JP2013523704A5 - - Google Patents

Download PDF

Info

Publication number
JP2013523704A5
JP2013523704A5 JP2013501930A JP2013501930A JP2013523704A5 JP 2013523704 A5 JP2013523704 A5 JP 2013523704A5 JP 2013501930 A JP2013501930 A JP 2013501930A JP 2013501930 A JP2013501930 A JP 2013501930A JP 2013523704 A5 JP2013523704 A5 JP 2013523704A5
Authority
JP
Japan
Prior art keywords
virus
solution
additive
alkyl
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013501930A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013523704A (ja
JP5869553B2 (ja
Filing date
Publication date
Priority claimed from GBGB1005517.6A external-priority patent/GB201005517D0/en
Priority claimed from GBGB1005521.8A external-priority patent/GB201005521D0/en
Priority claimed from GBGB1017648.5A external-priority patent/GB201017648D0/en
Application filed filed Critical
Priority claimed from PCT/GB2011/000493 external-priority patent/WO2011121301A1/en
Publication of JP2013523704A publication Critical patent/JP2013523704A/ja
Publication of JP2013523704A5 publication Critical patent/JP2013523704A5/ja
Application granted granted Critical
Publication of JP5869553B2 publication Critical patent/JP5869553B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013501930A 2010-03-31 2011-03-31 ウイルス粒子、ポリペプチド又は生体材料を安定化させる添加剤 Active JP5869553B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB1005517.6A GB201005517D0 (en) 2010-03-31 2010-03-31 Stabilised liquid formulations of polypeptides
GB1005517.6 2010-03-31
GB1005521.8 2010-03-31
GBGB1005521.8A GB201005521D0 (en) 2010-03-31 2010-03-31 Stabilised liquid formulations of virus particles
GBGB1017648.5A GB201017648D0 (en) 2010-10-19 2010-10-19 Liquid preparation containing stabilised viruses
GB1017648.5 2010-10-19
PCT/GB2011/000493 WO2011121301A1 (en) 2010-03-31 2011-03-31 Excipients for stabilising viral particles, polypeptides or biological material

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016001536A Division JP6053969B2 (ja) 2010-03-31 2016-01-07 ウイルス粒子、ポリペプチド又は生体材料を安定化させる添加剤

Publications (3)

Publication Number Publication Date
JP2013523704A JP2013523704A (ja) 2013-06-17
JP2013523704A5 true JP2013523704A5 (OSRAM) 2014-04-17
JP5869553B2 JP5869553B2 (ja) 2016-02-24

Family

ID=43902836

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013501930A Active JP5869553B2 (ja) 2010-03-31 2011-03-31 ウイルス粒子、ポリペプチド又は生体材料を安定化させる添加剤
JP2016001536A Active JP6053969B2 (ja) 2010-03-31 2016-01-07 ウイルス粒子、ポリペプチド又は生体材料を安定化させる添加剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016001536A Active JP6053969B2 (ja) 2010-03-31 2016-01-07 ウイルス粒子、ポリペプチド又は生体材料を安定化させる添加剤

Country Status (15)

Country Link
US (2) US20130164296A1 (OSRAM)
EP (1) EP2552478B1 (OSRAM)
JP (2) JP5869553B2 (OSRAM)
KR (2) KR101943429B1 (OSRAM)
CN (1) CN102892427A (OSRAM)
AU (2) AU2011234264B2 (OSRAM)
BR (1) BR112012025047A2 (OSRAM)
CA (1) CA2795047C (OSRAM)
DK (1) DK2552478T3 (OSRAM)
ES (1) ES2617921T3 (OSRAM)
GB (1) GB2490644A (OSRAM)
HU (1) HUE033656T2 (OSRAM)
IL (1) IL221857A (OSRAM)
WO (1) WO2011121301A1 (OSRAM)
ZA (1) ZA201206956B (OSRAM)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE033656T2 (en) 2010-03-31 2017-12-28 Stabilitech Ltd Binders for stabilizing virus particles
EP2898890B1 (en) * 2010-03-31 2019-08-21 Stabilitech Biopharma Ltd Stabilisation of viral particles
GB201117233D0 (en) * 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
GB201208293D0 (en) * 2012-05-11 2012-06-20 Circassia Ltd Hydrochlorice salt of peptide
US9622483B2 (en) 2014-02-19 2017-04-18 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039620B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039621B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
GB201406569D0 (en) * 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB201513010D0 (en) 2015-07-23 2015-09-09 Glaxosmithkline Biolog Sa Novel formulation
US11015205B2 (en) 2016-12-22 2021-05-25 Leibniz-Institut für Pflanzengenetik Und Kulturpflanzenforschung (IPK) Oligomeric vaccines from plants by S-Tag-S-protein fusions
MX2019008105A (es) * 2017-01-06 2020-07-22 Stabilitech Biopharma Ltd Virus.
KR101878599B1 (ko) * 2017-03-28 2018-07-13 전북대학교산학협력단 메틸설포닐메테인과 만니톨의 흡수촉진 및 고미감소를 위한 공침조성물과 이의 제조방법
GB2562241B (en) * 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions
AR113996A1 (es) * 2017-12-22 2020-07-08 Intervet Int Bv Vacunas líquidas de virus envueltos vivos
JP7437385B2 (ja) 2018-09-06 2024-02-22 バヴァリアン・ノルディック・アクティーゼルスカブ 保管が改善されたポックスウイルス組成物
CN115243717A (zh) 2020-03-12 2022-10-25 巴法里安诺迪克有限公司 改善痘病毒稳定性的组合物
CN114649066B (zh) * 2020-12-17 2025-02-11 南开大学 一种提升d-氨基酸减缓mbr膜污染效能的智能优化方法
JP7748616B2 (ja) * 2021-03-24 2025-10-03 大日本印刷株式会社 液体入り組合せ容器、容器セットおよび液体入り容器の製造方法
CN114392237B (zh) * 2021-12-28 2024-02-02 上海允英生物医药科技有限公司 一种冻干病毒制剂及其制备方法

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3927208A (en) * 1973-05-14 1975-12-16 Rit Rech Ind Therapeut Live bovine adenovirus vaccines, preparation thereof and method of vaccination using them
US4631189A (en) 1980-03-10 1986-12-23 Da Vinci Laboratories, a division of FoodScience Corporation N,N-dimethylglycine and use in immune response
JPS6013718A (ja) 1983-07-05 1985-01-24 Chemo Sero Therapeut Res Inst B型肝炎ワクチン
JPS60193925A (ja) 1984-03-13 1985-10-02 Chemo Sero Therapeut Res Inst 凍結乾燥製剤化ワクチン
US4808700A (en) * 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
JPS61189228A (ja) 1985-02-19 1986-08-22 Nippon Sekijiyuujishiya 血液凝固第8因子製剤の製法
US4950596A (en) 1985-03-04 1990-08-21 The Dow Chemical Company Stabilization of intracellular enzymes
JPS6238173A (ja) * 1985-08-13 1987-02-19 三菱レイヨン株式会社 抗血液凝固剤
US5169758A (en) 1986-05-02 1992-12-08 Boehringer Mannheim Gmbh Stabilized, NAD(P)H-dependent, soluble nitrate reductase, a process for the preparation thereof and a reagent containing it
US4816568A (en) 1986-05-16 1989-03-28 International Minerals & Chemical Corp. Stabilization of growth hormones
NZ221306A (en) 1986-08-15 1990-02-26 Commw Scient Ind Res Org 2-component immunoadjuvant comprising a mycobacterial free immunoadjuvant oil and a polycationic polyelectrolyte immunoadjuvant and vaccines thereof
US4980277A (en) * 1987-10-16 1990-12-25 Cultor Ltd. Cryoprotectant solution and method
EP0417193B1 (en) 1988-05-27 1993-08-04 Centocor, Inc. Freeze-dried formulation for antibody products
GB8826429D0 (en) 1988-11-11 1988-12-14 Univ Leeds Ind Service Ltd Enzyme stabilisation systems
DK0487632T3 (da) 1989-08-15 1998-05-25 Massachusetts Inst Technology Stabiliserede vaccinesammensætninger
AU650045B2 (en) 1990-09-12 1994-06-09 Lifecell Corporation Method and apparatus for cryopreparation dry stabilization and rehydration of biological suspensions
AU2309692A (en) 1991-07-03 1993-02-11 Cryolife, Inc. Method for stabilization of biomaterials
RU2099418C1 (ru) * 1991-11-21 1997-12-20 Лонца Аг Фрагмент днк, обеспечивающий использование бетаина, рекомбинантная плазмидная днк с фрагментом днк, обеспечивающим использование бетаина, штамм бактерий rhizobium/agrobacterium, предназначенный для стабильного хранения плазмиды с фрагментом днк, способ получения штамма бактерий
ZA936095B (en) 1992-08-21 1994-03-14 Univ Melbourne Cytokine applications.
FR2698879B1 (fr) * 1992-12-09 1995-01-13 Rhone Poulenc Biochimie gellules modifiées au niveau du catabolisme de la bétaïne, préparation et utilisations, notamment pour la production de métabolites ou d'enzymes.
GB9320782D0 (en) 1993-10-08 1993-12-01 Univ Leeds Innovations Ltd Stabilising of proteins on solution
WO1995011700A1 (en) 1993-10-29 1995-05-04 Pharmos Corp. Submicron emulsions as vaccine adjuvants
US5580856A (en) 1994-07-15 1996-12-03 Prestrelski; Steven J. Formulation of a reconstituted protein, and method and kit for the production thereof
US5965438A (en) 1995-06-07 1999-10-12 Phyton, Inc. Cryopreservation of plant cells
DK1516628T3 (da) 1995-07-27 2013-09-08 Genentech Inc Stabil, isotonisk lyofiliseret proteinformulering
GB9521806D0 (en) 1995-10-25 1996-01-03 Cortecs Ltd Preservation methods
FR2746109B1 (fr) 1996-03-12 1998-04-17 Rhone Poulenc Rorer Sa Milieu pour la conservation de materiel biologique
US20070179096A1 (en) 1996-04-24 2007-08-02 Novo Nordisk A/S Pharmaceutical Formulation
US6037116A (en) 1996-06-14 2000-03-14 Biostore New Zealand, Ltd. Compositions comprising betaine, sodium citrate and sodium chloride and methods for the preservation of biological materials
US6656734B1 (en) 1997-07-01 2003-12-02 Transgene S.A. Compositions for the delivery of polynucleotides to cells
WO1999027071A1 (en) 1997-11-26 1999-06-03 Universal Preservation Technologies, Inc. Preservation of sensitive biological samples by vitrification
WO2000029024A1 (en) 1998-11-16 2000-05-25 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
US6689600B1 (en) 1998-11-16 2004-02-10 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
AUPQ347199A0 (en) * 1999-10-15 1999-11-11 Csl Limited Novel polypeptide fragments
BR0111494A (pt) 2000-06-08 2004-01-13 Powderject Vaccines Inc Pó de livre escoamento formador de gel adequado para uso como uma vacina, processo para a preparação do mesmo, receptáculo de dosagem para uma seringa sem agulha, seringa sem agulha, composição de vacina, método para vacinação de um indivìduo, pó adequado para uso como uma vacina, e, processo para a preparação do mesmo
DE10041515A1 (de) 2000-08-24 2002-03-14 Gerold Schuler Verfahren zur Herstellung gebrauchsfertiger, Antigen-beladener oder -unbeladener, kryokonservierter reifer dendritischer Zellen
US20040110267A1 (en) 2000-12-15 2004-06-10 Stratagene Room temperature stable competent cells
WO2002101412A2 (en) 2001-06-08 2002-12-19 Powderject Vaccines, Inc. Spray freeze-dried compositions
US7101693B2 (en) 2001-09-07 2006-09-05 Brigham Young University Plasticized hydrophilic glasses for improved stabilization of biological agents
JP4936618B2 (ja) 2001-09-21 2012-05-23 株式会社ノエビア 微細エマルション組成物
US20040161776A1 (en) 2001-10-23 2004-08-19 Maddon Paul J. PSMA formulations and uses thereof
CA2471656C (en) 2001-12-28 2012-07-31 Kirin Beer Kabushiki Kaisha Antibody against fibroblast growth factor-23
EP1946776B1 (en) 2002-02-27 2017-01-18 Immunex Corporation Stabilized tnfr-fc composition comprising arginine
JP2003261591A (ja) 2002-03-08 2003-09-19 Koji Hayade 凍結乾燥安定剤
AU2003240437A1 (en) 2002-06-27 2004-01-19 Novo Nordisk A/S Use of dimethyl sulfone as isotonicity agent
US20060228334A1 (en) 2002-07-10 2006-10-12 Manuel Rosa-Calatrava Modified adenoviral fiber with ablated to cellular receptors
AU2003272174A1 (en) 2002-10-21 2004-05-04 Biotage Ab Use of osmolytes to heat stabilise luciferase and/or apyrase
EP1578305A4 (en) 2002-12-10 2008-08-27 Schering Plough Ltd CANIN RANKL AND METHODS OF PREPARATION AND USE THEREOF
EP1633391B1 (en) 2003-06-03 2011-10-19 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
JP2007537975A (ja) 2003-06-10 2007-12-27 ザ ユニバーシティー オブ メルボルン 免疫調節性組成物、それらについての使用方法およびそれらの製造のための方法
US20060247167A1 (en) 2003-09-01 2006-11-02 Novo Nordisk A/S Stable formulations of peptides
US7642077B2 (en) 2003-12-08 2010-01-05 Genencor International, Inc. Biocomposite comprising co-precipitate of enzyme, silicate and polyamine
EP1711619A4 (en) 2003-12-30 2007-04-11 Virumar Pituach Tarkivin Ltd INTEGRATED VIRUS COMPLEXES, METHOD FOR THE MANUFACTURE THEREOF, VACCINES CONTAINING THEM AND METHOD FOR THE USE THEREOF
BRPI0508440A (pt) 2004-03-03 2007-07-24 Revance Therapeutics Inc composições e métodos para diagnóstico tópico e transporte terapêutico
US20060058238A1 (en) 2004-09-15 2006-03-16 Lee Laurent-Applegate Fetal skin cell protein compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
EP3173072A1 (en) 2004-10-01 2017-05-31 Ramscor, Inc. Conveniently implantable sustained release drug compositions
RS53890B1 (sr) 2004-11-10 2015-08-31 Tolmar Therapeutics, Inc. Stabilizovan polimerni sistem za isporuku
JP2008528638A (ja) 2005-01-28 2008-07-31 ワイス ポリペプチドの安定化液体処方
GB0502661D0 (en) 2005-02-09 2005-03-16 Stabilitech Ltd A desiccated product
TWI398272B (zh) * 2005-03-08 2013-06-11 Intervet Int Bv 化學定義的安定劑
JP5020935B2 (ja) 2005-04-08 2012-09-05 アルゴス セラピューティクス,インコーポレイティド 樹状細胞組成物および方法
DK1954308T3 (da) 2005-09-16 2011-10-24 Merial Ltd Stabiliseringsmidler til frysetørrede vacciner
US20090155351A1 (en) 2005-10-04 2009-06-18 Alk-Abello A/S Solid Vaccine Formulation
EP1951865A4 (en) 2005-11-21 2010-06-23 Sanofi Pasteur Ltd STABILIZING FORMULATIONS FOR RECOMBINANT VIRUSES
CN105315347A (zh) 2005-11-30 2016-02-10 株式会社癌免疫研究所 新型肽化合物
EP1954252B1 (en) 2005-12-02 2016-02-03 GlaxoSmithKline Biologicals SA Nanoparticles for use in immunogenic compositions
WO2007095337A2 (en) 2006-02-15 2007-08-23 Imclone Systems Incorporated Antibody formulation
US8021659B2 (en) 2006-04-28 2011-09-20 Naidu Lp Coenzyme Q10, lactoferrin and angiogenin compositions and uses thereof
ES2286951B1 (es) 2006-05-26 2008-10-01 Instituto Cientifico Y Tecnologico De Navarra, S.A Nanoparticulas bioadhesivas para la administracion de moleculas biologicamente activas.
US20090053197A1 (en) 2006-06-14 2009-02-26 Ramaekers Joseph C Transfer Factor Compositions and Methods
EP2099485B1 (en) * 2006-11-03 2018-03-21 AlphaVax, Inc. Alphavirus and alphavirus replicon particle formulations and methods
GB0705245D0 (en) * 2007-03-19 2007-04-25 Stabilitech Ltd Stable biological products
DK2131857T3 (en) 2007-03-22 2015-09-14 Univ Colorado Regents A method of producing an immunologically active adjuvansbundet dried vaccine composition
EP2150537A4 (en) 2007-06-01 2010-09-22 Acologix Inc STABLE PEPTIDE FORMULATION AT HIGH TEMPERATURE
CA2692231A1 (en) 2007-06-29 2009-01-08 Advanced Technologies And Regenerative Medicine, Llc Liquid protein formulations comprising gdf-5 for use at elevated temperatures
US20090029463A1 (en) 2007-07-25 2009-01-29 Bioe, Inc. Differentiation of Multi-Lineage Progenitor Cells to Chondrocytes
US20090123436A1 (en) 2007-11-08 2009-05-14 Surmodics, Inc. Cryopreservative compositions and methods
WO2009129101A1 (en) 2008-04-14 2009-10-22 Advanced Technologies And Regenerative Medicine, Llc Liquid buffered gdf-5 formulations
WO2009131995A1 (en) 2008-04-21 2009-10-29 Nanobio Corporation Nanoemulsion influenza vaccine
US20110212127A1 (en) * 2008-09-24 2011-09-01 Stabilitech Ltd. Method for Preserving Polypeptides Using a Sugar and Polyethyleneimine
CN102164943A (zh) 2008-09-24 2011-08-24 稳定技术有限公司 使用糖和聚乙烯亚胺保存多肽的方法
WO2010146598A2 (en) 2008-11-07 2010-12-23 Serum Institute Of India Ltd. Stable, dried rotavirus vaccine, compositions and process for preparation thereof
WO2010132508A2 (en) 2009-05-11 2010-11-18 Biomatrica, Inc. Compositions and methods for biological sample storage
CN101670104A (zh) 2009-09-24 2010-03-17 浙江大学 一种含人参皂甙的油佐剂及其制备方法
US20130171128A1 (en) 2010-03-02 2013-07-04 Amgen Inc. Reducing viscosity of pharmaceutical formulations
HUE033656T2 (en) 2010-03-31 2017-12-28 Stabilitech Ltd Binders for stabilizing virus particles
EP2898890B1 (en) * 2010-03-31 2019-08-21 Stabilitech Biopharma Ltd Stabilisation of viral particles
HUE042330T2 (hu) 2010-03-31 2019-06-28 Stabilitech Biopharma Ltd Módszer alumínium adjuvánsok és alumíniummal adjuvált vakcinák megóvására
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
GB201406569D0 (en) * 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
MX2019008105A (es) 2017-01-06 2020-07-22 Stabilitech Biopharma Ltd Virus.
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Similar Documents

Publication Publication Date Title
JP2013523704A5 (OSRAM)
JP2013524782A5 (OSRAM)
RU2020123713A (ru) Жидкие вакцины на основе живых оболочечных вирусов
JP2008533007A5 (OSRAM)
JP2015537020A5 (OSRAM)
JP2013523677A5 (OSRAM)
RU2016119746A (ru) Стабильный состав инсулина глулизин
JP2018504420A5 (OSRAM)
JP2012051891A5 (OSRAM)
EA201492021A1 (ru) Антительный состав
JP2014129360A5 (OSRAM)
JP2011201907A5 (OSRAM)
JP2014521744A5 (OSRAM)
JP2016534153A5 (OSRAM)
MX378901B (es) Formulaciones liquidas estables de virus de vacuna.
JP2013543505A5 (OSRAM)
JP2014520852A5 (OSRAM)
JP2018500343A5 (OSRAM)
JP2015535243A5 (OSRAM)
JP2013523676A5 (OSRAM)
EA201390810A1 (ru) Жидкие вирусные составы
JP2015051983A5 (OSRAM)
JP2013537212A5 (OSRAM)
JP2019519570A5 (OSRAM)
RU2016111704A (ru) Производные дезоксинойиримицина и способы их применения