JP2013521485A5 - - Google Patents

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Publication number
JP2013521485A5
JP2013521485A5 JP2012555389A JP2012555389A JP2013521485A5 JP 2013521485 A5 JP2013521485 A5 JP 2013521485A5 JP 2012555389 A JP2012555389 A JP 2012555389A JP 2012555389 A JP2012555389 A JP 2012555389A JP 2013521485 A5 JP2013521485 A5 JP 2013521485A5
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JP
Japan
Prior art keywords
value
polypeptide
interest
gradient
mobile phase
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JP2012555389A
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English (en)
Japanese (ja)
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JP5992836B2 (ja
JP2013521485A (ja
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Priority claimed from PCT/EP2011/052964 external-priority patent/WO2011107447A1/en
Publication of JP2013521485A publication Critical patent/JP2013521485A/ja
Publication of JP2013521485A5 publication Critical patent/JP2013521485A5/ja
Application granted granted Critical
Publication of JP5992836B2 publication Critical patent/JP5992836B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012555389A 2010-03-01 2011-03-01 ペプチドを精製するための分取rp−hplc法 Expired - Fee Related JP5992836B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP10155023.4 2010-03-01
EP10155023 2010-03-01
US30964210P 2010-03-02 2010-03-02
US61/309,642 2010-03-02
PCT/EP2011/052964 WO2011107447A1 (en) 2010-03-01 2011-03-01 Preparative rp-hplc method for purifying peptides

Publications (3)

Publication Number Publication Date
JP2013521485A JP2013521485A (ja) 2013-06-10
JP2013521485A5 true JP2013521485A5 (enExample) 2014-04-17
JP5992836B2 JP5992836B2 (ja) 2016-09-14

Family

ID=42727392

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012555389A Expired - Fee Related JP5992836B2 (ja) 2010-03-01 2011-03-01 ペプチドを精製するための分取rp−hplc法

Country Status (5)

Country Link
US (1) US9422330B2 (enExample)
EP (1) EP2542565A1 (enExample)
JP (1) JP5992836B2 (enExample)
CN (1) CN102770440A (enExample)
WO (1) WO2011107447A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012313045A1 (en) * 2011-09-22 2014-04-10 Hochschule Ostwestfalen-Lippe Method for producing peptide fractions and use thereof
US8921113B2 (en) 2012-12-21 2014-12-30 Dionex Corporation Buffer kit and method of generating a linear pH gradient
US9724622B2 (en) 2013-01-29 2017-08-08 Neuland Health Sciences Private Limited Purification of organic compounds using surrogate stationary phases on reversed phase columns
EP2976331B1 (en) 2013-03-21 2017-03-01 Sanofi-Aventis Deutschland GmbH Synthesis of hydantoin containing peptide products
MX365465B (es) 2013-03-21 2019-06-04 Sanofi Aventis Deutschland Sintesis de productos peptidicos que contienen imida ciclica.
CA2924821A1 (en) * 2013-09-20 2015-03-26 Davuluri, Ramamohan Rao Purification of organic compounds by surfactant mediated preparative hplc
CN105223296B (zh) * 2015-10-16 2017-12-05 江苏开元药业有限公司 一类多肽的纯化方法
EP3433268B1 (en) 2016-03-23 2021-07-28 Bachem Holding AG Purification of glucagon-like peptide 1 analogs
US12269844B2 (en) 2019-03-25 2025-04-08 Scinopharm Taiwan, Ltd. Process for purifying semaglutide and liraglutide
TWI738260B (zh) 2019-03-25 2021-09-01 台灣神隆股份有限公司 純化利拉魯肽之方法
US11022585B2 (en) 2019-06-09 2021-06-01 Dionex Corporation Methods and systems for optimizing buffer conditions with liquid chromatography
KR102691149B1 (ko) 2021-01-20 2024-08-05 바이킹 테라퓨틱스 인코포레이티드 대사 및 간 질환 치료를 위한 조성물 및 방법
CN115703825B (zh) * 2021-08-17 2026-01-02 派格生物医药(杭州)股份有限公司 艾塞那肽变体及其聚乙二醇缀合物的制备方法
US12421282B2 (en) 2021-09-15 2025-09-23 Viking Therapeutics, Inc. Compositions and methods for the treatment of metabolic and liver disorders
CN114656550A (zh) * 2021-12-28 2022-06-24 深圳翰宇药业股份有限公司 一种利拉鲁肽/索马鲁肽的纯化方法及应用
WO2024147150A1 (en) * 2023-01-02 2024-07-11 Zelle Biotechnology Pvt. Ltd. Chromatographic detection, estimation and separation of amino acids in hydrolysates of monoclonal antibodies

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4028120C2 (de) * 1990-09-05 1996-09-19 Hoechst Ag Verfahren zur Reinigung von Insulin und/oder Insulinderivaten
US5424286A (en) 1993-05-24 1995-06-13 Eng; John Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
US6767887B1 (en) 1996-06-05 2004-07-27 Roche Diagnostics Gmbh Exendin analogues, processes for their preparation and medicaments containing them
CA2264243C (en) * 1996-08-30 2004-10-05 Novo Nordisk A/S Glp-1 derivatives
EP1076066A1 (en) 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptides for lowering blood glucose levels
JP2007526235A (ja) 2003-08-21 2007-09-13 ノボ ノルディスク アクティーゼルスカブ グルカゴン様ペプチドの精製
CN100535007C (zh) * 2003-08-21 2009-09-02 诺沃挪第克公司 胰高血糖素样肽的纯化
WO2007071768A1 (en) 2005-12-23 2007-06-28 Novo Nordisk A/S Purification of proteins using preparative reverse phase chromatography (rpc)
WO2007071767A1 (en) 2005-12-23 2007-06-28 Novo Nordisk Health Care Ag Purification of vitamin k-dependent polypeptides using preparative reverse phase chromatography (rpc)

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