JP2014527529A5 - - Google Patents
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- Publication number
- JP2014527529A5 JP2014527529A5 JP2014526090A JP2014526090A JP2014527529A5 JP 2014527529 A5 JP2014527529 A5 JP 2014527529A5 JP 2014526090 A JP2014526090 A JP 2014526090A JP 2014526090 A JP2014526090 A JP 2014526090A JP 2014527529 A5 JP2014527529 A5 JP 2014527529A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxy
- alkyl
- methylsulfonamido
- cyclopropyl
- fluorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161525440P | 2011-08-19 | 2011-08-19 | |
| US61/525,440 | 2011-08-19 | ||
| US201261650681P | 2012-05-23 | 2012-05-23 | |
| US61/650,681 | 2012-05-23 | ||
| PCT/US2012/050268 WO2013028371A1 (en) | 2011-08-19 | 2012-08-10 | Benzofuran compounds for the treatment of hepatitis c virus infections |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016249387A Division JP2017125010A (ja) | 2011-08-19 | 2016-12-22 | Ｃ型肝炎ウイルス感染の治療のためのベンゾフラン化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014527529A JP2014527529A (ja) | 2014-10-16 |
| JP2014527529A5 true JP2014527529A5 (enExample) | 2015-09-17 |
| JP6367712B2 JP6367712B2 (ja) | 2018-08-01 |
Family
ID=47746761
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014526090A Expired - Fee Related JP6367712B2 (ja) | 2011-08-19 | 2012-08-10 | Ｃ型肝炎ウイルス感染の治療のためのベンゾフラン化合物 |
| JP2016249387A Pending JP2017125010A (ja) | 2011-08-19 | 2016-12-22 | Ｃ型肝炎ウイルス感染の治療のためのベンゾフラン化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016249387A Pending JP2017125010A (ja) | 2011-08-19 | 2016-12-22 | Ｃ型肝炎ウイルス感染の治療のためのベンゾフラン化合物 |
Country Status (38)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH12014500381A1 (en) | 2011-08-17 | 2021-07-12 | Glaxosmithkline Llc | Therapeutic methods |
| US8927593B2 (en) | 2011-08-19 | 2015-01-06 | Glaxo Group Limited | Benzofuran compounds for the treatment of hepatitis C virus infections |
| MA40844A (fr) | 2014-11-10 | 2017-09-20 | Glaxosmithkline Ip No 2 Ltd | Compositions pharmaceutiques à action prolongée pour l'hépatite c |
| US10308937B2 (en) * | 2014-11-10 | 2019-06-04 | Glaxosmithkline Intellectual Property (No. 2) Limited | Combination long acting compositions and methods for Hepatitis C |
| KR20180006522A (ko) | 2016-07-07 | 2018-01-18 | 삼성디스플레이 주식회사 | 액정 조성물 및 이를 포함하는 액정 표시 장치 |
| US11738088B2 (en) | 2016-08-01 | 2023-08-29 | University of Pittsburgh—of the Commonwealth System of Higher Education | Boryl ethers, carbonates, and cyclic acetals as oxidatively-triggered drug delivery vehicles |
| BR112019018230A2 (pt) * | 2017-03-02 | 2020-07-21 | Assembly Biosciences, Inc. | compostos de sulfamida cíclica e métodos de sua utilização |
| JP7133023B2 (ja) * | 2018-01-17 | 2022-09-07 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | Ｐｉ４ｋｉｉｉベータ阻害剤 |
| US20230038124A1 (en) * | 2019-10-25 | 2023-02-09 | Sumitomo Pharma Co., Ltd. | Novel substituted condensed ring compound |
| CN111026203B (zh) * | 2019-12-02 | 2021-01-26 | 宁波德晶元科技有限公司 | 一种适用于真空热水壶的加热控制方法与系统 |
| WO2022133420A1 (en) * | 2020-12-18 | 2022-06-23 | Boehringer Ingelheim Animal Health USA Inc. | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083903A (en) | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| WO2001002424A2 (en) * | 1999-07-07 | 2001-01-11 | Du Pont Pharmaceuticals Company | Peptide boronic acid inhibitors of hepatitis c virus protease |
| CA2435146C (en) | 2001-01-25 | 2011-03-29 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Formulation of boronic acid compounds |
| US7265152B2 (en) * | 2002-11-01 | 2007-09-04 | Viropharma Incorporated | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases |
| BRPI0619132A2 (pt) | 2005-12-01 | 2011-09-13 | Wyeth Corp | composto métodos para inibir a replicação de um vìrus de hepatite c, para tratar ou prevenir uma infecção viral de hepatite c em um mamìfero e para inibir rna polimerase dependente do rna de hepatite c, e, composição farmacêutica |
| RU2642628C2 (ru) | 2006-02-16 | 2018-01-25 | Анакор Фармасьютикалз, Инк. | Бор-содержащие малые молекулы в качестве противовоспалительных средств |
| BRPI0711155A2 (pt) * | 2006-05-02 | 2011-08-23 | Anacor Pharmaceuticals Inc | terapêuticos contendo boro resistentes hidroliticamente e métodos de uso |
| US20070286822A1 (en) | 2006-06-12 | 2007-12-13 | Anacor Pharmaceuticals Inc. | Compounds for the Treatment of Periodontal Disease |
| ES2569660T3 (es) * | 2007-06-08 | 2016-05-12 | Mannkind Corporation | Inhibidores de la IRE-1alfa |
| GB0719366D0 (en) * | 2007-10-03 | 2007-11-14 | Smithkline Beecham Corp | Compounds |
| WO2009111676A2 (en) | 2008-03-06 | 2009-09-11 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules as anti-inflammatory agents |
| ATE539070T1 (de) * | 2008-02-14 | 2012-01-15 | Hoffmann La Roche | Heterozyklische antivirale verbindungen |
| WO2009137493A1 (en) | 2008-05-05 | 2009-11-12 | Wyeth | 2-substituted benzofuran compounds to treat infection with hepatitis c virus |
| WO2009137500A1 (en) * | 2008-05-05 | 2009-11-12 | Wyeth | 6-substituted benzofuran compounds to treat infection with hepatitis c virus |
| TW201008933A (en) | 2008-08-29 | 2010-03-01 | Hutchison Medipharma Entpr Ltd | Pyrimidine compounds |
| WO2010027975A1 (en) | 2008-09-04 | 2010-03-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| WO2011050284A1 (en) * | 2009-10-23 | 2011-04-28 | Glaxosmithkline Llc | Pyrazolylpyridine antiviral agents |
| AR080185A1 (es) * | 2010-02-19 | 2012-03-21 | Glaxo Group Ltd | Derivados de acido boronico y benzofurano, composiciones farmaceuticas que los contienen,y uso de los mismos en el tratamiento y/o prevencion de infecciones virales, en particular por el virus de hepatitis c(hcv). |
| WO2011106929A1 (en) | 2010-03-02 | 2011-09-09 | Merck Sharp & Dohme Corp. | Inhibitors of hepatitis c virus ns5b polymerase |
| TW201136919A (en) | 2010-03-02 | 2011-11-01 | Merck Sharp & Amp Dohme Corp | Inhibitors of hepatitis C virus NS5B polymerase |
| AU2011329485A1 (en) * | 2010-11-18 | 2013-04-18 | Glaxo Group Limited | Compounds |
| AU2011329486A1 (en) | 2010-11-18 | 2013-04-18 | Glaxo Group Limited | Compounds |
| WO2013025975A1 (en) * | 2011-08-17 | 2013-02-21 | Glaxosmithkline Llc | Combination treatments for hepatitis c |
| PH12014500381A1 (en) * | 2011-08-17 | 2021-07-12 | Glaxosmithkline Llc | Therapeutic methods |
| US8927593B2 (en) | 2011-08-19 | 2015-01-06 | Glaxo Group Limited | Benzofuran compounds for the treatment of hepatitis C virus infections |
-
2012
- 2012-08-10 US US13/885,500 patent/US8927593B2/en not_active Expired - Fee Related
- 2012-08-10 PH PH1/2014/500385A patent/PH12014500385A1/en unknown
- 2012-08-10 LT LTEP12826498.3T patent/LT2744332T/lt unknown
- 2012-08-10 AU AU2012299295A patent/AU2012299295B2/en not_active Ceased
- 2012-08-10 DK DK12826498.3T patent/DK2744332T3/en active
- 2012-08-10 BR BR112014002845A patent/BR112014002845A2/pt not_active Application Discontinuation
- 2012-08-10 MX MX2014001989A patent/MX354676B/es active IP Right Grant
- 2012-08-10 SG SG10201606883QA patent/SG10201606883QA/en unknown
- 2012-08-10 ME MEP-2016-287A patent/ME02588B/me unknown
- 2012-08-10 PL PL12826498T patent/PL2744332T3/pl unknown
- 2012-08-10 CN CN201280040219.3A patent/CN103732065B/zh not_active Expired - Fee Related
- 2012-08-10 ES ES12826498.3T patent/ES2611731T3/es active Active
- 2012-08-10 SI SI201230826A patent/SI2744332T1/sl unknown
- 2012-08-10 EP EP12826498.3A patent/EP2744332B1/en active Active
- 2012-08-10 WO PCT/US2012/050268 patent/WO2013028371A1/en not_active Ceased
- 2012-08-10 EP EP16195408.6A patent/EP3199531A1/en not_active Withdrawn
- 2012-08-10 SM SM20170028T patent/SMT201700028T1/it unknown
- 2012-08-10 PE PE2014000197A patent/PE20141201A1/es not_active Application Discontinuation
- 2012-08-10 HR HRP20161743TT patent/HRP20161743T1/hr unknown
- 2012-08-10 IN IN572CHN2014 patent/IN2014CN00572A/en unknown
- 2012-08-10 EA EA201490213A patent/EA032841B1/ru not_active IP Right Cessation
- 2012-08-10 CA CA2844086A patent/CA2844086A1/en not_active Abandoned
- 2012-08-10 HU HUE12826498A patent/HUE030300T2/en unknown
- 2012-08-10 RS RS20161131A patent/RS55462B1/sr unknown
- 2012-08-10 JP JP2014526090A patent/JP6367712B2/ja not_active Expired - Fee Related
- 2012-08-10 PT PT128264983T patent/PT2744332T/pt unknown
- 2012-08-10 KR KR1020147007196A patent/KR101913800B1/ko not_active Expired - Fee Related
- 2012-08-16 JO JOP/2012/0233A patent/JO3281B1/ar active
- 2012-08-16 AR ARP120103008A patent/AR087563A1/es unknown
- 2012-08-17 UY UY0001034274A patent/UY34274A/es not_active Application Discontinuation
- 2012-08-17 TW TW101130017A patent/TWI538915B/zh not_active IP Right Cessation
-
2014
- 2014-01-16 IL IL230487A patent/IL230487B/en not_active IP Right Cessation
- 2014-01-23 CO CO14013113A patent/CO6862153A2/es active IP Right Grant
- 2014-02-10 ZA ZA201401020A patent/ZA201401020B/en unknown
- 2014-02-17 CL CL2014000393A patent/CL2014000393A1/es unknown
- 2014-02-18 CR CR20140078A patent/CR20140078A/es unknown
- 2014-02-19 DO DO2014000034A patent/DOP2014000034A/es unknown
- 2014-03-13 MA MA36832A patent/MA35443B1/fr unknown
- 2014-11-20 US US14/548,524 patent/US9682999B2/en not_active Expired - Fee Related
-
2016
- 2016-12-22 JP JP2016249387A patent/JP2017125010A/ja active Pending
- 2016-12-27 CY CY20161101345T patent/CY1118399T1/el unknown
-
2017
- 2017-01-18 SM SM201700028T patent/SMT201700028B/it unknown
- 2017-02-03 CL CL2017000293A patent/CL2017000293A1/es unknown
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