JP2007532632A5 - - Google Patents
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- Publication number
- JP2007532632A5 JP2007532632A5 JP2007507931A JP2007507931A JP2007532632A5 JP 2007532632 A5 JP2007532632 A5 JP 2007532632A5 JP 2007507931 A JP2007507931 A JP 2007507931A JP 2007507931 A JP2007507931 A JP 2007507931A JP 2007532632 A5 JP2007532632 A5 JP 2007532632A5
- Authority
- JP
- Japan
- Prior art keywords
- fold
- hsp
- induction
- vehicle
- data analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000006698 induction Effects 0.000 description 3
- 108020004999 messenger RNA Proteins 0.000 description 3
- 238000007405 data analysis Methods 0.000 description 2
- 108020004463 18S ribosomal RNA Proteins 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN178KO2004 | 2004-04-12 | ||
| IN178/KOL/2004 | 2004-04-12 | ||
| PCT/IN2005/000112 WO2005097746A2 (en) | 2004-04-12 | 2005-04-11 | 2-propene-1-ones as hsp 70 inducers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007532632A JP2007532632A (ja) | 2007-11-15 |
| JP2007532632A5 true JP2007532632A5 (enExample) | 2010-12-24 |
| JP4790704B2 JP4790704B2 (ja) | 2011-10-12 |
Family
ID=34972223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007507931A Expired - Fee Related JP4790704B2 (ja) | 2004-04-12 | 2005-04-11 | Ｈｓｐ７０誘発因子としての２−プロペン−１−オン |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080207608A1 (enExample) |
| EP (1) | EP1748987A2 (enExample) |
| JP (1) | JP4790704B2 (enExample) |
| KR (1) | KR100825492B1 (enExample) |
| CN (1) | CN1964946A (enExample) |
| AU (1) | AU2005232159B2 (enExample) |
| BR (1) | BRPI0509799A (enExample) |
| CA (1) | CA2562130C (enExample) |
| MX (1) | MXPA06011770A (enExample) |
| RU (1) | RU2341522C2 (enExample) |
| WO (1) | WO2005097746A2 (enExample) |
| ZA (1) | ZA200608077B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7893060B2 (en) * | 2007-06-12 | 2011-02-22 | F. Hoffmann-La Roche Ag | Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase |
| KR100989093B1 (ko) | 2008-01-18 | 2010-10-25 | 한화제약주식회사 | 생강나무 가지의 추출물을 포함하는 심혈관계 질환의 예방 및 치료용 조성물 |
| KR101799429B1 (ko) * | 2010-05-03 | 2017-11-21 | 에스케이바이오팜 주식회사 | 신경 세포 사멸 또는 신경 퇴화를 억제하기 위한 약학적 조성물 |
| CN103929959A (zh) | 2011-08-12 | 2014-07-16 | 萨克生物研究学院 | 神经保护性多酚类似物 |
| WO2013025484A1 (en) * | 2011-08-12 | 2013-02-21 | Lapchak Paul A | Polyphenol analogs to treat ischemia |
| CN104520274B (zh) * | 2012-03-29 | 2016-08-24 | 先进癌症治疗有限责任公司 | Pfkfb3抑制剂和用作抗癌治疗剂的方法 |
| WO2014123203A1 (ja) * | 2013-02-06 | 2014-08-14 | 京都薬品工業株式会社 | 糖尿病治療薬 |
| MY191366A (en) | 2013-03-13 | 2022-06-20 | Forma Therapeutics Inc | Novel compounds and compositions for inhibition of fasn |
| WO2015187934A1 (en) * | 2014-06-06 | 2015-12-10 | Cureveda, Llc | Functionalized hetroaryl enones exhibiting nrf2 activation and their method of use |
| WO2016031775A1 (ja) * | 2014-08-25 | 2016-03-03 | 国立大学法人神戸大学 | 植物の耐性向上剤 |
| CN105237487B (zh) * | 2015-10-19 | 2017-10-10 | 安徽中医药大学 | 含川芎嗪基查尔酮芳氧烷酸类化合物、制备方法及其应用 |
| WO2017083979A1 (en) * | 2015-11-20 | 2017-05-26 | Lee Hoyun | Quinolone chalcone compounds and uses thereof |
| CN105503745B (zh) * | 2016-01-07 | 2018-10-19 | 首都师范大学 | 含4-氧代喹唑啉-2-基的查耳酮类似物及其制备方法和用途 |
| CN108558763B (zh) * | 2018-05-16 | 2021-08-24 | 辽宁大学 | 含吲唑的查尔酮类衍生物及其应用 |
| TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
| US10793554B2 (en) | 2018-10-29 | 2020-10-06 | Forma Therapeutics, Inc. | Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone |
| CN111171018B (zh) * | 2018-11-13 | 2022-08-16 | 沈阳化工研究院有限公司 | 一种查尔酮类化合物及其应用 |
| CN109620827B (zh) * | 2018-12-14 | 2021-01-19 | 中国医学科学院医药生物技术研究所 | 杂环丙烯酮类化合物作为抗菌剂的用途 |
| CA3148310A1 (en) * | 2019-09-13 | 2021-03-18 | Jun Qi | Kdm inhibitors and uses thereof |
| CN114105927B (zh) * | 2020-08-31 | 2023-10-24 | 湖南超亟检测技术有限责任公司 | 一种苯并吡喃腈类荧光分子探针的构建及其体外诊断应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5348945A (en) * | 1990-04-06 | 1994-09-20 | Wake Forest University | Method of treatment with hsp70 |
| US5739170A (en) * | 1992-09-11 | 1998-04-14 | The Regents Of The University Of California | Inhibitors of metazoan parasite proteases |
| HU222994B1 (hu) * | 1995-11-02 | 2004-01-28 | BIOREX Kutató és Fejlesztő Rt. | Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására |
| US6096711A (en) * | 1998-02-25 | 2000-08-01 | Sherman; Michael | Hsp72 induction and applications |
| WO2000018390A1 (fr) * | 1998-09-28 | 2000-04-06 | Hsp Research Institute, Inc. | Inducteurs d'expression de proteine de choc thermique |
| US6174875B1 (en) * | 1999-04-01 | 2001-01-16 | University Of Pittsburgh | Benzoquinoid ansamycins for the treatment of cardiac arrest and stroke |
| AU2003229537A1 (en) * | 2002-05-17 | 2003-12-02 | Lica Pharmaceuticals A/S | Amino-functional chalcones |
| EP1684762A4 (en) * | 2003-11-13 | 2009-06-17 | Ambit Biosciences Corp | UREA DERIVATIVES AS MODULATORS OF KINASE |
-
2005
- 2005-04-11 EP EP05752199A patent/EP1748987A2/en not_active Withdrawn
- 2005-04-11 WO PCT/IN2005/000112 patent/WO2005097746A2/en not_active Ceased
- 2005-04-11 KR KR1020067023669A patent/KR100825492B1/ko not_active Expired - Fee Related
- 2005-04-11 US US11/578,354 patent/US20080207608A1/en not_active Abandoned
- 2005-04-11 AU AU2005232159A patent/AU2005232159B2/en not_active Ceased
- 2005-04-11 CN CNA2005800190202A patent/CN1964946A/zh active Pending
- 2005-04-11 RU RU2006139940/04A patent/RU2341522C2/ru not_active IP Right Cessation
- 2005-04-11 MX MXPA06011770A patent/MXPA06011770A/es active IP Right Grant
- 2005-04-11 JP JP2007507931A patent/JP4790704B2/ja not_active Expired - Fee Related
- 2005-04-11 BR BRPI0509799-1A patent/BRPI0509799A/pt not_active IP Right Cessation
- 2005-04-11 CA CA2562130A patent/CA2562130C/en not_active Expired - Fee Related
-
2006
- 2006-09-28 ZA ZA200608077A patent/ZA200608077B/xx unknown
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