CN102471248B - 用于递送1,3-丙二磺酸的方法、化合物和组合物 - Google Patents
用于递送1,3-丙二磺酸的方法、化合物和组合物 Download PDFInfo
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- CN102471248B CN102471248B CN201080032065.4A CN201080032065A CN102471248B CN 102471248 B CN102471248 B CN 102471248B CN 201080032065 A CN201080032065 A CN 201080032065A CN 102471248 B CN102471248 B CN 102471248B
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- 0 *CC([C@](Cc1ccccc1)NCc1ccccc1)=O Chemical compound *CC([C@](Cc1ccccc1)NCc1ccccc1)=O 0.000 description 6
- WMBITDWQXIGGGR-UHFFFAOYSA-N CC(C)(CCOC(c1ccccc1)O)COS(CCCS(OCC(C)(C)CCOC(c1ccccc1)=O)(=O)=O)(=O)=O Chemical compound CC(C)(CCOC(c1ccccc1)O)COS(CCCS(OCC(C)(C)CCOC(c1ccccc1)=O)(=O)=O)(=O)=O WMBITDWQXIGGGR-UHFFFAOYSA-N 0.000 description 1
- UGPSTOZUXXGCFT-UHFFFAOYSA-N CC(C)(CNI)CO Chemical compound CC(C)(CNI)CO UGPSTOZUXXGCFT-UHFFFAOYSA-N 0.000 description 1
- YLQUPSUHNNYAOQ-MDYZWHIJSA-O CC(C)(C[NH+](C[C@H](Cc1ccccc1)N)[O-])CO/S(/CC/C=S(/O)\[OH2+])=C\C Chemical compound CC(C)(C[NH+](C[C@H](Cc1ccccc1)N)[O-])CO/S(/CC/C=S(/O)\[OH2+])=C\C YLQUPSUHNNYAOQ-MDYZWHIJSA-O 0.000 description 1
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- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
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- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
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- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/06—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by carboxyl groups
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- Animal Behavior & Ethology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23259709P | 2009-08-10 | 2009-08-10 | |
| US61/232,597 | 2009-08-10 | ||
| PCT/CA2010/001229 WO2011017800A1 (en) | 2009-08-10 | 2010-08-06 | Methods, compounds, and compositions for delivering 1,3-propan ed isulfonic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102471248A CN102471248A (zh) | 2012-05-23 |
| CN102471248B true CN102471248B (zh) | 2015-01-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080032065.4A Expired - Fee Related CN102471248B (zh) | 2009-08-10 | 2010-08-06 | 用于递送1,3-丙二磺酸的方法、化合物和组合物 |
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| US (2) | US9051248B2 (enExample) |
| EP (1) | EP2464626A4 (enExample) |
| JP (2) | JP2013501733A (enExample) |
| KR (1) | KR20120087878A (enExample) |
| CN (1) | CN102471248B (enExample) |
| AU (1) | AU2010282170B2 (enExample) |
| BR (1) | BR112012002780A2 (enExample) |
| CA (1) | CA2768877A1 (enExample) |
| EA (1) | EA201290007A1 (enExample) |
| IL (1) | IL217572A (enExample) |
| MX (1) | MX2012001671A (enExample) |
| NZ (1) | NZ598085A (enExample) |
| SG (2) | SG177645A1 (enExample) |
| WO (1) | WO2011017800A1 (enExample) |
| ZA (1) | ZA201201352B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| SG177645A1 (en) * | 2009-08-10 | 2012-02-28 | Bellus Health Inc | Methods, compounds, and compositions for delivering 1,3-propan ed isulfonic acid |
| WO2011107870A2 (en) * | 2010-03-05 | 2011-09-09 | Mahesh Kandula | Compounds and compositions and their use in the treatment of diseases related to copper retention |
| WO2014037832A2 (en) | 2012-09-06 | 2014-03-13 | Mahesh Kandula | Compositions and methods for the treatment of epilepsy and neurological diseases |
| WO2013167990A1 (en) | 2012-05-07 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of depression |
| SG11201407300VA (en) | 2012-05-07 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of neurological disorders |
| CA2873093A1 (en) | 2012-05-07 | 2013-11-14 | Cellixbio Private Limited | Compositions and methods for treatment of neuromuscular disorders and neurodegenerative disorders |
| WO2013168025A1 (en) | 2012-05-08 | 2013-11-14 | Mahesh Kandula | Compositions and methods for treatment of blood clotting disorders |
| US9434704B2 (en) | 2012-05-08 | 2016-09-06 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological degenerative disorders |
| WO2013167991A1 (en) | 2012-05-08 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of metabolic disorders |
| US9266823B2 (en) | 2012-05-08 | 2016-02-23 | Cellix Bio Private Limited | Compositions and methods for the treatment of parkinson's disease |
| US9403826B2 (en) | 2012-05-08 | 2016-08-02 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory disorders |
| US9242939B2 (en) | 2012-05-10 | 2016-01-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of respiratory disorders |
| WO2013168014A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of familial amyloid polyneuropathy |
| WO2013168011A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of chronic pain |
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Also Published As
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| CN102471248A (zh) | 2012-05-23 |
| NZ598085A (en) | 2014-02-28 |
| US9051248B2 (en) | 2015-06-09 |
| AU2010282170B2 (en) | 2015-04-23 |
| WO2011017800A1 (en) | 2011-02-17 |
| IL217572A (en) | 2015-05-31 |
| EP2464626A1 (en) | 2012-06-20 |
| BR112012002780A2 (pt) | 2017-02-21 |
| MX2012001671A (es) | 2012-04-30 |
| SG10201600910YA (en) | 2016-03-30 |
| US20150266814A1 (en) | 2015-09-24 |
| SG177645A1 (en) | 2012-02-28 |
| AU2010282170A1 (en) | 2012-03-01 |
| EA201290007A1 (ru) | 2013-01-30 |
| JP2013501733A (ja) | 2013-01-17 |
| CA2768877A1 (en) | 2011-02-17 |
| ZA201201352B (en) | 2014-04-30 |
| JP2016034960A (ja) | 2016-03-17 |
| EP2464626A4 (en) | 2015-12-16 |
| KR20120087878A (ko) | 2012-08-07 |
| US20120208850A1 (en) | 2012-08-16 |
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