JP2017531801A5 - - Google Patents
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- Publication number
- JP2017531801A5 JP2017531801A5 JP2017518834A JP2017518834A JP2017531801A5 JP 2017531801 A5 JP2017531801 A5 JP 2017531801A5 JP 2017518834 A JP2017518834 A JP 2017518834A JP 2017518834 A JP2017518834 A JP 2017518834A JP 2017531801 A5 JP2017531801 A5 JP 2017531801A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- cdtb
- level
- vinculin
- ibs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 43
- 208000002551 irritable bowel syndrome Diseases 0.000 claims description 31
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims description 25
- 208000015943 Coeliac disease Diseases 0.000 claims description 21
- 239000012472 biological sample Substances 0.000 claims description 20
- 238000002965 ELISA Methods 0.000 claims description 8
- 241000589875 Campylobacter jejuni Species 0.000 claims description 4
- 102000003970 Vinculin Human genes 0.000 claims description 4
- 108090000384 Vinculin Proteins 0.000 claims description 4
- 238000001261 affinity purification Methods 0.000 claims description 4
- 210000004369 blood Anatomy 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 4
- 238000000684 flow cytometry Methods 0.000 claims description 4
- 238000003364 immunohistochemistry Methods 0.000 claims description 4
- 238000007901 in situ hybridization Methods 0.000 claims description 4
- 238000005259 measurement Methods 0.000 claims description 4
- 230000003287 optical effect Effects 0.000 claims description 4
- 210000002381 plasma Anatomy 0.000 claims description 4
- 238000003127 radioimmunoassay Methods 0.000 claims description 4
- 210000002966 serum Anatomy 0.000 claims description 4
- 238000003745 diagnosis Methods 0.000 description 11
- 238000010187 selection method Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462061877P | 2014-10-09 | 2014-10-09 | |
| US62/061,877 | 2014-10-09 | ||
| US201462085825P | 2014-12-01 | 2014-12-01 | |
| US62/085,825 | 2014-12-01 | ||
| PCT/US2015/054655 WO2016057772A1 (en) | 2014-10-09 | 2015-10-08 | Methods and systems for distinguishing irritable bowel syndrome from inflammatory bowel disease and celiac disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531801A JP2017531801A (ja) | 2017-10-26 |
| JP2017531801A5 true JP2017531801A5 (enExample) | 2017-12-07 |
| JP6784669B2 JP6784669B2 (ja) | 2020-11-11 |
Family
ID=55653760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017518834A Active JP6784669B2 (ja) | 2014-10-09 | 2015-10-08 | 炎症性腸疾患及びセリアック病から過敏性腸症候群を識別するための方法及びシステム |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10132814B2 (enExample) |
| EP (1) | EP3204771B1 (enExample) |
| JP (1) | JP6784669B2 (enExample) |
| KR (1) | KR102426541B1 (enExample) |
| CN (1) | CN107003308B (enExample) |
| AU (1) | AU2015330872B2 (enExample) |
| CA (1) | CA2962493C (enExample) |
| ES (1) | ES3028294T3 (enExample) |
| IL (1) | IL251606B (enExample) |
| MX (1) | MX384921B (enExample) |
| NZ (1) | NZ730490A (enExample) |
| PL (1) | PL3204771T3 (enExample) |
| PT (1) | PT3204771T (enExample) |
| RU (1) | RU2706361C2 (enExample) |
| SG (1) | SG11201702395WA (enExample) |
| WO (1) | WO2016057772A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9110081B2 (en) | 2009-02-11 | 2015-08-18 | Cedars-Sinai Medical Center | Antibody to cytolethal distending toxin of Campylobacter jejuni |
| US11693009B2 (en) | 2009-02-11 | 2023-07-04 | Cedars-Sinai Medical Center | Methods for detecting post-infectious irritable bowel syndrome |
| US9702884B2 (en) | 2012-09-17 | 2017-07-11 | Cedars-Sinai Medical Center | Methods for detecting the presence of irritable bowel syndrome and system for diagnosing same |
| NZ717633A (en) | 2013-10-09 | 2021-07-30 | Cedars Sinai Medical Center | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
| CN107003308B (zh) | 2014-10-09 | 2020-02-11 | 西达-赛奈医疗中心 | 用于区分肠易激综合征与炎性肠病和乳糜泻的方法和系统 |
| EP3573650A4 (en) | 2017-01-30 | 2020-12-09 | Cedars-Sinai Medical Center | DIAGNOSIS OF SCLERODERMIA |
| EP3913371A1 (en) | 2020-05-18 | 2021-11-24 | Neuroimmun GmbH | Method and kit for diagnosting irritable bowel syndrome and for its relief through dietary interventions |
| CN114895025B (zh) * | 2021-07-01 | 2025-08-12 | 浙江大学 | 一种检测抗粘着斑蛋白-IgG抗体的试剂盒 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5691151A (en) | 1994-10-07 | 1997-11-25 | Regents Of University Of California | Methods of screening for ulcerative colitis and crohn's disease by detecting VH3-15 autoantibody and panca |
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| US6562629B1 (en) | 1999-08-11 | 2003-05-13 | Cedars-Sinai Medical Center | Method of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth by detecting the presence of anti-saccharomyces cerivisiae antibodies (asca) in human serum |
| FR2806805A1 (fr) | 2000-03-22 | 2001-09-28 | Centre Nat Rech Scient | SEQUENCE PEPTIDIQUES COMPRENANT UN OU PLUSIEURS MOTIFS DE LIAISON AUX PROTEINES DE LA FAMILLE Ena/VASP, ET LEURS UTILISATIONS |
| AU2003233576A1 (en) | 2002-05-17 | 2003-12-02 | Sugen, Inc. | Novel biomarkers of tyrosine kinase inhibitor exposure and activity in mammals |
| AU2003291625B2 (en) | 2002-09-16 | 2009-10-08 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US7595386B2 (en) | 2003-01-24 | 2009-09-29 | William Beaumont Hospital | Methods and compositions for heat activated gene therapy using cytolethal distending toxin |
| JP2006522817A (ja) * | 2003-04-08 | 2006-10-05 | プロジェニックス ファーマシューティカルズ，インコーポレーテッド | 過敏性腸症候群を処置するための末梢オピオイドアンタゴニスト、特にメチルナルトレキソンの使用 |
| EP2280286A1 (en) | 2003-09-15 | 2011-02-02 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate systemic lupus erythematosus |
| CN1914322B (zh) | 2003-12-05 | 2012-05-30 | 扶桑药品工业株式会社 | 细胞致死肿胀毒素及以其为目标的弯曲杆菌属细菌的检测 |
| US20080085524A1 (en) | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
| EP2102367A2 (en) | 2006-11-09 | 2009-09-23 | XDX, Inc. | Methods for diagnosing and monitoring the status of systemic lupus erythematosus |
| CA2747253A1 (en) | 2007-12-20 | 2009-07-02 | Index Diagnostics Ab | Method and kit for use in the differentiation of ibd and ibs and further distinction between disease types of ibd |
| WO2010045180A1 (en) | 2008-10-13 | 2010-04-22 | Metabolon, Inc. | Biomarkers for inflammatory bowel disease and methods using the same |
| JP5564512B2 (ja) | 2008-11-24 | 2014-07-30 | セダーズ−シナイ メディカル センター | 抗酸化カンプトセシン誘導体及びその抗酸化、抗新生物ナノスフェア |
| US9110081B2 (en) | 2009-02-11 | 2015-08-18 | Cedars-Sinai Medical Center | Antibody to cytolethal distending toxin of Campylobacter jejuni |
| US20110294726A1 (en) | 2009-02-11 | 2011-12-01 | Cedars-Sinai Medical Center | Antibiotic therapy to reduce the likelihood of developing post-infectious irritable bowel syndrome |
| US9702884B2 (en) | 2012-09-17 | 2017-07-11 | Cedars-Sinai Medical Center | Methods for detecting the presence of irritable bowel syndrome and system for diagnosing same |
| FR2942541A1 (fr) | 2009-02-25 | 2010-08-27 | Assist Publ Hopitaux De Paris | Procede de diagnostic d'une vascularite |
| RU2397178C1 (ru) * | 2009-02-27 | 2010-08-20 | Федеральное государственное учреждение науки "Центральный научно-исследовательский институт эпидемиологии" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Диагностическая тест-система в формате иммуночипа и способ серологической дифференциальной диагностики сифилиса |
| IT1400989B1 (it) | 2010-07-13 | 2013-07-05 | Segix Italia S R L Ora Istituto Biochimico Naz Savio S R L | Forme di somministrazione orale a rilascio controllato di rifampicina per il trattamento di infezioni batteriche dell' apparato intestinale. |
| GB201017520D0 (en) | 2010-10-15 | 2010-12-01 | Sense Proteomic Ltd | Biomarkers |
| JP5477671B2 (ja) | 2012-02-28 | 2014-04-23 | 三菱マテリアル株式会社 | サーミスタ用金属窒化物材料及びその製造方法並びにフィルム型サーミスタセンサ |
| NZ717633A (en) | 2013-10-09 | 2021-07-30 | Cedars Sinai Medical Center | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
| CN107003308B (zh) | 2014-10-09 | 2020-02-11 | 西达-赛奈医疗中心 | 用于区分肠易激综合征与炎性肠病和乳糜泻的方法和系统 |
| EP3573650A4 (en) | 2017-01-30 | 2020-12-09 | Cedars-Sinai Medical Center | DIAGNOSIS OF SCLERODERMIA |
-
2015
- 2015-10-08 CN CN201580067387.5A patent/CN107003308B/zh active Active
- 2015-10-08 AU AU2015330872A patent/AU2015330872B2/en active Active
- 2015-10-08 RU RU2017115663A patent/RU2706361C2/ru active IP Right Revival
- 2015-10-08 WO PCT/US2015/054655 patent/WO2016057772A1/en not_active Ceased
- 2015-10-08 US US14/878,416 patent/US10132814B2/en active Active
- 2015-10-08 CA CA2962493A patent/CA2962493C/en active Active
- 2015-10-08 PT PT158497016T patent/PT3204771T/pt unknown
- 2015-10-08 KR KR1020177011301A patent/KR102426541B1/ko active Active
- 2015-10-08 MX MX2017004516A patent/MX384921B/es unknown
- 2015-10-08 ES ES15849701T patent/ES3028294T3/es active Active
- 2015-10-08 EP EP15849701.6A patent/EP3204771B1/en active Active
- 2015-10-08 SG SG11201702395WA patent/SG11201702395WA/en unknown
- 2015-10-08 PL PL15849701.6T patent/PL3204771T3/pl unknown
- 2015-10-08 NZ NZ730490A patent/NZ730490A/en unknown
- 2015-10-08 JP JP2017518834A patent/JP6784669B2/ja active Active
-
2017
- 2017-04-05 IL IL251606A patent/IL251606B/en active IP Right Grant
-
2018
- 2018-10-05 US US16/152,806 patent/US10690679B2/en active Active
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