JP2014015483A5 - - Google Patents

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Publication number
JP2014015483A5
JP2014015483A5 JP2013219880A JP2013219880A JP2014015483A5 JP 2014015483 A5 JP2014015483 A5 JP 2014015483A5 JP 2013219880 A JP2013219880 A JP 2013219880A JP 2013219880 A JP2013219880 A JP 2013219880A JP 2014015483 A5 JP2014015483 A5 JP 2014015483A5
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JP
Japan
Prior art keywords
compound
formula
compound according
complex
triethylenediamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013219880A
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English (en)
Japanese (ja)
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JP6148594B2 (ja
JP2014015483A (ja
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Publication date
Application filed filed Critical
Publication of JP2014015483A publication Critical patent/JP2014015483A/ja
Publication of JP2014015483A5 publication Critical patent/JP2014015483A5/ja
Application granted granted Critical
Publication of JP6148594B2 publication Critical patent/JP6148594B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013219880A 2007-08-02 2013-10-23 Ｅ１活性化酵素阻害剤の合成のためのプロセス Expired - Fee Related JP6148594B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US96300807P 2007-08-02 2007-08-02
US60/963,008 2007-08-02
US6237808P 2008-01-25 2008-01-25
US61/062,378 2008-01-25

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2010519947A Division JP5479336B2 (ja) 2007-08-02 2008-08-01 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014215250A Division JP2015025009A (ja) 2007-08-02 2014-10-22 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Publications (3)

Publication Number Publication Date
JP2014015483A JP2014015483A (ja) 2014-01-30
JP2014015483A5 true JP2014015483A5 (enExample) 2014-12-04
JP6148594B2 JP6148594B2 (ja) 2017-06-14

Family

ID=40225413

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010519947A Expired - Fee Related JP5479336B2 (ja) 2007-08-02 2008-08-01 Ｅ１活性化酵素阻害剤の合成のためのプロセス
JP2013219880A Expired - Fee Related JP6148594B2 (ja) 2007-08-02 2013-10-23 Ｅ１活性化酵素阻害剤の合成のためのプロセス
JP2014215250A Pending JP2015025009A (ja) 2007-08-02 2014-10-22 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2010519947A Expired - Fee Related JP5479336B2 (ja) 2007-08-02 2008-08-01 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014215250A Pending JP2015025009A (ja) 2007-08-02 2014-10-22 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Country Status (14)

Country Link
US (3) US8933225B2 (enExample)
EP (4) EP2178880B1 (enExample)
JP (3) JP5479336B2 (enExample)
KR (2) KR101925902B1 (enExample)
CN (3) CN101868461B (enExample)
AU (1) AU2008305767B2 (enExample)
CA (2) CA2695193C (enExample)
ES (4) ES2655028T3 (enExample)
IL (2) IL203590A (enExample)
MX (1) MX2010001126A (enExample)
RU (2) RU2015108944A (enExample)
TW (2) TWI426077B (enExample)
WO (1) WO2009042013A1 (enExample)
ZA (1) ZA201000482B (enExample)

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KR101925902B1 (ko) 2007-08-02 2018-12-06 밀레니엄 파머슈티컬스 인코퍼레이티드 Ｅ1 활성화 효소 억제제의 합성 방법
SG10201402148SA (en) 2009-05-14 2014-07-30 Millennium Pharm Inc Hydrochloride salt of ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo [2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate
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EP3173413B1 (en) 2012-02-17 2019-05-01 Millennium Pharmaceuticals, Inc. Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme
CN104072381B (zh) * 2013-03-26 2017-04-12 安徽贝克联合制药有限公司 光学纯氨基醇盐酸盐的制备方法
JP6556701B2 (ja) 2013-05-14 2019-08-07 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． Ｎｅｄｄ８活性化酵素阻害剤及び化学療法剤の投与
EP3901159A1 (en) 2014-07-01 2021-10-27 Millennium Pharmaceuticals, Inc. Heteroaryl compounds useful as inhibitors of sumo activating enzyme
TW201628621A (zh) 2014-10-29 2016-08-16 千禧製藥公司 泛素活化酶抑制劑及輻射之施用
CN104974051A (zh) * 2015-06-30 2015-10-14 苏州开元民生科技股份有限公司 (1S,4R)-cis-4-氨基-2-环戊烯-1-甲醇盐酸盐的合成方法
CN106854208B (zh) * 2016-11-25 2019-04-09 成都柏睿泰生物科技有限公司 肿瘤抑制剂mln4924的合成方法
WO2019060536A1 (en) 2017-09-21 2019-03-28 Millennium Pharmaceuticals, Inc. CO-CRYSTALLINE FORMS OF ((1S, 2S, 4R) -4- {4 - [(1S) -2,3-DIHYDRO-1H-INDEN-1-YLAMINO] -7H-PYRROLO [2,3-D] PYRIMIDIN -7-YL} -2-HYDROXYCYCLOPENTYL) METHYLSULFAMATE, THEIR FORMULATIONS AND USES
KR102018341B1 (ko) * 2018-06-21 2019-09-04 성균관대학교산학협력단 RNF170 및 pUL50을 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물
CN114072407A (zh) 2019-04-02 2022-02-18 阿里戈斯治疗公司 靶向prmt5的化合物
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US20240368165A1 (en) 2020-11-25 2024-11-07 Takeda Pharmaceutical Company Limited Solid state forms of hydrochloride salt of ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate

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KR101925902B1 (ko) 2007-08-02 2018-12-06 밀레니엄 파머슈티컬스 인코퍼레이티드 Ｅ1 활성화 효소 억제제의 합성 방법
SG10201402148SA (en) * 2009-05-14 2014-07-30 Millennium Pharm Inc Hydrochloride salt of ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo [2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate

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