RU2608655C2 - Способ лечения келоидов или гипертрофических рубцов с использованием антисмысловых соединений, направленно действующих на фактор роста соединительной ткани(CTGF) - Google Patents

Способ лечения келоидов или гипертрофических рубцов с использованием антисмысловых соединений, направленно действующих на фактор роста соединительной ткани(CTGF) Download PDF

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RU2608655C2
RU2608655C2 RU2013134403A RU2013134403A RU2608655C2 RU 2608655 C2 RU2608655 C2 RU 2608655C2 RU 2013134403 A RU2013134403 A RU 2013134403A RU 2013134403 A RU2013134403 A RU 2013134403A RU 2608655 C2 RU2608655 C2 RU 2608655C2
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modified oligonucleotide
modified
scar
formation
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RU2013134403A
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RU2013134403A (ru
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Николас М. Дин
Линкольн КРОЧМЭЛ
Грегори ХАРДИ
Дж. Гордон ФОУЛКЕС
Найалл О`ДОННЕЛЛ
Лерой ЯНГ
Марк ДЖЕУЭЛЛ
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Экскалиард Фармасьютикалс, Инк.
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RU2013134403A 2011-02-02 2012-02-02 Способ лечения келоидов или гипертрофических рубцов с использованием антисмысловых соединений, направленно действующих на фактор роста соединительной ткани(CTGF) RU2608655C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161438879P 2011-02-02 2011-02-02
US61/438,879 2011-02-02
US201161488666P 2011-05-20 2011-05-20
US61/488,666 2011-05-20
US201161527821P 2011-08-26 2011-08-26
US61/527,821 2011-08-26
PCT/US2012/023620 WO2012106508A1 (en) 2011-02-02 2012-02-02 Method of treating keloids or hypertrophic scars using antisense compounds targeting connective tissue growth factor (ctgf)

Publications (2)

Publication Number Publication Date
RU2013134403A RU2013134403A (ru) 2015-03-10
RU2608655C2 true RU2608655C2 (ru) 2017-01-23

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US (3) US9173894B2 (enExample)
EP (1) EP2670411B1 (enExample)
JP (3) JP6177692B2 (enExample)
KR (1) KR101697396B1 (enExample)
CN (1) CN103635197A (enExample)
AU (4) AU2012212110A1 (enExample)
BR (1) BR112013019803A2 (enExample)
CA (1) CA2825059A1 (enExample)
DK (1) DK2670411T3 (enExample)
ES (1) ES2729956T3 (enExample)
HU (1) HUE044178T4 (enExample)
IL (1) IL227714B (enExample)
MX (1) MX365647B (enExample)
PL (1) PL2670411T3 (enExample)
PT (1) PT2670411T (enExample)
RU (1) RU2608655C2 (enExample)
SI (1) SI2670411T1 (enExample)
TW (1) TWI593416B (enExample)
WO (1) WO2012106508A1 (enExample)

Cited By (1)

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RU2806104C1 (ru) * 2023-04-06 2023-10-26 Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) Способ выбора лечения келоидного рубца

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CN108251420B (zh) * 2016-12-28 2024-08-02 苏州瑞博生物技术股份有限公司 抑制人和动物中CTGF基因表达的siRNA、包含其的组合物及其应用
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EP3437650A1 (en) 2017-07-31 2019-02-06 Accanis Biotech F&E GmbH & Co KG Treatment of local skin hypotrophy conditions
KR102026138B1 (ko) 2017-08-02 2019-09-27 충남대학교산학협력단 Crif1 억제제를 함유하는 켈로이드 및 비후성 반흔 형성 억제 또는 치료용 조성물
KR20200014684A (ko) * 2018-07-31 2020-02-11 주식회사 레모넥스 Ctgf 발현 억제용 조성물
EP3965797A1 (en) * 2019-05-08 2022-03-16 AstraZeneca AB Compositions for skin and wounds and methods of use thereof
KR102100163B1 (ko) 2019-09-24 2020-04-13 테고사이언스 (주) 켈로이드 또는 비후성 반흔 예방 또는 치료용 조성물
KR102757180B1 (ko) * 2019-11-22 2025-01-21 (주)바이오니아 Ctgf 유전자 특이적 이중가닥 올리고뉴클레오티드 및 이를 포함하는 섬유증 관련 질환 및 호흡기 관련 질환 예방 및 치료용 조성물
CN110840894B (zh) * 2019-12-19 2020-06-02 温州医科大学附属第一医院 一种复合抗疤痕硅酮喷雾剂及其制备方法
CN111208223B (zh) * 2020-01-13 2023-01-17 浙江大学 心脏死亡后捐献受体术前预警移植肾延迟复功的代谢物
RU2731527C1 (ru) * 2020-01-28 2020-09-03 Кирилл Александрович Новиков Способ устранения рубцовых изменений кожи
CN114807127A (zh) * 2021-01-19 2022-07-29 陈璞 用于结缔组织生长因子的小干扰rna及其应用
CN115282262B (zh) * 2022-08-16 2024-07-12 四川大学华西医院 一种用于皮肤缺损治疗的组合物

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