CN103080337B - 利用回文序列生产闭合线性dna - Google Patents
利用回文序列生产闭合线性dna Download PDFInfo
- Publication number
- CN103080337B CN103080337B CN201180038378.5A CN201180038378A CN103080337B CN 103080337 B CN103080337 B CN 103080337B CN 201180038378 A CN201180038378 A CN 201180038378A CN 103080337 B CN103080337 B CN 103080337B
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- China
- Prior art keywords
- dna
- seq
- protelomerase
- template
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6846—Common amplification features
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1013153.0 | 2010-08-04 | ||
| GBGB1013153.0A GB201013153D0 (en) | 2010-08-04 | 2010-08-04 | Primer for production of closed linear DNA |
| PCT/GB2011/001175 WO2012017210A1 (en) | 2010-08-04 | 2011-08-04 | Production of closed linear dna using a palindromic sequence |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103080337A CN103080337A (zh) | 2013-05-01 |
| CN103080337B true CN103080337B (zh) | 2016-08-17 |
Family
ID=42931209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180038378.5A Active CN103080337B (zh) | 2010-08-04 | 2011-08-04 | 利用回文序列生产闭合线性dna |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9499847B2 (https=) |
| EP (1) | EP2601312B1 (https=) |
| JP (2) | JP2013535210A (https=) |
| CN (1) | CN103080337B (https=) |
| GB (1) | GB201013153D0 (https=) |
| WO (1) | WO2012017210A1 (https=) |
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| US10450595B2 (en) | 2013-03-15 | 2019-10-22 | Theranos Ip Company, Llc | Nucleic acid amplification |
| US9290800B2 (en) | 2013-03-15 | 2016-03-22 | Pacific Biosciences Of California, Inc. | Targeted rolling circle amplification |
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| EP2692870A1 (en) | 2012-08-03 | 2014-02-05 | Alacris Theranostics GmbH | Method for nucleic acid amplification |
| KR102014989B1 (ko) | 2013-04-15 | 2019-08-27 | 삼성전자주식회사 | 폴리뉴클레오티드 및 그의 용도 |
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- 2011-08-04 CN CN201180038378.5A patent/CN103080337B/zh active Active
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| WO2001077384A2 (de) * | 2000-04-07 | 2001-10-18 | Epigenomics Ag | DETEKTION VON SNPs UND CYTOSIN-METHYLIERUNGEN |
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| Linear closed mini DNA generated by the prokaryotic cleaving-joining enzyme TelN is functional in mammalian cells;Jochen Heinrich et al.;《Journal of Molecular Medicine》;20080828;第80卷(第10期);摘要，第649页第2-6段 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6689726B2 (ja) | 2020-04-28 |
| JP2017035102A (ja) | 2017-02-16 |
| EP2601312B1 (en) | 2017-04-12 |
| US20130216562A1 (en) | 2013-08-22 |
| JP2013535210A (ja) | 2013-09-12 |
| US9499847B2 (en) | 2016-11-22 |
| WO2012017210A1 (en) | 2012-02-09 |
| GB201013153D0 (en) | 2010-09-22 |
| EP2601312A1 (en) | 2013-06-12 |
| CN103080337A (zh) | 2013-05-01 |
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