JP2013527767A5 - - Google Patents
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- Publication number
- JP2013527767A5 JP2013527767A5 JP2013509272A JP2013509272A JP2013527767A5 JP 2013527767 A5 JP2013527767 A5 JP 2013527767A5 JP 2013509272 A JP2013509272 A JP 2013509272A JP 2013509272 A JP2013509272 A JP 2013509272A JP 2013527767 A5 JP2013527767 A5 JP 2013527767A5
- Authority
- JP
- Japan
- Prior art keywords
- variant
- subtilisin
- amino acid
- protease
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000203 mixture Substances 0.000 claims 17
- 108090000787 Subtilisin Proteins 0.000 claims 16
- 125000003275 alpha amino acid group Chemical group 0.000 claims 14
- 108091005804 Peptidases Proteins 0.000 claims 11
- 239000004365 Protease Substances 0.000 claims 11
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 11
- 238000004140 cleaning Methods 0.000 claims 8
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
- 238000010998 test method Methods 0.000 claims 4
- 241000193422 Bacillus lentus Species 0.000 claims 3
- -1 bar Substances 0.000 claims 3
- 238000006467 substitution reaction Methods 0.000 claims 3
- 101000642797 Bacillus amyloliquefaciens Subtilisin BPN' Proteins 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 2
- 229940088598 enzyme Drugs 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 2
- 239000010452 phosphate Substances 0.000 claims 2
- 230000002797 proteolythic effect Effects 0.000 claims 2
- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 claims 1
- 239000004382 Amylase Substances 0.000 claims 1
- 108010065511 Amylases Proteins 0.000 claims 1
- 102000013142 Amylases Human genes 0.000 claims 1
- 241000193830 Bacillus <bacterium> Species 0.000 claims 1
- 101710130006 Beta-glucanase Proteins 0.000 claims 1
- 102100032487 Beta-mannosidase Human genes 0.000 claims 1
- 108010059892 Cellulase Proteins 0.000 claims 1
- 108010023736 Chondroitinases and Chondroitin Lyases Proteins 0.000 claims 1
- 102000011413 Chondroitinases and Chondroitin Lyases Human genes 0.000 claims 1
- 102220465972 Cilium assembly protein DZIP1_S24R_mutation Human genes 0.000 claims 1
- 101710121765 Endo-1,4-beta-xylanase Proteins 0.000 claims 1
- 108090000371 Esterases Proteins 0.000 claims 1
- 108010003272 Hyaluronate lyase Proteins 0.000 claims 1
- 102000001974 Hyaluronidases Human genes 0.000 claims 1
- 108010029541 Laccase Proteins 0.000 claims 1
- 108090001060 Lipase Proteins 0.000 claims 1
- 102000004882 Lipase Human genes 0.000 claims 1
- 239000004367 Lipase Substances 0.000 claims 1
- 102220642080 Lipoma-preferred partner_N43R_mutation Human genes 0.000 claims 1
- 102000003820 Lipoxygenases Human genes 0.000 claims 1
- 108090000128 Lipoxygenases Proteins 0.000 claims 1
- 102000005741 Metalloproteases Human genes 0.000 claims 1
- 108010006035 Metalloproteases Proteins 0.000 claims 1
- 102000004316 Oxidoreductases Human genes 0.000 claims 1
- 108090000854 Oxidoreductases Proteins 0.000 claims 1
- 102000003992 Peroxidases Human genes 0.000 claims 1
- 108010064785 Phospholipases Proteins 0.000 claims 1
- 102000015439 Phospholipases Human genes 0.000 claims 1
- 108010059820 Polygalacturonase Proteins 0.000 claims 1
- 102220610345 Spectrin alpha chain, erythrocytic 1_R45T_mutation Human genes 0.000 claims 1
- 102000003425 Tyrosinase Human genes 0.000 claims 1
- 108060008724 Tyrosinase Proteins 0.000 claims 1
- 108090000637 alpha-Amylases Proteins 0.000 claims 1
- 108010084650 alpha-N-arabinofuranosidase Proteins 0.000 claims 1
- 235000019418 amylase Nutrition 0.000 claims 1
- 108010055059 beta-Mannosidase Proteins 0.000 claims 1
- 239000007844 bleaching agent Substances 0.000 claims 1
- 229940106157 cellulase Drugs 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 108010005400 cutinase Proteins 0.000 claims 1
- YERABYSOHUZTPQ-UHFFFAOYSA-P endo-1,4-beta-Xylanase Chemical compound C=1C=CC=CC=1C[N+](CC)(CC)CCCNC(C(C=1)=O)=CC(=O)C=1NCCC[N+](CC)(CC)CC1=CC=CC=C1 YERABYSOHUZTPQ-UHFFFAOYSA-P 0.000 claims 1
- 108010093305 exopolygalacturonase Proteins 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- 108010002430 hemicellulase Proteins 0.000 claims 1
- 229940059442 hemicellulase Drugs 0.000 claims 1
- 229960002773 hyaluronidase Drugs 0.000 claims 1
- 108010059345 keratinase Proteins 0.000 claims 1
- 108010062085 ligninase Proteins 0.000 claims 1
- 235000019421 lipase Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 108010087558 pectate lyase Proteins 0.000 claims 1
- 229940072417 peroxidase Drugs 0.000 claims 1
- 108040007629 peroxidase activity proteins Proteins 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 102200104664 rs121908724 Human genes 0.000 claims 1
- 102220042823 rs35942089 Human genes 0.000 claims 1
- 102200025035 rs786203989 Human genes 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 108010038851 tannase Proteins 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33200610P | 2010-05-06 | 2010-05-06 | |
| US33215110P | 2010-05-06 | 2010-05-06 | |
| US61/332,006 | 2010-05-06 | ||
| US61/332,151 | 2010-05-06 | ||
| US39218810P | 2010-10-12 | 2010-10-12 | |
| US39236410P | 2010-10-12 | 2010-10-12 | |
| US61/392,364 | 2010-10-12 | ||
| US61/392,188 | 2010-10-12 | ||
| PCT/US2011/035389 WO2011140364A1 (en) | 2010-05-06 | 2011-05-05 | Compositions and methods comprising subtilisin variants |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015235701A Division JP6567964B2 (ja) | 2010-05-06 | 2015-12-02 | サブチリシン変異体を含む組成物及び方法 |
| JP2017162468A Division JP2018029592A (ja) | 2010-05-06 | 2017-08-25 | サブチリシン変異体を含む組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013527767A JP2013527767A (ja) | 2013-07-04 |
| JP2013527767A5 true JP2013527767A5 (enExample) | 2014-06-19 |
| JP6448904B2 JP6448904B2 (ja) | 2019-01-09 |
Family
ID=44140761
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509272A Active JP6448904B2 (ja) | 2010-05-06 | 2011-05-05 | サブチリシン変異体を含む組成物及び方法 |
| JP2013509256A Active JP5813753B2 (ja) | 2010-05-06 | 2011-05-05 | プロテアーゼ変異体を有する消費者製品 |
| JP2015107987A Pending JP2015187278A (ja) | 2010-05-06 | 2015-05-27 | プロテアーゼ変異体を有する消費者製品 |
| JP2015235701A Active JP6567964B2 (ja) | 2010-05-06 | 2015-12-02 | サブチリシン変異体を含む組成物及び方法 |
| JP2017162468A Pending JP2018029592A (ja) | 2010-05-06 | 2017-08-25 | サブチリシン変異体を含む組成物及び方法 |
| JP2018005572A Active JP7002345B2 (ja) | 2010-05-06 | 2018-01-17 | サブチリシン変異体を含む組成物及び方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509256A Active JP5813753B2 (ja) | 2010-05-06 | 2011-05-05 | プロテアーゼ変異体を有する消費者製品 |
| JP2015107987A Pending JP2015187278A (ja) | 2010-05-06 | 2015-05-27 | プロテアーゼ変異体を有する消費者製品 |
| JP2015235701A Active JP6567964B2 (ja) | 2010-05-06 | 2015-12-02 | サブチリシン変異体を含む組成物及び方法 |
| JP2017162468A Pending JP2018029592A (ja) | 2010-05-06 | 2017-08-25 | サブチリシン変異体を含む組成物及び方法 |
| JP2018005572A Active JP7002345B2 (ja) | 2010-05-06 | 2018-01-17 | サブチリシン変異体を含む組成物及び方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20130260438A1 (enExample) |
| EP (7) | EP3095861B1 (enExample) |
| JP (6) | JP6448904B2 (enExample) |
| CN (5) | CN105925555B (enExample) |
| BR (2) | BR112012028466B1 (enExample) |
| CA (1) | CA2798451C (enExample) |
| DK (4) | DK3868881T3 (enExample) |
| ES (4) | ES2694398T3 (enExample) |
| HU (3) | HUE034524T2 (enExample) |
| MX (2) | MX339810B (enExample) |
| PL (3) | PL3095861T3 (enExample) |
| RU (2) | RU2598717C2 (enExample) |
| WO (2) | WO2011140316A1 (enExample) |
| ZA (1) | ZA201208019B (enExample) |
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| WO2011072117A1 (en) | 2009-12-09 | 2011-06-16 | The Procter & Gamble Company | Fabric and home care products |
| EP2365055B1 (en) | 2010-03-01 | 2017-12-20 | The Procter and Gamble Company | Composition comprising substituted cellulosic polymer and amylase |
| PL3095861T3 (pl) * | 2010-05-06 | 2020-04-30 | The Procter & Gamble Company | Produkty konsumenckie z odmianami proteaz |
| MX357386B (es) * | 2011-05-05 | 2018-07-06 | Procter & Gamble | Composiciones y metodos que comprenden variantes de proteasa serina. |
| EP4230735A1 (en) | 2011-05-05 | 2023-08-23 | Danisco US Inc. | Compositions and methods comprising serine protease variants |
| EP2540824A1 (en) | 2011-06-30 | 2013-01-02 | The Procter & Gamble Company | Cleaning compositions comprising amylase variants reference to a sequence listing |
| EP2551335A1 (en) | 2011-07-25 | 2013-01-30 | The Procter & Gamble Company | Enzyme stabilized liquid detergent composition |
| US20130123162A1 (en) * | 2011-11-10 | 2013-05-16 | The Procter & Gamble Company | Consumer products |
| WO2014099523A1 (en) | 2012-12-21 | 2014-06-26 | Danisco Us Inc. | Alpha-amylase variants |
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| JP6367930B2 (ja) | 2013-05-29 | 2018-08-01 | ダニスコ・ユーエス・インク | 新規メタロプロテアーゼ |
| EP3882346B1 (en) | 2013-05-29 | 2025-10-01 | Danisco US Inc. | Novel metalloproteases |
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| ES2835703T3 (es) | 2013-12-18 | 2021-06-23 | Nutrition & Biosciences Usa 4 Inc | Eteres de poli alfa-1,3-glucano catiónicos |
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| EP3919599A1 (en) | 2014-06-19 | 2021-12-08 | Nutrition & Biosciences USA 4, Inc. | Compositions containing one or more poly alpha-1,3-glucan ether compounds |
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