JP2012533587A - 自然に存在する細胞内輸送経路を介して化合物を送達するための送達システム及びコンジュゲート - Google Patents

自然に存在する細胞内輸送経路を介して化合物を送達するための送達システム及びコンジュゲート Download PDF

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JP2012533587A
JP2012533587A JP2012520958A JP2012520958A JP2012533587A JP 2012533587 A JP2012533587 A JP 2012533587A JP 2012520958 A JP2012520958 A JP 2012520958A JP 2012520958 A JP2012520958 A JP 2012520958A JP 2012533587 A JP2012533587 A JP 2012533587A
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ジェイ． エチェベリ，クリストフィー
ゾニンシェセン，ビルテ
ウォーラー，ラインハルト
ウェルナー エルムス，マイク
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セニックス バイオサイエンス ゲーエムベーハー
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JP2012520958A 2009-07-22 2010-07-22 自然に存在する細胞内輸送経路を介して化合物を送達するための送達システム及びコンジュゲート Pending JP2012533587A (ja)

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US22766909P 2009-07-22 2009-07-22
US61/227,669 2009-07-22
PCT/EP2010/004512 WO2011009624A1 (en) 2009-07-22 2010-07-22 Delivery system and conjugates for compound delivery via naturally occurring intracellular transport routes

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JP2012533587A true JP2012533587A (ja) 2012-12-27
JP2012533587A5 JP2012533587A5 (https=) 2013-09-12

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US (1) US20120258104A1 (https=)
EP (1) EP2456470A1 (https=)
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CA (1) CA2768598A1 (https=)
WO (1) WO2011009624A1 (https=)

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JP2014505064A (ja) * 2011-01-26 2014-02-27 セニックス バイオサイエンス ゲーエムベーハー 自然に存在する細胞内輸送経路を介して化合物を送達するための送達システム及びコンジュゲート
JP2017513459A (ja) * 2014-03-11 2017-06-01 モレキュラー テンプレーツ, インク.Molecular Templates, Inc. 結合領域、志賀毒素ａサブユニットのエフェクター領域、及びカルボキシ末端小胞体局在化シグナルモチーフを含むタンパク質
JP2017534598A (ja) * 2014-09-30 2017-11-24 ザ メディカル カレッジ オブ ウィスコンシン インクＴｈｅ Ｍｅｄｉｃａｌ Ｃｏｌｌｅｇｅ Ｏｆ Ｗｉｓｃｏｎｓｉｎ， Ｉｎｃ． 神経系疾患を治療する標的療法のための汎用的なプラットフォーム
JP2018529386A (ja) * 2015-10-05 2018-10-11 シンジェンタ パーティシペーションズ アーゲー リボ核酸の生物活性を保存する方法
US11389542B1 (en) 2016-12-07 2022-07-19 Molecular Templates, Inc. Shiga toxin a subunit effector polypeptides, Shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
US12037367B2 (en) 2014-01-27 2024-07-16 Molecular Templates, Inc. MHC class I epitope delivering polypeptides

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