JP2013501733A5 - - Google Patents
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- Publication number
- JP2013501733A5 JP2013501733A5 JP2012524066A JP2012524066A JP2013501733A5 JP 2013501733 A5 JP2013501733 A5 JP 2013501733A5 JP 2012524066 A JP2012524066 A JP 2012524066A JP 2012524066 A JP2012524066 A JP 2012524066A JP 2013501733 A5 JP2013501733 A5 JP 2013501733A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heteroaryl
- compound
- formula
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- OEIAWLSFHGJRST-UHFFFAOYSA-N CC1=CCN1C Chemical compound CC1=CCN1C OEIAWLSFHGJRST-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23259709P | 2009-08-10 | 2009-08-10 | |
| US61/232,597 | 2009-08-10 | ||
| PCT/CA2010/001229 WO2011017800A1 (en) | 2009-08-10 | 2010-08-06 | Methods, compounds, and compositions for delivering 1,3-propan ed isulfonic acid |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015179480A Division JP2016034960A (ja) | 2009-08-10 | 2015-09-11 | １，３−プロパンジスルホン酸を送達するための方法、化合物、および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013501733A JP2013501733A (ja) | 2013-01-17 |
| JP2013501733A5 true JP2013501733A5 (enExample) | 2013-08-29 |
Family
ID=43585812
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012524066A Ceased JP2013501733A (ja) | 2009-08-10 | 2010-08-06 | １，３−プロパンジスルホン酸を送達するための方法、化合物、および組成物 |
| JP2015179480A Pending JP2016034960A (ja) | 2009-08-10 | 2015-09-11 | １，３−プロパンジスルホン酸を送達するための方法、化合物、および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015179480A Pending JP2016034960A (ja) | 2009-08-10 | 2015-09-11 | １，３−プロパンジスルホン酸を送達するための方法、化合物、および組成物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9051248B2 (enExample) |
| EP (1) | EP2464626A4 (enExample) |
| JP (2) | JP2013501733A (enExample) |
| KR (1) | KR20120087878A (enExample) |
| CN (1) | CN102471248B (enExample) |
| AU (1) | AU2010282170B2 (enExample) |
| BR (1) | BR112012002780A2 (enExample) |
| CA (1) | CA2768877A1 (enExample) |
| EA (1) | EA201290007A1 (enExample) |
| IL (1) | IL217572A (enExample) |
| MX (1) | MX2012001671A (enExample) |
| NZ (1) | NZ598085A (enExample) |
| SG (2) | SG10201600910YA (enExample) |
| WO (1) | WO2011017800A1 (enExample) |
| ZA (1) | ZA201201352B (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102471248B (zh) * | 2009-08-10 | 2015-01-07 | Bhi有限合伙公司 | 用于递送1,3-丙二磺酸的方法、化合物和组合物 |
| WO2011107867A2 (en) * | 2010-03-05 | 2011-09-09 | Mahesh Kandula | Compound and composition and their use in the treatment of diseases related to copper retention |
| US9303038B2 (en) | 2011-09-06 | 2016-04-05 | Cellix Bio Private Limited | Compositions and methods for the treatment of epilepsy and neurological diseases |
| US9738631B2 (en) | 2012-05-07 | 2017-08-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological disorders |
| WO2013167990A1 (en) | 2012-05-07 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of depression |
| JP2015522531A (ja) | 2012-05-07 | 2015-08-06 | セリックスビオ プライヴェート リミテッド | 神経筋疾患及び神経変性疾患の治療のための組成物及び方法 |
| US9309233B2 (en) | 2012-05-08 | 2016-04-12 | Cellix Bio Private Limited | Compositions and methods for the treatment of blood clotting disorders |
| US9266823B2 (en) | 2012-05-08 | 2016-02-23 | Cellix Bio Private Limited | Compositions and methods for the treatment of parkinson's disease |
| US9403826B2 (en) | 2012-05-08 | 2016-08-02 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory disorders |
| US9522884B2 (en) | 2012-05-08 | 2016-12-20 | Cellix Bio Private Limited | Compositions and methods for the treatment of metabolic disorders |
| US9434704B2 (en) | 2012-05-08 | 2016-09-06 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological degenerative disorders |
| US9499526B2 (en) | 2012-05-10 | 2016-11-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurologic diseases |
| WO2013168000A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of severe pain |
| WO2013168011A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of chronic pain |
| WO2013168002A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of neurological conditions |
| US9315461B2 (en) | 2012-05-10 | 2016-04-19 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurologic diseases |
| US9321775B2 (en) | 2012-05-10 | 2016-04-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of moderate to severe pain |
| WO2013167997A2 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of metabolic syndrome |
| US9339484B2 (en) | 2012-05-10 | 2016-05-17 | Cellix Bio Private Limited | Compositions and methods for the treatment of restless leg syndrome and fibromyalgia |
| WO2013168004A2 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of fibromyalgia pain |
| US9499527B2 (en) | 2012-05-10 | 2016-11-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of familial amyloid polyneuropathy |
| SG11201407318UA (en) | 2012-05-10 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of metabolic syndrome |
| WO2013168015A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of asthma and allergy |
| US9242939B2 (en) | 2012-05-10 | 2016-01-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of respiratory disorders |
| US9498461B2 (en) | 2012-05-23 | 2016-11-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory bowel disease |
| WO2013175347A2 (en) | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of respiratory disorders |
| WO2013175344A2 (en) | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of periodontitis and rheumatoid arthritis |
| AU2013264820A1 (en) | 2012-05-23 | 2014-11-27 | Cellixbio Private Limited | Compositions and methods for treatment of mucositis |
| AU2013264896A1 (en) | 2012-05-23 | 2014-11-27 | Cellixbio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
| WO2013175376A2 (en) | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of local pain |
| US9108942B1 (en) | 2014-11-05 | 2015-08-18 | Mahesh Kandula | Compositions and methods for the treatment of moderate to severe pain |
| WO2014020480A2 (en) | 2012-08-03 | 2014-02-06 | Mahesh Kandula | Compositions and methods for the treatment migraine and neurologic diseases |
| US9624168B2 (en) | 2012-09-06 | 2017-04-18 | Cellix Bio Private Limited | Compositions and methods for the treatment inflammation and lipid disorders |
| CA2873029A1 (en) | 2012-09-08 | 2014-03-13 | Cellixbio Private Limited | Compositions and methods for the treatment of inflammation and lipid disorders |
| CN103012463B (zh) * | 2013-01-17 | 2016-02-10 | 南京理工大学 | (s)-3-甲基-2-(叔丁基二甲基硅氧基)-1-溴丁烷的合成方法 |
| US9333187B1 (en) | 2013-05-15 | 2016-05-10 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory bowel disease |
| SG11201509782TA (en) | 2013-06-04 | 2015-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of diabetes and pre-diabetes |
| US9096537B1 (en) | 2014-12-31 | 2015-08-04 | Mahesh Kandula | Compositions and methods for the treatment of mucositis |
| CN103755679A (zh) * | 2014-02-14 | 2014-04-30 | 宁德新能源科技有限公司 | 一种亚烷基二磺酸酐的制备方法 |
| ES2721003T3 (es) | 2014-04-30 | 2019-07-26 | Icahn School Med Mount Sinai | Utilización de ácido 1, 3 - propano disulfónico o sales farmacéuticamente aceptables del mismo para el tratamiento de la sarcoidosis |
| EP3240779B1 (en) | 2014-09-26 | 2020-10-28 | Cellixbio Private Limited | Compositions and methods for the treatment of epilepsy and neurological disorders |
| ES2799309T3 (es) | 2014-09-29 | 2020-12-16 | Cellix Bio Private Ltd | Compuestos y composiciones para el tratamiento de esclerosis múltiple |
| CA2965449C (en) | 2014-10-27 | 2020-11-10 | Cellix Bio Private Limited | Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis |
| US9290486B1 (en) | 2014-11-05 | 2016-03-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of epilepsy |
| US9173877B1 (en) | 2014-11-05 | 2015-11-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of local pain |
| US9321716B1 (en) | 2014-11-05 | 2016-04-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of metabolic syndrome |
| US9284287B1 (en) | 2014-11-05 | 2016-03-15 | Cellix Bio Private Limited | Compositions and methods for the suppression of carbonic anhydrase activity |
| US9150557B1 (en) | 2014-11-05 | 2015-10-06 | Cellix Bio Private Limited | Compositions and methods for the treatment of hyperglycemia |
| US9175008B1 (en) | 2014-11-05 | 2015-11-03 | Cellix Bio Private Limited | Prodrugs of anti-platelet agents |
| US10208014B2 (en) | 2014-11-05 | 2019-02-19 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological disorders |
| CN107207411A (zh) | 2014-12-01 | 2017-09-26 | 塞尔利克斯生物私人有限公司 | 用于治疗多发性硬化的组合物和方法 |
| US9206111B1 (en) | 2014-12-17 | 2015-12-08 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological diseases |
| ES2905771T3 (es) | 2015-01-06 | 2022-04-12 | Cellix Bio Private Ltd | Composiciones y procedimientos para el tratamiento de la inflamación y del dolor |
| CN109988085B (zh) * | 2017-12-29 | 2021-11-09 | 张家港市国泰华荣化工新材料有限公司 | 金属离子含量低的1,3-丙二烷基磺酸的制备方法 |
| EP3817810B1 (en) | 2018-07-06 | 2025-09-17 | Pfizer Inc. | Manufacturing process and intermediates for a pyrrolo[2,3- d]pyrimidine compound and use thereof |
| JP7611824B2 (ja) | 2018-11-22 | 2025-01-10 | ナント ユニベルシテ | 増殖性疾患の処置で使用するためのジスルホナートスチルベン |
| JP7324082B2 (ja) * | 2019-08-07 | 2023-08-09 | 東ソー・ファインケム株式会社 | カルボン酸無水物またはスルホン酸無水物の製造方法 |
| CN110818673B (zh) * | 2019-11-22 | 2022-08-16 | 湖南阿斯达新材料有限公司 | 一种环状二磺酸亚甲酯的合成方法 |
| CN112574167B (zh) * | 2020-12-07 | 2021-11-09 | 烟台海川化学制品有限公司 | 一种甲烷二磺酸亚甲酯的制备方法 |
| KR20240001118A (ko) * | 2021-05-31 | 2024-01-03 | 미쯔비시 가스 케미칼 컴파니, 인코포레이티드 | 신규 아미노 화합물 및 그의 제조방법, 그리고, 이것을 이용한 에폭시 수지용 경화제, 에폭시 수지 조성물 및 에폭시 수지 경화물 |
| CN115124502B (zh) * | 2022-08-03 | 2024-09-13 | 张家港市国泰华荣化工新材料有限公司 | 一种丙烯二磺酸酐的制备方法 |
Family Cites Families (31)
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|---|---|---|---|---|
| GB661537A (en) * | 1948-11-24 | 1951-11-21 | Rhone Poulenc Sa | Improvements in and relating to the preparation of sulphonyl derivatives of piperazine |
| BE795839A (fr) | 1972-02-25 | 1973-08-23 | Ciba Geigy | Procede de retification de colloides hydrophiles |
| DD119040A1 (enExample) | 1975-03-11 | 1976-04-05 | ||
| DE2547590A1 (de) * | 1975-10-24 | 1977-04-28 | Agfa Gevaert Ag | Neue 1-sulfonyl-4-amino-pyridiniumsalze und verfahren zu ihrer herstellung |
| US4914091A (en) * | 1984-04-02 | 1990-04-03 | American Cyanamid Company | Esters of cephalosporin derivitives |
| TW211080B (enExample) * | 1991-12-12 | 1993-08-11 | American Telephone & Telegraph | |
| CA2107644A1 (en) * | 1992-10-28 | 1994-04-29 | David R. Magnin | .alpha.-phosphonosulfonae squalene synthetase inhibitors and methd |
| DE4302681A1 (de) * | 1993-02-01 | 1994-08-04 | Hoechst Ag | Sulfonsäureester, damit hergestellte strahlungsempfindliche Gemische und deren Verwendung |
| US5840294A (en) | 1993-03-29 | 1998-11-24 | Queen's University At Kingston | Method for treating amyloidosis |
| EP0691844A1 (en) | 1993-03-29 | 1996-01-17 | Queen's University At Kingston | Method for treating amyloidosis |
| DE19823722A1 (de) * | 1998-05-27 | 1999-12-02 | Merckle Gmbh | Chinolinylmethoxyaryl-Verbindungen als duale Inhibitoren der Cyclooxygenase und 5-Lipoxygenase |
| US6562836B1 (en) | 1999-05-24 | 2003-05-13 | Queen's University Of Kingston | Methods and compounds for inhibiting amyloid deposits |
| BR0016652A (pt) * | 1999-12-23 | 2002-11-19 | Neurochem Inc | Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduo |
| AU2003302109A1 (en) * | 2002-11-21 | 2004-06-15 | Ranbaxy Laboratories Limited | Prodrug esters of ceftriaxone |
| US20050031651A1 (en) * | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| EP1646659B1 (en) * | 2003-06-23 | 2014-05-14 | Kiacta Sàrl | Method for the preparation of 1,3-propane disulfonic acid compounds |
| AU2004249529A1 (en) | 2003-06-23 | 2004-12-29 | Bellus Health (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7253306B2 (en) * | 2003-06-23 | 2007-08-07 | Neurochem (International) Limited | Pharmaceutical drug candidates and methods for preparation thereof |
| JP4484681B2 (ja) * | 2004-12-03 | 2010-06-16 | 富士フイルム株式会社 | 感光性組成物及び該感光性組成物を用いたパターン形成方法 |
| TW200716088A (en) | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| ES2348997T3 (es) * | 2005-08-25 | 2010-12-21 | Schering Corporation | Compuestos de 3,4-dihidro-2h-benzo[1,4]oxazina y 3,4-dihidro-2h-benzo[1,4]tiazina como agonistas del adrenorreceptor alfa2c. |
| GB0523040D0 (en) * | 2005-11-11 | 2005-12-21 | Cyclacel Ltd | Combination |
| ATE481094T1 (de) | 2005-12-22 | 2010-10-15 | Kiacta Sarl | Behandlung von diabetischer nephropathie |
| PE20080940A1 (es) * | 2006-06-28 | 2008-07-09 | Pfizer Prod Inc | Profarmacos de penem |
| JP2010513219A (ja) * | 2006-12-22 | 2010-04-30 | ベラス ヘルス （インターナショナル） リミテッド | 腎臓の疾患、糖尿病性腎症及び脂質代謝異常の治療 |
| CA2673022A1 (en) | 2006-12-22 | 2008-07-03 | Bellus Health (International) Limited | Methods, compounds, and compositions for treating metabolic disorders and diabetes |
| WO2009033079A1 (en) * | 2007-09-07 | 2009-03-12 | Xenoport, Inc. | Externally masked neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use |
| TW200924746A (en) | 2007-09-07 | 2009-06-16 | Xenoport Inc | Complex pantoic acid ester neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use |
| US20090099253A1 (en) | 2007-10-15 | 2009-04-16 | Xenoport, Inc. | Internally Masked Neopentyl Sulfonyl Ester Cyclization Release Prodrugs of Acamprosate, Compositions Thereof, and Methods of Use |
| JP4961324B2 (ja) | 2007-10-26 | 2012-06-27 | 富士フイルム株式会社 | 電子線、ｘ線又はｅｕｖ用ポジ型レジスト組成物及びそれを用いたパターン形成方法 |
| CN102471248B (zh) * | 2009-08-10 | 2015-01-07 | Bhi有限合伙公司 | 用于递送1,3-丙二磺酸的方法、化合物和组合物 |
-
2010
- 2010-08-06 CN CN201080032065.4A patent/CN102471248B/zh not_active Expired - Fee Related
- 2010-08-06 WO PCT/CA2010/001229 patent/WO2011017800A1/en not_active Ceased
- 2010-08-06 MX MX2012001671A patent/MX2012001671A/es active IP Right Grant
- 2010-08-06 KR KR1020127002219A patent/KR20120087878A/ko not_active Ceased
- 2010-08-06 SG SG10201600910YA patent/SG10201600910YA/en unknown
- 2010-08-06 NZ NZ598085A patent/NZ598085A/en not_active IP Right Cessation
- 2010-08-06 JP JP2012524066A patent/JP2013501733A/ja not_active Ceased
- 2010-08-06 EP EP10807830.4A patent/EP2464626A4/en not_active Withdrawn
- 2010-08-06 CA CA2768877A patent/CA2768877A1/en not_active Abandoned
- 2010-08-06 AU AU2010282170A patent/AU2010282170B2/en not_active Ceased
- 2010-08-06 US US13/389,606 patent/US9051248B2/en not_active Expired - Fee Related
- 2010-08-06 EA EA201290007A patent/EA201290007A1/ru unknown
- 2010-08-06 SG SG2012002515A patent/SG177645A1/en unknown
- 2010-08-06 BR BR112012002780A patent/BR112012002780A2/pt active Search and Examination
-
2012
- 2012-01-16 IL IL217572A patent/IL217572A/en active IP Right Grant
- 2012-02-23 ZA ZA2012/01352A patent/ZA201201352B/en unknown
-
2015
- 2015-05-08 US US14/707,472 patent/US20150266814A1/en not_active Abandoned
- 2015-09-11 JP JP2015179480A patent/JP2016034960A/ja active Pending