JP2013535210A - パリンドローム配列を用いた閉鎖型直鎖状dnaの生成 - Google Patents

パリンドローム配列を用いた閉鎖型直鎖状dnaの生成 Download PDF

Info

Publication number
JP2013535210A
JP2013535210A JP2013522292A JP2013522292A JP2013535210A JP 2013535210 A JP2013535210 A JP 2013535210A JP 2013522292 A JP2013522292 A JP 2013522292A JP 2013522292 A JP2013522292 A JP 2013522292A JP 2013535210 A JP2013535210 A JP 2013535210A
Authority
JP
Japan
Prior art keywords
dna
seq
sequence
protelomerase
primer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013522292A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013535210A5 (https=
Inventor
ポーター,ネイル
カプローニー,リサ
カーバウニクゼック,キンガ
ナイト,アングス
オリバー,カレン
Original Assignee
タッチライト ジェネティックス リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by タッチライト ジェネティックス リミテッド filed Critical タッチライト ジェネティックス リミテッド
Publication of JP2013535210A publication Critical patent/JP2013535210A/ja
Publication of JP2013535210A5 publication Critical patent/JP2013535210A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6846Common amplification features

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2013522292A 2010-08-04 2011-08-04 パリンドローム配列を用いた閉鎖型直鎖状dnaの生成 Pending JP2013535210A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1013153.0A GB201013153D0 (en) 2010-08-04 2010-08-04 Primer for production of closed linear DNA
GB1013153.0 2010-08-04
PCT/GB2011/001175 WO2012017210A1 (en) 2010-08-04 2011-08-04 Production of closed linear dna using a palindromic sequence

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016202277A Division JP6689726B2 (ja) 2010-08-04 2016-10-14 パリンドローム配列を用いた閉鎖型直鎖状dnaの生成

Publications (2)

Publication Number Publication Date
JP2013535210A true JP2013535210A (ja) 2013-09-12
JP2013535210A5 JP2013535210A5 (https=) 2014-09-18

Family

ID=42931209

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013522292A Pending JP2013535210A (ja) 2010-08-04 2011-08-04 パリンドローム配列を用いた閉鎖型直鎖状dnaの生成
JP2016202277A Active JP6689726B2 (ja) 2010-08-04 2016-10-14 パリンドローム配列を用いた閉鎖型直鎖状dnaの生成

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016202277A Active JP6689726B2 (ja) 2010-08-04 2016-10-14 パリンドローム配列を用いた閉鎖型直鎖状dnaの生成

Country Status (6)

Country Link
US (1) US9499847B2 (https=)
EP (1) EP2601312B1 (https=)
JP (2) JP2013535210A (https=)
CN (1) CN103080337B (https=)
GB (1) GB201013153D0 (https=)
WO (1) WO2012017210A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017060650A1 (fr) 2015-10-08 2017-04-13 Jean-Marc Limacher Composition anti-tumorale
KR20170045349A (ko) * 2014-09-05 2017-04-26 터치라이트 아이피 리미티드 Dna의 합성
WO2018015995A1 (ja) * 2016-07-19 2018-01-25 株式会社バイオダイナミクス研究所 長鎖一本鎖dnaを調製する方法
JP2023511991A (ja) * 2020-01-31 2023-03-23 ティリス セラピューティクス,エセ.エレ. 閉じた直鎖dnaを作製するためのプロセス
JP2023533174A (ja) * 2020-06-12 2023-08-02 ユニバーシティ オブ ロチェスター ACE-tRNAのコード化及び発現
WO2024058155A1 (ja) * 2022-09-12 2024-03-21 株式会社カネカ 二本鎖環状dnaベクター、直鎖状共有結合閉鎖dnaの作製方法、並びにプロテロメラーゼ及びエンドヌクレアーゼを含む融合ポリペプチド
WO2025190971A1 (fr) 2024-03-13 2025-09-18 Odimma Therapeutics Vecteur non-viral pour transcription augmentee

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0901593D0 (en) * 2009-01-30 2009-03-11 Touchlight Genetics Ltd Production of closed linear DNA
EP2692870A1 (en) * 2012-08-03 2014-02-05 Alacris Theranostics GmbH Method for nucleic acid amplification
US9290800B2 (en) 2013-03-15 2016-03-22 Pacific Biosciences Of California, Inc. Targeted rolling circle amplification
US10450595B2 (en) 2013-03-15 2019-10-22 Theranos Ip Company, Llc Nucleic acid amplification
US20140302504A1 (en) 2013-03-15 2014-10-09 Theranos, Inc. Nucleic Acid Amplification
CN116334193A (zh) 2013-03-15 2023-06-27 赛拉诺斯知识产权有限责任公司 核酸扩增
SG11201507273SA (en) 2013-03-15 2015-10-29 Theranos Inc Nucleic acid amplification
SG11201601611WA (en) 2013-09-06 2016-04-28 Theranos Inc Systems and methods for detecting infectious diseases
US11028388B2 (en) 2014-03-05 2021-06-08 Editas Medicine, Inc. CRISPR/Cas-related methods and compositions for treating Usher syndrome and retinitis pigmentosa
ES2745769T3 (es) 2014-03-10 2020-03-03 Editas Medicine Inc Procedimientos y composiciones relacionados con CRISPR/CAS para tratar la amaurosis congénita de Leber 10 (LCA10)
US11339437B2 (en) 2014-03-10 2022-05-24 Editas Medicine, Inc. Compositions and methods for treating CEP290-associated disease
US11141493B2 (en) 2014-03-10 2021-10-12 Editas Medicine, Inc. Compositions and methods for treating CEP290-associated disease
EP3122880B1 (en) 2014-03-26 2021-05-05 Editas Medicine, Inc. Crispr/cas-related methods and compositions for treating sickle cell disease
EP3540061A1 (en) 2014-04-02 2019-09-18 Editas Medicine, Inc. Crispr/cas-related methods and compositions for treating primary open angle glaucoma
GB201502645D0 (en) * 2015-02-17 2015-04-01 Touchlight Genetics Ltd Method
JP2018522249A (ja) 2015-04-24 2018-08-09 エディタス・メディシン、インコーポレイテッド Cas9分子/ガイドrna分子複合体の評価
US11512311B2 (en) 2016-03-25 2022-11-29 Editas Medicine, Inc. Systems and methods for treating alpha 1-antitrypsin (A1AT) deficiency
BR112019001887A2 (pt) 2016-08-02 2019-07-09 Editas Medicine Inc composições e métodos para o tratamento de doença associada a cep290
CN109844134B (zh) * 2016-08-16 2023-05-05 塔驰莱特Ip有限公司 闭合线性dna的生产
WO2018170184A1 (en) 2017-03-14 2018-09-20 Editas Medicine, Inc. Systems and methods for the treatment of hemoglobinopathies
EP3622070A2 (en) 2017-05-10 2020-03-18 Editas Medicine, Inc. Crispr/rna-guided nuclease systems and methods
US11866726B2 (en) 2017-07-14 2024-01-09 Editas Medicine, Inc. Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites
US10350307B2 (en) * 2017-09-18 2019-07-16 General Electric Company In vivo RNA or protein expression using double-stranded concatemeric DNA including phosphorothioated nucleotides
DK3701028T3 (da) 2017-10-24 2024-11-11 Editas Medicine Inc Systemer og fremgangsmåder til behandling af hyper-igm-syndrom
US20200263206A1 (en) 2017-11-07 2020-08-20 Editas Medicine, Inc. Targeted integration systems and methods for the treatment of hemoglobinopathies
EP3724326A1 (en) 2017-12-11 2020-10-21 Editas Medicine, Inc. Cpf1-related methods and compositions for gene editing
WO2019118806A1 (en) * 2017-12-14 2019-06-20 Solid Biosciences Inc. Non-viral production and delivery of genes
KR102907245B1 (ko) 2018-03-14 2026-01-05 에디타스 메디신, 인코포레이티드 혈색소병증 치료를 위한 시스템 및 방법
CN108531496B (zh) * 2018-04-04 2020-11-06 江南大学 一种提高外源基因mRNA数量的DNA及其应用
GB201805683D0 (en) 2018-04-05 2018-05-23 Touchlight Ip Ltd Reprogramming vectors
EP3810782A2 (en) * 2018-06-22 2021-04-28 Asklepios Biopharmaceutical, Inc. Vectors for gene delivery that persist within cells
EP3986460A2 (en) 2019-06-18 2022-04-27 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 antibody
WO2020255010A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of recombinant interleukin 12 construct and hepatitis b virus (hbv) vaccines
KR20220041080A (ko) 2019-06-18 2022-03-31 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 B형 간염 바이러스(hbv) 백신 및 항-pd-1 또는 항-pc-l1 항체의 조합
WO2020254876A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Virus-like particle delivery of hepatitis b virus (hbv) vaccines
CA3143679A1 (en) 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and hbv-targeting rnai
US20250041386A1 (en) 2019-06-18 2025-02-06 Janssen Sciences Ireland Unlimited Company Recombinant Interleukin 12 Construct and Uses Thereof
KR20220042116A (ko) 2019-06-18 2022-04-04 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 B형 간염 바이러스(HBV) 백신 및 HBV-타케팅 RNAi의 조합
WO2020255062A1 (en) 2019-06-20 2020-12-24 Janssen Sciences Ireland Unlimited Company Lipid nanoparticle or liposome delivery of hepatitis b virus (hbv) vaccines
EP3986457A1 (en) 2019-06-20 2022-04-27 Janssen Sciences Ireland Unlimited Company Carbohydrate nanocarrier delivery of hepatitis b virus (hbv) vaccines
EP3792367A1 (en) 2019-09-11 2021-03-17 Universität Bielefeld Method for the production of raav and method for the in vitro generation of genetically engineered, linear, single-stranded nucleic acid fragments containing itr sequences flanking a gene of interest
KR20220128607A (ko) 2019-09-18 2022-09-21 인터갈락틱 테라퓨틱스, 인크. 합성 dna 벡터 및 사용 방법
GB201915163D0 (en) 2019-10-18 2019-12-04 Univ Southampton Cancer vaccine
GB202007428D0 (en) 2020-05-19 2020-07-01 Fabricnano Ltd Polynucleotide synthesis
CN112111544B (zh) * 2020-09-23 2022-04-01 复旦大学附属肿瘤医院 提高单链dna连接效率的方法
US20240084285A1 (en) * 2021-01-22 2024-03-14 Nanjing GenScript Biotech Co., Ltd. Method for producing target dna sequence and cloning vector
ES2960777T3 (es) * 2021-03-18 2024-03-06 Genomill Health Oy Métodos para la cuantificación paralela precisa de ácidos nucleicos en muestras diluidas o no purificadas
MX2023014228A (es) 2021-06-08 2024-01-25 Touchlight Ip Ltd Vector lentiviral.
GB202108176D0 (en) 2021-06-08 2021-07-21 Touchlight Ip Ltd Vector
AU2022299552A1 (en) 2021-06-25 2024-01-04 Oxford Biomedica (Us) Llc Adeno-associated virus packaging systems
CA3226725A1 (en) 2021-07-13 2023-01-19 Stonehaven Incubate AG Composition and uses thereof
GB202114105D0 (en) 2021-10-01 2021-11-17 Fabricnano Ltd Nucleotide synthesis
WO2023069948A1 (en) 2021-10-18 2023-04-27 Flagship Pioneering Innovations Vii, Llc Dna compositions and related methods
WO2023114897A2 (en) 2021-12-15 2023-06-22 Homology Medicines, Inc. Methods and compositions for the production of adeno-associated virus
US20250127873A1 (en) 2021-12-20 2025-04-24 Zoetis Services Llc Compositions and methods for prevention of piscine myocarditis
CN118414349A (zh) 2021-12-20 2024-07-30 硕腾服务有限责任公司 用于在细胞膜上表达抗原的组合物和方法
US20250057946A1 (en) 2021-12-20 2025-02-20 Zoetis Services Llc Use of interferon as an adjuvant in vaccines
CN114561372B (zh) * 2022-04-27 2022-07-26 南京巨匠生物科技有限公司 Bst DNA聚合酶突变体及其应用和产品、基因、重组质粒和基因工程菌
EP4293101A1 (en) 2022-06-14 2023-12-20 Asklepios Biopharmaceutical, Inc. Reactor with temperature control and method of using the same
CN119698477A (zh) * 2022-08-10 2025-03-25 镇江蓬勃生物科技有限公司 线性闭合dna的制备方法及该方法所用质粒
WO2024039652A1 (en) 2022-08-16 2024-02-22 Aldevron, L.L.C. Cell-free method of producing synthetic circular nucleic acid
WO2024059486A1 (en) 2022-09-12 2024-03-21 Zoetis Services Llc Method of administration of aquaculture vaccines
CN117778498A (zh) * 2022-09-26 2024-03-29 深圳瑞吉生物科技有限公司 一种无细胞制备mRNA转录模板的方法
EP4593877A1 (en) 2022-09-29 2025-08-06 Ceva Hampton Limited Vaccine construct and uses thereof
WO2024121354A1 (en) * 2022-12-08 2024-06-13 Keygene N.V. Duplex sequencing with covalently closed dna ends
DK202370610A1 (en) 2022-12-13 2024-07-12 Zoetis Services Llc Methods of vaccine administration to salmonids
WO2024197081A1 (en) 2023-03-20 2024-09-26 Hc Bioscience, Inc. Minimally-sized dna threads for trna therapy
CN116606834A (zh) * 2023-04-10 2023-08-18 天津中合基因科技有限公司 多种具有切割连接活性的原端酶及其应用
WO2024256842A1 (en) 2023-06-16 2024-12-19 Touchlight IP Limited Therapeutic transfection
CN121816413A (zh) 2023-08-18 2026-04-07 镇江蓬勃生物科技有限公司 纯化核酸分子的方法
US11981936B1 (en) 2023-09-29 2024-05-14 New England Biolabs, Inc. TelA variants, compositions, and methods
GB202319998D0 (en) 2023-12-22 2024-02-07 Touchlight Ip Ltd duplexing method
WO2025202929A1 (en) * 2024-03-29 2025-10-02 Pfizer Inc. Methods for producing nucleic acids
WO2025250742A1 (en) * 2024-05-30 2025-12-04 Aclarity Genomics, Inc. Amplification of macromolecules
WO2025264964A1 (en) 2024-06-20 2025-12-26 Zoetis Services Llc Vaccines against tenacibaculum finnmarkense
EP4729632A1 (en) 2024-10-18 2026-04-22 AskBio Inc. Method of synthesizing dna

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10234399A (ja) * 1997-02-28 1998-09-08 Shinkinrui Kinou Kaihatsu Kenkyusho:Kk ピシウム属菌検出用の核酸配列
US20030170693A1 (en) * 2001-12-21 2003-09-11 George Chaconas Assay for identifying modulators of Borrelia telomere resolvase
JP2008522628A (ja) * 2004-12-11 2008-07-03 サイトジェニックス, インコーポレイテッド 高品質核酸のセルフリー生合成及びその使用
WO2010026099A1 (en) * 2008-09-02 2010-03-11 General Electric Company Dna mini-circles and uses thereof
WO2010086626A1 (en) * 2009-01-30 2010-08-05 Touchlight Genetics Limited Production of closed linear dna

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
JPH03236781A (ja) * 1990-02-13 1991-10-22 Takara Shuzo Co Ltd ランダムプライマーキット及びその使用方法
AU649066B2 (en) 1990-07-25 1994-05-12 Syngene, Inc. Circular extension for generating multiple nucleic acid complements
FR2675803B1 (fr) 1991-04-25 1996-09-06 Genset Sa Oligonucleotides fermes, antisens et sens et leurs applications.
US6953676B1 (en) 1992-05-01 2005-10-11 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
WO1994003624A1 (en) * 1992-08-04 1994-02-17 Auerbach Jeffrey I Methods for the isothermal amplification of nucleic acid molecules
US5714320A (en) 1993-04-15 1998-02-03 University Of Rochester Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides
DE69429038T2 (de) 1993-07-28 2002-03-21 Pe Corporation (Ny), Norwalk Vorrichtung und Verfahren zur Nukleinsäurevervielfältigung
WO1995011923A1 (en) * 1993-10-29 1995-05-04 Dana-Farber Cancer Institute, Inc. A novel tumor marker and novel method of isolating same
FR2732971B1 (fr) 1995-04-13 1997-07-04 Genset Sa Oligonucleotide sens inhibiteur de virus herpes simplex (hsv) a structure en haltere
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
DK0862656T3 (da) 1995-11-21 2001-04-09 Univ Yale Unimolekylær segmentamplifikation og -detektering
DE19648625A1 (de) 1996-11-13 1998-05-14 Soft Gene Gmbh Mikroprojektil für das Einbringen von Substanzen in Zellen durch ballistischen Transfer
US6054274A (en) * 1997-11-12 2000-04-25 Hewlett-Packard Company Method of amplifying the signal of target nucleic acid sequence analyte
EP1179585B1 (en) 1997-12-24 2008-07-09 Cepheid Device and method for lysis
US6620597B1 (en) 1998-01-09 2003-09-16 University Of Utah Research Foundation Method for in vitro amplification of circular DNA
DE19826758C1 (de) 1998-06-15 1999-10-21 Soft Gene Gmbh Darstellung von linearen kovalent geschlossenen DNA-Molekülen als Expressionskonstrukte
JP2002525049A (ja) 1998-09-15 2002-08-13 イェール ユニバーシティ ローリングサークル増幅を用いる分子クローニング
WO2001004280A2 (de) 1999-07-08 2001-01-18 Mologen Forschungs-, Entwicklungs- Und Vertriebs Gmbh Impfstoff gegen infektionen mit lentiviren, wie dem felinen immunschwäche-virus der katze
EP1268856A2 (de) * 2000-04-07 2003-01-02 Epigenomics AG Detektion von snp's und cytosin-methylierungen
GB0018120D0 (en) 2000-07-24 2000-09-13 Fermentas Ab Nuclease
JP2002051784A (ja) * 2000-08-09 2002-02-19 Toyobo Co Ltd 核酸の増幅方法及び標識核酸の調製方法
US6977148B2 (en) 2001-10-15 2005-12-20 Qiagen Gmbh Multiple displacement amplification
US20030077611A1 (en) 2001-10-24 2003-04-24 Sention Methods and systems for dynamic gene expression profiling
US7081339B2 (en) 2002-04-12 2006-07-25 Primera Biosystems, Inc. Methods for variation detection
CA2492203A1 (en) 2002-07-12 2004-01-22 Affymetrix, Inc. Synthetic tag genes
DE10393824D2 (de) 2002-09-23 2005-08-11 Mologen Ag Impfstoff gegen Infektionen mit Onkoviren, wie dem felinen Leukosevirus der Katze
US7955795B2 (en) 2003-06-06 2011-06-07 Qiagen Gmbh Method of whole genome amplification with reduced artifact production
US7452699B2 (en) 2003-01-15 2008-11-18 Dana-Farber Cancer Institute, Inc. Amplification of DNA in a hairpin structure, and applications
ATE432365T1 (de) 2003-02-21 2009-06-15 Geneform Technologies Ltd Verfahren, kits und reagenzien zur nukleinsäuresequenzierung
EP1706502A4 (en) 2003-11-26 2007-05-23 Eppendorf Ag METHODS AND COMPOSITIONS FOR IN VITRO AMPLIFICATION OF EXTRACHROMOSOMIC NUCLEIC ACID
JP3972106B2 (ja) * 2004-03-03 2007-09-05 大学共同利用機関法人情報・システム研究機構 ゲノムライブラリー作製方法、および同方法により作製されたゲノムライブラリー
CN101103122A (zh) * 2004-12-11 2008-01-09 西托吉尼克斯公司 高质量核酸的无细胞生物合成及其用途
EP1871897B1 (en) 2005-04-12 2010-09-29 Olink AB Methods for production of oligonucleotides
AU2006242387B2 (en) 2005-04-29 2011-01-06 Synthetic Genomics, Inc. Amplification and cloning of single DNA molecules using rolling circle amplification
ATE549408T1 (de) 2006-01-12 2012-03-15 Lucigen Corp Lineare vektoren, wirtszellen und klonverfahren
CN101589157B (zh) 2006-10-06 2014-04-02 万达利亚研究公司 用于连续快速热循环系统的方法
US20080118917A1 (en) * 2006-11-21 2008-05-22 Applera Corporation Isothermal SNP Detection Method
JP5182949B2 (ja) * 2009-03-31 2013-04-17 浜名部品工業株式会社 ヨークの製造方法及び製造装置
US9114399B2 (en) 2010-08-31 2015-08-25 Canon U.S. Life Sciences, Inc. System and method for serial processing of multiple nucleic acid assays
EP2692870A1 (en) 2012-08-03 2014-02-05 Alacris Theranostics GmbH Method for nucleic acid amplification
KR102014989B1 (ko) 2013-04-15 2019-08-27 삼성전자주식회사 폴리뉴클레오티드 및 그의 용도

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10234399A (ja) * 1997-02-28 1998-09-08 Shinkinrui Kinou Kaihatsu Kenkyusho:Kk ピシウム属菌検出用の核酸配列
US20030170693A1 (en) * 2001-12-21 2003-09-11 George Chaconas Assay for identifying modulators of Borrelia telomere resolvase
JP2008522628A (ja) * 2004-12-11 2008-07-03 サイトジェニックス, インコーポレイテッド 高品質核酸のセルフリー生合成及びその使用
WO2010026099A1 (en) * 2008-09-02 2010-03-11 General Electric Company Dna mini-circles and uses thereof
WO2010086626A1 (en) * 2009-01-30 2010-08-05 Touchlight Genetics Limited Production of closed linear dna

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6015029950; HEINRICH, J. et al.: J. Mol. Med. Vol.80, 2002, pp.648-654 *
JPN6015029951; MORENO, S. et al.: Vaccine Vol.22, 2004, pp.1709-1716 *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102497228B1 (ko) * 2014-09-05 2023-02-07 터치라이트 아이피 리미티드 Dna의 합성
KR20170045349A (ko) * 2014-09-05 2017-04-26 터치라이트 아이피 리미티드 Dna의 합성
JP2017525384A (ja) * 2014-09-05 2017-09-07 タッチライト・アイピー・リミテッド Dnaの合成
WO2017060650A1 (fr) 2015-10-08 2017-04-13 Jean-Marc Limacher Composition anti-tumorale
WO2018015995A1 (ja) * 2016-07-19 2018-01-25 株式会社バイオダイナミクス研究所 長鎖一本鎖dnaを調製する方法
JP7004651B2 (ja) 2016-07-19 2022-02-04 株式会社バイオダイナミクス研究所 長鎖一本鎖dnaを調製する方法
JPWO2018015995A1 (ja) * 2016-07-19 2019-05-09 株式会社バイオダイナミクス研究所 長鎖一本鎖dnaを調製する方法
JP2023511991A (ja) * 2020-01-31 2023-03-23 ティリス セラピューティクス,エセ.エレ. 閉じた直鎖dnaを作製するためのプロセス
JP7771066B2 (ja) 2020-01-31 2025-11-17 ティリス セラピューティクス,エセ.エレ. 閉じた直鎖dnaを作製するためのプロセス
JP2023533174A (ja) * 2020-06-12 2023-08-02 ユニバーシティ オブ ロチェスター ACE-tRNAのコード化及び発現
WO2024058155A1 (ja) * 2022-09-12 2024-03-21 株式会社カネカ 二本鎖環状dnaベクター、直鎖状共有結合閉鎖dnaの作製方法、並びにプロテロメラーゼ及びエンドヌクレアーゼを含む融合ポリペプチド
WO2025190971A1 (fr) 2024-03-13 2025-09-18 Odimma Therapeutics Vecteur non-viral pour transcription augmentee
FR3160186A1 (fr) 2024-03-13 2025-09-19 Odimma Therapeutics Vecteur non-viral pour transcription augmentee

Also Published As

Publication number Publication date
EP2601312B1 (en) 2017-04-12
WO2012017210A1 (en) 2012-02-09
EP2601312A1 (en) 2013-06-12
GB201013153D0 (en) 2010-09-22
CN103080337A (zh) 2013-05-01
US9499847B2 (en) 2016-11-22
JP6689726B2 (ja) 2020-04-28
JP2017035102A (ja) 2017-02-16
CN103080337B (zh) 2016-08-17
US20130216562A1 (en) 2013-08-22

Similar Documents

Publication Publication Date Title
JP6689726B2 (ja) パリンドローム配列を用いた閉鎖型直鎖状dnaの生成
JP6454243B2 (ja) 閉鎖型直鎖状dnaの製造
US12509718B2 (en) Method of DNA synthesis
HK1215045A1 (zh) 用於制备闭合线状dna的体外无细胞方法的试剂盒
HK1159693B (en) Production of closed linear dna

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140729

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140729

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150728

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20151019

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160128

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20160614