JP2013519699A5 - - Google Patents

Info

Publication number

JP2013519699A5

JP2013519699A5 JP2012553267A JP2012553267A JP2013519699A5 JP 2013519699 A5 JP2013519699 A5 JP 2013519699A5 JP 2012553267 A JP2012553267 A JP 2012553267A JP 2012553267 A JP2012553267 A JP 2012553267A JP 2013519699 A5 JP2013519699 A5 JP 2013519699A5

Authority

JP

Japan

Prior art keywords

molecule

domain

fviii

another embodiment

receptor

Prior art date

2011-02-10

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• 102100026735 Coagulation factor VIII Human genes 0.000 claims description 38
• 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 claims description 38
• 108010054218 Factor VIII Proteins 0.000 claims description 18
• 102000001690 Factor VIII Human genes 0.000 claims description 18
• 229960000301 factor viii Drugs 0.000 claims description 18
• 230000004927 fusion Effects 0.000 claims description 17
• 108020001507 fusion proteins Proteins 0.000 claims description 13
• 102000037865 fusion proteins Human genes 0.000 claims description 13
• 108010087819 Fc receptors Proteins 0.000 claims description 11
• 102000009109 Fc receptors Human genes 0.000 claims description 11
• 108010047303 von Willebrand Factor Proteins 0.000 claims description 10
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• 102100026120 IgG receptor FcRn large subunit p51 Human genes 0.000 claims description 4
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• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 7
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