JP2014015483A5 - - Google Patents

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Publication number
JP2014015483A5
JP2014015483A5 JP2013219880A JP2013219880A JP2014015483A5 JP 2014015483 A5 JP2014015483 A5 JP 2014015483A5 JP 2013219880 A JP2013219880 A JP 2013219880A JP 2013219880 A JP2013219880 A JP 2013219880A JP 2014015483 A5 JP2014015483 A5 JP 2014015483A5
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JP
Japan
Prior art keywords
compound
formula
compound according
complex
triethylenediamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013219880A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014015483A (ja
JP6148594B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2014015483A publication Critical patent/JP2014015483A/ja
Publication of JP2014015483A5 publication Critical patent/JP2014015483A5/ja
Application granted granted Critical
Publication of JP6148594B2 publication Critical patent/JP6148594B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013219880A 2007-08-02 2013-10-23 Ｅ１活性化酵素阻害剤の合成のためのプロセス Expired - Fee Related JP6148594B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US96300807P 2007-08-02 2007-08-02
US60/963,008 2007-08-02
US6237808P 2008-01-25 2008-01-25
US61/062,378 2008-01-25

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2010519947A Division JP5479336B2 (ja) 2007-08-02 2008-08-01 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014215250A Division JP2015025009A (ja) 2007-08-02 2014-10-22 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Publications (3)

Publication Number Publication Date
JP2014015483A JP2014015483A (ja) 2014-01-30
JP2014015483A5 true JP2014015483A5 (enExample) 2014-12-04
JP6148594B2 JP6148594B2 (ja) 2017-06-14

Family

ID=40225413

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010519947A Expired - Fee Related JP5479336B2 (ja) 2007-08-02 2008-08-01 Ｅ１活性化酵素阻害剤の合成のためのプロセス
JP2013219880A Expired - Fee Related JP6148594B2 (ja) 2007-08-02 2013-10-23 Ｅ１活性化酵素阻害剤の合成のためのプロセス
JP2014215250A Pending JP2015025009A (ja) 2007-08-02 2014-10-22 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2010519947A Expired - Fee Related JP5479336B2 (ja) 2007-08-02 2008-08-01 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014215250A Pending JP2015025009A (ja) 2007-08-02 2014-10-22 Ｅ１活性化酵素阻害剤の合成のためのプロセス

Country Status (14)

Country Link
US (3) US8933225B2 (enExample)
EP (4) EP2540727B1 (enExample)
JP (3) JP5479336B2 (enExample)
KR (2) KR101925902B1 (enExample)
CN (3) CN103483342B (enExample)
AU (1) AU2008305767B2 (enExample)
CA (2) CA2695193C (enExample)
ES (4) ES2757928T3 (enExample)
IL (2) IL203590A (enExample)
MX (1) MX2010001126A (enExample)
RU (2) RU2015108944A (enExample)
TW (2) TWI426077B (enExample)
WO (1) WO2009042013A1 (enExample)
ZA (1) ZA201000482B (enExample)

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EP2540727B1 (en) 2007-08-02 2018-07-25 Millennium Pharmaceuticals, Inc. Sulfamoylating reagent
EP2430026A1 (en) 2009-05-14 2012-03-21 Millennium Pharmaceuticals, Inc. Hydrochloride salt of ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo [2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate
JP2013541587A (ja) * 2010-11-05 2013-11-14 ミレニアム ファーマシューティカルズ， インコーポレイテッド Ｎｅｄｄ８活性化酵素阻害剤の投与
UA116534C2 (uk) * 2012-02-17 2018-04-10 Мілленніум Фармасьютікалз, Інк. Піразолопіримідинілові інгібітори убіквітинактивуючого ферменту
CN104072381B (zh) * 2013-03-26 2017-04-12 安徽贝克联合制药有限公司 光学纯氨基醇盐酸盐的制备方法
CN105407973A (zh) 2013-05-14 2016-03-16 米伦纽姆医药公司 Nedd8活化酶抑制剂及化学治疗剂的投与
BR112016030787B1 (pt) 2014-07-01 2022-12-20 Takeda Pharmaceutical Company Limited Entidade química, composição farmacêutica e seu uso
WO2016069393A1 (en) 2014-10-29 2016-05-06 Millennium Pharmaceuticals, Inc. Administration of ubiquitin-activating enzyme inhibitor and radiation
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CN106854208B (zh) * 2016-11-25 2019-04-09 成都柏睿泰生物科技有限公司 肿瘤抑制剂mln4924的合成方法
JP2020534331A (ja) 2017-09-21 2020-11-26 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． （（１ｓ，２ｓ，４ｒ）−４−｛４−［（１ｓ）−２，３−ジヒドロ−１ｈ−インデン−１−イルアミノ］−７ｈ−ピロロ［２，３−ｄ］ピリミジン−７−イル｝−２−ヒドロキシシクロペンチル）メチルスルファメートの共結晶形態、その製剤及び使用
KR102018341B1 (ko) * 2018-06-21 2019-09-04 성균관대학교산학협력단 RNF170 및 pUL50을 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물
JP2022522534A (ja) 2019-04-02 2022-04-19 アリゴス セラピューティクス インコーポレイテッド Ｐｒｍｔ５を標的にする化合物
WO2021241191A1 (ja) * 2020-05-26 2021-12-02 ソニーセミコンダクタソリューションズ株式会社 測距装置
WO2022112951A1 (en) 2020-11-25 2022-06-02 Takeda Pharmaceutical Company Limited Solid state forms of hydrochloride salt of ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate

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EP2540727B1 (en) 2007-08-02 2018-07-25 Millennium Pharmaceuticals, Inc. Sulfamoylating reagent
EP2430026A1 (en) 2009-05-14 2012-03-21 Millennium Pharmaceuticals, Inc. Hydrochloride salt of ((1s,2s,4r)-4-{4-[(1s)-2,3-dihydro-1h-inden-1-ylamino]-7h-pyrrolo [2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate

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