JP2013544494A5 - - Google Patents

Download PDF

Info

Publication number
JP2013544494A5
JP2013544494A5 JP2013527595A JP2013527595A JP2013544494A5 JP 2013544494 A5 JP2013544494 A5 JP 2013544494A5 JP 2013527595 A JP2013527595 A JP 2013527595A JP 2013527595 A JP2013527595 A JP 2013527595A JP 2013544494 A5 JP2013544494 A5 JP 2013544494A5
Authority
JP
Japan
Prior art keywords
seq
cells
ion channel
retinal
photoinduced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013527595A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013544494A (ja
JP5933556B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2011/065510 external-priority patent/WO2012032103A1/en
Publication of JP2013544494A publication Critical patent/JP2013544494A/ja
Publication of JP2013544494A5 publication Critical patent/JP2013544494A5/ja
Application granted granted Critical
Publication of JP5933556B2 publication Critical patent/JP5933556B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013527595A 2010-09-08 2011-09-08 変異チャネルロドプシン2 Active JP5933556B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38079310P 2010-09-08 2010-09-08
EP10175832 2010-09-08
EP10175832.4 2010-09-08
US61/380,793 2010-09-08
PCT/EP2011/065510 WO2012032103A1 (en) 2010-09-08 2011-09-08 Mutant channelrhodopsin 2

Publications (3)

Publication Number Publication Date
JP2013544494A JP2013544494A (ja) 2013-12-19
JP2013544494A5 true JP2013544494A5 (https=) 2014-10-02
JP5933556B2 JP5933556B2 (ja) 2016-06-15

Family

ID=42979822

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013527595A Active JP5933556B2 (ja) 2010-09-08 2011-09-08 変異チャネルロドプシン2

Country Status (20)

Country Link
US (1) US8748578B2 (https=)
EP (1) EP2614079B1 (https=)
JP (1) JP5933556B2 (https=)
KR (1) KR101945962B1 (https=)
CN (1) CN103261219B (https=)
AU (1) AU2011298745B2 (https=)
BR (1) BR112013005634A2 (https=)
CA (1) CA2810757C (https=)
DK (1) DK2614079T3 (https=)
ES (1) ES2545992T3 (https=)
HR (1) HRP20150846T1 (https=)
HU (1) HUE025952T2 (https=)
IL (1) IL225060A (https=)
MX (1) MX347453B (https=)
PL (1) PL2614079T3 (https=)
PT (1) PT2614079E (https=)
RU (1) RU2595384C2 (https=)
SG (1) SG188409A1 (https=)
SI (1) SI2614079T1 (https=)
WO (1) WO2012032103A1 (https=)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9238150B2 (en) 2005-07-22 2016-01-19 The Board Of Trustees Of The Leland Stanford Junior University Optical tissue interface method and apparatus for stimulating cells
US9274099B2 (en) 2005-07-22 2016-03-01 The Board Of Trustees Of The Leland Stanford Junior University Screening test drugs to identify their effects on cell membrane voltage-gated ion channel
US8926959B2 (en) 2005-07-22 2015-01-06 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
EP1919497B1 (en) 2005-07-22 2020-02-12 The Board of Trustees of the Leland Stanford Junior University Light-activated cation channel and uses thereof
US10052497B2 (en) 2005-07-22 2018-08-21 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
EP2019588A4 (en) 2006-05-04 2010-11-24 Univ Wayne State RESTORATION OF VISUAL RESPONSES BY IN VIVO ADMINISTRATION OF NUCLEIC ACIDS OF RHODOPSIN
WO2008086470A1 (en) 2007-01-10 2008-07-17 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
WO2008101128A1 (en) 2007-02-14 2008-08-21 The Board Of Trustees Of The Leland Stanford Junior University System, method and applications involving identification of biological circuits such as neurological characteristics
WO2008106694A2 (en) 2007-03-01 2008-09-04 The Board Of Trustees Of The Leland Stanford Junior University Systems, methods and compositions for optical stimulation of target cells
US10434327B2 (en) 2007-10-31 2019-10-08 The Board Of Trustees Of The Leland Stanford Junior University Implantable optical stimulators
US10035027B2 (en) 2007-10-31 2018-07-31 The Board Of Trustees Of The Leland Stanford Junior University Device and method for ultrasonic neuromodulation via stereotactic frame based technique
MY169771A (en) 2008-04-23 2019-05-15 Univ Leland Stanford Junior Systems, methods and compositions for optical stimulation of target cells
WO2009148946A2 (en) 2008-05-29 2009-12-10 The Board Of Trustees Of The Leland Stanford Junior University Cell line, system and method for optical control of secondary messengers
JP2011525130A (ja) 2008-06-17 2011-09-15 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ 光伝送素子を用いた標的細胞の光刺激のための方法、システム、および装置
EP2303405A4 (en) 2008-06-17 2017-12-27 The Board of Trustees of the Leland Stanford Junior University Apparatus and methods for controlling cellular development
WO2010006049A1 (en) 2008-07-08 2010-01-14 The Board Of Trustees Of The Leland Stanford Junior University Materials and approaches for optical stimulation of the peripheral nervous system
NZ602416A (en) 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto
WO2011116238A2 (en) 2010-03-17 2011-09-22 The Board Of Trustees Of The Leland Stanford Junior University. Light-sensitive ion-passing molecules
WO2011140279A1 (en) 2010-05-04 2011-11-10 Wayne State University Aav-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
CN106376525A (zh) 2010-11-05 2017-02-08 斯坦福大学托管董事会 记忆功能的控制和表征
CN106422081B (zh) 2010-11-05 2019-06-21 斯坦福大学托管董事会 用于光遗传学方法的光的上转换
AU2011323235B2 (en) 2010-11-05 2015-10-29 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic control of reward-related behaviors
ES2684307T3 (es) * 2010-11-05 2018-10-02 The Board Of Trustees Of The Leland Stanford Junior University Proteínas estabilizadas de tipo opsina de función escalonada y métodos de uso de las mismas
CN106106368A (zh) 2010-11-05 2016-11-16 斯坦福大学托管董事会 光控cns功能障碍
WO2012061679A2 (en) 2010-11-05 2012-05-10 The Board Of Trustees Of The Leland Stanford Junior University Light-activated chimeric opsins and methods of using the same
US8696722B2 (en) 2010-11-22 2014-04-15 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic magnetic resonance imaging
CA2859364C (en) 2011-12-16 2019-05-07 The Board Of Trustees Of The Leland Stanford Junior University Opsin polypeptides and methods of use thereof
EP3205374B1 (en) 2012-02-21 2019-03-27 The Board of Trustees of The Leland Stanford Junior University Compositions for treating neurogenic disorders of the pelvic floor
AU2013230112A1 (en) 2012-03-05 2014-09-25 Wayne State University Identification of channelrhodopsin-2 (Chop2) mutations and methods of use
US9636380B2 (en) 2013-03-15 2017-05-02 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic control of inputs to the ventral tegmental area
JP6594854B2 (ja) 2013-03-15 2019-10-23 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 行動状態の光遺伝学的制御方法
AU2014260101B2 (en) 2013-04-29 2018-07-26 Humboldt-Universitat Zu Berlin Devices, systems and methods for optogenetic modulation of action potentials in target cells
EP3033427A4 (en) 2013-08-14 2017-05-31 The Board Of Trustees Of The University Of the Leland Stanford Junior University Compositions and methods for controlling pain
JP6118239B2 (ja) 2013-11-29 2017-04-19 雅敏 堀 害虫の防除方法及び防除装置
US10392426B2 (en) 2014-02-07 2019-08-27 Massachusetts Institute Of Technology Blue-light-activated ion channel polypeptides and uses thereof
WO2015142984A1 (en) * 2014-03-18 2015-09-24 Washington University Methods and compositions for red-shifted chromophore substitution for optogenetic applications
WO2015161308A1 (en) * 2014-04-18 2015-10-22 Massachusetts Institute Of Technology Mutant channelrhodopsins with altered ion selectivity
WO2016209654A1 (en) 2015-06-22 2016-12-29 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for imaging and/or optogenetic control of light-responsive neurons
EP3464342B1 (en) * 2016-06-03 2026-03-18 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Mutant light-inducible ion channel of chrimson
WO2017207745A1 (en) 2016-06-03 2017-12-07 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Mutant light-inducible ion channel of channelrhodopsin
CA3034887A1 (en) 2016-08-29 2018-03-08 Wayne State University Identification of mutations in channelopsin variants having improved light sensitivity and methods of use thereof
WO2018106369A2 (en) 2016-11-06 2018-06-14 Nanoscope Technologies Llc Optogenetic modulation by multi-characteristic opsins for vision restoration and other applications thereof
US11294165B2 (en) 2017-03-30 2022-04-05 The Board Of Trustees Of The Leland Stanford Junior University Modular, electro-optical device for increasing the imaging field of view using time-sequential capture
EP3609518A1 (en) * 2017-04-12 2020-02-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. New optogenetic tool
CN110483645B (zh) * 2018-05-14 2023-05-12 郑州大学第一附属医院 线粒体定位质子泵型视紫红质、其突变蛋白及其应用
US11313860B2 (en) 2018-07-26 2022-04-26 Council Of Scientific & Industrial Research Screening kit for detection of grades of cervical cancer and process for the preparation thereof
CN112689675B (zh) * 2018-09-14 2023-09-19 国立大学法人名古屋工业大学 光响应性蛋白及其应用
US20230104240A1 (en) * 2020-03-13 2023-04-06 Nagoya Institute Of Technology Photoresponsive protein for color recognition and use thereof
WO2022176754A1 (ja) * 2021-02-18 2022-08-25 国立大学法人名古屋工業大学 青色光もしくは藍色光応答性タンパク質及びその利用
EP4223768A1 (en) 2022-02-04 2023-08-09 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Novel mutant bacteriorhodopsin-like-channelrhodopsin ion channel
WO2024092248A1 (en) * 2022-10-28 2024-05-02 The Board Of Trustees Of The Leland Stanford Junior University Enhanced light gated potassium selective channelrhodopsin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2112501A1 (de) 1998-02-05 2009-10-28 Novartis Ag Verfahren und Vorrichtung zur Lumineszenzmessung
DE10216005A1 (de) * 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
EP2019588A4 (en) * 2006-05-04 2010-11-24 Univ Wayne State RESTORATION OF VISUAL RESPONSES BY IN VIVO ADMINISTRATION OF NUCLEIC ACIDS OF RHODOPSIN
DE102008020152B4 (de) * 2008-04-22 2012-04-05 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
NZ602416A (en) * 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto

Similar Documents

Publication Publication Date Title
JP2013544494A5 (https=)
RU2013115454A (ru) Мутантный канальный родопсин-2
Hein et al. OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential
HK1244695A1 (zh) Hpv颗粒及其用途
JP2022513558A (ja) 広域スペクトルな抗インフルエンザワクチン免疫原及びその使用
CN103534353B (zh) 修饰型氨基转移酶、其基因以及利用它们的光学活性氨基化合物的制造方法
JP2015510759A5 (https=)
CN1350578A (zh) 用于疫苗和基因治疗的重组流感病毒
JP2016509864A5 (https=)
WO2020069339A1 (en) Mutant reverse tetracycline transactivators for expression of genes
JP2016513457A5 (https=)
CN104073513B (zh) 甲型流感病毒疫苗哺乳动物细胞适应株的获得方法和适应位点
CN113462630A (zh) 一种高产d-泛酸基因工程菌及其构建与应用
JP2014530609A5 (https=)
JP2019526270A5 (https=)
CN113462669A (zh) 酮泛解酸羟甲基转移酶突变体、编码基因及其应用
CA2804121C (fr) Souches virales modifiees et procede pour ameliorer la production de semences vaccinales de virus influenza
Takeuchi et al. Photostable abscisic acid agonists with a geometrically rigid cyclized side chain
AU2017391000A1 (en) Gene involved in synthesis of cyclic peptide compound, method for producing cyclic peptide compound using the same, and transformant comprising the same
RU2354695C1 (ru) Аттенуированный холодоадаптированный штамм вируса гриппа а/краснодар/101/59/35 (h2n2) для получения штаммов живой интраназальной гриппозной вакцины
Wen et al. Efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the classical swine H1N1 subtype influenza virus in mice and pigs
Zak et al. Enhancing the yield and quality of influenza virus-like particles (VLPs) produced in insect cells by inhibiting cytopathic effects of matrix protein M2
JP2012183048A (ja) 4−ヒドロキシ安息香酸関連物質の製造法
WO2020014675A1 (en) Methods for generating pan-epitopic immunogens of influenza h3 virus, compositions and methods of use thereof
JPWO2015156369A1 (ja) 変異酵素及び前記変異酵素を用いたテルペノイドの製造方法