JP2010511019A5 - - Google Patents
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- Publication number
- JP2010511019A5 JP2010511019A5 JP2009538726A JP2009538726A JP2010511019A5 JP 2010511019 A5 JP2010511019 A5 JP 2010511019A5 JP 2009538726 A JP2009538726 A JP 2009538726A JP 2009538726 A JP2009538726 A JP 2009538726A JP 2010511019 A5 JP2010511019 A5 JP 2010511019A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- compound
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86814906P | 2006-12-01 | 2006-12-01 | |
| US99474007P | 2007-09-21 | 2007-09-21 | |
| PCT/EP2007/063108 WO2008065199A1 (en) | 2006-12-01 | 2007-11-30 | Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010511019A JP2010511019A (ja) | 2010-04-08 |
| JP2010511019A5 true JP2010511019A5 (enExample) | 2010-12-09 |
Family
ID=39047973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009538726A Pending JP2010511019A (ja) | 2006-12-01 | 2007-11-30 | 変性疾患及び炎症性疾患の治療に有用なイミダゾロピリジン化合物 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7951818B2 (enExample) |
| EP (1) | EP2099798A1 (enExample) |
| JP (1) | JP2010511019A (enExample) |
| WO (1) | WO2008065199A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010511018A (ja) * | 2006-12-01 | 2010-04-08 | ガラパゴス・ナムローゼ・フェンノートシャップ | 変性疾患及び炎症性疾患の治療に有用なトリアゾロピリジン化合物 |
| US7951818B2 (en) * | 2006-12-01 | 2011-05-31 | Galapagos Nv | Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases |
| AU2009305005A1 (en) * | 2008-10-14 | 2010-04-22 | Actelion Pharmaceuticals Ltd | Phenethylamide derivatives and their heterocyclic analogues |
| EP3552607A3 (en) | 2008-12-08 | 2020-01-15 | Gilead Connecticut, Inc. | Imidazopyrazine syk inhibitors |
| PA8854101A1 (es) * | 2008-12-18 | 2010-07-27 | Ortho Mcneil Janssen Pharm | Derivados de imidazol bicíclicos sustituidos como moduladores de gamma secretasa |
| US8946426B2 (en) | 2009-02-06 | 2015-02-03 | Janssen Pharmaceuticals, Inc. | Substituted bicyclic heterocyclic compounds as gamma secretase modulators |
| TWI461425B (zh) | 2009-02-19 | 2014-11-21 | Janssen Pharmaceuticals Inc | 作為伽瑪分泌酶調節劑之新穎經取代的苯并唑、苯并咪唑、唑并吡啶及咪唑并吡啶衍生物類 |
| ES2431619T3 (es) | 2009-05-07 | 2013-11-27 | Janssen Pharmaceuticals, Inc. | Derivados de indazol y aza-indazol sustituidos como moduladores de gamma-secretasa |
| NZ597505A (en) | 2009-07-15 | 2013-05-31 | Janssen Pharmaceuticals Inc | Substituted triazole and imidazole derivatives as gamma secretase modulators |
| US9145399B2 (en) | 2010-01-15 | 2015-09-29 | Janssen Pharmaceuticals, Inc. | Substituted bicyclic triazole derivatives as gamma secretase modulators |
| US9562056B2 (en) * | 2010-03-11 | 2017-02-07 | Gilead Connecticut, Inc. | Imidazopyridines Syk inhibitors |
| ES2536442T3 (es) | 2011-03-24 | 2015-05-25 | Janssen Pharmaceuticals, Inc. | Derivados novedosos de triazolil piperazina y triazolil piperidina como moduladores de la gamma secretasa |
| JP6068464B2 (ja) | 2011-07-15 | 2017-01-25 | ヤンセン ファーマシューティカルズ，インコーポレーテッド | γ−セクレターゼ調節剤としての新規な置換インドール誘導体 |
| ES2585009T3 (es) | 2012-05-16 | 2016-10-03 | Janssen Pharmaceuticals, Inc. | Derivados de 3,4-dihidro-2H-pirido[1,2-a]pirazina-1,6-diona sustituidos útiles para el tratamiento de (inter alia) enfermedad de Alzheimer |
| CA2889249C (en) | 2012-12-20 | 2021-02-16 | Francois Paul Bischoff | Tricyclic 3,4-dihydro-2h-pyrido[1,2-a]pyrazine-1,6-dione derivatives as gamma secretase modulators |
| AU2014206834B2 (en) | 2013-01-17 | 2017-06-22 | Janssen Pharmaceutica Nv | Novel substituted pyrido-piperazinone derivatives as gamma secretase modulators |
| US10562897B2 (en) | 2014-01-16 | 2020-02-18 | Janssen Pharmaceutica Nv | Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators |
| CN107129496A (zh) * | 2017-06-02 | 2017-09-05 | 贵州大学 | 一种8‑碘‑6‑硝基‑咪唑并[1,2‑a]吡啶的制备工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9802794D0 (sv) * | 1998-08-21 | 1998-08-21 | Astra Ab | New compounds |
| WO2004014908A1 (en) * | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Heterobicylcic metalloproteinase inhibitors |
| AR041291A1 (es) | 2002-09-19 | 2005-05-11 | Schering Corp | Imidazopiridinas como inhibidores de quinasa dependientes de ciclina |
| MXPA06014637A (es) * | 2004-06-25 | 2007-02-12 | Amgen Inc | Triazoles e indazoles condensados utiles en el tratamiento de enfermedades mediadas por citocinas y otras enfermedades. |
| US7893058B2 (en) | 2006-05-15 | 2011-02-22 | Janssen Pharmaceutica Nv | Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
| US7951818B2 (en) * | 2006-12-01 | 2011-05-31 | Galapagos Nv | Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases |
-
2007
- 2007-11-30 US US11/998,818 patent/US7951818B2/en not_active Expired - Fee Related
- 2007-11-30 EP EP07847622A patent/EP2099798A1/en not_active Withdrawn
- 2007-11-30 WO PCT/EP2007/063108 patent/WO2008065199A1/en not_active Ceased
- 2007-11-30 JP JP2009538726A patent/JP2010511019A/ja active Pending
-
2011
- 2011-05-25 US US13/115,977 patent/US20120010206A1/en not_active Abandoned
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