JP2013505928A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013505928A5 JP2013505928A5 JP2012530383A JP2012530383A JP2013505928A5 JP 2013505928 A5 JP2013505928 A5 JP 2013505928A5 JP 2012530383 A JP2012530383 A JP 2012530383A JP 2012530383 A JP2012530383 A JP 2012530383A JP 2013505928 A5 JP2013505928 A5 JP 2013505928A5
- Authority
- JP
- Japan
- Prior art keywords
- hpmc
- gellan gum
- capsule
- acid
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PUSNGFYSTWMJSK-GSZQVNRLSA-N (2R,3R,4S,5R,6R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane;1-[[(2R,3R,4S,5R,6S)-3,4,5-tris(2-hydroxypropoxy)-6-[(2R,3R,4S,5R,6R)-4,5,6-tris(2-hydroxypropoxy)-2-(2-hydroxypropoxymethyl)oxan- Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](OC)O[C@@H]1COC.CC(O)CO[C@@H]1[C@@H](OCC(C)O)[C@H](OCC(C)O)[C@@H](COCC(O)C)O[C@H]1O[C@H]1[C@H](OCC(C)O)[C@@H](OCC(C)O)[C@H](OCC(C)O)O[C@@H]1COCC(C)O PUSNGFYSTWMJSK-GSZQVNRLSA-N 0.000 claims 7
- 229920002148 Gellan gum Polymers 0.000 claims 7
- 235000010492 gellan gum Nutrition 0.000 claims 7
- 239000000216 gellan gum Substances 0.000 claims 7
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 7
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 7
- 239000002253 acid Substances 0.000 claims 6
- 239000002775 capsule Substances 0.000 claims 6
- 239000007902 hard capsule Substances 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 2
- 239000000796 flavoring agent Substances 0.000 claims 2
- 235000013355 food flavoring agent Nutrition 0.000 claims 2
- 230000002496 gastric Effects 0.000 claims 2
- 230000003000 nontoxic Effects 0.000 claims 2
- 231100000252 nontoxic Toxicity 0.000 claims 2
- 239000000049 pigment Substances 0.000 claims 2
- 239000004014 plasticizer Substances 0.000 claims 2
- 231100000486 side effect Toxicity 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 210000004051 Gastric Juice Anatomy 0.000 claims 1
- 239000003125 aqueous solvent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Claims (7)
- 水分、ジェランガム、及びＨＰＭＣ、並びに場合により、少なくとも１つの不活性で非毒性の医薬品グレード又は食品グレードの顔料、可塑剤、界面活性剤、又は矯味矯臭剤からなるカプセルシェルを含む、耐酸性医薬用硬カプセルであり；ここでＨＰＭＣに対するジェランガムの質量比は、下端及び上端を含めて４／１００〜１５／１００の間であり、そしてさらに前記カプセルが、ＵＳＰ−３０人工胃液中ｐＨ１.２で少なくとも１時間漏出に耐性を示す、上記耐酸性医薬用硬カプセル。
- 前記シェルが、１つ若しくはそれ以上の酸不安定性物質、並びに／又はヒト及び／若しくは動物において胃の副作用と関連する１つ若しくはそれ以上の物質で充填される、請求項１に記載の硬カプセル。
- 耐酸性医薬用硬カプセルシェル及びカプセルの製造のための、水性溶媒、ジェランガム及びＨＰＭＣ、並びに場合により、少なくとも１つの不活性で非毒性の医薬品グレード又は食品グレードの顔料、可塑剤、界面活性剤、又は矯味矯臭剤からなり；ここでＨＰＭＣに対するジェランガムの質量比は、下端及び上端を含めて４／１００〜１５／１００の間である、水性組成物の使用。
- 前記カプセルシェル及びカプセルが、１つ若しくはそれ以上の酸不安定性物質、並びに／又はヒト及び／若しくは動物において胃の副作用と関連する１つ若しくはそれ以上の物質で充填される、請求項３に記載の使用。
- 耐酸性を医薬用硬カプセルシェル及びカプセルに付与するための、４／１００〜１５／１００との間の質量比の、ジェランガムとＨＰＭＣとの混合物の使用。
- ジェランガムが、ＨＰＭＣの１００質量部当たり、下端及び上端を含めて４．５〜６重量部の比率で使用される、請求項３に記載の使用。
- 水性組成物中で、ジェランガムとＨＰＭＣの合わせた量が、水性組成物の総質量に対して１５質量％〜４０質量％の間である、請求項３に記載の使用。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24539209P | 2009-09-24 | 2009-09-24 | |
| US61/245,392 | 2009-09-24 | ||
| PCT/IB2010/054131 WO2011036601A1 (en) | 2009-09-24 | 2010-09-14 | Acid resistant capsules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013505928A JP2013505928A (ja) | 2013-02-21 |
| JP2013505928A5 true JP2013505928A5 (ja) | 2013-10-31 |
| JP5777625B2 JP5777625B2 (ja) | 2015-09-09 |
Family
ID=43027570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012530383A Active JP5777625B2 (ja) | 2009-09-24 | 2010-09-14 | 耐酸性カプセル |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US8852631B2 (ja) |
| EP (1) | EP2480218B1 (ja) |
| JP (1) | JP5777625B2 (ja) |
| KR (1) | KR101762460B1 (ja) |
| CN (1) | CN102665697B (ja) |
| AU (1) | AU2010299527A1 (ja) |
| BR (1) | BR112012006651B1 (ja) |
| CA (1) | CA2775227C (ja) |
| CO (1) | CO6531471A2 (ja) |
| DK (1) | DK2480218T3 (ja) |
| ES (1) | ES2804779T3 (ja) |
| MX (1) | MX2012003540A (ja) |
| PL (1) | PL2480218T3 (ja) |
| RU (1) | RU2012116362A (ja) |
| TW (1) | TW201127370A (ja) |
| WO (1) | WO2011036601A1 (ja) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2012116362A (ru) | 2009-09-24 | 2013-10-27 | Кэпсьюджел Белджиум Нв | Кислотоустойчивые капсулы |
| US20140360404A1 (en) | 2011-11-09 | 2014-12-11 | Capsugel Belgium Nv | Acid resistant banding solution for acid resistant two piece hard capsules |
| ES2728850T3 (es) | 2012-05-02 | 2019-10-29 | Capsugel Belgium Nv | Dispersiones acuosas de acetato acetato succinato de hidroxipropilmetilcelulosa (HPMCAS) |
| WO2013175303A1 (en) * | 2012-05-21 | 2013-11-28 | Capsugel Belgium Nv | Acid resistant banding solution for two piece hard capsules |
| WO2013174884A1 (en) | 2012-05-23 | 2013-11-28 | Capsugel France SAS | Capsules having an incorporated taste modifying component |
| JP2014172850A (ja) | 2013-03-07 | 2014-09-22 | Capsugel Belgium Nv | ハードカプセル製剤 |
| JP6133702B2 (ja) * | 2013-06-18 | 2017-05-24 | 紀州技研工業株式会社 | インクジェットインキ、その製造方法及びその使用方法 |
| EP3065720A1 (en) | 2013-11-04 | 2016-09-14 | Capsugel Belgium NV | Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole |
| JP6060102B2 (ja) * | 2014-03-13 | 2017-01-11 | 紀州技研工業株式会社 | インクジェットインク及びその作製方法並びにインクジェットインクを用いた印字方法 |
| CN103893772B (zh) | 2014-04-21 | 2015-08-26 | 湖南尔康制药股份有限公司 | 一种羟丙基淀粉空心胶囊及其制备工艺 |
| CN103937038B (zh) * | 2014-04-28 | 2016-08-17 | 中国科学院化学研究所 | 用于制备空心胶囊的组合物及其淀粉基质空心胶囊 |
| US20170216146A1 (en) * | 2014-07-31 | 2017-08-03 | Capsugel Belgium Nv | Capsule formulation |
| JP6297441B2 (ja) * | 2014-07-31 | 2018-03-20 | 森永乳業株式会社 | ビフィドバクテリウム属細菌含有カプセルおよびその製造方法 |
| EP3028694B1 (en) | 2014-12-02 | 2017-07-12 | Capsugel Belgium NV | Dosage form articles for delayed release |
| WO2016105498A1 (en) | 2014-12-23 | 2016-06-30 | Synthetic Biologics, Inc. | Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics |
| CA2972979C (en) * | 2015-01-13 | 2020-11-03 | New Chapter, Inc. | Vegetarian capsules containing supercritical herbal extracts |
| EP3566699A1 (en) | 2015-11-10 | 2019-11-13 | Capsugel Belgium NV | Acid resistant banding or sealing solution for acid resistant two piece hard capsules |
| US20170157058A1 (en) * | 2015-12-08 | 2017-06-08 | Dah Feng Capsule Industry Co., Ltd. | Acid resistant capsule shell composition, acid resistant capsule shell and its preparing process |
| EP3246000A1 (en) | 2016-05-18 | 2017-11-22 | Capsugel Belgium NV | Separable capsule for sprinkling applications |
| EP3272340A1 (en) | 2016-07-22 | 2018-01-24 | Capsugel Belgium NV | Acid resistant capsules |
| CA3151507C (en) | 2016-08-24 | 2024-05-28 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating functional decline |
| JP2018199631A (ja) * | 2017-05-26 | 2018-12-20 | 株式会社ファンケル | ビフィズス菌含有カプセル製剤 |
| BR112020000011A2 (pt) | 2017-07-11 | 2020-07-21 | Qualicaps Co., Ltd. | cápsula dura entérica |
| CO2017007322A1 (es) * | 2017-07-24 | 2019-01-31 | Novamed S A | Cápsulas duras resistentes al ácido con bajo contenido de coadyuvantes de gelificacion |
| CA3072032A1 (en) | 2017-08-07 | 2019-02-14 | Finch Therapeutics, Inc. | Compositions and methods for maintaining and restoring a healthy gut barrier |
| US11083738B2 (en) | 2017-09-28 | 2021-08-10 | Natals, Inc. | Dietary nutrient compositions |
| WO2019139891A1 (en) | 2018-01-09 | 2019-07-18 | Synthetic Biologics, Inc. | Alkaline phosphatase agents for treatment of neurodevelopmental disorders |
| KR20200125637A (ko) | 2018-02-23 | 2020-11-04 | 크레스토보 홀딩스 엘엘씨 | 마이크로바이옴 관련 면역요법 |
| EP3773686B1 (en) | 2018-03-20 | 2023-06-07 | Theriva Biologics, Inc. | Alkaline phosphatase agents for treatment of radiation disorders |
| EP3768773A4 (en) * | 2018-03-21 | 2022-11-30 | Selby, Ryan Daniel | VAPORIZER CAPSULES AND METHODS OF MAKING |
| EP3549578A1 (en) * | 2018-04-06 | 2019-10-09 | Bio Minerals N.V. | Silicic acid formulation and use thereof |
| CN112566668A (zh) | 2018-06-22 | 2021-03-26 | 快力胶囊股份有限公司 | 肠溶性硬胶囊 |
| EP3632449A1 (en) | 2018-10-05 | 2020-04-08 | Bio Minerals N.V. | Silicic acids for use in the treatment of periodontitis |
| KR102182326B1 (ko) * | 2019-02-19 | 2020-11-24 | 주식회사 서흥 | 내산성 셀룰로오스 캡슐의 제조방법 |
| WO2020182611A1 (en) * | 2019-03-14 | 2020-09-17 | Evonik Operations Gmbh | Capsule shell comprising a core-shell polymer and a cellulose |
| WO2021011754A1 (en) | 2019-07-18 | 2021-01-21 | Synthetic Biologics, Inc. | Intestinal alkaline phosphatase-based treatments of metabolic disorders |
| CN114502182A (zh) | 2019-07-19 | 2022-05-13 | 芬奇治疗控股有限责任公司 | 用于治疗胃肠道病症的方法及产品 |
| US20220331378A1 (en) | 2019-09-13 | 2022-10-20 | Finch Therapeutics Holdings Llc | Compositions and methods for treating autism spectrum disorder |
| MX2022004515A (es) * | 2019-10-16 | 2022-07-12 | Capsugel Belgium Nv | Metodo y composicion para aumentar la sintesis de proteinas musculares. |
| WO2021076920A1 (en) * | 2019-10-16 | 2021-04-22 | Capsugel Belgium Nv | Method and composition for increasing muscle protein synthesis |
| EP4045630A1 (en) | 2019-10-18 | 2022-08-24 | Finch Therapeutics Holdings LLC | Compositions and methods for delivering a bacterial metabolite to a subject |
| WO2021097288A1 (en) | 2019-11-15 | 2021-05-20 | Finch Therapeutics Holdings Llc | Compositions and methods for treating neurodegenerative diseases |
| WO2021142353A1 (en) | 2020-01-10 | 2021-07-15 | Finch Therapeutics Holdings Llc | Compositions and methods for treating hepatitis b (hbv) and hepatitis d (hdv) |
| WO2021142358A1 (en) | 2020-01-10 | 2021-07-15 | Finch Therapeutics Holdings Llc | Compositions and methods for treating hepatic encephalopathy (he) |
| WO2021142347A1 (en) | 2020-01-10 | 2021-07-15 | Finch Therapeutics Holdings Llc | Compositions and methods for non-alcoholic steatohepatitis (nash) |
| WO2021202806A1 (en) | 2020-03-31 | 2021-10-07 | Finch Therapeutics Holdings Llc | Compositions comprising non-viable fecal microbiota and methods of use thereof |
| KR20230017192A (ko) * | 2020-05-31 | 2023-02-03 | 에어젠 파마 엘티디. | 경질 캡슐 투여 형태 및 이의 용도 |
| WO2022055993A1 (en) * | 2020-09-08 | 2022-03-17 | The Johns Hopkins University | Method of treatment of irritable bowel syndrome |
| US20240263251A1 (en) | 2021-02-19 | 2024-08-08 | Finch Therapeutics Holdings Llc | Compositions and methods for providing secondary bile acids to a subject |
| JPWO2022244713A1 (ja) * | 2021-05-18 | 2022-11-24 | ||
| JPWO2023100643A1 (ja) | 2021-11-30 | 2023-06-08 | ||
| CN118340904A (zh) * | 2024-04-19 | 2024-07-16 | 山东赫尔希胶囊有限公司 | 一种羟丙甲纤维素成膜组合物及其应用 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1144225A (en) | 1965-09-07 | 1969-03-05 | Dow Chemical Co | Preparation of medicinal capsule shells from hydroxyalkyl-alkyl cellulose ethers |
| US4756902A (en) | 1986-06-02 | 1988-07-12 | Warner-Lambert Company | Capsule sealing process and product |
| US5006346A (en) | 1988-04-28 | 1991-04-09 | Alza Corporation | Delivery system |
| US5264223A (en) | 1990-03-29 | 1993-11-23 | Japan Elanco Company, Ltd. | Hard capsule for pharmaceutical drugs and method for producing the same |
| JP3116602B2 (ja) | 1992-10-06 | 2000-12-11 | シオノギクオリカプス株式会社 | 硬質カプセル |
| US5431917A (en) | 1992-10-08 | 1995-07-11 | Japan Elanco Company, Ltd. | Hard capsule for pharmaceutical drugs and method for producing the same |
| JPH07196478A (ja) | 1993-12-30 | 1995-08-01 | Hajime Sugii | 安全性の高い食品及び医薬品用ソフトカプセル |
| US5756123A (en) | 1994-12-01 | 1998-05-26 | Japan Elanco Co., Ltd. | Capsule shell |
| FR2757173A1 (fr) | 1996-12-17 | 1998-06-19 | Warner Lambert Co | Compositions polymeres d'origine non-animale pour la formation de films |
| JP4249816B2 (ja) * | 1997-02-24 | 2009-04-08 | 富士カプセル株式会社 | ソフトカプセル |
| CA2307887A1 (en) | 1997-10-31 | 1999-05-14 | Monsanto Company | Gellan gum tablet coating |
| JP3449253B2 (ja) | 1998-10-29 | 2003-09-22 | シオノギクオリカプス株式会社 | 硬質カプセルの製造方法 |
| DE19926714A1 (de) | 1999-01-25 | 2000-08-10 | Su Heung Capsule Co | Pflanzliche Steckkapseln und Verfahren für deren Herstellung |
| JP3716901B2 (ja) | 1999-04-14 | 2005-11-16 | シオノギクオリカプス株式会社 | セルロースエーテルフィルム |
| US6294008B1 (en) | 1999-04-21 | 2001-09-25 | The Dow Chemical Company | Haze-free cellulose ether capsules and process for making |
| DE60020716T2 (de) | 1999-07-22 | 2005-12-15 | Warner-Lambert Co. Llc | Filmbildende zusammensetzungen aus pullulan |
| KR100379674B1 (ko) | 2000-03-06 | 2003-04-10 | 주식회사 서흥캅셀 | 펙틴과 글리세린의 배합용액을 이용한 셀룰로오스 캅셀 및그의 제조방법 |
| GB2366780A (en) | 2000-07-07 | 2002-03-20 | Bioprogress Tech Int Inc | Foam capsules |
| EP1184033A1 (en) | 2000-09-01 | 2002-03-06 | Warner-Lambert Company | Pectin film compositions |
| JP2002145783A (ja) | 2000-11-06 | 2002-05-22 | Kohjin Co Ltd | Ｓ−アデノシルメチオニンまたはその塩類を含有するカプセル製剤 |
| US20030072731A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing starch or dextrin |
| GB0221986D0 (en) | 2002-09-21 | 2002-10-30 | Bioprogress Technology Ltd | Films with improved barrier properties |
| CN1694687A (zh) * | 2002-10-22 | 2005-11-09 | 东门投资有限公司 | 胶囊和含阿拉伯树胶的成膜组合物 |
| TW200520790A (en) | 2003-12-22 | 2005-07-01 | Dah Feng Capsule Industry Co Ltd | The compositions of a vegetarian capsule shell |
| US20070298095A1 (en) | 2004-05-24 | 2007-12-27 | Shionogi Qualicaps Co., Ltd. | Surface-Modified and Solubility-Improved Hard Capsule |
| WO2006043284A1 (en) | 2004-10-21 | 2006-04-27 | Sunil Mundra | A process for manufacturing neutraceutical, pharmaceutical cellulose derivatives capsule |
| JPWO2006070578A1 (ja) | 2004-12-28 | 2008-06-12 | クオリカプス株式会社 | 硬カプセルのバンドシール |
| KR100661336B1 (ko) | 2005-02-21 | 2006-12-27 | 주식회사 서흥캅셀 | 기계적 피막강도를 향상시킨 셀룰로오스 경질캅셀 |
| WO2006136196A1 (en) * | 2005-06-21 | 2006-12-28 | V. Mane Fils | Gellan seamless breakable capsule and process for manufacturing thereof |
| US20070043284A1 (en) | 2005-08-16 | 2007-02-22 | Robert Sanfilippo | Medical electrode and method of use |
| EP1762232A1 (en) | 2005-09-09 | 2007-03-14 | Warner-Lambert Company LLC | Liquid filled delivery system, preferably an HPMC capsule filled with glycerol |
| EP1983969A4 (en) | 2006-01-24 | 2012-10-31 | Qualicaps Co Ltd | HUMIDITY LOW HUMIDITY CAPSULE AND METHOD FOR PRODUCING THE SAME |
| WO2007098612A1 (en) | 2006-03-02 | 2007-09-07 | Laboratoires Mauves Inc. | Gastric acid resistant gelatin capsule composition and method for producing same |
| WO2008005742A2 (en) * | 2006-06-30 | 2008-01-10 | Mcneil-Ppc, Inc. | Ibuprofen-containing liquid filled hard capsules |
| KR20120038021A (ko) * | 2006-10-27 | 2012-04-20 | 화이자 프로덕츠 인코포레이티드 | 하이드록시프로필 메틸 셀룰로스 경질 캡슐 및 이의 제조 방법 |
| GB0706178D0 (en) * | 2007-03-29 | 2007-05-09 | Univ Aston | Enteric pharmaceutical capsules |
| EP2179728A4 (en) | 2007-08-10 | 2013-01-23 | Shanghai Huiyuan Vegetal Capsule Co Ltd | NON-GELATINEOUS ENVELOPE MATERIAL FOR HARD CAPSULE AND PREPARATION METHOD |
| EP2223685A4 (en) | 2007-11-13 | 2013-08-21 | Shanghai Huiyuan Vegetal Capsule Co Ltd | HARD-GEL CELLULAR, GASTRORESISTANT AND GELATIN-FREE ENVELOPE AND PROCESS FOR PREPARING THE SAME |
| JP5178236B2 (ja) * | 2008-02-25 | 2013-04-10 | クオリカプス株式会社 | 腸溶性カプセル |
| US8825387B2 (en) | 2008-07-25 | 2014-09-02 | Navteq B.V. | Positioning open area maps |
| JP5253235B2 (ja) * | 2009-03-02 | 2013-07-31 | クオリカプス株式会社 | 腸溶性カプセル |
| RU2012102772A (ru) | 2009-06-29 | 2013-08-10 | МакНЕЙЛ-ППС, ИНК. | Фармацевтическая таблетка, содержащая заполненную жидкостью капсулу |
| JP2013503847A (ja) | 2009-09-04 | 2013-02-04 | キャプシュゲル・ベルジウム・エヌ・ヴィ | 着香カプセル |
| RU2012116362A (ru) | 2009-09-24 | 2013-10-27 | Кэпсьюджел Белджиум Нв | Кислотоустойчивые капсулы |
| EP2750600B1 (en) | 2011-09-14 | 2017-04-12 | Capsugel Belgium NV | Fill formulations and capsules and method of use to avoid migration of fill into or through the shell |
| JP2014172850A (ja) | 2013-03-07 | 2014-09-22 | Capsugel Belgium Nv | ハードカプセル製剤 |
| US20170216146A1 (en) | 2014-07-31 | 2017-08-03 | Capsugel Belgium Nv | Capsule formulation |
| WO2016099921A1 (en) | 2014-12-16 | 2016-06-23 | E. I. Du Pont De Nemours And Company | Films, fluoropolymer coated films and highly cleanable articles |
| TWI587880B (zh) | 2015-03-24 | 2017-06-21 | Can be made into the composition of enteric capsule shell, enteric capsule shell and its process | |
| US9452141B1 (en) | 2015-05-01 | 2016-09-27 | Dah Feng Capsule Industry Co., Ltd. | Acid resistant capsule shell composition, acid resistant capsule shell and its preparing process |
| US20170157058A1 (en) | 2015-12-08 | 2017-06-08 | Dah Feng Capsule Industry Co., Ltd. | Acid resistant capsule shell composition, acid resistant capsule shell and its preparing process |
-
2010
- 2010-09-14 RU RU2012116362/15A patent/RU2012116362A/ru not_active Application Discontinuation
- 2010-09-14 BR BR112012006651-0A patent/BR112012006651B1/pt active IP Right Grant
- 2010-09-14 AU AU2010299527A patent/AU2010299527A1/en not_active Abandoned
- 2010-09-14 EP EP10759732.0A patent/EP2480218B1/en active Active
- 2010-09-14 WO PCT/IB2010/054131 patent/WO2011036601A1/en active Application Filing
- 2010-09-14 KR KR1020127010224A patent/KR101762460B1/ko active IP Right Grant
- 2010-09-14 CA CA2775227A patent/CA2775227C/en active Active
- 2010-09-14 ES ES10759732T patent/ES2804779T3/es active Active
- 2010-09-14 JP JP2012530383A patent/JP5777625B2/ja active Active
- 2010-09-14 MX MX2012003540A patent/MX2012003540A/es active IP Right Grant
- 2010-09-14 DK DK10759732.0T patent/DK2480218T3/da active
- 2010-09-14 CN CN201080042764.7A patent/CN102665697B/zh active Active
- 2010-09-14 US US13/497,974 patent/US8852631B2/en active Active
- 2010-09-14 PL PL10759732T patent/PL2480218T3/pl unknown
- 2010-09-21 TW TW099132015A patent/TW201127370A/zh unknown
-
2012
- 2012-04-25 CO CO12067580A patent/CO6531471A2/es unknown
-
2014
- 2014-08-27 US US14/470,442 patent/US9700517B2/en active Active
-
2017
- 2017-05-04 US US15/587,169 patent/US10231934B2/en active Active
-
2019
- 2019-02-21 US US16/281,817 patent/US10874619B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013505928A5 (ja) | ||
| RU2012116362A (ru) | Кислотоустойчивые капсулы | |
| JP2012031131A5 (ja) | ||
| JP2012255026A5 (ja) | ||
| WO2007075475A3 (en) | Gastric reflux resistant dosage forms | |
| JP2012031147A5 (ja) | ||
| JP2008504257A5 (ja) | ||
| EP2600849A4 (en) | COMPOSITION FORMING A FILM FOR SOFT CAPSULES | |
| CN105142618A (zh) | 提供药理及临床效应的莫沙必利每日单次施用缓释制剂 | |
| JP2011519967A5 (ja) | ||
| CN103520727B (zh) | 一种胶囊壳及其制备方法 | |
| HRP20240115T1 (hr) | Povećavanje bioraspoloživosti lijeka u terapiji naltreksonom | |
| JP2009505991A5 (ja) | ||
| CN105142617B (zh) | 双用途硫酸盐口服药物组合物片剂及其使用方法 | |
| JP2006342148A5 (ja) | ||
| JP2018513204A5 (ja) | ||
| TW202308599A (zh) | 軟膠囊 | |
| Decamp et al. | Probiotics as alternative to antimicrobials: limitations and potential | |
| JP2014525749A5 (ja) | ||
| JP2015533484A5 (ja) | ||
| KR102361246B1 (ko) | 시스테아민 또는 이의 염을 포함하는 서방형 약학적 조성물 | |
| US20070077294A1 (en) | Capsules comprising topiramate | |
| JP2019534046A5 (ja) | ||
| JP2014533689A5 (ja) | ||
| WO2018080795A1 (en) | Hydroxycitric acid compounds and capsule liquid delivery |