JP2013506837A5 - - Google Patents
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- Publication number
- JP2013506837A5 JP2013506837A5 JP2012532147A JP2012532147A JP2013506837A5 JP 2013506837 A5 JP2013506837 A5 JP 2013506837A5 JP 2012532147 A JP2012532147 A JP 2012532147A JP 2012532147 A JP2012532147 A JP 2012532147A JP 2013506837 A5 JP2013506837 A5 JP 2013506837A5
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- JP
- Japan
- Prior art keywords
- test sample
- contacted
- target antigens
- target
- antigens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims description 45
- 239000000427 antigen Substances 0.000 claims description 40
- 102000036639 antigens Human genes 0.000 claims description 38
- 108091007433 antigens Proteins 0.000 claims description 38
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 claims description 16
- 208000033222 Biliary cirrhosis primary Diseases 0.000 claims description 16
- 208000012654 Primary biliary cholangitis Diseases 0.000 claims description 16
- 210000001124 body fluid Anatomy 0.000 claims description 5
- 239000010839 body fluid Substances 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 4
- 210000002381 plasma Anatomy 0.000 claims description 4
- 210000002966 serum Anatomy 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 102100030338 Hexokinase-1 Human genes 0.000 claims 4
- 101710198391 Hexokinase-1 Proteins 0.000 claims 4
- 239000012634 fragment Substances 0.000 description 8
- 238000003018 immunoassay Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24876809P | 2009-10-05 | 2009-10-05 | |
| US61/248,768 | 2009-10-05 | ||
| PCT/US2010/051475 WO2011044125A1 (en) | 2009-10-05 | 2010-10-05 | A method for diagnosing primary biliary cirrhosis (pbc) using novel autoantigens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015041977A Division JP6012794B2 (ja) | 2009-10-05 | 2015-03-04 | 自己抗原を使用する原発性胆汁性肝硬変（ｐｂｃ）を診断するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013506837A JP2013506837A (ja) | 2013-02-28 |
| JP2013506837A5 true JP2013506837A5 (enExample) | 2013-10-17 |
| JP5710623B2 JP5710623B2 (ja) | 2015-04-30 |
Family
ID=43857083
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012532147A Active JP5710623B2 (ja) | 2009-10-05 | 2010-10-05 | 自己抗原を使用する原発性胆汁性肝硬変（ｐｂｃ）を診断するための方法 |
| JP2015041977A Active JP6012794B2 (ja) | 2009-10-05 | 2015-03-04 | 自己抗原を使用する原発性胆汁性肝硬変（ｐｂｃ）を診断するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015041977A Active JP6012794B2 (ja) | 2009-10-05 | 2015-03-04 | 自己抗原を使用する原発性胆汁性肝硬変（ｐｂｃ）を診断するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US8852956B2 (enExample) |
| EP (2) | EP2486407B1 (enExample) |
| JP (2) | JP5710623B2 (enExample) |
| AU (2) | AU2010303628B2 (enExample) |
| CA (2) | CA2965189C (enExample) |
| ES (2) | ES2681839T3 (enExample) |
| WO (1) | WO2011044125A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2486407B1 (en) * | 2009-10-05 | 2016-02-10 | Ambergen Inc. | A method for diagnosing primary biliary cirrhosis (pbc) using novel autoantigens |
| CN102627695B (zh) * | 2012-03-23 | 2014-10-22 | 中国医学科学院北京协和医院 | 原发性胆汁性肝硬化特异性自身抗原及其应用 |
| CN104292322A (zh) * | 2012-03-23 | 2015-01-21 | 中国医学科学院北京协和医院 | 原发性胆汁性肝硬化特异性自身抗原及其应用 |
| CN104292323B (zh) * | 2012-03-23 | 2017-04-05 | 中国医学科学院北京协和医院 | 原发性胆汁性肝硬化特异性自身抗原及其应用 |
| US12442818B2 (en) | 2019-03-15 | 2025-10-14 | Cz Biohub Sf, Llc | Autoantibodies as biomarker of paraneoplastic encephalitis associated with testicular cancer |
| CN116113832A (zh) * | 2021-01-08 | 2023-05-12 | 依诺瓦诊断公司 | 用于诊断原发性胆汁性肝硬化的组合物和方法 |
| CN113009148A (zh) * | 2021-02-10 | 2021-06-22 | 中国医学科学院北京协和医院 | 用于诊断抗sp100抗体阳性与阴性pbc患者的糖链标志物及其用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4208479A (en) * | 1977-07-14 | 1980-06-17 | Syva Company | Label modified immunoassays |
| ZA879403B (en) * | 1986-12-16 | 1988-06-23 | Amrad Corp Ltd | Primary biliary cirrhosis autoantigen |
| JPH03291568A (ja) * | 1990-04-09 | 1991-12-20 | Igaku Seibutsugaku Kenkyusho:Kk | 抗ミトコンドリアｍ↓２抗体の検出用試薬及び測定法 |
| JP3472048B2 (ja) * | 1995-10-09 | 2003-12-02 | 鐘淵化学工業株式会社 | 自己免疫疾患の診断薬 |
| AU717738B2 (en) * | 1996-06-24 | 2000-03-30 | Ross Coppel | Recombinant fusion protein comprising PDC-E2, BCOADC-E2, and OGDC-E2 and uses thereof |
| JPH1138008A (ja) * | 1997-07-16 | 1999-02-12 | Sumitomo Electric Ind Ltd | 自己抗体の検出方法および検出試薬 |
| US7087717B2 (en) * | 2000-07-24 | 2006-08-08 | The General Hospital Corporation | Sp110, a polypeptide component of the nuclear body |
| AU2002254431A1 (en) * | 2001-03-27 | 2002-10-08 | M. Eric Gershwin | Antibodies against autoantigens of primary biliary cirrhosis and methods of making and using them |
| ES2334149T3 (es) * | 2004-01-21 | 2010-03-05 | Gilead Sciences, Inc. | Uso de adefovir o tenofovir para inhibir virus de tipo vtmr implicados en el cancer de mama y en la cirrosis biliar primaria. |
| JP2006071409A (ja) * | 2004-09-01 | 2006-03-16 | Kansai Tlo Kk | シェーグレン症候群診断キット |
| WO2007043103A1 (ja) * | 2005-09-30 | 2007-04-19 | Kansai Technology Licensing Organization Co., Ltd. | シェーグレン症候群診断法及び診断キット |
| JP2007245505A (ja) | 2006-03-15 | 2007-09-27 | Fujifilm Corp | 平版印刷版原版、平版印刷版およびその作製方法 |
| US20090047689A1 (en) * | 2007-06-20 | 2009-02-19 | John Kolman | Autoantigen biomarkers for early diagnosis of lung adenocarcinoma |
| JP5471724B2 (ja) | 2009-09-30 | 2014-04-16 | 大日本印刷株式会社 | 化粧シート |
| EP2486407B1 (en) * | 2009-10-05 | 2016-02-10 | Ambergen Inc. | A method for diagnosing primary biliary cirrhosis (pbc) using novel autoantigens |
| JP2012206482A (ja) | 2011-03-30 | 2012-10-25 | Daikyonishikawa Corp | 樹脂成形品の組付け構造 |
-
2010
- 2010-10-05 EP EP10822527.7A patent/EP2486407B1/en active Active
- 2010-10-05 CA CA2965189A patent/CA2965189C/en active Active
- 2010-10-05 CA CA2776688A patent/CA2776688C/en active Active
- 2010-10-05 JP JP2012532147A patent/JP5710623B2/ja active Active
- 2010-10-05 EP EP15194007.9A patent/EP3012631B1/en active Active
- 2010-10-05 WO PCT/US2010/051475 patent/WO2011044125A1/en not_active Ceased
- 2010-10-05 ES ES15194007.9T patent/ES2681839T3/es active Active
- 2010-10-05 US US13/500,411 patent/US8852956B2/en active Active
- 2010-10-05 AU AU2010303628A patent/AU2010303628B2/en active Active
- 2010-10-05 ES ES10822527.7T patent/ES2566762T3/es active Active
-
2014
- 2014-06-27 US US14/318,498 patent/US20150057170A1/en not_active Abandoned
-
2015
- 2015-03-04 JP JP2015041977A patent/JP6012794B2/ja active Active
- 2015-10-07 AU AU2015238816A patent/AU2015238816B2/en active Active
-
2017
- 2017-03-24 US US15/469,350 patent/US11885802B2/en active Active
-
2023
- 2023-11-28 US US18/522,114 patent/US20240159749A1/en active Pending
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