JP2013503251A5 - - Google Patents
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- Publication number
- JP2013503251A5 JP2013503251A5 JP2012527045A JP2012527045A JP2013503251A5 JP 2013503251 A5 JP2013503251 A5 JP 2013503251A5 JP 2012527045 A JP2012527045 A JP 2012527045A JP 2012527045 A JP2012527045 A JP 2012527045A JP 2013503251 A5 JP2013503251 A5 JP 2013503251A5
- Authority
- JP
- Japan
- Prior art keywords
- template
- composition
- monomers
- mycotoxins
- crosslinking agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 14
- 231100000678 Mycotoxin Toxicity 0.000 claims 13
- 239000002636 mycotoxin Substances 0.000 claims 13
- 239000000178 monomer Substances 0.000 claims 11
- 229920000642 polymer Polymers 0.000 claims 9
- 239000003431 cross linking reagent Substances 0.000 claims 8
- 239000000463 material Substances 0.000 claims 7
- RYIYEOCVEAPTRJ-ZDUSSCGKSA-N (2s)-2-[(3,5-dichloro-2-hydroxybenzoyl)amino]-3-phenylpropanoic acid Chemical compound C([C@@H](C(=O)O)NC(=O)C=1C(=C(Cl)C=C(Cl)C=1)O)C1=CC=CC=C1 RYIYEOCVEAPTRJ-ZDUSSCGKSA-N 0.000 claims 3
- 239000004971 Cross linker Substances 0.000 claims 3
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 claims 2
- DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical compound FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 claims 2
- GAZMGJRSHRHHAW-UHFFFAOYSA-N 5-chloro-6,7-dimethoxy-1-methylindole-2,3-dione Chemical compound ClC1=C(OC)C(OC)=C2N(C)C(=O)C(=O)C2=C1 GAZMGJRSHRHHAW-UHFFFAOYSA-N 0.000 claims 2
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 2
- STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Substances CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 238000006116 polymerization reaction Methods 0.000 claims 2
- LQCBOYUDOCGUIN-UHFFFAOYSA-N 6,7-dimethoxy-1-methylindole-2,3-dione Chemical compound COC1=CC=C2C(=O)C(=O)N(C)C2=C1OC LQCBOYUDOCGUIN-UHFFFAOYSA-N 0.000 claims 1
- JWSVFVKYHWGSGY-UHFFFAOYSA-N 6,7-dimethoxy-1h-indole-2,3-dione Chemical compound COC1=CC=C2C(=O)C(=O)NC2=C1OC JWSVFVKYHWGSGY-UHFFFAOYSA-N 0.000 claims 1
- VYLQGYLYRQKMFU-UHFFFAOYSA-N Ochratoxin A Natural products CC1Cc2c(Cl)cc(CNC(Cc3ccccc3)C(=O)O)cc2C(=O)O1 VYLQGYLYRQKMFU-UHFFFAOYSA-N 0.000 claims 1
- 229930188346 Sporidesmin Natural products 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 150000007942 carboxylates Chemical class 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 235000012041 food component Nutrition 0.000 claims 1
- 239000005417 food ingredient Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- RWQKHEORZBHNRI-BMIGLBTASA-N ochratoxin A Chemical compound C([C@H](NC(=O)C1=CC(Cl)=C2C[C@H](OC(=O)C2=C1O)C)C(O)=O)C1=CC=CC=C1 RWQKHEORZBHNRI-BMIGLBTASA-N 0.000 claims 1
- DAEYIVCTQUFNTM-UHFFFAOYSA-N ochratoxin B Natural products OC1=C2C(=O)OC(C)CC2=CC=C1C(=O)NC(C(O)=O)CC1=CC=CC=C1 DAEYIVCTQUFNTM-UHFFFAOYSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- QTONANGUNATZOU-ICTVWZTPSA-N sporidesmin A Chemical compound S([C@](N(C1=O)C)(C)C(=O)N23)S[C@@]21[C@H](O)[C@@]1(O)[C@@H]3N(C)C2=C(OC)C(OC)=C(Cl)C=C21 QTONANGUNATZOU-ICTVWZTPSA-N 0.000 claims 1
- QTONANGUNATZOU-UHFFFAOYSA-N sporidesmin-A Natural products N12C(=O)C(N(C3=O)C)(C)SSC23C(O)C2(O)C1N(C)C1=C(OC)C(OC)=C(Cl)C=C12 QTONANGUNATZOU-UHFFFAOYSA-N 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23754909P | 2009-08-27 | 2009-08-27 | |
| US61/237,549 | 2009-08-27 | ||
| PCT/US2010/047032 WO2011031562A1 (en) | 2009-08-27 | 2010-08-27 | Synthetic mycotoxin adsorbents and methods of making and utilizing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013503251A JP2013503251A (ja) | 2013-01-31 |
| JP2013503251A5 true JP2013503251A5 (enExample) | 2013-10-10 |
| JP5650223B2 JP5650223B2 (ja) | 2015-01-07 |
Family
ID=43625814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012527045A Active JP5650223B2 (ja) | 2009-08-27 | 2010-08-27 | 合成マイコトキシン吸着剤ならびにそれを生成および使用する方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US8153737B2 (enExample) |
| EP (1) | EP2470894B1 (enExample) |
| JP (1) | JP5650223B2 (enExample) |
| KR (2) | KR101406960B1 (enExample) |
| CN (3) | CN102549424B (enExample) |
| AU (1) | AU2010292495B2 (enExample) |
| BR (1) | BR112012004316B1 (enExample) |
| CA (1) | CA2770343C (enExample) |
| CL (1) | CL2012000494A1 (enExample) |
| CO (1) | CO6440520A2 (enExample) |
| EA (2) | EA024530B9 (enExample) |
| IN (1) | IN2012DN01219A (enExample) |
| MA (1) | MA33597B1 (enExample) |
| MX (1) | MX2012002494A (enExample) |
| MY (2) | MY171129A (enExample) |
| NZ (2) | NZ598160A (enExample) |
| PE (2) | PE20120862A1 (enExample) |
| UA (1) | UA105228C2 (enExample) |
| WO (1) | WO2011031562A1 (enExample) |
| ZA (1) | ZA201200973B (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008051285A2 (en) | 2006-04-01 | 2008-05-02 | Medical Service Consultation International, Llc | Methods and compositions for detecting fungi and mycotoxins |
| TWI421037B (zh) | 2006-12-07 | 2014-01-01 | British American Tobacco Co | 選作為煙草特異性亞硝胺類之分子拓印的聚合物及使用其之方法 |
| GB201200878D0 (en) * | 2012-01-19 | 2012-02-29 | British American Tobacco Co | Polymer compositions |
| US20100068718A1 (en) | 2008-08-22 | 2010-03-18 | Hooper Dennis G | Methods and Compositions for Identifying Yeast |
| US8962251B2 (en) | 2009-10-08 | 2015-02-24 | Medical Service Consultation International, Llc | Methods and compositions for identifying sulfur and iron modifying bacteria |
| US9260683B2 (en) | 2011-10-13 | 2016-02-16 | The Trustees Of Dartmouth College | Molecularly imprinted polymer for wine, method of preparing, and use of same |
| ES2427689B2 (es) * | 2012-03-30 | 2014-04-07 | Universidad Complutense De Madrid | Materiales para el reconocimiento selectivo de micotoxinas de Alternaria (alternariol y alternariol monometil éter) |
| CN102744048B (zh) * | 2012-07-25 | 2015-07-15 | 长安大学 | 酵母菌微球体磁性复合材料表面印迹吸附剂的制备方法 |
| US10000598B2 (en) * | 2012-10-15 | 2018-06-19 | The Trustees Of Dartmouth College | Methods for preparation of molecularly imprinted polymers for wine extraction |
| US11326197B2 (en) | 2012-10-29 | 2022-05-10 | Freshair Sensor, Llc | Molecularly imprinted polymer-based passive sensor |
| ES2732481T3 (es) | 2013-03-27 | 2019-11-22 | Biotage Ab | Uso de un sorbente para extraer micotoxinas |
| CN103524676B (zh) * | 2013-08-26 | 2014-09-17 | 陕西师范大学 | 2-[(6-氧代-6H-苯并[c]色满-3-基)氧基]丙酸整体柱的制备方法及应用 |
| FR3013057B1 (fr) * | 2013-11-08 | 2017-12-22 | Univ Bourgogne | Utilisation d'un polymere a empreintes moleculaires pour pieger l'iprodione en milieu aqueux |
| CN103604674A (zh) * | 2013-11-21 | 2014-02-26 | 四川理工学院 | 一种大曲中赭曲霉毒素a的提取、纯化方法 |
| WO2015130529A2 (en) | 2014-02-25 | 2015-09-03 | Freshair Sensor Corporation | Molecularly imprinted polymer sensors |
| RU2670917C9 (ru) | 2014-02-26 | 2018-12-12 | Кемин Индастриз, Инк. | Применение бета-цеолита в качестве вещества, связывающего мультитоксины в корме для животных |
| CN104034835B (zh) * | 2014-05-27 | 2016-08-24 | 中华人民共和国苏州出入境检验检疫局 | 发酵酒中多种生物毒素的检测方法 |
| RU2705210C2 (ru) * | 2015-02-04 | 2019-11-06 | Олтек, Инк. | Шаблоны афлатоксина, полимеры с молекулярными отпечатками и способы их получения и применения |
| US20160221983A1 (en) * | 2015-02-04 | 2016-08-04 | Alltech, Inc. | Aflatoxin templates, molecularly imprinted polymers, and methods of making and using the same |
| US20180246097A1 (en) * | 2015-09-17 | 2018-08-30 | Advatect Diagnostics, Llc | Methods and compositions for detecting mycotoxins |
| US10721950B2 (en) * | 2015-09-29 | 2020-07-28 | Archer Daniels Midland Company | Process for removal of mycotoxins from insoluble plant-derived protein |
| AT518590A3 (de) * | 2016-04-29 | 2022-09-15 | Mosbach Klaus | Speicherung von binärkodes in molekular geprägten polymeren |
| CN106362654B (zh) * | 2016-10-08 | 2019-04-02 | 江苏大学 | 一种磁性蛋壳粉稳定的Pickering乳液聚合技术制备印迹微球的方法 |
| JP7276315B2 (ja) * | 2018-03-15 | 2023-05-18 | 東亞合成株式会社 | 重合体微粒子の製造方法 |
| CN109342626A (zh) * | 2018-11-28 | 2019-02-15 | 福州大学 | 特异性识别赭曲霉毒素a的poss有机-无机杂化分子印迹整体柱及其制备方法 |
| CN109627381B (zh) * | 2018-12-20 | 2020-09-25 | 成都医学院 | 一种虚拟模板在制备腾毒素分子印迹聚合物中的应用及腾毒素分子印迹聚合物的制备方法 |
| CN109734929B (zh) * | 2019-01-07 | 2021-07-13 | 安徽中烟工业有限责任公司 | 一种核壳微球结构的麦芽酚磁性分子印迹固相萃取材料的制备方法及其应用 |
| CN109601822B (zh) * | 2019-01-22 | 2022-11-08 | 北京三强核力辐射工程技术有限公司 | 一种生物碱协同辐照降解动物源性食品中抗生素的方法 |
| CN110646557A (zh) * | 2019-10-12 | 2020-01-03 | 北京航空航天大学 | 携带idh基因突变的胶质母细胞瘤患者的尿液代谢标志物及其用途 |
| US20240024496A1 (en) * | 2020-12-22 | 2024-01-25 | Intervet Inc. | Conjugated zearalenone to protect against mycotoxicosis |
| CN114685607B (zh) * | 2020-12-28 | 2025-02-28 | 深圳翰宇药业股份有限公司 | 一种依替巴肽杂质i的制备方法 |
| CA3210130A1 (en) * | 2021-03-04 | 2022-09-09 | Aliasghar GOLBABANEZHADAZIZI | Porous sorptive solid phase microextraction devices and preparation thereof |
| CN113234188B (zh) * | 2021-04-02 | 2022-02-15 | 华南理工大学 | 一种分子印迹光子晶体及其制备方法和应用 |
| AU2022277989B2 (en) | 2021-05-21 | 2024-03-14 | Anpario Plc | Composition for use in the treatment and/or prevention of mycotoxic disease |
| CN113929842B (zh) * | 2021-11-17 | 2024-02-09 | 浙江省农业科学院 | 一种白僵菌素的磁性分子印迹材料及其应用 |
| CN115901413B (zh) * | 2022-12-23 | 2023-07-11 | 吉林省农业科学院 | 一种土壤颗粒有机碳测试前处理装置 |
| CN116284960B (zh) * | 2023-03-08 | 2024-12-24 | 北京市农林科学院 | 一种伏马菌素分子印迹聚合物的制备方法和应用 |
| CN116870884B (zh) * | 2023-07-26 | 2025-06-17 | 宁夏大学 | 一种l-赖氨酸衍生的凝胶因子混合模式色谱固定相及其制备方法和应用 |
| CN120059297A (zh) * | 2025-04-28 | 2025-05-30 | 广西产研院新型功能材料研究所有限公司 | 一种橡胶用交联剂及其制备方法 |
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| JPS5413496B2 (enExample) | 1972-10-17 | 1979-05-31 | ||
| US4015018A (en) | 1975-11-06 | 1977-03-29 | Food Technology Products | Silage process and product |
| US4055667A (en) | 1975-12-03 | 1977-10-25 | Ogilvie Mills Ltd. | Animal feeds |
| FR2380986A1 (fr) | 1977-02-16 | 1978-09-15 | Rhone Poulenc Ind | Nouveau procede de stabilisation du metasilicate de sodium anhydre et produit ainsi obtenu |
| US4251519A (en) | 1979-07-30 | 1981-02-17 | Anheuser-Busch, Incorporated | Process for the prevention and reduction of elevated blood cholesterol and triglycerides levels |
| FR2530647A1 (fr) | 1982-07-20 | 1984-01-27 | Rhone Poulenc Spec Chim | Procede de preparation de flocons de polymeres acryliques hydrosolubles |
| US4765992A (en) | 1984-06-01 | 1988-08-23 | Universite De Bordeaux Ii | Stimulation of alcoholic fermentation by adsorption of toxic substances with cell walls |
| CA1320718C (en) | 1987-06-08 | 1993-07-27 | Richard Frederick Hammen | Chromatographic material |
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| US5165946A (en) | 1990-03-07 | 1992-11-24 | Engelhard Corporation | Animal feed additive and method for inactivating mycotoxins present in animal feeds |
| US5192547A (en) | 1990-10-01 | 1993-03-09 | Engelhard Corporation | Animal feed containing selected montmorillonite clay as additive and method for selecting the clay |
| US5149549A (en) | 1990-11-21 | 1992-09-22 | American Colloid Company | Method and composition for achieving animal weight gain with mycotoxin-contaminated animal food |
| DE4130475A1 (de) | 1991-09-13 | 1993-03-18 | Merck Patent Gmbh | Modifizierte chromatographische traegermaterialien |
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| US5372818A (en) | 1993-02-01 | 1994-12-13 | Clemson University | Method of treating fescue toxicosis with domperidone |
| JPH07274947A (ja) | 1994-04-08 | 1995-10-24 | Ebara Res Co Ltd | 飼料化酵母の製造方法 |
| US5639492A (en) | 1995-01-13 | 1997-06-17 | Amcol International Corporation | Method and composition for achieving animal weight gain with mycotoxin-contaminated animal food |
| US5922373A (en) | 1997-05-05 | 1999-07-13 | The Ohio State University | Process for preparing a soy protein feed with enhanced nutritional value |
| US5935623A (en) | 1998-01-15 | 1999-08-10 | Milwhite, Inc. | Use of thermally treated clays in animal feeds |
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| WO2002059184A2 (en) * | 2001-01-24 | 2002-08-01 | Virginia Commonwealth University | Molecular imprinting of small particles, and production of small particles from solid state reactants |
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| JP2004250329A (ja) * | 2002-12-26 | 2004-09-09 | Dainippon Pharmaceut Co Ltd | イサチン誘導体 |
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| DE102006007796B3 (de) * | 2006-02-20 | 2008-01-10 | Kist-Europe Forschungsgesellschaft Mbh | Verfahren zur selektiven Behandlung von schwer abbaubaren und/oder toxischen Verbindungen in Abwasser oder Wasser |
| RU2356621C2 (ru) * | 2006-06-28 | 2009-05-27 | Оао "Мапо-Фонд" | Способ получения настраиваемых сорбентов на основе полимеров с молекулярными отпечатками |
| JP5007905B2 (ja) * | 2007-08-29 | 2012-08-22 | 公立大学法人大阪府立大学 | 分子鋳型を有するポリマーを備えたセンサー |
| CN101216464B (zh) * | 2007-12-29 | 2010-10-20 | 中国农业大学 | 一种检测孔雀石绿的分子印迹聚合物微球 |
| CN201184874Y (zh) * | 2008-05-07 | 2009-01-21 | 济南大学 | 用于真菌毒素检测的分子印迹膜电极 |
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| CN101507916B (zh) * | 2009-02-16 | 2011-01-19 | 西北工业大学 | 大环内酯类抗生素分子印迹聚合物微球的制备方法 |
-
2010
- 2010-08-27 IN IN1219DEN2012 patent/IN2012DN01219A/en unknown
- 2010-08-27 AU AU2010292495A patent/AU2010292495B2/en active Active
- 2010-08-27 UA UAA201202293A patent/UA105228C2/ru unknown
- 2010-08-27 CN CN201080043818.1A patent/CN102549424B/zh active Active
- 2010-08-27 KR KR1020127003825A patent/KR101406960B1/ko active Active
- 2010-08-27 NZ NZ598160A patent/NZ598160A/en unknown
- 2010-08-27 PE PE2012000245A patent/PE20120862A1/es active IP Right Grant
- 2010-08-27 EA EA201290061A patent/EA024530B9/ru not_active IP Right Cessation
- 2010-08-27 CN CN201510468506.XA patent/CN105218393B/zh active Active
- 2010-08-27 EA EA201490727A patent/EA028279B1/ru not_active IP Right Cessation
- 2010-08-27 BR BR112012004316-1A patent/BR112012004316B1/pt active IP Right Grant
- 2010-08-27 CA CA2770343A patent/CA2770343C/en active Active
- 2010-08-27 CN CN201410359900.5A patent/CN104190378B/zh active Active
- 2010-08-27 NZ NZ620131A patent/NZ620131A/en unknown
- 2010-08-27 PE PE2016001566A patent/PE20161381A1/es unknown
- 2010-08-27 US US12/870,664 patent/US8153737B2/en not_active Ceased
- 2010-08-27 KR KR1020147002467A patent/KR101556591B1/ko active Active
- 2010-08-27 MX MX2012002494A patent/MX2012002494A/es active IP Right Grant
- 2010-08-27 JP JP2012527045A patent/JP5650223B2/ja active Active
- 2010-08-27 EP EP10815898.1A patent/EP2470894B1/en active Active
- 2010-08-27 WO PCT/US2010/047032 patent/WO2011031562A1/en not_active Ceased
- 2010-08-27 MY MYPI2014001694A patent/MY171129A/en unknown
- 2010-08-27 MY MYPI2012000654 patent/MY153040A/en unknown
-
2012
- 2012-02-09 ZA ZA2012/00973A patent/ZA201200973B/en unknown
- 2012-02-27 CL CL2012000494A patent/CL2012000494A1/es unknown
- 2012-03-21 MA MA34708A patent/MA33597B1/fr unknown
- 2012-03-22 CO CO12048893A patent/CO6440520A2/es active IP Right Grant
- 2012-04-09 US US13/442,693 patent/US8426541B2/en active Active
-
2014
- 2014-04-08 US US14/247,942 patent/USRE45274E1/en active Active
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