JP2014505704A5 - - Google Patents

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JP2014505704A5
JP2014505704A5 JP2013552625A JP2013552625A JP2014505704A5 JP 2014505704 A5 JP2014505704 A5 JP 2014505704A5 JP 2013552625 A JP2013552625 A JP 2013552625A JP 2013552625 A JP2013552625 A JP 2013552625A JP 2014505704 A5 JP2014505704 A5 JP 2014505704A5
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Japan
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composition
modified oligonucleotide
injury
modified
skin
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JP2013552625A
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JP2014505704A (ja
JP6177692B2 (ja
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Priority claimed from PCT/US2012/023620 external-priority patent/WO2012106508A1/en
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JP2013552625A 2011-02-02 2012-02-02 結合組織増殖因子(ctgf)をターゲティングするアンチセンス化合物を用いた、ケロイドまたは肥厚性瘢痕の治療法 Expired - Fee Related JP6177692B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161438879P 2011-02-02 2011-02-02
US61/438,879 2011-02-02
US201161488666P 2011-05-20 2011-05-20
US61/488,666 2011-05-20
US201161527821P 2011-08-26 2011-08-26
US61/527,821 2011-08-26
PCT/US2012/023620 WO2012106508A1 (en) 2011-02-02 2012-02-02 Method of treating keloids or hypertrophic scars using antisense compounds targeting connective tissue growth factor (ctgf)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017038688A Division JP2017137325A (ja) 2011-02-02 2017-03-01 結合組織増殖因子(ctgf)をターゲティングするアンチセンス化合物を用いた、ケロイドまたは肥厚性瘢痕の治療法

Publications (3)

Publication Number Publication Date
JP2014505704A JP2014505704A (ja) 2014-03-06
JP2014505704A5 true JP2014505704A5 (enExample) 2015-05-14
JP6177692B2 JP6177692B2 (ja) 2017-08-09

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013552625A Expired - Fee Related JP6177692B2 (ja) 2011-02-02 2012-02-02 結合組織増殖因子(ctgf)をターゲティングするアンチセンス化合物を用いた、ケロイドまたは肥厚性瘢痕の治療法
JP2017038688A Pending JP2017137325A (ja) 2011-02-02 2017-03-01 結合組織増殖因子(ctgf)をターゲティングするアンチセンス化合物を用いた、ケロイドまたは肥厚性瘢痕の治療法
JP2018100386A Withdrawn JP2018150351A (ja) 2011-02-02 2018-05-25 結合組織増殖因子(ctgf)をターゲティングするアンチセンス化合物を用いた、ケロイドまたは肥厚性瘢痕の治療法

Family Applications After (2)

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JP2017038688A Pending JP2017137325A (ja) 2011-02-02 2017-03-01 結合組織増殖因子(ctgf)をターゲティングするアンチセンス化合物を用いた、ケロイドまたは肥厚性瘢痕の治療法
JP2018100386A Withdrawn JP2018150351A (ja) 2011-02-02 2018-05-25 結合組織増殖因子(ctgf)をターゲティングするアンチセンス化合物を用いた、ケロイドまたは肥厚性瘢痕の治療法

Country Status (19)

Country Link
US (3) US9173894B2 (enExample)
EP (1) EP2670411B1 (enExample)
JP (3) JP6177692B2 (enExample)
KR (1) KR101697396B1 (enExample)
CN (1) CN103635197A (enExample)
AU (4) AU2012212110A1 (enExample)
BR (1) BR112013019803A2 (enExample)
CA (1) CA2825059A1 (enExample)
DK (1) DK2670411T3 (enExample)
ES (1) ES2729956T3 (enExample)
HU (1) HUE044178T4 (enExample)
IL (1) IL227714B (enExample)
MX (1) MX365647B (enExample)
PL (1) PL2670411T3 (enExample)
PT (1) PT2670411T (enExample)
RU (1) RU2608655C2 (enExample)
SI (1) SI2670411T1 (enExample)
TW (1) TWI593416B (enExample)
WO (1) WO2012106508A1 (enExample)

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CA2932753A1 (en) * 2013-12-04 2015-06-11 Rxi Pharmaceuticals Corporation Methods for treatment of wound healing utilizing chemically modified oligonucleotides
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KR102506169B1 (ko) 2014-09-05 2023-03-08 피오 파마슈티칼스 코프. Tyr 또는 mmp1을 표적화하는 핵산을 사용한 노화 및 피부 장애의 치료 방법
CN108251420B (zh) * 2016-12-28 2024-08-02 苏州瑞博生物技术股份有限公司 抑制人和动物中CTGF基因表达的siRNA、包含其的组合物及其应用
EP4282985A3 (en) * 2017-03-24 2024-02-28 Gen-Probe Incorporated Compositions and methods for detecting or quantifying parainfluenza virus
JP7167059B2 (ja) 2017-04-19 2022-11-08 フィオ ファーマシューティカルズ コーポレーション 核酸化合物の局所送達
EP3437650A1 (en) 2017-07-31 2019-02-06 Accanis Biotech F&E GmbH & Co KG Treatment of local skin hypotrophy conditions
KR102026138B1 (ko) 2017-08-02 2019-09-27 충남대학교산학협력단 Crif1 억제제를 함유하는 켈로이드 및 비후성 반흔 형성 억제 또는 치료용 조성물
CN112512532B (zh) * 2018-07-31 2024-11-08 雷莫内克斯生物制药有限公司 用于抑制ctgf表达的组合物
CN114375190A (zh) * 2019-05-08 2022-04-19 阿斯利康(瑞典)有限公司 用于皮肤和伤口的组合物及其使用方法
KR102100163B1 (ko) 2019-09-24 2020-04-13 테고사이언스 (주) 켈로이드 또는 비후성 반흔 예방 또는 치료용 조성물
KR102757180B1 (ko) * 2019-11-22 2025-01-21 (주)바이오니아 Ctgf 유전자 특이적 이중가닥 올리고뉴클레오티드 및 이를 포함하는 섬유증 관련 질환 및 호흡기 관련 질환 예방 및 치료용 조성물
CN110840894B (zh) * 2019-12-19 2020-06-02 温州医科大学附属第一医院 一种复合抗疤痕硅酮喷雾剂及其制备方法
CN111208223B (zh) * 2020-01-13 2023-01-17 浙江大学 心脏死亡后捐献受体术前预警移植肾延迟复功的代谢物
RU2731527C1 (ru) * 2020-01-28 2020-09-03 Кирилл Александрович Новиков Способ устранения рубцовых изменений кожи
CN114807127A (zh) * 2021-01-19 2022-07-29 陈璞 用于结缔组织生长因子的小干扰rna及其应用
CN115282262B (zh) * 2022-08-16 2024-07-12 四川大学华西医院 一种用于皮肤缺损治疗的组合物

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