JP2013529676A5 - - Google Patents
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- Publication number
- JP2013529676A5 JP2013529676A5 JP2013517610A JP2013517610A JP2013529676A5 JP 2013529676 A5 JP2013529676 A5 JP 2013529676A5 JP 2013517610 A JP2013517610 A JP 2013517610A JP 2013517610 A JP2013517610 A JP 2013517610A JP 2013529676 A5 JP2013529676 A5 JP 2013529676A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- compound
- alkyl
- substituted
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BJHIVDUGNUZYGO-SMDDNHRTSA-N CC[C@H]([C@@H](C)CNC)c1cccc(OC)c1 Chemical compound CC[C@H]([C@@H](C)CNC)c1cccc(OC)c1 BJHIVDUGNUZYGO-SMDDNHRTSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A001224A IT1401109B1 (it) | 2010-07-02 | 2010-07-02 | Nuovo processo per la preparazione di tapentadol e suoi intermedi. |
| ITMI2010A001224 | 2010-07-02 | ||
| PCT/IB2011/052685 WO2012001571A1 (en) | 2010-07-02 | 2011-06-20 | New process for the synthesis of tapentadol and intermediates thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013529676A JP2013529676A (ja) | 2013-07-22 |
| JP2013529676A5 true JP2013529676A5 (https=) | 2014-05-15 |
| JP5857044B2 JP5857044B2 (ja) | 2016-02-10 |
Family
ID=43432160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013517610A Expired - Fee Related JP5857044B2 (ja) | 2010-07-02 | 2011-06-20 | タペンタドールおよびその中間体を合成する新規のプロセス |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8791287B2 (https=) |
| EP (1) | EP2588429B1 (https=) |
| JP (1) | JP5857044B2 (https=) |
| CN (1) | CN102958868B (https=) |
| AU (1) | AU2011273044B2 (https=) |
| BR (1) | BR112012029882A2 (https=) |
| CA (1) | CA2797757C (https=) |
| CL (1) | CL2012003760A1 (https=) |
| ES (1) | ES2572637T3 (https=) |
| IL (1) | IL223066A (https=) |
| IT (1) | IT1401109B1 (https=) |
| MX (1) | MX340833B (https=) |
| WO (1) | WO2012001571A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013111161A2 (en) * | 2012-01-10 | 2013-08-01 | Msn Laboratories Limited | Process for the preparation of 3-aryl-2-methyl-propanamine derivatives and polymorphs thereof |
| EP2674414A1 (en) | 2012-06-15 | 2013-12-18 | Siegfried AG | Method for the preparation of 1-aryl-1-alkyl-3-dialkylaminopropane compounds |
| US9090539B2 (en) | 2013-05-24 | 2015-07-28 | Ampac Fine Chemicals Llc | Compounds and methods for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds |
| CZ307492B6 (cs) | 2014-02-04 | 2018-10-17 | Zentiva, K.S. | Pevná forma maleátu tapentadolu a způsob její přípravy |
| EP4116288A1 (en) | 2021-07-08 | 2023-01-11 | KRKA, d.d., Novo mesto | Racemization of (s) and/or (r)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1- one and its mixtures |
| CN113861155A (zh) * | 2021-10-21 | 2021-12-31 | 华南师范大学 | 一种二氢异香豆素类衍生物及其制备方法与应用 |
| CN119191999A (zh) * | 2024-11-26 | 2024-12-27 | 苏州盛迪亚生物医药有限公司 | 一种制备他喷他多或其可药用盐的方法 |
| CN119176758B (zh) * | 2024-11-26 | 2025-05-09 | 苏州盛迪亚生物医药有限公司 | 一种固载催化制备他喷他多或其可药用盐的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US429833A (en) | 1890-06-10 | Means for creating artificial currents | ||
| US3888901A (en) | 1972-07-20 | 1975-06-10 | American Cyanamid Co | Process of preparing 3-alkyl-3-(benzoyl)propionitriles |
| DE2901180A1 (de) * | 1979-01-13 | 1980-07-24 | Basf Ag | Hexahydro-1,4-oxazepine, verfahren zu deren herstellung und diese enthaltende arzneimittel |
| DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| DE10326097A1 (de) | 2003-06-06 | 2005-01-05 | Grünenthal GmbH | Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen |
| TWI496762B (zh) * | 2006-07-24 | 2015-08-21 | 製備（１ｒ，２ｒ）-３-（３-二甲胺基-１-乙基-２-甲基-丙基）-酚之方法 | |
| TWI401237B (zh) * | 2006-07-24 | 2013-07-11 | ３-〔（１ｒ，２ｒ）-３-（二甲基氨基）-１-乙基-２-甲基丙基〕酚之製備 | |
| BRPI0714671B8 (pt) * | 2006-07-24 | 2023-03-21 | Janssen Pharmaceutica Nv | Preparação de (2r,3r)-3-(3-metoxifenil)-n,n,2-trimetilpentanamina e compostos intermediários |
-
2010
- 2010-07-02 IT ITMI2010A001224A patent/IT1401109B1/it active
-
2011
- 2011-06-20 WO PCT/IB2011/052685 patent/WO2012001571A1/en not_active Ceased
- 2011-06-20 CA CA2797757A patent/CA2797757C/en active Active
- 2011-06-20 CN CN201180022910.4A patent/CN102958868B/zh not_active Expired - Fee Related
- 2011-06-20 AU AU2011273044A patent/AU2011273044B2/en not_active Ceased
- 2011-06-20 EP EP11735552.9A patent/EP2588429B1/en active Active
- 2011-06-20 US US13/807,356 patent/US8791287B2/en active Active
- 2011-06-20 MX MX2012015161A patent/MX340833B/es active IP Right Grant
- 2011-06-20 JP JP2013517610A patent/JP5857044B2/ja not_active Expired - Fee Related
- 2011-06-20 BR BR112012029882A patent/BR112012029882A2/pt not_active IP Right Cessation
- 2011-06-20 ES ES11735552.9T patent/ES2572637T3/es active Active
-
2012
- 2012-11-15 IL IL223066A patent/IL223066A/en active IP Right Grant
- 2012-12-31 CL CL2012003760A patent/CL2012003760A1/es unknown
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