JP2013516480A5 - - Google Patents
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- Publication number
- JP2013516480A5 JP2013516480A5 JP2012548127A JP2012548127A JP2013516480A5 JP 2013516480 A5 JP2013516480 A5 JP 2013516480A5 JP 2012548127 A JP2012548127 A JP 2012548127A JP 2012548127 A JP2012548127 A JP 2012548127A JP 2013516480 A5 JP2013516480 A5 JP 2013516480A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- compound
- cancer
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29312810P | 2010-01-07 | 2010-01-07 | |
| US61/293,128 | 2010-01-07 | ||
| PCT/US2011/020416 WO2011085128A1 (en) | 2010-01-07 | 2011-01-06 | Hedgehog inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013516480A JP2013516480A (ja) | 2013-05-13 |
| JP2013516480A5 true JP2013516480A5 (enExample) | 2014-02-27 |
Family
ID=44305789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012548127A Pending JP2013516480A (ja) | 2010-01-07 | 2011-01-06 | ヘッジホッグ阻害剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9174949B2 (enExample) |
| EP (1) | EP2521451A4 (enExample) |
| JP (1) | JP2013516480A (enExample) |
| KR (1) | KR20120099155A (enExample) |
| CN (1) | CN102802419A (enExample) |
| AU (1) | AU2011204370B2 (enExample) |
| CA (1) | CA2785204C (enExample) |
| MX (1) | MX2012007929A (enExample) |
| PH (1) | PH12012501389A1 (enExample) |
| WO (1) | WO2011085128A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9187485B2 (en) | 2007-02-02 | 2015-11-17 | Baylor College Of Medicine | Methods and compositions for the treatment of cancer and related hyperproliferative disorders |
| AU2011204370B2 (en) | 2010-01-07 | 2015-03-05 | Selexagen Therapeutics, Inc. | Hedgehog inhibitors |
| WO2014043715A1 (en) * | 2012-09-17 | 2014-03-20 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| JP2016534124A (ja) * | 2013-08-29 | 2016-11-04 | ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ | 代謝並びに体重関連疾患の処置のための組成物および方法 |
| WO2015073691A1 (en) | 2013-11-14 | 2015-05-21 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treating cancer by activation of bmp signaling |
| WO2017156350A1 (en) | 2016-03-09 | 2017-09-14 | K-Gen, Inc. | Methods of cancer treatment |
| US10548908B2 (en) * | 2016-09-15 | 2020-02-04 | Nostopharma, LLC | Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification |
| US10521327B2 (en) * | 2016-09-29 | 2019-12-31 | 2236008 Ontario Inc. | Non-coupled software lockstep |
| CN111263756B (zh) * | 2017-07-11 | 2023-05-16 | 赛泰尔治疗公司 | Rad51抑制剂 |
| WO2025232650A1 (zh) * | 2024-05-07 | 2025-11-13 | 南京同诺康医药科技有限公司 | Kif18a抑制剂及其制备方法和用途 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6362369B2 (en) * | 1997-11-25 | 2002-03-26 | Nihon Nohyaku Co., Ltd. | Phthalic acid diamide derivatives fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides |
| US6552016B1 (en) | 1999-10-14 | 2003-04-22 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| PA8557501A1 (es) | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
| SI1725544T1 (sl) | 2004-03-09 | 2009-10-31 | Boehringer Ingelheim Pharma | 3-(4-heterociklil-1,2,3-triazol-1-il)-N-aril-benzamidi kot inhibitorji proizvodnje citokinov za zdravljenje kroničnih vnetnih bolezni |
| WO2005108370A1 (ja) * | 2004-04-16 | 2005-11-17 | Ajinomoto Co., Inc. | ベンゼン化合物 |
| KR20150002863A (ko) | 2004-09-02 | 2015-01-07 | 제넨테크, 인크. | 헤지호그 신호전달에 대한 피리딜 억제제 |
| RU2007119637A (ru) | 2004-10-28 | 2008-12-10 | Айрм Ллк (Bm) | Соединения и композиции в качестве модуляторов hedgehog-пути |
| EP1957461B1 (en) | 2005-11-14 | 2016-11-02 | Genentech, Inc. | Bisamide inhibitors of hedgehog signaling |
| PE20080948A1 (es) | 2006-07-25 | 2008-09-10 | Irm Llc | Derivados de imidazol como moduladores de la senda de hedgehog |
| TW200918521A (en) * | 2007-08-31 | 2009-05-01 | Astrazeneca Ab | Heterocyclic amides and methods of use thereof |
| TW200916458A (en) * | 2007-09-05 | 2009-04-16 | Astrazeneca Ab | Heterocyclic compounds and methods of use thereof |
| WO2009151495A2 (en) * | 2008-03-18 | 2009-12-17 | Amgen Inc. | Oxazole compounds, compositions and methods of use |
| WO2009146013A1 (en) * | 2008-03-31 | 2009-12-03 | Georgetown University | Myosin light chain phosphatase inhibitors |
| WO2010127152A2 (en) * | 2009-04-29 | 2010-11-04 | Irm Llc | Compounds and compositions as microsomal prostaglandin e synthase-1 inhibitors |
| WO2011014888A1 (en) | 2009-07-31 | 2011-02-03 | Selexagen Therapeutics | Novel hedgehog inhibitors |
| AU2011204370B2 (en) | 2010-01-07 | 2015-03-05 | Selexagen Therapeutics, Inc. | Hedgehog inhibitors |
| WO2011085261A1 (en) | 2010-01-08 | 2011-07-14 | Selexagen Therapeutics, Inc. | Hedgehog inhibitors |
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2011
- 2011-01-06 AU AU2011204370A patent/AU2011204370B2/en not_active Ceased
- 2011-01-06 PH PH1/2012/501389A patent/PH12012501389A1/en unknown
- 2011-01-06 KR KR20127020162A patent/KR20120099155A/ko not_active Withdrawn
- 2011-01-06 MX MX2012007929A patent/MX2012007929A/es active IP Right Grant
- 2011-01-06 CN CN2011800055507A patent/CN102802419A/zh active Pending
- 2011-01-06 US US13/520,150 patent/US9174949B2/en not_active Expired - Fee Related
- 2011-01-06 WO PCT/US2011/020416 patent/WO2011085128A1/en not_active Ceased
- 2011-01-06 JP JP2012548127A patent/JP2013516480A/ja active Pending
- 2011-01-06 EP EP20110732162 patent/EP2521451A4/en not_active Withdrawn
- 2011-01-06 CA CA2785204A patent/CA2785204C/en not_active Expired - Fee Related