procedimento per sintetizzare derivati della creatina |
| RU2015143130A (ru) | 2013-03-15 | 2017-04-21 | Дженсиа Корпорейшен | Композиции и способы лечения состояний, поражающих эпидермис |
| US20160289175A1 (en) * | 2013-11-05 | 2016-10-06 | Ultragenyx Pharmaceutical Inc. | Creatine analogs and the use thereof |
| US9617230B2 (en) * | 2014-12-22 | 2017-04-11 | Farmington Pharma Development | Creatine prodrugs, compositions and methods of use thereof |
| TWI741979B (zh) | 2015-03-30 | 2021-10-11 | 美商法明頓製藥發展公司 | 磷酸肌酸類似物前藥、其組成物及用途 |
| US10883978B2 (en) * | 2017-01-31 | 2021-01-05 | Agilent Technologies, Inc. | Method and device for calibration of biological flux |
| WO2019026610A1 (ja) * | 2017-08-04 | 2019-02-07 | 学校法人 早稲田大学 | 微小空間の加温方法及び発熱体並びに微小空間の減温方法及び吸熱体 |
| IL274701B2 (en) | 2017-12-01 | 2024-07-01 | Ultragenyx Pharmaceutical Inc | Promote drugs, compositions and methods of their use |
| KR101920902B1 (ko) * | 2017-12-27 | 2018-11-21 | 전남대학교 산학협력단 | 심혈관 질환 조기진단 pet 조영용 화합물 및 그의 용도 |
| WO2021085906A1 (ko) * | 2019-10-30 | 2021-05-06 | 주식회사 퓨전바이오텍 | 미토콘드리아 표적 화합물 및 이를 포함하는 노화 관련 질환의 치료 또는 예방을 위한 조성물 |
| CN115417898B (zh) * | 2022-08-02 | 2024-03-26 | 浙江工业大学 | 一种三苯基鏻单体化合物及其制备方法与在制备核酸递送纳米载体中的应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988001213A1 (en) | 1986-08-18 | 1988-02-25 | Clinical Technologies Associates, Inc. | Delivery systems for pharmacological agents |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| AU4151996A (en) | 1994-11-08 | 1996-05-31 | Avicena Group, Inc. | Use of creatine or creatine analogs for the treatment of diseases of the nervous system |
| US20060128671A1 (en) | 1998-04-02 | 2006-06-15 | The General Hospital Corporation | Compositions containing a combination of a creatine compound and a second agent |
| EP1065931A4 (en) * | 1998-04-02 | 2006-10-11 | Avicena Group Inc | COMPOSITIONS CONTAINING CREATINE COMBINED WITH A SECOND AGENT |
| DE69913712T2 (de) | 1998-08-25 | 2004-10-07 | Uab Res Foundation Birmingham | Inhibitoren der bakteriellen nad synthetase |
| US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
| WO2005019232A1 (en) | 2003-08-22 | 2005-03-03 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
| MXPA01007760A (es) | 1999-02-01 | 2003-06-24 | Eisai Co Ltd | Compuesto adyuvante inmunologico. |
| US20040006242A1 (en) | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| US6242491B1 (en) | 1999-06-25 | 2001-06-05 | Rima Kaddurah-Daouk | Use of creatine or creatine compounds for skin preservation |
| US6355616B1 (en) * | 1999-06-25 | 2002-03-12 | Xoma (Us) Technology Ltd. | Derivative compounds derived from or based on bactericidal/permeability-increasing protein |
| US6534535B1 (en) | 1999-08-12 | 2003-03-18 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| HUP0303074A3 (en) | 2000-09-27 | 2007-08-28 | Ajinomoto Kk | Benzodiazepine derivatives and pharmaceutical compositions them |
| JP2005298343A (ja) | 2002-03-27 | 2005-10-27 | Ajinomoto Co Inc | ベンゾジアゼピン誘導体 |
| JP2003321499A (ja) | 2002-04-30 | 2003-11-11 | Internatl Reagents Corp | ミトコンドリアクレアチンキナーゼ抗体 |
| ES2436011T3 (es) * | 2003-02-04 | 2013-12-26 | Cornell Research Foundation, Inc. | Métodos para prevenir la transición de la permeabilidad mitocondrial |
| CN1839142B (zh) * | 2003-08-22 | 2010-06-16 | 澳新制药公司 | 用作靶向线粒体的抗氧化剂的线粒体醌衍生物 |
| WO2005056752A2 (en) | 2003-10-24 | 2005-06-23 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
| WO2006005759A2 (en) | 2004-07-13 | 2006-01-19 | Oridis Biomed Forschungs- Und Entwicklungs Gmbh | Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers |
| US7915230B2 (en) | 2005-05-17 | 2011-03-29 | Molecular Transfer, Inc. | Reagents for transfection of eukaryotic cells |
| US20070066572A1 (en) * | 2005-09-14 | 2007-03-22 | Kalyanaraman Balaraman | Neuroprotection by positively-charged nitroxides |
| FR2896162B1 (fr) | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
| JP5364574B2 (ja) | 2006-05-05 | 2013-12-11 | モレキュラー、トランスファー、インコーポレイテッド | 真核細胞のトランスフェクションのための新規試薬 |
| AU2007300782B2 (en) * | 2006-09-28 | 2013-08-29 | United Kingdom Research And Innovation | Triphenylphosphonium thionitrite nitric oxide donors |
| EP2197890A1 (en) * | 2007-09-07 | 2010-06-23 | Gencia Corporation | Mitochondrial compositions and uses thereof |
| ATE551342T1 (de) | 2008-02-22 | 2012-04-15 | Irm Llc | Heterocyclische verbindungen und zusammensetzungen als c-kit- und pdgfr- kinasehemmer |
| WO2009111846A1 (en) | 2008-03-14 | 2009-09-17 | Stephen John Ralph | Mitochondrially delivered anti-cancer compounds |
| WO2010126719A1 (en) * | 2009-04-27 | 2010-11-04 | Mcw Research Foundation, Inc. | Neuroprotective compounds and their use |
| WO2011011366A2 (en) * | 2009-07-20 | 2011-01-27 | Constellation Pharmaceuticals | Agents for stimulating activity of methyl modifying enzymes and methods of use thereof |
| US9212177B2 (en) | 2009-08-05 | 2015-12-15 | Versitech Limited | Antiviral compounds and methods of making and using thereof |
| US20130190244A1 (en) * | 2009-12-31 | 2013-07-25 | Stealth Peptides International, Inc. | Methods for performing a coronary artery bypass graft procedure |
| WO2011147199A1 (en) | 2010-05-28 | 2011-12-01 | Versitech Limited | Compounds and methods for treating viral infections |
-
2012
- 2012-09-18 HK HK15100837.0A patent/HK1200459A1/xx unknown
- 2012-09-18 AU AU2012312654A patent/AU2012312654B2/en not_active Ceased
- 2012-09-18 EP EP12769555.9A patent/EP2758411A2/en not_active Withdrawn
- 2012-09-18 WO PCT/US2012/055887 patent/WO2013043580A2/en not_active Ceased
- 2012-09-18 JP JP2014530945A patent/JP2014527969A/ja not_active Ceased
- 2012-09-18 CA CA2849073A patent/CA2849073A1/en not_active Abandoned
- 2012-09-18 CN CN201280052878.9A patent/CN103889993B/zh not_active Expired - Fee Related
- 2012-09-18 US US14/345,503 patent/US9434753B2/en not_active Expired - Fee Related
-
2017
- 2017-06-06 JP JP2017111480A patent/JP2017160254A/ja active Pending
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