JP2013540776A5 - - Google Patents
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- Publication number
- JP2013540776A5 JP2013540776A5 JP2013533942A JP2013533942A JP2013540776A5 JP 2013540776 A5 JP2013540776 A5 JP 2013540776A5 JP 2013533942 A JP2013533942 A JP 2013533942A JP 2013533942 A JP2013533942 A JP 2013533942A JP 2013540776 A5 JP2013540776 A5 JP 2013540776A5
- Authority
- JP
- Japan
- Prior art keywords
- cyclosporin
- sar
- chr
- compound
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39244910P | 2010-10-12 | 2010-10-12 | |
| US61/392,449 | 2010-10-12 | ||
| PCT/US2011/055791 WO2012051194A1 (en) | 2010-10-12 | 2011-10-11 | Cyclosporin analogs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015173082A Division JP6250608B2 (ja) | 2010-10-12 | 2015-09-02 | シクロスポリンアナログ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013540776A JP2013540776A (ja) | 2013-11-07 |
| JP2013540776A5 true JP2013540776A5 (enExample) | 2013-12-26 |
| JP5805774B2 JP5805774B2 (ja) | 2015-11-10 |
Family
ID=44883784
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013533942A Expired - Fee Related JP5805774B2 (ja) | 2010-10-12 | 2011-10-11 | シクロスポリンアナログ |
| JP2015173082A Expired - Fee Related JP6250608B2 (ja) | 2010-10-12 | 2015-09-02 | シクロスポリンアナログ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015173082A Expired - Fee Related JP6250608B2 (ja) | 2010-10-12 | 2015-09-02 | シクロスポリンアナログ |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20120088734A1 (enExample) |
| EP (1) | EP2627664B1 (enExample) |
| JP (2) | JP5805774B2 (enExample) |
| KR (1) | KR20140026329A (enExample) |
| CN (1) | CN103328497A (enExample) |
| AU (1) | AU2011316690C1 (enExample) |
| BR (1) | BR112013008864A2 (enExample) |
| CA (1) | CA2814192A1 (enExample) |
| IL (1) | IL225617A0 (enExample) |
| MX (1) | MX2013004061A (enExample) |
| RU (1) | RU2013119869A (enExample) |
| SG (1) | SG189880A1 (enExample) |
| WO (1) | WO2012051194A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012021796A2 (en) | 2010-08-12 | 2012-02-16 | S&T Global, Inc. | Novel cyclosporin derivatives for the treatment and prevention of a viral infection |
| MX2013004062A (es) | 2010-10-12 | 2013-07-22 | Allergan Inc | Analogos de ciclosporina. |
| RU2013119869A (ru) * | 2010-10-12 | 2014-11-20 | Аллерган, Инк. | Аналоги циклоспорина |
| US9890198B2 (en) | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
| LT2651965T (lt) * | 2010-12-15 | 2019-01-10 | Contravir Pharmaceuticals, Inc. | Ciklosporino analogo molekulės su modifikuotomis 1 ir 3 aminorūgštimis |
| CA2874548A1 (en) * | 2012-06-01 | 2013-12-05 | Allergan, Inc. | Cyclosporin a analogs |
| GB201222455D0 (en) * | 2012-12-13 | 2013-01-30 | Perioc Ltd | Novel pharmaceutical formulations and their use in the treatment of periodontaldisease |
| EP2964269A1 (en) | 2013-03-08 | 2016-01-13 | Allergan, Inc. | Cyclosporine a-steroid conjugates |
| WO2016112321A1 (en) | 2015-01-08 | 2016-07-14 | Allergan, Inc. | Cyclosporin derivatives wherein the mebmt sidechain has been cyclized |
| US10077289B2 (en) | 2015-03-31 | 2018-09-18 | Allergan, Inc. | Cyclosporins modified on the MeBmt sidechain by heterocyclic rings |
| JP2019518745A (ja) * | 2016-05-17 | 2019-07-04 | エス アンド ティー グローバル インク． | 新規シクロスポリン誘導体及びその使用 |
| CA3046489A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| TW201834690A (zh) | 2016-12-14 | 2018-10-01 | 美商寶珍那提公司 | 以免疫抑制劑治療胃腸道疾病 |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2021173474A1 (en) * | 2020-02-26 | 2021-09-02 | Bacainn Biotherapeutics, Ltd. | Cyclosporine compositions and methods of use |
| CN113173974B (zh) * | 2021-03-18 | 2024-09-06 | 北京大学深圳研究生院 | 环孢素衍生物的合成方法 |
| WO2024254480A2 (en) * | 2023-06-08 | 2024-12-12 | Hepion Pharmaceuticals, Inc. | Solid state forms of rencofilstat |
| CN118834148B (zh) * | 2024-09-20 | 2025-01-21 | 天津凯莱英制药有限公司 | 一种l-青霉胺的制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0194972B1 (en) | 1985-03-11 | 1992-07-29 | Sandoz Ag | Novel cyclosporins |
| US4649047A (en) * | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
| US4839342A (en) | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
| US5474979A (en) * | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| FR2757522B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2757521B1 (fr) * | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2762843B1 (fr) | 1997-04-30 | 1999-12-10 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| WO1999065933A1 (en) * | 1998-06-12 | 1999-12-23 | C-Chem Ag | Novel cyclosporins |
| US6254860B1 (en) * | 1999-04-13 | 2001-07-03 | Allergan Sales, Inc. | Ocular treatment using cyclosporin-A derivatives |
| US20050059583A1 (en) * | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
| US7676680B2 (en) | 2005-07-08 | 2010-03-09 | Morgan Stanley | Systems and methods for distributing private placement documents |
| US7288520B2 (en) | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
| EP2023918B1 (en) | 2006-05-19 | 2011-03-23 | Scynexis, Inc. | Cyclosporins for the treatment and prevention of ocular disorders |
| CN101130058B (zh) * | 2006-08-23 | 2011-10-05 | 华北制药集团新药研究开发有限责任公司 | 一种环孢菌素a眼用乳剂及其制备方法 |
| BRPI0811538A2 (pt) * | 2007-05-04 | 2015-08-11 | Allergan Inc | Uso de ciclosporinas no tratamento de pacientes com lentes intraoculares. |
| JP5661035B2 (ja) * | 2008-07-10 | 2015-01-28 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 眼および皮膚の疾患および症状の治療用のシクロスポリン誘導体 |
| SG186084A1 (en) * | 2010-07-02 | 2013-01-30 | Exxonmobil Upstream Res Co | Low emission triple-cycle power generation systems and methods |
| US8902844B2 (en) | 2010-07-06 | 2014-12-02 | Lg Electronics Inc. | Method and device for allocating wireless resources for a machine type communication device in a wireless communication system |
| RU2013119869A (ru) * | 2010-10-12 | 2014-11-20 | Аллерган, Инк. | Аналоги циклоспорина |
| US9890198B2 (en) | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
| AU2011336266B2 (en) * | 2010-12-03 | 2017-04-06 | S&T Global Inc. | Novel cyclosporin derivatives for the treatment and prevention of a viral infection |
| CN103987399A (zh) * | 2011-08-19 | 2014-08-13 | 美国科技环球有限公司 | 用于治疗和预防病毒感染的新型环孢菌素衍生物 |
-
2011
- 2011-10-11 RU RU2013119869/04A patent/RU2013119869A/ru not_active Application Discontinuation
- 2011-10-11 CA CA2814192A patent/CA2814192A1/en not_active Abandoned
- 2011-10-11 CN CN2011800596461A patent/CN103328497A/zh active Pending
- 2011-10-11 US US13/270,964 patent/US20120088734A1/en not_active Abandoned
- 2011-10-11 BR BR112013008864A patent/BR112013008864A2/pt not_active Application Discontinuation
- 2011-10-11 KR KR1020137012145A patent/KR20140026329A/ko not_active Withdrawn
- 2011-10-11 MX MX2013004061A patent/MX2013004061A/es unknown
- 2011-10-11 JP JP2013533942A patent/JP5805774B2/ja not_active Expired - Fee Related
- 2011-10-11 AU AU2011316690A patent/AU2011316690C1/en not_active Ceased
- 2011-10-11 SG SG2013027339A patent/SG189880A1/en unknown
- 2011-10-11 WO PCT/US2011/055791 patent/WO2012051194A1/en not_active Ceased
- 2011-10-11 EP EP11770985.7A patent/EP2627664B1/en not_active Not-in-force
-
2013
- 2013-04-07 IL IL225617A patent/IL225617A0/en unknown
-
2014
- 2014-11-06 US US14/534,677 patent/US9493511B2/en active Active
-
2015
- 2015-09-02 JP JP2015173082A patent/JP6250608B2/ja not_active Expired - Fee Related
-
2016
- 2016-10-11 US US15/290,171 patent/US10065992B2/en active Active
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