JP2011521216A5 - - Google Patents

Info

Publication number

JP2011521216A5

JP2011521216A5 JP2011508900A JP2011508900A JP2011521216A5 JP 2011521216 A5 JP2011521216 A5 JP 2011521216A5 JP 2011508900 A JP2011508900 A JP 2011508900A JP 2011508900 A JP2011508900 A JP 2011508900A JP 2011521216 A5 JP2011521216 A5 JP 2011521216A5

Authority

JP

Japan

Prior art keywords

antibody

marker

autoantigen

biological sample

subject

Prior art date

2009-05-12

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 238000000034 method Methods 0.000 claims description 11
• 239000012472 biological sample Substances 0.000 claims description 10
• 239000003153 chemical reaction reagent Substances 0.000 claims description 9
• 230000015572 biosynthetic process Effects 0.000 claims description 3
• 239000007787 solid Substances 0.000 claims description 3
• 238000001514 detection method Methods 0.000 claims description 2
• 238000003018 immunoassay Methods 0.000 claims description 2
• 101000984753 Homo sapiens Serine/threonine-protein kinase B-raf Proteins 0.000 claims 7
• 102100027103 Serine/threonine-protein kinase B-raf Human genes 0.000 claims 7
• 230000003197 catalytic effect Effects 0.000 claims 7
• 239000012634 fragment Substances 0.000 claims 7
• 206010039073 rheumatoid arthritis Diseases 0.000 claims 6
• 101100406797 Arabidopsis thaliana PAD4 gene Proteins 0.000 claims 3
• 101150094373 Padi4 gene Proteins 0.000 claims 3
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• 150000001413 amino acids Chemical class 0.000 claims 2
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 108010074051 C-Reactive Protein Proteins 0.000 claims 1
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• 102000004889 Interleukin-6 Human genes 0.000 claims 1
• 108090001005 Interleukin-6 Proteins 0.000 claims 1
• 102000005482 Lipopolysaccharide Receptors Human genes 0.000 claims 1
• 108010031801 Lipopolysaccharide Receptors Proteins 0.000 claims 1
• 102000000380 Matrix Metalloproteinase 1 Human genes 0.000 claims 1
• 108010016113 Matrix Metalloproteinase 1 Proteins 0.000 claims 1
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• 102000004264 Osteopontin Human genes 0.000 claims 1
• 108010081689 Osteopontin Proteins 0.000 claims 1
• 102000013674 S-100 Human genes 0.000 claims 1
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