JP2010511019A5 - - Google Patents
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- Publication number
- JP2010511019A5 JP2010511019A5 JP2009538726A JP2009538726A JP2010511019A5 JP 2010511019 A5 JP2010511019 A5 JP 2010511019A5 JP 2009538726 A JP2009538726 A JP 2009538726A JP 2009538726 A JP2009538726 A JP 2009538726A JP 2010511019 A5 JP2010511019 A5 JP 2010511019A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- compound
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86814906P | 2006-12-01 | 2006-12-01 | |
| US99474007P | 2007-09-21 | 2007-09-21 | |
| PCT/EP2007/063108 WO2008065199A1 (en) | 2006-12-01 | 2007-11-30 | Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010511019A JP2010511019A (ja) | 2010-04-08 |
| JP2010511019A5 true JP2010511019A5 (enExample) | 2010-12-09 |
Family
ID=39047973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009538726A Pending JP2010511019A (ja) | 2006-12-01 | 2007-11-30 | 変性疾患及び炎症性疾患の治療に有用なイミダゾロピリジン化合物 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7951818B2 (enExample) |
| EP (1) | EP2099798A1 (enExample) |
| JP (1) | JP2010511019A (enExample) |
| WO (1) | WO2008065199A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE495743T1 (de) * | 2006-12-01 | 2011-02-15 | Galapagos Nv | Triazolopyridinverbindungen zur behandlung von degenerations- und entzündungskrankheiten |
| US7951818B2 (en) * | 2006-12-01 | 2011-05-31 | Galapagos Nv | Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases |
| WO2010044054A1 (en) * | 2008-10-14 | 2010-04-22 | Actelion Pharmaceuticals Ltd | Phenethylamide derivatives and their heterocyclic analogues |
| KR101743784B1 (ko) | 2008-12-08 | 2017-06-05 | 질레드 코네티컷 인코포레이티드 | 이미다조피라진 ｓｙｋ 억제제 |
| PA8854101A1 (es) * | 2008-12-18 | 2010-07-27 | Ortho Mcneil Janssen Pharm | Derivados de imidazol bicíclicos sustituidos como moduladores de gamma secretasa |
| CN102325765B (zh) | 2009-02-06 | 2014-12-24 | 杨森制药公司 | 作为γ-分泌酶调节剂的取代的双环杂环化合物 |
| TWI461425B (zh) | 2009-02-19 | 2014-11-21 | Janssen Pharmaceuticals Inc | 作為伽瑪分泌酶調節劑之新穎經取代的苯并唑、苯并咪唑、唑并吡啶及咪唑并吡啶衍生物類 |
| CA2755467A1 (en) | 2009-05-07 | 2010-12-23 | Janssen Pharmaceuticals, Inc. | Novel substituted indazole and aza-indazole derivatives as gamma secretase modulators |
| BR112012000915A2 (pt) | 2009-07-15 | 2019-09-24 | Janssen Pharmaceuticals Inc | derivados de triazol e imidazol substituídos como moduladores de gama secretase. |
| AU2011206635B2 (en) | 2010-01-15 | 2015-01-22 | Cellzome Limited | Novel substituted triazole derivatives as gamma secretase modulators |
| ES2530449T3 (es) * | 2010-03-11 | 2015-03-02 | Gilead Connecticut Inc | Inhibidores de Syk de imidazopiridinas |
| AU2012230348A1 (en) | 2011-03-24 | 2013-08-29 | Cellzome Limited | Novel substituted triazolyl piperazine and triazolyl piperidine derivatives as gamma secretase modulators |
| ES2555167T3 (es) | 2011-07-15 | 2015-12-29 | Janssen Pharmaceuticals, Inc. | Nuevos derivados de indol sustituidos como moduladores de gamma secretasa |
| CN104583208B (zh) | 2012-05-16 | 2016-09-28 | 杨森制药公司 | 可用于治疗(尤其是)阿尔茨海默病的取代的3,4-二氢-2H-吡啶并[1,2-a]吡嗪-1,6-二酮衍生物 |
| AU2013366668B2 (en) | 2012-12-20 | 2017-07-20 | Janssen Pharmaceutica Nv | Novel tricyclic 3,4-dihydro-2H-pyrido[1,2-alpha]pyrazine -1,6-dione derivatives as gamma secretase modulators |
| AU2014206834B2 (en) | 2013-01-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Novel substituted pyrido-piperazinone derivatives as gamma secretase modulators |
| US10562897B2 (en) | 2014-01-16 | 2020-02-18 | Janssen Pharmaceutica Nv | Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators |
| CN107129496A (zh) * | 2017-06-02 | 2017-09-05 | 贵州大学 | 一种8‑碘‑6‑硝基‑咪唑并[1,2‑a]吡啶的制备工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9802794D0 (sv) * | 1998-08-21 | 1998-08-21 | Astra Ab | New compounds |
| AU2003249477A1 (en) * | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Heterobicylcic metalloproteinase inhibitors |
| DE60317529T2 (de) * | 2002-09-19 | 2008-09-25 | Schering Corp. | Imidazopyridine als hemmstoffe cyclin abhängiger kinasen |
| WO2006004702A1 (en) * | 2004-06-25 | 2006-01-12 | Amgen Inc. | Condensed triazoles and indazoles useful in treating citokines mediated diseases and other diseases |
| US7893058B2 (en) | 2006-05-15 | 2011-02-22 | Janssen Pharmaceutica Nv | Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
| US7951818B2 (en) * | 2006-12-01 | 2011-05-31 | Galapagos Nv | Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases |
-
2007
- 2007-11-30 US US11/998,818 patent/US7951818B2/en not_active Expired - Fee Related
- 2007-11-30 WO PCT/EP2007/063108 patent/WO2008065199A1/en not_active Ceased
- 2007-11-30 EP EP07847622A patent/EP2099798A1/en not_active Withdrawn
- 2007-11-30 JP JP2009538726A patent/JP2010511019A/ja active Pending
-
2011
- 2011-05-25 US US13/115,977 patent/US20120010206A1/en not_active Abandoned
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