JP2013510077A5 - - Google Patents
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- Publication number
- JP2013510077A5 JP2013510077A5 JP2012535688A JP2012535688A JP2013510077A5 JP 2013510077 A5 JP2013510077 A5 JP 2013510077A5 JP 2012535688 A JP2012535688 A JP 2012535688A JP 2012535688 A JP2012535688 A JP 2012535688A JP 2013510077 A5 JP2013510077 A5 JP 2013510077A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- hydroxy
- halo
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *c(cc1)cc(*)c1-c(cc1*)ccc1C1=CC=IN=C1 Chemical compound *c(cc1)cc(*)c1-c(cc1*)ccc1C1=CC=IN=C1 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25843209P | 2009-11-05 | 2009-11-05 | |
| US61/258,432 | 2009-11-05 | ||
| PCT/EP2010/006757 WO2011054530A1 (en) | 2009-11-05 | 2010-11-05 | Gpbp inhibition using q2 peptidomimetics |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013510077A JP2013510077A (ja) | 2013-03-21 |
| JP2013510077A5 true JP2013510077A5 (enExample) | 2013-12-26 |
| JP5883794B2 JP5883794B2 (ja) | 2016-03-15 |
Family
ID=43530495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012535688A Expired - Fee Related JP5883794B2 (ja) | 2009-11-05 | 2010-11-05 | 擬似ｑ２ペプチドを用いるｇｐｂｐ抑制 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US8586776B2 (enExample) |
| EP (1) | EP2496544B1 (enExample) |
| JP (1) | JP5883794B2 (enExample) |
| CN (1) | CN102781898B (enExample) |
| ES (1) | ES2523118T3 (enExample) |
| MX (1) | MX2012005281A (enExample) |
| WO (1) | WO2011054530A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103403030A (zh) | 2011-02-21 | 2013-11-20 | 菲布他丁有限合伙公司 | 治疗和诊断疾病的方法 |
| WO2014006020A1 (en) | 2012-07-02 | 2014-01-09 | Fibrostatin, S.L. | Gpbp-1 inhibition and its therapeutic use |
| ES2489815B1 (es) * | 2013-02-21 | 2015-08-10 | Centro De Investigación Príncipe Felipe | Nuevos p-terfenilos hexakis-sustituidos con grupos bilaterales para el tratamiento de la infección por el virus de la inmunodeficiencia humana tipo 1 (VIH-1) y otras enfermedades |
| JP6322704B2 (ja) * | 2013-06-27 | 2018-05-09 | エルジー・ケム・リミテッド | Ｇｐｒ１２０アゴニストとしてのビアリール誘導体 |
| US20150093378A1 (en) * | 2013-09-27 | 2015-04-02 | Fibrostatin, S.L. | Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes |
| CN115925679A (zh) * | 2014-12-24 | 2023-04-07 | 株式会社Lg化学 | 作为gpr120激动剂的联芳基衍生物 |
| WO2016107906A1 (en) | 2014-12-31 | 2016-07-07 | Fibrostatin, S.L. | Methods for inhibiting mesenchymal phenotype after epithelial-to-mesenchymal transition |
| WO2017134146A1 (en) * | 2016-02-02 | 2017-08-10 | Fibrostatin, S.L. | Gpbp inhibitors and uses and scaleable synthesis thereof |
| CN112479941B (zh) * | 2020-11-30 | 2023-01-13 | 沧州维智达美制药有限公司 | 一种2-取代-3-芳基卤苄衍生物的制备方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5723500A (en) * | 1995-09-22 | 1998-03-03 | Colgate-Palmolive Company | Antiplaque oral composition and method |
| PT933346E (pt) * | 1996-07-31 | 2004-03-31 | Shionogi & Co | Novos compostos de p-terfenilo |
| ES2202663T3 (es) * | 1996-12-11 | 2004-04-01 | ABBOTT GMBH & CO. KG | Cetobenzamidas como inhibidores de calpaina. |
| ATE316577T1 (de) | 1999-02-24 | 2006-02-15 | Juan Saus | Das goodpasture-antigen bindende protein |
| US6881547B1 (en) | 2001-01-31 | 2005-04-19 | Juan Saus | Methods and reagents for treating autoimmune disorders |
| DE60229059D1 (de) * | 2001-05-08 | 2008-11-06 | Univ Yale | Proteomimetische verbindungen und verfahren |
| WO2004070025A2 (en) | 2003-02-05 | 2004-08-19 | Juan Saus | Novel goodpasture antigen-binding protein isoforms and protein misfolded-mediated disorders |
| WO2004071426A2 (en) * | 2003-02-11 | 2004-08-26 | Kemia Inc. | Compounds for the treatment of viral infection |
| US7279600B2 (en) * | 2003-05-02 | 2007-10-09 | Wyeth | Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents |
| GB0416508D0 (en) * | 2004-07-23 | 2004-08-25 | Merck Sharp & Dohme | Therapeutic agents |
| GB0500784D0 (en) * | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
| JP4776279B2 (ja) * | 2005-06-09 | 2011-09-21 | 株式会社Ａｄｅｋａ | 新規化合物及び液晶組成物 |
| CN101268029B (zh) * | 2005-10-07 | 2012-09-05 | 三菱化学株式会社 | 烃化合物、电荷传输材料、电荷传输材料组合物和有机电致发光元件 |
| JP5209325B2 (ja) * | 2006-01-25 | 2013-06-12 | 保土谷化学工業株式会社 | ｐ−ターフェニル化合物混合物及び該化合物混合物を用いた電子写真用感光体 |
| WO2009008311A1 (ja) * | 2007-07-07 | 2009-01-15 | Idemitsu Kosan Co., Ltd. | クリセン誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
| EA201070422A1 (ru) * | 2007-10-04 | 2010-12-30 | Мерк Сероно С.А. | Производные оксадиазола |
| BRPI0817433A2 (pt) * | 2007-10-19 | 2015-06-16 | Janssen Pharmaceutica Nv | Moduladores de gama-secretase piperidinila e piperazinila |
| JP5662803B2 (ja) * | 2007-12-20 | 2015-02-04 | アストラゼネカ アクチボラグ | Ｄｇａｔ１阻害剤としてのカルバモイル化合物１９０ |
-
2010
- 2010-11-05 US US12/940,598 patent/US8586776B2/en not_active Expired - Fee Related
- 2010-11-05 WO PCT/EP2010/006757 patent/WO2011054530A1/en not_active Ceased
- 2010-11-05 JP JP2012535688A patent/JP5883794B2/ja not_active Expired - Fee Related
- 2010-11-05 MX MX2012005281A patent/MX2012005281A/es active IP Right Grant
- 2010-11-05 ES ES10779469.5T patent/ES2523118T3/es active Active
- 2010-11-05 CN CN201080050226.2A patent/CN102781898B/zh active Active
- 2010-11-05 EP EP10779469.5A patent/EP2496544B1/en active Active
-
2013
- 2013-10-25 US US14/063,709 patent/US9199936B2/en not_active Expired - Fee Related
-
2015
- 2015-11-18 US US14/944,721 patent/US20160083327A1/en not_active Abandoned
-
2018
- 2018-02-08 US US15/892,317 patent/US10544083B2/en not_active Expired - Fee Related
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