JP2014520852A5 - - Google Patents
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- Publication number
- JP2014520852A5 JP2014520852A5 JP2014520273A JP2014520273A JP2014520852A5 JP 2014520852 A5 JP2014520852 A5 JP 2014520852A5 JP 2014520273 A JP2014520273 A JP 2014520273A JP 2014520273 A JP2014520273 A JP 2014520273A JP 2014520852 A5 JP2014520852 A5 JP 2014520852A5
- Authority
- JP
- Japan
- Prior art keywords
- buffer composition
- norovirus
- genogroup
- buffer
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 24
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 9
- 241001263478 Norovirus Species 0.000 claims 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 8
- 235000002639 sodium chloride Nutrition 0.000 claims 7
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-Histidine Natural products OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 5
- 239000011780 sodium chloride Substances 0.000 claims 4
- 229960002885 histidine Drugs 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229940035032 monophosphoryl lipid a Drugs 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 229940037003 alum Drugs 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 108090000565 Capsid Proteins Proteins 0.000 claims 1
- 102100023321 Ceruloplasmin Human genes 0.000 claims 1
- 108091035707 Consensus sequence Proteins 0.000 claims 1
- 125000002066 L-histidyl group Chemical group [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 claims 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims 1
- 235000011130 ammonium sulphate Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000001103 potassium chloride Substances 0.000 claims 1
- 235000011164 potassium chloride Nutrition 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- 235000011083 sodium citrates Nutrition 0.000 claims 1
- 229910052938 sodium sulfate Inorganic materials 0.000 claims 1
- 235000011152 sodium sulphate Nutrition 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161506447P | 2011-07-11 | 2011-07-11 | |
| US61/506,447 | 2011-07-11 | ||
| PCT/US2012/046222 WO2013009849A1 (en) | 2011-07-11 | 2012-07-11 | Parenteral norovirus vaccine formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017091755A Division JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014520852A JP2014520852A (ja) | 2014-08-25 |
| JP2014520852A5 true JP2014520852A5 (OSRAM) | 2015-09-03 |
| JP6208659B2 JP6208659B2 (ja) | 2017-10-04 |
Family
ID=47506489
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014520273A Active JP6208659B2 (ja) | 2011-07-11 | 2012-07-11 | 非経口ノロウイルスワクチン製剤 |
| JP2017091755A Active JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017091755A Active JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Country Status (29)
| Country | Link |
|---|---|
| US (5) | US9801934B2 (OSRAM) |
| EP (3) | EP3299030B1 (OSRAM) |
| JP (2) | JP6208659B2 (OSRAM) |
| KR (1) | KR102096937B1 (OSRAM) |
| CN (3) | CN108567975A (OSRAM) |
| AU (2) | AU2012282658B2 (OSRAM) |
| BR (1) | BR112014000656A2 (OSRAM) |
| CA (1) | CA2841356C (OSRAM) |
| CL (1) | CL2014000082A1 (OSRAM) |
| CR (2) | CR20190540A (OSRAM) |
| DK (1) | DK3299030T3 (OSRAM) |
| DO (2) | DOP2014000004A (OSRAM) |
| EA (3) | EA202090699A3 (OSRAM) |
| EC (1) | ECSP14013201A (OSRAM) |
| ES (2) | ES2926487T3 (OSRAM) |
| GE (1) | GEP201706668B (OSRAM) |
| HK (2) | HK1199202A1 (OSRAM) |
| IL (1) | IL230356B (OSRAM) |
| MA (1) | MA35414B1 (OSRAM) |
| MX (2) | MX379496B (OSRAM) |
| MY (1) | MY170746A (OSRAM) |
| PE (1) | PE20140845A1 (OSRAM) |
| PH (3) | PH12014500093A1 (OSRAM) |
| PL (2) | PL2731621T3 (OSRAM) |
| SG (1) | SG10201605644WA (OSRAM) |
| TN (1) | TN2014000008A1 (OSRAM) |
| UA (1) | UA117732C2 (OSRAM) |
| WO (1) | WO2013009849A1 (OSRAM) |
| ZA (2) | ZA201401012B (OSRAM) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2618885T3 (es) | 2006-09-29 | 2017-06-22 | Takeda Vaccines, Inc. | Formulaciones de vacuna para norovirus |
| KR20100083150A (ko) | 2007-09-18 | 2010-07-21 | 리고사이트 파머슈티컬즈 인코퍼레이티드 | 노로바이러스에 대한 보호면역반응을 제공하는 방법 |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| HK1199202A1 (en) | 2011-07-11 | 2015-06-26 | 武田疫苗股份有限公司 | Parenteral norovirus vaccine formulations |
| KR102474663B1 (ko) | 2013-10-03 | 2022-12-07 | 다케다 백신즈 인코포레이티드 | 세포주로부터 랍도바이러스를 탐지 및 제거하는 방법 |
| US20160310412A1 (en) | 2013-12-16 | 2016-10-27 | Takeda Pharmaceutical Company Limited | Microneedle |
| CN107184970A (zh) * | 2017-02-16 | 2017-09-22 | 北京生物制品研究所有限责任公司 | 口服诺如病毒亚单位疫苗及lt作为该疫苗佐剂的用途 |
| GB201703644D0 (en) | 2017-03-07 | 2017-04-19 | Elopak As | Improvements in or relating to toller mounting arrangements |
| US11306292B2 (en) * | 2017-05-15 | 2022-04-19 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
| EP3752185A1 (en) * | 2018-02-15 | 2020-12-23 | Icon Genetics GmbH | Immunogenic composition and vaccine for generating an immune response to norovirus |
| WO2019231712A1 (en) * | 2018-05-29 | 2019-12-05 | Stc.Unm | Virus-like particle compositions and methods of using same |
| CN109265542B (zh) * | 2018-09-27 | 2021-06-15 | 国药中生生物技术研究院有限公司 | 特异性结合诺如病毒gii.4基因型vp1蛋白或vlp的抗体及其制备方法和应用 |
| AR117462A1 (es) * | 2018-12-20 | 2021-08-04 | Takeda Vaccines Inc | Vacuna contra norovirus, formulaciones y métodos |
| BR112022013537A2 (pt) | 2020-01-08 | 2022-11-22 | Bharat Biotech Int Ltd | Composições de vacina viral e métodos de preparações das mesmas |
| KR20230140464A (ko) | 2021-03-29 | 2023-10-06 | 덴카 주식회사 | 노로바이러스 유래의 펩티드, 폴리뉴클레오티드, 항체, 조성물, 노로바이러스의 중화 에피토프를 동정하는 방법 |
| WO2022246323A1 (en) | 2021-05-21 | 2022-11-24 | Takeda Vaccines, Inc. | Solid composition, freeze-drying method and glass vial |
| CN118252924A (zh) * | 2022-12-27 | 2024-06-28 | 远大赛威信生命科学(南京)有限公司 | 用于诱发哺乳动物针对诺如病毒的免疫反应的药物组合物及其制备方法和用途 |
| WO2025077799A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Method of preparing norovirus vaccine without adjuvant |
| WO2025076792A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Product Co., Ltd. | Methods of preparing norovirus vaccine with low amounts of adjuvant |
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2012
- 2012-07-11 HK HK14112697.5A patent/HK1199202A1/xx unknown
- 2012-07-11 EA EA202090699A patent/EA202090699A3/ru unknown
- 2012-07-11 WO PCT/US2012/046222 patent/WO2013009849A1/en not_active Ceased
- 2012-07-11 EP EP17199372.8A patent/EP3299030B1/en active Active
- 2012-07-11 MY MYPI2014000073A patent/MY170746A/en unknown
- 2012-07-11 GE GEAP201213384A patent/GEP201706668B/en unknown
- 2012-07-11 AU AU2012282658A patent/AU2012282658B2/en active Active
- 2012-07-11 KR KR1020147003571A patent/KR102096937B1/ko active Active
- 2012-07-11 PH PH1/2014/500093A patent/PH12014500093A1/en unknown
- 2012-07-11 PE PE2014000054A patent/PE20140845A1/es active IP Right Grant
- 2012-07-11 BR BR112014000656A patent/BR112014000656A2/pt not_active Application Discontinuation
- 2012-07-11 CN CN201810373895.1A patent/CN108567975A/zh active Pending
- 2012-07-11 PH PH1/2021/551773A patent/PH12021551773A1/en unknown
- 2012-07-11 EA EA201490258A patent/EA029470B1/ru not_active IP Right Cessation
- 2012-07-11 CN CN201280043691.2A patent/CN103874507A/zh active Pending
- 2012-07-11 MX MX2018006816A patent/MX379496B/es unknown
- 2012-07-11 ES ES17199372T patent/ES2926487T3/es active Active
- 2012-07-11 JP JP2014520273A patent/JP6208659B2/ja active Active
- 2012-07-11 DK DK17199372.8T patent/DK3299030T3/da active
- 2012-07-11 PL PL12811916T patent/PL2731621T3/pl unknown
- 2012-07-11 EP EP22176978.9A patent/EP4112074A1/en active Pending
- 2012-07-11 EA EA201792407A patent/EA035442B1/ru not_active IP Right Cessation
- 2012-07-11 EP EP12811916.1A patent/EP2731621B1/en active Active
- 2012-07-11 CA CA2841356A patent/CA2841356C/en active Active
- 2012-07-11 CR CR20190540A patent/CR20190540A/es unknown
- 2012-07-11 CN CN201510262891.2A patent/CN105031637A/zh active Pending
- 2012-07-11 MX MX2014000411A patent/MX356586B/es active IP Right Grant
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