JP2014520852A5 - - Google Patents
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- Publication number
- JP2014520852A5 JP2014520852A5 JP2014520273A JP2014520273A JP2014520852A5 JP 2014520852 A5 JP2014520852 A5 JP 2014520852A5 JP 2014520273 A JP2014520273 A JP 2014520273A JP 2014520273 A JP2014520273 A JP 2014520273A JP 2014520852 A5 JP2014520852 A5 JP 2014520852A5
- Authority
- JP
- Japan
- Prior art keywords
- buffer composition
- norovirus
- genogroup
- buffer
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 24
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 9
- 241001263478 Norovirus Species 0.000 claims 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 8
- 235000002639 sodium chloride Nutrition 0.000 claims 7
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-Histidine Natural products OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 5
- 239000011780 sodium chloride Substances 0.000 claims 4
- 229960002885 histidine Drugs 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229940035032 monophosphoryl lipid a Drugs 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 229940037003 alum Drugs 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 108090000565 Capsid Proteins Proteins 0.000 claims 1
- 102100023321 Ceruloplasmin Human genes 0.000 claims 1
- 108091035707 Consensus sequence Proteins 0.000 claims 1
- 125000002066 L-histidyl group Chemical group [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 claims 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims 1
- 235000011130 ammonium sulphate Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000001103 potassium chloride Substances 0.000 claims 1
- 235000011164 potassium chloride Nutrition 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- 235000011083 sodium citrates Nutrition 0.000 claims 1
- 229910052938 sodium sulfate Inorganic materials 0.000 claims 1
- 235000011152 sodium sulphate Nutrition 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161506447P | 2011-07-11 | 2011-07-11 | |
| US61/506,447 | 2011-07-11 | ||
| PCT/US2012/046222 WO2013009849A1 (en) | 2011-07-11 | 2012-07-11 | Parenteral norovirus vaccine formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017091755A Division JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014520852A JP2014520852A (ja) | 2014-08-25 |
| JP2014520852A5 true JP2014520852A5 (enExample) | 2015-09-03 |
| JP6208659B2 JP6208659B2 (ja) | 2017-10-04 |
Family
ID=47506489
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014520273A Active JP6208659B2 (ja) | 2011-07-11 | 2012-07-11 | 非経口ノロウイルスワクチン製剤 |
| JP2017091755A Active JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017091755A Active JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Country Status (29)
| Country | Link |
|---|---|
| US (5) | US9801934B2 (enExample) |
| EP (3) | EP2731621B1 (enExample) |
| JP (2) | JP6208659B2 (enExample) |
| KR (1) | KR102096937B1 (enExample) |
| CN (3) | CN108567975A (enExample) |
| AU (2) | AU2012282658B2 (enExample) |
| BR (1) | BR112014000656A2 (enExample) |
| CA (1) | CA2841356C (enExample) |
| CL (1) | CL2014000082A1 (enExample) |
| CR (2) | CR20190540A (enExample) |
| DK (1) | DK3299030T3 (enExample) |
| DO (2) | DOP2014000004A (enExample) |
| EA (3) | EA035442B1 (enExample) |
| EC (1) | ECSP14013201A (enExample) |
| ES (2) | ES2656527T3 (enExample) |
| GE (1) | GEP201706668B (enExample) |
| HK (2) | HK1199202A1 (enExample) |
| IL (1) | IL230356B (enExample) |
| MA (1) | MA35414B1 (enExample) |
| MX (2) | MX379496B (enExample) |
| MY (1) | MY170746A (enExample) |
| PE (1) | PE20140845A1 (enExample) |
| PH (3) | PH12014500093A1 (enExample) |
| PL (2) | PL2731621T3 (enExample) |
| SG (1) | SG10201605644WA (enExample) |
| TN (1) | TN2014000008A1 (enExample) |
| UA (1) | UA117732C2 (enExample) |
| WO (1) | WO2013009849A1 (enExample) |
| ZA (2) | ZA201401012B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009039229A2 (en) | 2007-09-18 | 2009-03-26 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| SI2601970T1 (sl) | 2006-09-29 | 2017-04-26 | Takeda Vaccines, Inc. | Formulacije cepiva proti norovirusu |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| EP2731621B1 (en) | 2011-07-11 | 2017-11-01 | Takeda Vaccines, Inc. | Parenteral norovirus vaccine formulations |
| SG10202107054TA (en) | 2013-10-03 | 2021-08-30 | Takeda Vaccines Inc | Methods of detection and removal of rhabdoviruses from cell lines |
| EP3085357B1 (en) | 2013-12-16 | 2019-02-13 | Takeda Pharmaceutical Company Limited | Microneedle |
| CN107184970A (zh) * | 2017-02-16 | 2017-09-22 | 北京生物制品研究所有限责任公司 | 口服诺如病毒亚单位疫苗及lt作为该疫苗佐剂的用途 |
| GB201703644D0 (en) | 2017-03-07 | 2017-04-19 | Elopak As | Improvements in or relating to toller mounting arrangements |
| EP3624851A1 (en) * | 2017-05-15 | 2020-03-25 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
| WO2019158653A1 (en) * | 2018-02-15 | 2019-08-22 | Icon Genetics Gmbh | Immunogenic composition and vaccine for generating an immune response to norovirus |
| WO2019231712A1 (en) * | 2018-05-29 | 2019-12-05 | Stc.Unm | Virus-like particle compositions and methods of using same |
| CN109265542B (zh) * | 2018-09-27 | 2021-06-15 | 国药中生生物技术研究院有限公司 | 特异性结合诺如病毒gii.4基因型vp1蛋白或vlp的抗体及其制备方法和应用 |
| AR117462A1 (es) * | 2018-12-20 | 2021-08-04 | Takeda Vaccines Inc | Vacuna contra norovirus, formulaciones y métodos |
| BR112022013537A2 (pt) * | 2020-01-08 | 2022-11-22 | Bharat Biotech Int Ltd | Composições de vacina viral e métodos de preparações das mesmas |
| US20240156942A1 (en) | 2021-03-29 | 2024-05-16 | Denka Company Limited | Peptide of Norovirus Origin, Polynucleotide, Antibody, Composition, Method for Identifying Neutralizing Epitope for Norovirus |
| EP4340874A1 (en) | 2021-05-21 | 2024-03-27 | Takeda Vaccines, Inc. | Solid composition, freeze-drying method and glass vial |
| CN118252924A (zh) * | 2022-12-27 | 2024-06-28 | 远大赛威信生命科学(南京)有限公司 | 用于诱发哺乳动物针对诺如病毒的免疫反应的药物组合物及其制备方法和用途 |
| WO2025077799A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Method of preparing norovirus vaccine without adjuvant |
| WO2025076792A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Product Co., Ltd. | Methods of preparing norovirus vaccine with low amounts of adjuvant |
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| AU4851493A (en) | 1992-09-07 | 1994-03-29 | Baylor College Of Medicine | Methods and reagents to detect and characterize norwalk and related viruses |
| WO1994021292A1 (en) | 1993-03-23 | 1994-09-29 | Smithkline Beecham Biologicals (S.A.) | Vaccine compositions containing 3-o deacylated monophosphoryl lipid a |
| US5788970A (en) | 1994-03-29 | 1998-08-04 | The University Of Maryland College Park | Chimeric infectious bursal disease virus CDNA clones, expression products and vaccines based thereon |
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2012
- 2012-07-11 EP EP12811916.1A patent/EP2731621B1/en active Active
- 2012-07-11 PE PE2014000054A patent/PE20140845A1/es active IP Right Grant
- 2012-07-11 EP EP17199372.8A patent/EP3299030B1/en active Active
- 2012-07-11 EA EA201792407A patent/EA035442B1/ru not_active IP Right Cessation
- 2012-07-11 EA EA201490258A patent/EA029470B1/ru not_active IP Right Cessation
- 2012-07-11 AU AU2012282658A patent/AU2012282658B2/en active Active
- 2012-07-11 ES ES12811916.1T patent/ES2656527T3/es active Active
- 2012-07-11 MY MYPI2014000073A patent/MY170746A/en unknown
- 2012-07-11 BR BR112014000656A patent/BR112014000656A2/pt not_active Application Discontinuation
- 2012-07-11 SG SG10201605644WA patent/SG10201605644WA/en unknown
- 2012-07-11 PL PL12811916T patent/PL2731621T3/pl unknown
- 2012-07-11 JP JP2014520273A patent/JP6208659B2/ja active Active
- 2012-07-11 CR CR20190540A patent/CR20190540A/es unknown
- 2012-07-11 KR KR1020147003571A patent/KR102096937B1/ko active Active
- 2012-07-11 MX MX2018006816A patent/MX379496B/es unknown
- 2012-07-11 HK HK14112697.5A patent/HK1199202A1/xx unknown
- 2012-07-11 WO PCT/US2012/046222 patent/WO2013009849A1/en not_active Ceased
- 2012-07-11 PH PH1/2014/500093A patent/PH12014500093A1/en unknown
- 2012-07-11 EA EA202090699A patent/EA202090699A3/ru unknown
- 2012-07-11 PH PH1/2021/551773A patent/PH12021551773A1/en unknown
- 2012-07-11 GE GEAP201213384A patent/GEP201706668B/en unknown
- 2012-07-11 CN CN201810373895.1A patent/CN108567975A/zh active Pending
- 2012-07-11 ES ES17199372T patent/ES2926487T3/es active Active
- 2012-07-11 DK DK17199372.8T patent/DK3299030T3/da active
- 2012-07-11 CA CA2841356A patent/CA2841356C/en active Active
- 2012-07-11 EP EP22176978.9A patent/EP4112074A1/en active Pending
- 2012-07-11 MX MX2014000411A patent/MX356586B/es active IP Right Grant
- 2012-07-11 PL PL17199372.8T patent/PL3299030T3/pl unknown
- 2012-07-11 CN CN201280043691.2A patent/CN103874507A/zh active Pending
- 2012-07-11 CN CN201510262891.2A patent/CN105031637A/zh active Pending
- 2012-11-07 UA UAA201401321A patent/UA117732C2/uk unknown
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2013
- 2013-03-15 US US13/840,403 patent/US9801934B2/en active Active
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2014
- 2014-01-07 IL IL230356A patent/IL230356B/en active IP Right Grant
- 2014-01-07 TN TNP2014000008A patent/TN2014000008A1/en unknown
- 2014-01-10 DO DO2014000004A patent/DOP2014000004A/es unknown
- 2014-01-10 CL CL2014000082A patent/CL2014000082A1/es unknown
- 2014-02-06 MA MA36741A patent/MA35414B1/fr unknown
- 2014-02-10 ZA ZA2014/01012A patent/ZA201401012B/en unknown
- 2014-02-11 CR CR20140069A patent/CR20140069A/es unknown
- 2014-02-11 EC ECSP14013201 patent/ECSP14013201A/es unknown
- 2014-12-18 HK HK16102061.2A patent/HK1215154A1/zh unknown
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2015
- 2015-02-09 ZA ZA2015/00915A patent/ZA201500915B/en unknown
- 2015-02-19 AU AU2015200836A patent/AU2015200836B2/en active Active
- 2015-07-10 US US14/796,614 patent/US9867876B2/en active Active
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2017
- 2017-05-02 JP JP2017091755A patent/JP6613259B2/ja active Active
- 2017-12-08 US US15/836,030 patent/US10675341B2/en active Active
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2018
- 2018-07-06 PH PH12018501515A patent/PH12018501515B1/en unknown
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2020
- 2020-06-05 US US16/894,291 patent/US11701420B2/en active Active
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2022
- 2022-02-04 DO DO2022000030A patent/DOP2022000030A/es unknown
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2023
- 2023-05-24 US US18/322,679 patent/US20230338503A1/en not_active Abandoned