JP2014218523A5 - - Google Patents
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- Publication number
- JP2014218523A5 JP2014218523A5 JP2014167814A JP2014167814A JP2014218523A5 JP 2014218523 A5 JP2014218523 A5 JP 2014218523A5 JP 2014167814 A JP2014167814 A JP 2014167814A JP 2014167814 A JP2014167814 A JP 2014167814A JP 2014218523 A5 JP2014218523 A5 JP 2014218523A5
- Authority
- JP
- Japan
- Prior art keywords
- orally disintegrating
- disintegrating tablet
- tablet according
- outer shell
- mass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000006191 orally-disintegrating tablet Substances 0.000 claims 16
- RYYCJUAHISIHTL-UHFFFAOYSA-N 5-azaorotic acid Chemical compound OC(=O)C1=NC(=O)NC(=O)N1 RYYCJUAHISIHTL-UHFFFAOYSA-N 0.000 claims 4
- ZPLQIPFOCGIIHV-UHFFFAOYSA-N Gimeracil Chemical compound OC1=CC(=O)C(Cl)=CN1 ZPLQIPFOCGIIHV-UHFFFAOYSA-N 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 4
- 229950009822 gimeracil Drugs 0.000 claims 4
- 229950000193 oteracil Drugs 0.000 claims 4
- 239000003826 tablet Substances 0.000 claims 4
- WFWLQNSHRPWKFK-ZCFIWIBFSA-N tegafur Chemical compound O=C1NC(=O)C(F)=CN1[C@@H]1OCCC1 WFWLQNSHRPWKFK-ZCFIWIBFSA-N 0.000 claims 4
- 229960001674 tegafur Drugs 0.000 claims 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 3
- 229920000881 Modified starch Polymers 0.000 claims 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 3
- 229960000913 crospovidone Drugs 0.000 claims 3
- 239000007884 disintegrant Substances 0.000 claims 3
- 239000008101 lactose Substances 0.000 claims 3
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 claims 3
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 claims 3
- 229920002678 cellulose Polymers 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 239000008358 core component Substances 0.000 claims 2
- 230000001186 cumulative effect Effects 0.000 claims 2
- 238000010998 test method Methods 0.000 claims 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 1
- 229920002261 Corn starch Polymers 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- VJHCJDRQFCCTHL-UHFFFAOYSA-N acetic acid 2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)=O.OCC(O)C(O)C(O)C(O)C=O VJHCJDRQFCCTHL-UHFFFAOYSA-N 0.000 claims 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 1
- 229950008138 carmellose Drugs 0.000 claims 1
- 239000008120 corn starch Substances 0.000 claims 1
- 229940099112 cornstarch Drugs 0.000 claims 1
- 238000012812 general test Methods 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000012360 testing method Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014167814A JP5769853B2 (ja) | 2011-05-25 | 2014-08-20 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011116884 | 2011-05-25 | ||
| JP2011116884 | 2011-05-25 | ||
| JP2014167814A JP5769853B2 (ja) | 2011-05-25 | 2014-08-20 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013516428A Division JP5689173B2 (ja) | 2011-05-25 | 2012-05-24 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014218523A JP2014218523A (ja) | 2014-11-20 |
| JP2014218523A5 true JP2014218523A5 (https=) | 2015-04-09 |
| JP5769853B2 JP5769853B2 (ja) | 2015-08-26 |
Family
ID=47217314
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013516428A Active JP5689173B2 (ja) | 2011-05-25 | 2012-05-24 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
| JP2014167814A Active JP5769853B2 (ja) | 2011-05-25 | 2014-08-20 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013516428A Active JP5689173B2 (ja) | 2011-05-25 | 2012-05-24 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20140335174A1 (https=) |
| EP (1) | EP2716290B1 (https=) |
| JP (2) | JP5689173B2 (https=) |
| KR (2) | KR101869127B1 (https=) |
| AU (1) | AU2012259803B2 (https=) |
| BR (1) | BR112013030093B1 (https=) |
| CA (1) | CA2836865C (https=) |
| ES (1) | ES2671926T3 (https=) |
| IL (1) | IL229372B (https=) |
| MX (1) | MX353289B (https=) |
| MY (1) | MY167883A (https=) |
| PH (1) | PH12013502323A1 (https=) |
| RU (1) | RU2601620C2 (https=) |
| SG (2) | SG194922A1 (https=) |
| TW (2) | TWI566787B (https=) |
| WO (1) | WO2012161240A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012161240A1 (ja) * | 2011-05-25 | 2012-11-29 | 大鵬薬品工業株式会社 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
| CN107837273A (zh) * | 2016-09-18 | 2018-03-27 | 江苏金甙生物技术有限公司 | 一种肠溶替吉奥缓释制剂及其制备方法 |
| CN107865871B (zh) * | 2016-09-23 | 2021-09-03 | 江苏恒瑞医药股份有限公司 | 一种替吉奥组合物及其制备方法 |
| CN106619689B (zh) * | 2016-12-30 | 2018-05-01 | 陈晓华 | 一种用于治疗癌症的药物组合物、试剂盒及其应用 |
| EP4029380B1 (en) * | 2019-09-13 | 2026-01-28 | Meiji Co., Ltd | Solid milk |
| JPWO2023238929A1 (https=) * | 2022-06-10 | 2023-12-14 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992021345A1 (en) | 1991-05-27 | 1992-12-10 | Taiho Pharmaceutical Co., Ltd. | Composition, method and kit for potentiating antitumor activity and for curing tumor |
| CA2322315C (en) * | 1998-03-06 | 2008-09-16 | Eurand International S.P.A. | Fast disintegrating tablets |
| CA2408956C (en) * | 2000-05-18 | 2011-07-12 | Therics, Inc. | Method and form of a drug delivery device,such as encapsulating a toxic core within a non-toxic region in an oral dosage form |
| US20050202082A1 (en) * | 2001-09-28 | 2005-09-15 | Tsuneyuki Hibino | Press-coated molded article undergoing quick disintegration |
| JP2005512997A (ja) * | 2001-11-07 | 2005-05-12 | シントン・ベスローテン・フェンノートシャップ | タムスロシン錠 |
| US6723348B2 (en) * | 2001-11-16 | 2004-04-20 | Ethypharm | Orodispersible tablets containing fexofenadine |
| WO2003080023A2 (en) * | 2002-03-20 | 2003-10-02 | Elan Pharma International Limited | Fast dissolving dosage forms having reduced friability |
| JP4610481B2 (ja) * | 2003-03-14 | 2011-01-12 | 大鵬薬品工業株式会社 | 抗腫瘍効果増強剤及び抗腫瘍剤 |
| CA2540488A1 (en) * | 2003-09-29 | 2005-04-07 | Cipla Limited | Pharmaceutical formulation with improved stability |
| CN100333726C (zh) | 2004-12-23 | 2007-08-29 | 鲁南制药集团股份有限公司 | 含有替加氟、吉莫斯特和氧嗪酸钾的口腔崩解片 |
| DE602006016576D1 (de) * | 2005-04-01 | 2010-10-14 | Taiho Pharmaceutical Co Ltd | Strahlentherapieverstärker |
| JP4994618B2 (ja) * | 2005-08-11 | 2012-08-08 | 学校法人北里研究所 | Ｔｓ−１／カンプトテシン類による化学放射線療法 |
| MY151207A (en) * | 2007-12-27 | 2014-04-30 | Taiho Pharmaceutical Co Ltd | Oral particulate antitumor preparation |
| TWI468188B (zh) * | 2008-01-30 | 2015-01-11 | Univ Tokushima | Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation |
| KR100934876B1 (ko) | 2008-01-31 | 2010-01-06 | 성균관대학교산학협력단 | Ｌｉｇａ공정의 도금방법 |
| CN101380327B (zh) * | 2008-10-09 | 2011-01-26 | 北京恒瑞康达医药科技发展有限公司 | 抗癌复合缓释组合物及制备 |
| JP5553522B2 (ja) | 2009-03-31 | 2014-07-16 | 大鵬薬品工業株式会社 | 経口投与用医薬組成物 |
| EP2431032A4 (en) * | 2009-05-12 | 2012-11-07 | Taiho Pharmaceutical Co Ltd | ANTICROBIAL AGENTS WITH A TEGAFUR GIMERACIL OTERACIL CALIUM COMBINATION AND OXALIPLATIN |
| CN101711765B (zh) * | 2009-10-31 | 2011-03-23 | 山东新时代药业有限公司 | 一种含有替加氟、吉美嘧啶和奥替拉西钾的分散片 |
| WO2012161240A1 (ja) * | 2011-05-25 | 2012-11-29 | 大鵬薬品工業株式会社 | テガフール、ギメラシル、オテラシルカリウム含有有核錠 |
| CN102614183B (zh) * | 2012-03-05 | 2013-10-30 | 齐鲁制药(海南)有限公司 | 一种替吉奥的口服制剂 |
-
2012
- 2012-05-24 WO PCT/JP2012/063260 patent/WO2012161240A1/ja not_active Ceased
- 2012-05-24 KR KR1020137033946A patent/KR101869127B1/ko not_active Expired - Fee Related
- 2012-05-24 MY MYPI2013702158A patent/MY167883A/en unknown
- 2012-05-24 US US14/118,952 patent/US20140335174A1/en not_active Abandoned
- 2012-05-24 JP JP2013516428A patent/JP5689173B2/ja active Active
- 2012-05-24 CA CA2836865A patent/CA2836865C/en not_active Expired - Fee Related
- 2012-05-24 MX MX2013013563A patent/MX353289B/es active IP Right Grant
- 2012-05-24 BR BR112013030093A patent/BR112013030093B1/pt not_active IP Right Cessation
- 2012-05-24 RU RU2013157528/15A patent/RU2601620C2/ru active
- 2012-05-24 SG SG2013083829A patent/SG194922A1/en unknown
- 2012-05-24 EP EP12789023.4A patent/EP2716290B1/en not_active Not-in-force
- 2012-05-24 SG SG10201505503WA patent/SG10201505503WA/en unknown
- 2012-05-24 KR KR1020177016653A patent/KR20170072959A/ko not_active Ceased
- 2012-05-24 TW TW104113084A patent/TWI566787B/zh not_active IP Right Cessation
- 2012-05-24 ES ES12789023.4T patent/ES2671926T3/es active Active
- 2012-05-24 TW TW101118538A patent/TWI488659B/zh not_active IP Right Cessation
- 2012-05-24 AU AU2012259803A patent/AU2012259803B2/en not_active Ceased
- 2012-05-24 PH PH1/2013/502323A patent/PH12013502323A1/en unknown
-
2013
- 2013-11-11 IL IL229372A patent/IL229372B/en active IP Right Grant
-
2014
- 2014-08-20 JP JP2014167814A patent/JP5769853B2/ja active Active
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