JP2015500502A5 - - Google Patents
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- Publication number
- JP2015500502A5 JP2015500502A5 JP2014547447A JP2014547447A JP2015500502A5 JP 2015500502 A5 JP2015500502 A5 JP 2015500502A5 JP 2014547447 A JP2014547447 A JP 2014547447A JP 2014547447 A JP2014547447 A JP 2014547447A JP 2015500502 A5 JP2015500502 A5 JP 2015500502A5
- Authority
- JP
- Japan
- Prior art keywords
- conductivity
- sodium chloride
- chloride solution
- autoantibody
- biological sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 198
- 238000000034 method Methods 0.000 claims description 159
- 239000011780 sodium chloride Substances 0.000 claims description 99
- 239000000243 solution Substances 0.000 claims description 99
- 239000012472 biological sample Substances 0.000 claims description 62
- 239000000427 antigen Substances 0.000 claims description 37
- 102000036639 antigens Human genes 0.000 claims description 37
- 108091007433 antigens Proteins 0.000 claims description 37
- 241000894007 species Species 0.000 claims description 28
- 102000013455 Amyloid beta-Peptides Human genes 0.000 claims description 22
- 108010090849 Amyloid beta-Peptides Proteins 0.000 claims description 22
- 239000013024 dilution buffer Substances 0.000 claims description 20
- 239000007790 solid phase Substances 0.000 claims description 18
- 239000011534 wash buffer Substances 0.000 claims description 15
- 108020004414 DNA Proteins 0.000 claims description 14
- 230000027455 binding Effects 0.000 claims description 12
- 102000009843 Thyroglobulin Human genes 0.000 claims description 8
- 108010034949 Thyroglobulin Proteins 0.000 claims description 8
- 102000004243 Tubulin Human genes 0.000 claims description 8
- 108090000704 Tubulin Proteins 0.000 claims description 8
- 210000004369 blood Anatomy 0.000 claims description 8
- 239000008280 blood Substances 0.000 claims description 8
- 210000002381 plasma Anatomy 0.000 claims description 8
- 210000002966 serum Anatomy 0.000 claims description 8
- 229960002175 thyroglobulin Drugs 0.000 claims description 8
- 238000001990 intravenous administration Methods 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 7
- 102000003992 Peroxidases Human genes 0.000 claims description 6
- 239000003153 chemical reaction reagent Substances 0.000 claims description 6
- 238000001514 detection method Methods 0.000 claims description 6
- 108040007629 peroxidase activity proteins Proteins 0.000 claims description 6
- 230000009870 specific binding Effects 0.000 claims description 6
- 238000005406 washing Methods 0.000 claims description 6
- 102000053602 DNA Human genes 0.000 claims description 4
- 108020004682 Single-Stranded DNA Proteins 0.000 claims description 2
- 239000000539 dimer Substances 0.000 claims description 2
- 239000000178 monomer Substances 0.000 claims description 2
- 239000000872 buffer Substances 0.000 description 2
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 210000001179 synovial fluid Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161570211P | 2011-12-13 | 2011-12-13 | |
| US61/570,211 | 2011-12-13 | ||
| PCT/US2012/069587 WO2013090636A1 (en) | 2011-12-13 | 2012-12-13 | Measurement of autoantibodies at low conductivity conditions with increased sensitivity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015500502A JP2015500502A (ja) | 2015-01-05 |
| JP2015500502A5 true JP2015500502A5 (enExample) | 2016-02-04 |
| JP6333731B2 JP6333731B2 (ja) | 2018-05-30 |
Family
ID=47630506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014547447A Active JP6333731B2 (ja) | 2011-12-13 | 2012-12-13 | 低伝導率条件下の高感度を有する自己抗体測定法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9075069B2 (enExample) |
| EP (1) | EP2791675B1 (enExample) |
| JP (1) | JP6333731B2 (enExample) |
| KR (1) | KR20140104479A (enExample) |
| AR (1) | AR089233A1 (enExample) |
| AU (1) | AU2012321074B2 (enExample) |
| DK (1) | DK2791675T3 (enExample) |
| ES (1) | ES2685332T3 (enExample) |
| HR (1) | HRP20181118T1 (enExample) |
| HU (1) | HUE038441T2 (enExample) |
| PL (1) | PL2791675T3 (enExample) |
| PT (1) | PT2791675T (enExample) |
| TW (1) | TW201339578A (enExample) |
| WO (1) | WO2013090636A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11255863B2 (en) | 2016-03-16 | 2022-02-22 | Peoplebio, Inc. | Method for detecting aggregate of aggregate-forming polypeptide |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013203043B2 (en) | 2013-03-15 | 2016-10-06 | Takeda Pharmaceutical Company Limited | Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs |
| US20160168235A1 (en) * | 2013-07-19 | 2016-06-16 | Board Of Regents Of The University Of Texas System | Transthyretin amyloid-selective and polyreactive catabodies |
| SI24638A (sl) | 2014-02-04 | 2015-08-31 | Univerzitetni kliniÄŤni center Ljubljana | Fluorometrična imunska metoda za določanje protiteles proti dvojnoverižni DNA |
| RU2017107273A (ru) * | 2014-08-08 | 2018-09-10 | Аллегени-Сингер Рисерч Инститьют | Антилимфоцитарные аутоантитела в качестве диагностических биомаркеров |
| EP3329278A4 (en) | 2015-07-31 | 2019-01-16 | Allegheny-Singer Research Institute | CELL-ASSOCIATED COMPLEMENT ACTIVATION PRODUCTS AS COMPARATIVE DIAGNOSTICS FOR ANTIBODY-BASED MEDICAMENTS |
| CN108169303B (zh) * | 2017-12-07 | 2019-08-20 | 商丘师范学院 | 基于金属有机框架材料作为信号探针的核酸适配体电化学传感器 |
| US12436148B2 (en) | 2018-07-02 | 2025-10-07 | Siemens Healthcare Diagnostics Inc. | Direct immunoassay measurement of autoantibodies |
| JP7268306B2 (ja) * | 2018-08-31 | 2023-05-08 | 東洋紡株式会社 | 生体試料中の測定対象物質を免疫学的に測定する方法 |
| JP7356128B2 (ja) * | 2019-06-07 | 2023-10-04 | 慶應義塾 | 自己免疫疾患の検出剤となるタンパク質複合体、及びその使用 |
| CN113759107A (zh) * | 2021-08-18 | 2021-12-07 | 苏州立禾生物医学工程有限公司 | 生物素标记缓冲液 |
| CN117347616A (zh) * | 2022-06-27 | 2024-01-05 | 菲鹏生物股份有限公司 | 稀释剂、捕获试剂、检测试剂盒和测定方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4259207A (en) | 1979-09-19 | 1981-03-31 | American Hospital Supply Corporation | Suspending medium for immunologic reactions |
| JPS57182168A (en) * | 1981-05-02 | 1982-11-09 | Mitsubishi Chem Ind Ltd | Immunochemical reagent |
| US5183735A (en) * | 1989-02-27 | 1993-02-02 | Reaads Medical Products, Inc. | Method and diagnostic test kit for detection of anti-dsDNA antibodies |
| US5194585A (en) * | 1989-04-25 | 1993-03-16 | Igen, Inc. | Inhibitors of catalytic antibodies |
| US5981180A (en) | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
| US5763158A (en) | 1997-02-06 | 1998-06-09 | The United States Of America As Represented By The Secretary Of The Army | Detection of multiple antigens or antibodies |
| US6958244B2 (en) * | 2002-04-12 | 2005-10-25 | Bruker Biospin Corp. | Low-conductivity buffers for magnetic resonance measurements |
| ES2661168T3 (es) * | 2003-07-12 | 2018-03-27 | Accelerate Diagnostics, Inc. | Biodetección sensible y rápida |
| AU2008286361B2 (en) | 2007-08-13 | 2013-09-26 | Takeda Pharmaceutical Company Limited | IVIG modulation of chemokines for treatment of multiple sclerosis, Alzheimer's disease, and Parkinson's disease |
| US8852874B2 (en) | 2008-02-29 | 2014-10-07 | Baxter International Inc. | Anti-amyloid β activity of intravenous immunoglobulin (IVIG) in vitro |
| CN102341707B (zh) * | 2009-03-05 | 2014-05-07 | 电化生研株式会社 | 检测试剂以及使用该检测试剂测定检测样品中的被测定物的方法 |
| CN102449483A (zh) * | 2009-03-31 | 2012-05-09 | 日本烟草产业株式会社 | 对生物学样品中的sith-1抗体进行检测的方法 |
| US8546548B2 (en) | 2009-05-27 | 2013-10-01 | Baxter International Inc. | Method to produce a highly concentrated immunoglobulin preparation for subcutaneous use |
| AU2010202125B1 (en) | 2010-05-26 | 2010-09-02 | Takeda Pharmaceutical Company Limited | A method to produce an immunoglobulin preparation with improved yield |
-
2012
- 2012-12-13 WO PCT/US2012/069587 patent/WO2013090636A1/en not_active Ceased
- 2012-12-13 HR HRP20181118TT patent/HRP20181118T1/hr unknown
- 2012-12-13 KR KR1020147019006A patent/KR20140104479A/ko not_active Withdrawn
- 2012-12-13 TW TW101147349A patent/TW201339578A/zh unknown
- 2012-12-13 US US13/714,309 patent/US9075069B2/en active Active
- 2012-12-13 PL PL12820994T patent/PL2791675T3/pl unknown
- 2012-12-13 ES ES12820994.7T patent/ES2685332T3/es active Active
- 2012-12-13 AR ARP120104707A patent/AR089233A1/es unknown
- 2012-12-13 DK DK12820994.7T patent/DK2791675T3/da active
- 2012-12-13 EP EP12820994.7A patent/EP2791675B1/en active Active
- 2012-12-13 HU HUE12820994A patent/HUE038441T2/hu unknown
- 2012-12-13 JP JP2014547447A patent/JP6333731B2/ja active Active
- 2012-12-13 AU AU2012321074A patent/AU2012321074B2/en active Active
- 2012-12-13 PT PT128209947T patent/PT2791675T/pt unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11255863B2 (en) | 2016-03-16 | 2022-02-22 | Peoplebio, Inc. | Method for detecting aggregate of aggregate-forming polypeptide |
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