JP2012525855A5 - - Google Patents

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JP2012525855A5
JP2012525855A5 JP2012510038A JP2012510038A JP2012525855A5 JP 2012525855 A5 JP2012525855 A5 JP 2012525855A5 JP 2012510038 A JP2012510038 A JP 2012510038A JP 2012510038 A JP2012510038 A JP 2012510038A JP 2012525855 A5 JP2012525855 A5 JP 2012525855A5
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sample
dna
thyroid
complements
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JP2012525855A (ja
JP6078339B2 (ja
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JP2012510038A 2009-05-07 2010-05-07 甲状腺状態の診断のための方法および組成物 Active JP6078339B2 (ja)

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Application Number Priority Date Filing Date Title
US17647109P 2009-05-07 2009-05-07
US61/176,471 2009-05-07
PCT/US2010/034140 WO2010129934A2 (en) 2009-05-07 2010-05-07 Methods and compositions for diagnosis of thyroid conditions

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JP2015153185A Division JP2016005471A (ja) 2009-05-07 2015-08-03 甲状腺状態の診断のための方法および組成物

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JP2012525855A JP2012525855A (ja) 2012-10-25
JP2012525855A5 true JP2012525855A5 (OSRAM) 2013-06-20
JP6078339B2 JP6078339B2 (ja) 2017-02-08

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JP2012510038A Active JP6078339B2 (ja) 2009-05-07 2010-05-07 甲状腺状態の診断のための方法および組成物
JP2015153185A Withdrawn JP2016005471A (ja) 2009-05-07 2015-08-03 甲状腺状態の診断のための方法および組成物
JP2017212332A Active JP6684775B2 (ja) 2009-05-07 2017-11-02 甲状腺状態の診断のための方法および組成物
JP2020059973A Withdrawn JP2020108402A (ja) 2009-05-07 2020-03-30 甲状腺状態の診断のための方法および組成物

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JP2015153185A Withdrawn JP2016005471A (ja) 2009-05-07 2015-08-03 甲状腺状態の診断のための方法および組成物
JP2017212332A Active JP6684775B2 (ja) 2009-05-07 2017-11-02 甲状腺状態の診断のための方法および組成物
JP2020059973A Withdrawn JP2020108402A (ja) 2009-05-07 2020-03-30 甲状腺状態の診断のための方法および組成物

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US (4) US8669057B2 (OSRAM)
EP (2) EP2427575B1 (OSRAM)
JP (4) JP6078339B2 (OSRAM)
CN (1) CN102459636B (OSRAM)
WO (1) WO2010129934A2 (OSRAM)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008058018A2 (en) 2006-11-02 2008-05-15 Mayo Foundation For Medical Education And Research Predicting cancer outcome
EP2806054A1 (en) 2008-05-28 2014-11-26 Genomedx Biosciences Inc. Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
US10407731B2 (en) 2008-05-30 2019-09-10 Mayo Foundation For Medical Education And Research Biomarker panels for predicting prostate cancer outcomes
GB2512153B (en) * 2008-11-17 2014-11-12 Veracyte Inc Methods and compositions of molecular profiling for disease diagnostics
US9495515B1 (en) 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
US9074258B2 (en) 2009-03-04 2015-07-07 Genomedx Biosciences Inc. Compositions and methods for classifying thyroid nodule disease
JP6078339B2 (ja) 2009-05-07 2017-02-08 ベラサイト インコーポレイテッド 甲状腺状態の診断のための方法および組成物
US10446272B2 (en) 2009-12-09 2019-10-15 Veracyte, Inc. Methods and compositions for classification of samples
US20130267443A1 (en) 2010-11-19 2013-10-10 The Regents Of The University Of Michigan ncRNA AND USES THEREOF
US8945829B2 (en) 2011-03-22 2015-02-03 Cornell University Distinguishing benign and malignant indeterminate thyroid lesions
WO2013082123A2 (en) * 2011-11-28 2013-06-06 University Of Chicago Method, system, software and medium for advanced image-based arrays for analysis and display of biomedical information
WO2013086524A1 (en) * 2011-12-09 2013-06-13 The Johns Hopkins University Compositions and methods for characterizing thyroid neoplasia
WO2013090620A1 (en) 2011-12-13 2013-06-20 Genomedx Biosciences, Inc. Cancer diagnostics using non-coding transcripts
ES2945036T3 (es) 2012-08-16 2023-06-28 Veracyte Sd Inc Pronóstico del cáncer de próstata mediante biomarcadores
WO2014081923A1 (en) * 2012-11-21 2014-05-30 The Johns Hopkins University Genomic classifiers for non-invasive identification of high grade prostate cancer with metastatic potential
EP2925886B1 (en) * 2012-11-27 2019-04-24 Pontificia Universidad Católica de Chile Compositions and methods for diagnosing thyroid tumors
JP6644328B2 (ja) * 2013-02-28 2020-02-12 ロート製薬株式会社 アトピー性疾患の発症又は重症化リスクの評価法
WO2014151764A2 (en) * 2013-03-15 2014-09-25 Veracyte, Inc. Methods and compositions for classification of samples
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
CN105431552B (zh) * 2013-04-12 2020-03-03 香港中文大学 多组学标记在预测糖尿病中的用途
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
WO2016057629A1 (en) * 2014-10-07 2016-04-14 Duke University Methods and therapeutics relating to human r-spondin protein and leucine-rich repeat-containing g protein-coupled receptor protein
EP3770274A1 (en) 2014-11-05 2021-01-27 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
CN104845970B (zh) * 2015-05-13 2017-10-10 亳州市新健康科技有限公司 与乳头状甲状腺瘤相关的基因
JP6826051B2 (ja) * 2015-06-12 2021-02-03 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 被験者の活動期間と非活動期間とを識別するための装置、システム、方法及びコンピュータプログラム
US11756655B2 (en) * 2015-10-09 2023-09-12 Guardant Health, Inc. Population based treatment recommender using cell free DNA
CN105385781B (zh) * 2015-12-29 2019-08-13 北京泱深生物信息技术有限公司 Lce3e在诊治口腔癌中的应用
JP6428655B2 (ja) 2016-01-14 2018-11-28 株式会社デンソー 電子キーシステム、車載機、および電子キー
US11414708B2 (en) 2016-08-24 2022-08-16 Decipher Biosciences, Inc. Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy
AU2018210695B2 (en) 2017-01-20 2024-07-18 The University Of British Columbia Molecular subtyping, prognosis, and treatment of bladder cancer
US11873532B2 (en) 2017-03-09 2024-01-16 Decipher Biosciences, Inc. Subtyping prostate cancer to predict response to hormone therapy
WO2018205035A1 (en) 2017-05-12 2018-11-15 Genomedx Biosciences, Inc Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness
US11217329B1 (en) 2017-06-23 2022-01-04 Veracyte, Inc. Methods and systems for determining biological sample integrity
JP6965621B2 (ja) * 2017-08-02 2021-11-10 富士通株式会社 検出プログラム、検出方法及び検出装置
JP7098373B2 (ja) * 2018-03-26 2022-07-11 株式会社三共 スロットマシン
WO2019218338A1 (zh) * 2018-05-18 2019-11-21 立森印迹诊断技术有限公司 通过活检细胞样本诊断癌症的方法
JP7152734B2 (ja) * 2018-06-28 2022-10-13 ネット株式会社 遊技機
CN109762902B (zh) * 2018-07-27 2022-07-05 四川大学华西医院 一种人类map2k5第1100位碱基突变基因的arms-pcr检测试剂盒
CN109652552B (zh) * 2018-07-27 2022-07-05 四川大学华西医院 一种人类map2k5第961位碱基突变基因的arms-pcr检测试剂盒
US20220137053A1 (en) * 2019-01-30 2022-05-05 Arizona Board Of Regents On Behalf Of The University Of Arizona Lipid biomarkers for cancer screening and monitoring
JP7568423B2 (ja) * 2019-05-10 2024-10-16 キヤノンメディカルシステムズ株式会社 診断支援装置
CN111292801A (zh) * 2020-01-21 2020-06-16 西湖大学 蛋白质质谱结合深度学习评估甲状腺结节的方法
EP4317458A4 (en) * 2021-03-30 2025-03-05 Nippon Medical School Foundation FOLLICULAR THYROID CANCER-SPECIFIC MARKER
CN115558714A (zh) * 2021-07-01 2023-01-03 上海鹍远生物科技股份有限公司 甲状腺结节良恶性相关标志物及其应用
US12207935B2 (en) * 2021-07-02 2025-01-28 The Board Of Trustees Of Western Michigan University Quantitative image-based disorder analysis for early detection of melanoma type features
CN115927610B (zh) * 2022-07-19 2024-11-05 武汉艾米森生命科技有限公司 检测foxo6基因中目标区域的甲基化水平的试剂在制备膀胱癌诊断产品中的应用
WO2025009415A1 (ja) * 2023-07-03 2025-01-09 ユニバーサル・バイオ・リサーチ株式会社 品質測定装置、及び検体処理システム

Family Cites Families (331)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640268A (en) 1965-10-23 1972-02-08 Hugh J Davis Method and device for biopsy specimen collecting and handling
AT277936B (de) 1968-02-27 1970-01-12 Guenter Dipl Ing Knapp Verfahren zur quantitativen Bestimmung von Jod und von Schilddrüsenhormonen sowie Vorrichtung zur Durchführung des Verfahrens
US3687808A (en) 1969-08-14 1972-08-29 Univ Leland Stanford Junior Synthetic polynucleotides
US4641662A (en) 1984-09-28 1987-02-10 Jaicks John R Endocervical curette system
US4800896A (en) 1985-11-08 1989-01-31 Jalowayski Alfredo A Cell sample collector probe
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
US5798257A (en) 1990-07-09 1998-08-25 Research Corporation Technologies, Inc. Nucleic acid encoding human MTS-1 protein
DE69132531T2 (de) 1990-12-06 2001-09-13 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Verbindungen und ihre Verwendung in einer binären Synthesestrategie
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5994069A (en) 1996-01-24 1999-11-30 Third Wave Technologies, Inc. Detection of nucleic acids by multiple sequential invasive cleavages
US5726060A (en) 1991-09-17 1998-03-10 Bridges; Michael Anthony Method for culturing mammalian respiratory epithelial cells
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
AU675054B2 (en) 1991-11-22 1997-01-23 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US6027887A (en) 1992-03-11 2000-02-22 Institute Of Virology, Solvak Academy Of Sciences MN gene and protein
US6204370B1 (en) 1992-03-11 2001-03-20 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US5541061A (en) 1992-04-29 1996-07-30 Affymax Technologies N.V. Methods for screening factorial chemical libraries
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5422273A (en) 1993-03-23 1995-06-06 Baal Medical Products, Inc. Cell collection apparatus
US5876978A (en) 1993-04-06 1999-03-02 Medical College Of Ohio Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
US5477863A (en) 1993-04-14 1995-12-26 Grant; Michael A. Collection kit with a sample collector
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
US5529925A (en) 1993-12-03 1996-06-25 St. Jude Children's Research Hospital Nucleic acid sequences and fusion proteins present in human t(2;5) lymphoma
US5440942A (en) 1994-02-02 1995-08-15 Hubbard; Stephen H. Biological sample collecting and holding device
US5989815A (en) 1994-03-18 1999-11-23 University Of Utah Research Foundation Methods for detecting predisposition to cancer at the MTS gene
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US7625697B2 (en) 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US5830753A (en) 1994-09-30 1998-11-03 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof.
US5795782A (en) 1995-03-17 1998-08-18 President & Fellows Of Harvard College Characterization of individual polymer molecules based on monomer-interface interactions
US5705365A (en) 1995-06-07 1998-01-06 Gen-Probe Incorporated Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5710029A (en) 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US6004942A (en) 1995-08-30 1999-12-21 The Regents Of The University Of California Methods for treating arthritis by administering an apoptosis regulator
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US5985557A (en) 1996-01-24 1999-11-16 Third Wave Technologies, Inc. Invasive cleavage of nucleic acids
DE69733629T2 (de) 1996-04-16 2006-05-18 Kishimoto, Tadamitsu, Tondabayashi Verfahren zum nachweis solider krebszellen und histologischer heterotypien und verfahren zur prüfung von gewebe für die knochenmarktransplantation und die transplantation von peripheren blutstammzellen
US6136182A (en) 1996-06-07 2000-10-24 Immunivest Corporation Magnetic devices and sample chambers for examination and manipulation of cells
GB9711040D0 (en) 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
WO1998057145A1 (en) 1997-06-10 1998-12-17 Quadrivium, L.L.C. System and method for detection of a biological condition
JP2006127537A (ja) 1997-09-11 2006-05-18 Canon Inc 印刷制御装置及び方法
US20020076735A1 (en) 1998-09-25 2002-06-20 Williams Lewis T. Diagnostic and therapeutic methods using molecules differentially expressed in cancer cells
US6085907A (en) 1998-05-08 2000-07-11 Institute Of Legal Medicine, University Of Bern Foldable cardboard box for contact-free drying and long-term storage of biological evidence recovered on cotton swabs and forensic evidence collection kit including same
CA2328138A1 (en) 1998-05-21 1999-11-25 Diadexus Llc A novel method of diagnosing, monitoring, and staging lung cancer
EP1092772B1 (en) 1998-06-08 2007-08-08 Fuso Pharmaceutical Industries Ltd. Antibody against lar phosphatase subunit
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
US6468476B1 (en) 1998-10-27 2002-10-22 Rosetta Inpharmatics, Inc. Methods for using-co-regulated genesets to enhance detection and classification of gene expression patterns
DE69940623D1 (de) 1998-11-09 2009-04-30 Eiken Chemical Prozess zur Synthetisierung von Nukleinsäure
US20040241728A1 (en) 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of lung disease related gene transcripts in blood
US6436642B1 (en) 1999-04-20 2002-08-20 Curagen Corporation Method of classifying a thyroid carcinoma using differential gene expression
US7258838B2 (en) 1999-06-22 2007-08-21 President And Fellows Of Harvard College Solid state molecular probe device
JP2003502166A (ja) 1999-06-22 2003-01-21 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ 固体状態の次元的特徴の制御
US6746846B1 (en) 1999-06-30 2004-06-08 Corixa Corporation Methods for diagnosing lung cancer
US6667154B1 (en) 1999-06-30 2003-12-23 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
IL148091A0 (en) 1999-09-13 2002-09-12 Nugen Technologies Inc Methods and compositions for linear isothermal amplification of polynucleotide sequences
US7244559B2 (en) 1999-09-16 2007-07-17 454 Life Sciences Corporation Method of sequencing a nucleic acid
US7211390B2 (en) 1999-09-16 2007-05-01 454 Life Sciences Corporation Method of sequencing a nucleic acid
AU7808500A (en) 1999-10-18 2001-04-30 Denis Marshall-Fraser Sample taking device
US6723506B2 (en) 2000-01-20 2004-04-20 Brigham And Women's Hospital Method of identifying PAX8-PPAR gamma-nucleic acid molecules
US7361488B2 (en) 2000-02-07 2008-04-22 Illumina, Inc. Nucleic acid detection methods using universal priming
US6383804B1 (en) 2000-07-13 2002-05-07 International Bioproducts, Inc. Sampling device with snap-off head and method of use
AU2001281136A1 (en) 2000-08-04 2002-02-18 Board Of Regents, The University Of Texas System Detection and diagnosis of smoking related cancers
US20020160388A1 (en) 2000-11-20 2002-10-31 Roberto Macina Compositions and methods relating to lung specific genes and proteins
WO2002044331A2 (en) 2000-11-29 2002-06-06 Cangen International Dap-kinase and hoxa9, two human genes associated with genesis, progression, and aggressiveness of non-small cell lung cancer
US6988040B2 (en) 2001-01-11 2006-01-17 Affymetrix, Inc. System, method, and computer software for genotyping analysis and identification of allelic imbalance
US6972181B2 (en) 2001-01-12 2005-12-06 Mount Sinai School Of Medicine Of New York University Differential diagnosis of cancer and other conditions based on expression of p63
WO2003040325A2 (en) 2001-02-01 2003-05-15 Curagen Corporation Novel proteins and nucleic acids encoding same
WO2002064781A2 (en) 2001-02-09 2002-08-22 Active Pass Pharmaceuticals, Inc. Regulation of amyloid precursor protein expression by modification of abc transporter expression or activity
US7026163B1 (en) 2001-02-23 2006-04-11 Mayo Foundation For Medical Education And Research Sulfotransferase sequence variants
IL157872A0 (en) 2001-03-12 2004-03-28 Monogen Inc A panel for detecting a generic disease state containing a plurality of probes and using cell-based diagnosis
US20030190602A1 (en) 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
AU2002250285A1 (en) 2001-03-14 2002-09-24 Medical College Of Ohio Method for quantitative measurement of gene expression for identifying individuals at risk for bronchogenic carcinoma
AU2002309583A1 (en) 2001-04-18 2002-11-05 Protein Desing Labs, Inc. Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
US6494845B2 (en) 2001-05-04 2002-12-17 Oralscan Laboratories, Inc. Retractable brush for use with endoscope for brush biopsy
US7332590B2 (en) 2001-08-16 2008-02-19 The United States Of America As Represented By The Department Of Health And Human Services Molecular characteristics of non-small cell lung cancer
CA2457527A1 (en) 2001-08-31 2003-03-13 Gen-Probe Incorporated Affinity-shifted probes for quantifying analyte polynucleotides
US6824520B2 (en) 2001-09-21 2004-11-30 Pulmonary Data Services, Inc. Method and apparatus for tracking usage of a respiratory measurement device
AU2002343443A1 (en) 2001-09-28 2003-04-14 Whitehead Institute For Biomedical Research Classification of lung carcinomas using gene expression analysis
CA2470763A1 (en) 2001-12-18 2003-06-26 Mondobiotech Laboratories Anstalt Novel pharmaceutical composition of interferon gamma or pirfenidone with molecular diagnostics for the improved treatment of interstitial lung diseases
US7141372B2 (en) 2002-01-18 2006-11-28 Health Research Incorporated Universal RT-coupled PCR method for the specific amplification of mRNA
US20040005294A1 (en) 2002-02-25 2004-01-08 Ho-Young Lee IGFBP-3 in the diagnosis and treatment of cancer
US8722331B2 (en) 2002-03-28 2014-05-13 University Of Toledo Method for selecting a treatment for non-small cell lung cancer using gene expression profiles
US20030194734A1 (en) 2002-03-29 2003-10-16 Tim Jatkoe Selection of markers
US20030186248A1 (en) 2002-03-29 2003-10-02 Erlander Mark G. Interpreting cytological specimens via molecular histological signatures
US20050143933A1 (en) 2002-04-23 2005-06-30 James Minor Analyzing and correcting biological assay data using a signal allocation model
DE10219117C1 (de) 2002-04-29 2003-10-30 Adnagen Ag Verfahren zur Stabilisierung von RNS und Verwendungen von Stabilisierungspuffern
AU2003234623A1 (en) 2002-05-16 2003-12-02 Euro-Celtique, S.A. Use of gastrin releasing peptide (grp) and its receptor in cancer screening
US20040063120A1 (en) 2002-07-10 2004-04-01 The Regents Of The University Of Michigan Expression profile of lung cancer
JP2005534686A (ja) 2002-07-31 2005-11-17 ユニバーシティ オブ サザン カリフォルニア 疾患および処置結果の予見のための多型性
AU2003272438B2 (en) 2002-09-20 2009-04-02 New England Biolabs, Inc. Helicase dependent amplification of nucleic acids
EP1403638A1 (en) 2002-09-25 2004-03-31 Mondobiotech SA Molecular methods for diagnosing interstitial lung diseases
PT2042504E (pt) 2002-09-30 2011-09-07 Bayer Schering Pharma Ag Derivados da azolepirimidina fundida
US7300788B2 (en) 2002-10-08 2007-11-27 Affymetrix, Inc. Method for genotyping polymorphisms in humans
US20050266443A1 (en) 2002-10-11 2005-12-01 Thomas Jefferson University Novel tumor suppressor gene and compositions and methods for making and using the same
ATE399882T1 (de) 2002-11-07 2008-07-15 Yoichi Matsubara Verfahren zum genmutationsnachweis
CA2513535C (en) 2003-01-29 2012-06-12 454 Corporation Bead emulsion nucleic acid amplification
WO2004070062A2 (en) 2003-02-04 2004-08-19 Wyeth Compositions and methods for diagnosing and treating cancers
CA2516553C (en) 2003-02-20 2013-04-16 Genomic Health, Inc. Use of intronic rna to measure gene expression
WO2004081564A1 (en) 2003-03-14 2004-09-23 Peter Maccallum Cancer Institute Expression profiling of tumours
US20040241725A1 (en) 2003-03-25 2004-12-02 Wenming Xiao Lung cancer detection
US20070178090A1 (en) 2003-04-01 2007-08-02 Genzyme Corporation Breast endothelial cell expression patterns
WO2004091511A2 (en) 2003-04-10 2004-10-28 Genzyme Corporation Compositions and methods to diagnose and treat lung cancer
US7378233B2 (en) 2003-04-12 2008-05-27 The Johns Hopkins University BRAF mutation T1796A in thyroid cancers
EP1633889B1 (en) 2003-05-30 2010-09-01 The Board Of Trustees Of The University Of Illinois Gene expression profiles that identify genetically elite ungulate mammals
KR20060031809A (ko) 2003-06-09 2006-04-13 더 리젠츠 오브 더 유니버시티 오브 미시간 암 치료 및 진단용 조성물 및 방법
WO2005000098A2 (en) 2003-06-10 2005-01-06 The Trustees Of Boston University Detection methods for disorders of the lung
WO2004111197A2 (en) 2003-06-10 2004-12-23 Trustees Of Boston University Gene expression signatures, methods and compositions for diagnosing disorders of the lung
EP1644858B1 (en) 2003-07-10 2017-12-06 Genomic Health, Inc. Expression profile algorithm and test for cancer prognosis
WO2005007830A2 (en) 2003-07-14 2005-01-27 Mayo Foundation For Medical Education And Research Methods and compositions for diagnosis, staging and prognosis of prostate cancer
WO2005017652A2 (en) 2003-08-05 2005-02-24 Rosetta Inpharmatics, Llc Computer systems and methods for inferring causality from cellular constituent abundance data
US7678061B2 (en) 2003-09-18 2010-03-16 Cardiac Pacemakers, Inc. System and method for characterizing patient respiration
WO2005047451A2 (en) 2003-11-12 2005-05-26 Trustees Of Boston University Isolation of nucleic acid from mouth epithelial cells
CA2549324A1 (en) 2003-12-12 2005-06-30 Bayer Pharmaceuticals Corporation Gene expression profiles and methods of use
JP2005168432A (ja) 2003-12-12 2005-06-30 Nara Institute Of Science & Technology 甲状腺濾胞癌と甲状腺濾胞腺腫を判別するためのデータを収集するための方法及び該方法のためのキット
US20050130177A1 (en) 2003-12-12 2005-06-16 3M Innovative Properties Company Variable valve apparatus and methods
WO2005062770A2 (en) 2003-12-19 2005-07-14 Novakoff James L Method for conducting pharmacogenomics-based studies
US20090020433A1 (en) 2003-12-31 2009-01-22 Microfabrica Inc. Electrochemical Fabrication Methods for Producing Multilayer Structures Including the use of Diamond Machining in the Planarization of Deposits of Material
US7407755B2 (en) 2004-01-15 2008-08-05 Lubinski Jan Determining a predisposition to cancer
CA2554818A1 (en) 2004-02-09 2005-08-25 Thomas Jefferson University Diagnosis and treatment of cancers with microrna located in or near cancer-associated chromosomal features
WO2005085471A2 (de) 2004-03-03 2005-09-15 Universität Leipzig Verfahren und mittel zur differentiellen diagnose von schilddrüsentumoren
EP1753873A4 (en) 2004-03-05 2008-11-05 Ohio Med College METHOD AND COMPOSITIONS FOR THE ASSESSMENT OF NUCLEIC ACIDS AND ALLELES
US8426126B2 (en) 2004-03-18 2013-04-23 Applied Biosystems, Llc Modified surfaces as solid supports for nucleic acid purification
WO2006028508A2 (en) 2004-03-23 2006-03-16 President And Fellows Of Harvard College Methods and apparatus for characterizing polynucleotides
JP2005304497A (ja) 2004-03-25 2005-11-04 Joji Inasawa 特定の癌関連遺伝子を用いる癌の検出方法及び癌の抑制方法
US20100075384A1 (en) 2004-03-25 2010-03-25 New England Biolabs, Inc. Helicase-dependent amplification of circular nucleic acids
US7319011B2 (en) 2004-04-08 2008-01-15 Duke University Method for distinguishing follicular thyroid adenoma (FTA) from follicular thyroid carcinoma (FTC)
ATE491043T1 (de) 2004-04-09 2010-12-15 Us Gov Health & Human Serv Diagnosegerät zur diagnose gutartiger gegenüber bösartigen schilddrüsenläsionen
US20050240357A1 (en) 2004-04-26 2005-10-27 Minor James M Methods and systems for differential clustering
US20060019272A1 (en) 2004-05-03 2006-01-26 The Regents Of The University Of Colorado Diagnosis of disease and monitoring of therapy using gene expression analysis of peripheral blood cells
EP2290071B1 (en) 2004-05-28 2014-12-31 Asuragen, Inc. Methods and compositions involving microRNA
US20060088851A1 (en) 2004-06-04 2006-04-27 Arcturus Bioscience, Inc. Invasion/migration gene
JP4533015B2 (ja) 2004-06-15 2010-08-25 キヤノン株式会社 化合物及びそれを用いた有機エレクトロルミネッセンス素子
US20060019615A1 (en) 2004-07-24 2006-01-26 Ditmer Larry R Wireless keying for a continuous wave (CW) amateur radio transmitter
GB0417740D0 (en) 2004-08-10 2004-09-08 Uc3 Methods and kit for the prognosis of breast cancer
EP1778872A2 (en) * 2004-08-11 2007-05-02 The Cleveland Clinic Foundation Method of detecting thyroid cancer
EP1784754A4 (en) 2004-08-13 2009-05-27 Harvard College OPTI-NANOPORE DNA READING PLATFORM WITH ULTRAHOLE THROUGHPUT
AT414115B (de) 2004-09-17 2006-09-15 Knorr Bremse Gmbh Bodenverriegelung
PT3428191T (pt) 2004-10-06 2024-12-30 Mayo Found Medical Education & Res B7-h1 e tratamento do carcinona de células renais
US7629325B2 (en) 2004-10-11 2009-12-08 Technion Research & Development Foundation Ltd. Human Sef isoforms and methods of using same for cancer diagnosis and gene therapy
US7485468B2 (en) 2004-10-15 2009-02-03 Galapagos Bv Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
WO2006047481A2 (en) 2004-10-22 2006-05-04 Redpath Integrated Pathology, Inc. Enhanced amplifiability of minute fixative-treated tissue samples, minute stained cytology samples, and other minute sources of dna
BRPI0518734A2 (pt) 2004-11-30 2008-12-02 Veridex Llc prognàstico de cÂncer de pulmço
ES2356830T3 (es) 2004-12-03 2011-04-13 Schering Corporation Biomarcadores para preselección de pacientes para terapia de anti-igf-1r.
JP5629894B2 (ja) 2004-12-07 2014-11-26 国立大学法人大阪大学 甲状腺乳頭癌を診断するための新規のマーカー
US7862995B2 (en) 2004-12-10 2011-01-04 Targeted Molecular Diagnostics Methods and materials for predicting responsiveness to treatment with dual tyrosine kinase inhibitor
EP1851334A4 (en) 2005-01-21 2010-05-26 Gene Express Inc DATABASES FOR EVALUATING NUCLEIC ACIDS
US20120122718A1 (en) 2005-03-01 2012-05-17 Reisman David N BRM Expression and Related Diagnostics
WO2006105252A2 (en) 2005-03-28 2006-10-05 The Regents Of The University Of Colorado Diagnosis of chronic pulmonary obstructive disease and monitoring of therapy using gene expression analysis of peripheral blood cells
WO2006110593A2 (en) 2005-04-07 2006-10-19 Macrogenics, Inc. Biological targets for the diagnosis, treatment and prevention of cancer
EP1874962A2 (en) 2005-04-14 2008-01-09 The Trustees Of Boston University Diagnostic for lung disorders using class prediction
US20200248274A1 (en) 2005-04-14 2020-08-06 Trustees Of Boston University Diagnostic for lung disorders using class prediction
US20070020657A1 (en) 2005-05-20 2007-01-25 Grebe Stefan K Methods for detecting circulating tumor cells
US20070037186A1 (en) 2005-05-20 2007-02-15 Yuqiu Jiang Thyroid fine needle aspiration molecular assay
DK1899484T3 (da) 2005-06-03 2015-11-23 Biotheranostics Inc Identifikation af tumorer og væv
WO2006138275A2 (en) 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20070099209A1 (en) 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
IL177006A0 (en) 2005-08-02 2006-12-10 Veridex Llc Predicting bone relapse of breast cancer
ZA200800970B (en) 2005-08-15 2009-10-28 Genentech Inc Gene disruptions, compositions and methods relating thereto
EP1940860B1 (en) 2005-09-02 2012-08-08 The University of Toledo Methods for identifying biomarkers useful in diagnosis and/or treatment of biological states
JP2009516501A (ja) 2005-09-22 2009-04-23 チャイナ シンセティック ラバー コーポレーション 鼻咽腔癌の予後的サブクラスの同定のための遺伝子発現プロファイリング
CA2624086A1 (en) 2005-09-28 2007-04-05 H. Lee Moffitt Cancer Center Individualized cancer treatments
US7962291B2 (en) 2005-09-30 2011-06-14 Affymetrix, Inc. Methods and computer software for detecting splice variants
EP1943356B1 (en) 2005-10-03 2014-05-14 Epigenomics AG Methods and nucleic acids for the analysis of gene expression associated with the prognosis of cell proliferative disorders
US7598052B2 (en) 2005-10-11 2009-10-06 The Regents Of The University Of Michigan Expression profile of thyroid cancer
US20070220621A1 (en) 2005-10-31 2007-09-20 Clarke Michael F Genetic characterization and prognostic significance of cancer stem cells in cancer
US9347945B2 (en) 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
FR2896881B1 (fr) 2006-01-31 2008-04-18 Biomerieux Sa Procede de dosage du prongf pour le diagnostic in vitro du cancer du sein et utilisation du prongf en therapie
US7670775B2 (en) * 2006-02-15 2010-03-02 The Ohio State University Research Foundation Method for differentiating malignant from benign thyroid tissue
EP2605018A1 (en) 2006-03-09 2013-06-19 The Trustees of the Boston University Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
JP4867018B2 (ja) 2006-03-22 2012-02-01 富士フイルム株式会社 癌の検出方法および抑制方法
WO2007126882A2 (en) 2006-03-27 2007-11-08 Jivan Biologics, Inc. Analysis of splice variant expression data
US20080028302A1 (en) 2006-07-31 2008-01-31 Steffen Meschkat Method and apparatus for incrementally updating a web page
KR20080020083A (ko) 2006-08-30 2008-03-05 유영도 암 진단 마커로서의 Romo1의 용도
KR101443214B1 (ko) 2007-01-09 2014-09-24 삼성전자주식회사 폐암 환자 또는 폐암 치료를 받은 폐암 환자의 폐암 재발 위험을 진단하기 위한 조성물, 키트 및 마이크로어레이
HUE028487T2 (en) 2007-02-27 2016-12-28 Sentoclone Int Ab Detection of tumor cell multiplex using panel of agents associated with extracellular markers
US20100119474A1 (en) 2007-03-06 2010-05-13 Cornell University Chronic obstructive pulmonary disease susceptibility and related compositions and methods
CA2678919A1 (en) 2007-03-27 2008-10-02 Ranit Aharonov Gene expression signature for classification of cancers
US20100273172A1 (en) 2007-03-27 2010-10-28 Rosetta Genomics Ltd. Micrornas expression signature for determination of tumors origin
US8802599B2 (en) 2007-03-27 2014-08-12 Rosetta Genomics, Ltd. Gene expression signature for classification of tissue of origin of tumor samples
WO2010073248A2 (en) 2008-12-24 2010-07-01 Rosetta Genomics Ltd. Gene expression signature for classification of tissue of origin of tumor samples
US9096906B2 (en) 2007-03-27 2015-08-04 Rosetta Genomics Ltd. Gene expression signature for classification of tissue of origin of tumor samples
EP1975245A1 (de) 2007-03-28 2008-10-01 Greenpeace e.V. Gen-Profiling zur Auswahl von politischen Kandidaten, kommerzielle Nutzung von Politikern
EP1975252A1 (en) 2007-03-29 2008-10-01 INSERM (Institut National de la Santé et de la Recherche Medicale) Methods for the prognosis or for the diagnosis of a thyroid disease
US8455208B2 (en) 2007-04-14 2013-06-04 The Regents Of The University Of Colorado Biomarkers for follicular thyroid carcinoma and methods of use
WO2008140774A2 (en) 2007-05-08 2008-11-20 Picobella Llc Methods for diagnosing and treating prostate and lung cancer
US7901888B2 (en) 2007-05-09 2011-03-08 The Regents Of The University Of California Multigene diagnostic assay for malignant thyroid neoplasm
CA2690898A1 (en) 2007-06-08 2008-12-18 Biogen Idec Ma Inc. Biomarkers for predicting anti-tnf responsiveness or non-responsiveness
AU2008283997B2 (en) 2007-08-03 2014-04-10 The Ohio State University Research Foundation Ultraconserved regions encoding ncRNAs
US9234244B2 (en) 2007-08-27 2016-01-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Diagnostic tool for diagnosing benign versus malignant thyroid lesions
AT505726A2 (de) 2007-08-30 2009-03-15 Arc Austrian Res Centers Gmbh Set von tumor-markern
RU2511408C2 (ru) 2007-09-17 2014-04-10 Конинклейке Филипс Электроникс Н.В. Способ анализа нарушений, связанных с раком яичников
CN101990577A (zh) 2007-09-19 2011-03-23 波士顿大学理事会 鉴定肺病药物开发的新途径
WO2009037337A1 (en) 2007-09-20 2009-03-26 Novartis Ag Robust and tissue independent gender-specific transcript markers for molecular gender determination
US20100285468A1 (en) * 2007-09-24 2010-11-11 Allelogic Biosciences Corporation Detection and/or quantification of nucleic acids
US20100255485A1 (en) 2007-11-28 2010-10-07 Pico Caroni Biomarkers for the onset of neurodegenerative diseases
US8476420B2 (en) 2007-12-05 2013-07-02 The Wistar Institute Of Anatomy And Biology Method for diagnosing lung cancers using gene expression profiles in peripheral blood mononuclear cells
CN101918591A (zh) 2007-12-14 2010-12-15 维里德克斯有限责任公司 能预测人类乳腺癌转移能力的拷贝数变化
US20090191535A1 (en) 2007-12-22 2009-07-30 Mark Carle Connelly Method of assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells
AU2009203785A1 (en) 2008-01-04 2009-07-16 Centre National De La Recherche Scientifique Molecular in vitro diagnosis of breast cancer
KR20100120657A (ko) 2008-01-22 2010-11-16 베리덱스, 엘엘씨 Ⅱ기 및 ⅲ기 결장암의 분자적 병기 및 예후
GB2469244A (en) 2008-01-28 2010-10-06 Univ Singapore Lipid tumour profile
US20090246779A1 (en) 2008-02-15 2009-10-01 University Of Washington Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array-cgh
WO2009111881A1 (en) 2008-03-13 2009-09-17 British Columbia Cancer Agency Branch Biomarkers for diagnosis of differentiated thyroid cancer
WO2009120800A2 (en) 2008-03-25 2009-10-01 University Of Southern California Prognostic panel for urinary bladder cancer
WO2009121070A1 (en) 2008-03-28 2009-10-01 The Trustees Of Boston University Multifactorial methods for detecting lung disorders
WO2009126271A1 (en) 2008-04-11 2009-10-15 China Synthetic Rubber Corporation Methods, agents and kits for the detection of cancer
JP2011523049A (ja) 2008-05-14 2011-08-04 ドナー, インコーポレイテッド 頭頚部癌の同定、モニタリングおよび治療のためのバイオマーカー
EP2806054A1 (en) 2008-05-28 2014-11-26 Genomedx Biosciences Inc. Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
CA2726531A1 (en) 2008-06-05 2009-12-10 University Health Network Compositions and methods for classifying lung cancer and prognosing lung cancer survival
WO2009148184A1 (ja) 2008-06-05 2009-12-10 国立大学法人佐賀大学 特発性間質性肺炎の検出方法
US20110077168A1 (en) 2008-06-17 2011-03-31 Nitzan Rosenfeld Methods for distinguishing between specific types of lung cancers
GB0811413D0 (en) 2008-06-20 2008-07-30 Kanton Basel Stadt Gene expression signatures for lung cancers
ES2338843B1 (es) 2008-07-02 2011-01-24 Centro De Investigaciones Energeticas, Medioambientales Y Tecnologicas Huella genomica de cancer de mama.
CA2729931A1 (en) 2008-07-07 2010-01-14 Decode Genetics Ehf Genetic variants predictive of cancer risk in humans
WO2010008543A2 (en) 2008-07-15 2010-01-21 Trustees Of Dartmouth College Molecular signatures for diagnosing scleroderma
US20110230366A1 (en) 2008-08-12 2011-09-22 Decode Genetics Ehf. Genetic Variants Useful for Risk Assessment of Thyroid Cancer
US20110212855A1 (en) 2008-08-15 2011-09-01 Decode Genetics Ehf. Genetic Variants Predictive of Cancer Risk
EP2326734B1 (en) 2008-09-03 2016-11-09 The Johns Hopkins University Pathways underlying pancreatic tumorigenesis and an hereditary pancreatic cancer gene
WO2010028274A1 (en) 2008-09-05 2010-03-11 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Marker panels for idiopathic pulmonary fibrosis diagnosis and evaluation
US20110251091A1 (en) 2008-09-12 2011-10-13 Cornell University Thyroid tumors identified
EP3075864A1 (en) 2008-10-14 2016-10-05 Caris MPI, Inc. Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type
WO2010054233A1 (en) 2008-11-08 2010-05-14 The Wistar Institute Of Anatomy And Biology Biomarkers in peripheral blood mononuclear cells for diagnosing or detecting lung cancers
CA2742489A1 (en) 2008-11-14 2010-05-20 Intelligent Oncotherapeutics, Inc. Methods for identification of tumor phenotype and treatment
US20110230372A1 (en) 2008-11-14 2011-09-22 Stc Unm Gene expression classifiers for relapse free survival and minimal residual disease improve risk classification and outcome prediction in pediatric b-precursor acute lymphoblastic leukemia
GB2512153B (en) 2008-11-17 2014-11-12 Veracyte Inc Methods and compositions of molecular profiling for disease diagnostics
US9495515B1 (en) 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
WO2010060031A1 (en) 2008-11-21 2010-05-27 Anthrogenesis Corporation Treatment of diseases, disorders or conditions of the lung using placental cells
EP2385989A4 (en) 2008-11-26 2012-04-25 Decode Genetics Ehf GENETIC VARIANTS FOR THE RISK ASSESSMENT OF THYROID CANCER
US9090943B2 (en) 2008-11-30 2015-07-28 Rosetta Genomics Ltd. Methods for detecting an increased susceptibility to cancer
BRPI1004572A2 (pt) 2009-01-09 2016-04-05 Univ Michigan "fusões genéticas recorrentes em câncer
US20100204058A1 (en) 2009-01-28 2010-08-12 Howard Yuan-Hao Chang Profiling for Determination of Response to Treatment for Inflammatory Disease
WO2010091049A2 (en) 2009-02-03 2010-08-12 Children's Medical Center Corporation Diagnosis and treatment of cancer
US8697275B2 (en) 2009-03-04 2014-04-15 Samsung Sdi Co., Ltd. Rechargeable battery having an extendable case region
US9074258B2 (en) 2009-03-04 2015-07-07 Genomedx Biosciences Inc. Compositions and methods for classifying thyroid nodule disease
WO2010123626A1 (en) 2009-04-24 2010-10-28 University Of Southern California Cd133 polymorphisms and expression predict clinical outcome in patients with cancer
WO2010124372A1 (en) 2009-04-29 2010-11-04 Genomedx Biosciences, Inc. Systems and methods for expression-based classification of thyroid tissue
WO2010127322A1 (en) 2009-05-01 2010-11-04 Genomic Health Inc. Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy
JP6078339B2 (ja) 2009-05-07 2017-02-08 ベラサイト インコーポレイテッド 甲状腺状態の診断のための方法および組成物
EP2427574A2 (en) 2009-05-08 2012-03-14 The Ohio State University Research Foundation Microrna expression profiling and targeting in chronic obstructive pulmonary disease (copd) lung tissue and methods of use thereof
US8735074B2 (en) 2009-08-28 2014-05-27 Asuragen, Inc. MiRNA biomarkers of lung disease
JP2013502906A (ja) 2009-08-31 2013-01-31 アルケド バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング 染色体再編成を伴う腫瘍の診断、予後及び治療のためのマイクロrnaに基づいた方法及び組成物
US9110065B2 (en) 2009-09-21 2015-08-18 Paul Walfish Methods and compositions for the diagnosis and treatment of thyroid cancer
AU2010302955A1 (en) 2009-10-01 2012-05-17 Chipdx Llc System and method for classification of patients
US20120329666A1 (en) 2009-10-05 2012-12-27 Duke University Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia and Methods of Use
CA2777800C (en) 2009-10-15 2019-11-12 Crescendo Bioscience Biomarkers and methods for measuring and monitoring inflammatory disease activity
US8975019B2 (en) 2009-10-19 2015-03-10 University Of Massachusetts Deducing exon connectivity by RNA-templated DNA ligation/sequencing
CN102640001A (zh) 2009-11-05 2012-08-15 诺瓦提斯公司 预测纤维化进展的生物标记物
US10446272B2 (en) 2009-12-09 2019-10-15 Veracyte, Inc. Methods and compositions for classification of samples
US20130231258A1 (en) 2011-12-09 2013-09-05 Veracyte, Inc. Methods and Compositions for Classification of Samples
WO2011079846A2 (en) 2009-12-30 2011-07-07 Rigshospitalet Mrna classification of thyroid follicular neoplasia
GB201000688D0 (en) 2010-01-15 2010-03-03 Diagenic Asa Product and method
DK2529033T3 (en) 2010-01-26 2017-08-07 Nat Jewish Health PROCEDURES FOR PREVENTING THE RISK OF, DIAGNOSTICATION AND PROJECTING OF LUNG DISEASES
EP2366800A1 (en) 2010-03-01 2011-09-21 Centrum Onkologii-Instytut im M. Sklodowskiej-Curie Oddzial w Gliwicach Kit, method and use for the diagnosis of papillary thyroid cancer using a gene expression profile
WO2011116380A2 (en) 2010-03-19 2011-09-22 H. Lee Moffitt Cancer Center And Research Institute, Inc. Hybrid model for the classification of carcinoma subtypes
US20130029873A1 (en) 2010-04-12 2013-01-31 University Health Network Methods and compositions for diagnosing pulmonary fibrosis subtypes and assessing the risk of primary graft dysfunction after lung transplantation
US9157123B2 (en) 2010-04-20 2015-10-13 The Johns Hopkins University Genetic amplification of IQGAP1 in cancer
US20110269142A1 (en) 2010-04-30 2011-11-03 President And Fellows Of Harvard College Clinical Method for Individualized Epithelial Cancer Screening Involving ERCC5 and IGF2R Genetic Testing and Gene-Environment Interactions
US20190100809A1 (en) 2010-05-11 2019-04-04 Veracyte, Inc. Algorithms for disease diagnostics
US20110312520A1 (en) 2010-05-11 2011-12-22 Veracyte, Inc. Methods and compositions for diagnosing conditions
MX355020B (es) 2010-07-09 2018-04-02 Somalogic Inc Biomarcadores de cancer de pulmon y usos de los mismos.
US20130295571A1 (en) 2010-10-29 2013-11-07 Institut National De La Santee Et De La Recherche Medicale ( Inserm) Marker of breast tumors from the luminal-b subtype
JP6155194B2 (ja) 2010-11-17 2017-06-28 インターペース ダイアグノスティックス リミテッド ライアビリティ カンパニー 良性甲状腺新生物と悪性甲状腺新生物を区別するためのバイオマーカーとしてのmiRNA
US20130273543A1 (en) 2010-12-21 2013-10-17 Decode Genetics Ehf. Genetic variants useful for risk assessment of thyroid cancer
KR20190002733A (ko) 2010-12-30 2019-01-08 파운데이션 메디신 인코포레이티드 종양 샘플의 다유전자 분석의 최적화
US20130303826A1 (en) 2011-01-11 2013-11-14 University Health Network Prognostic signature for oral squamous cell carcinoma
US20140087961A1 (en) 2011-03-17 2014-03-27 Illumina Inc. Genetic variants useful for risk assessment of thyroid cancer
US9585930B2 (en) 2011-03-20 2017-03-07 Trustees Of Boston University Therapeutic agent for emphysema and COPD
US8945829B2 (en) 2011-03-22 2015-02-03 Cornell University Distinguishing benign and malignant indeterminate thyroid lesions
EP2505664B1 (en) 2011-03-30 2014-12-03 Universität Leipzig Method and means for distinguishing malignant from benign tumor samples, in particular in routine air dried fine needle aspiration biopsy (FNAB)
AU2012249288C1 (en) 2011-04-29 2017-12-21 Lung Cancer Proteomics Llc Methods of identification and diagnosis of lung diseases using classification systems and kits thereof
US20120288860A1 (en) 2011-05-12 2012-11-15 George Mason University Differential gene expression for detecting and/or differentiating lung disease
ITPD20110201A1 (it) 2011-06-16 2012-12-17 Univ Degli Studi Trieste Metodo per la prognosi di tumori al seno basata sull'espressione dell'enzima prolil isomerarasi pin1 in combinazione con mutazioni del gene tp53
US20140302042A1 (en) 2011-07-01 2014-10-09 Dana-Farber Cancer Institute, Inc. Methods of predicting prognosis in cancer
KR20130017525A (ko) 2011-08-11 2013-02-20 주식회사 젠닥스 대장암, 유방암, 신장암 또는 갑상선암의 조기 진단을 위한 바이오 마커 및 이의 용도
WO2013033640A1 (en) 2011-09-01 2013-03-07 Allegro Diagnostics Corp. Methods and compositions for detecting cancer based on mirna expression profiles
WO2013049152A2 (en) 2011-09-26 2013-04-04 Allegro Diagnostics Corp. Methods for evaluating lung cancer status
WO2013066678A1 (en) 2011-10-26 2013-05-10 Georgetown University Microrna expression profiling of thyroid cancer
EP2771487A1 (en) 2011-10-27 2014-09-03 Asuragen, INC. Mirnas as diagnostic biomarkers to distinguish benign from malignant thyroid tumors
WO2013083687A1 (en) 2011-12-09 2013-06-13 Pronota N.V. Ltbp2 as a biomarker for lung injury
WO2013086524A1 (en) 2011-12-09 2013-06-13 The Johns Hopkins University Compositions and methods for characterizing thyroid neoplasia
WO2013086522A1 (en) 2011-12-10 2013-06-13 Veracyte, Inc. Methods and compositions for sample identification
WO2013088457A1 (en) 2011-12-13 2013-06-20 Decode Genetics Ehf Genetic variants useful for risk assessment of thyroid cancer
US9753043B2 (en) 2011-12-18 2017-09-05 20/20 Genesystems, Inc. Methods and algorithms for aiding in the detection of cancer
US20130184999A1 (en) 2012-01-05 2013-07-18 Yan Ding Systems and methods for cancer-specific drug targets and biomarkers discovery
WO2013134786A2 (en) 2012-03-09 2013-09-12 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Biomarker compositions and methods
US20150038376A1 (en) 2012-03-15 2015-02-05 Qiagen Sciences Llc Thyroid cancer biomarker
MX370486B (es) 2012-03-27 2019-12-16 Genentech Inc Composiciones, métodos y usos para asistir en el diagnóstico, pronóstico y tratamiento de la fibrosis pulmonar idiopática.
JP2013212052A (ja) 2012-03-30 2013-10-17 Yale Univ Krasバリアントおよび腫瘍生物学
DE18200782T1 (de) 2012-04-02 2021-10-21 Modernatx, Inc. Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen
WO2013163568A2 (en) 2012-04-26 2013-10-31 Allegro Diagnostics Corp. Methods for evaluating lung cancer status
US20150141470A1 (en) 2012-05-08 2015-05-21 The Broad Institute, Inc. Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy
WO2013177060A2 (en) 2012-05-20 2013-11-28 Trustees Of Boston University Methods and systems for monitoring, diagnosing, and treating chronic obstructive polmonary disease
BR112014030569B1 (pt) 2012-06-08 2021-12-28 Koninklijke Philips N.V Método de monitoramento da função pulmonar de um paciente usando um sistema que tem um aparelho respiratório e uma unidade de processamento, e sistema para uso no monitoramento da função pulmonar de um paciente
WO2013190092A1 (en) 2012-06-21 2013-12-27 Philip Morris Products S.A. Gene signatures for copd diagnosis
US10047401B2 (en) 2012-08-20 2018-08-14 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Expression protein-coding and noncoding genes as prognostic classifiers in early stage lung cancer
CA2885202A1 (en) 2012-09-20 2014-03-27 Genomedx Biosciences, Inc. Thyroid cancer diagnostics
WO2014058317A1 (en) 2012-10-10 2014-04-17 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Methods and means for predicting resistance to anti-cancer treatment
BR102013027577A2 (pt) 2012-10-25 2016-03-29 Memorialsloan Kettering Cancer Ct método de detecção de um nível aumentado de axl ou gas6 e método de identificação de um paciente com câncer resistente a inibidor de egfr
US20140143188A1 (en) 2012-11-16 2014-05-22 Genformatic, Llc Method of machine learning, employing bayesian latent class inference: combining multiple genomic feature detection algorithms to produce an integrated genomic feature set with specificity, sensitivity and accuracy
EP2925886B1 (en) 2012-11-27 2019-04-24 Pontificia Universidad Católica de Chile Compositions and methods for diagnosing thyroid tumors
EP2929350A4 (en) 2012-12-04 2016-11-16 Caris Mpi Inc MOLECULAR PROFILING OF CANCER
KR102216949B1 (ko) 2012-12-14 2021-02-22 민데라 코포레이션 바이오마커의 검출 및 취득을 위한 방법 및 디바이스
US20140220006A1 (en) 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Lung cancer biomarkers
CA2902871A1 (en) 2013-03-12 2014-10-09 Cepheid Methods of detecting cancer
US10526655B2 (en) 2013-03-14 2020-01-07 Veracyte, Inc. Methods for evaluating COPD status
EP2971128B1 (en) 2013-03-15 2023-03-01 Veracyte, Inc. Biomarkers for diagnosis of lung diseases and methods of use thereof
AU2014229505B2 (en) 2013-03-15 2020-02-27 Fundacio Institut De Recerca Biomedica (Irb Barcelona) Method for the prognosis and treatment of cancer metastasis
CA2901384A1 (en) 2013-03-15 2014-09-18 Intermune, Inc. Proteomic ipf markers
US20140349856A1 (en) 2013-03-15 2014-11-27 Biotheranostics, Inc. Neuroendocrine Tumors
WO2014151764A2 (en) 2013-03-15 2014-09-25 Veracyte, Inc. Methods and compositions for classification of samples
EP2986736B1 (en) 2013-04-17 2019-09-18 Life Technologies Corporation Gene fusions and gene variants associated with cancer
EP2993980B1 (en) 2013-05-10 2023-11-01 Memorial Sloan Kettering Cancer Center Lipid scavenging in ras cancers
RU2677742C2 (ru) 2013-11-07 2019-01-21 Медиал Рисеч Лтд. Способы и системы оценки риска развития злокачественной опухоли легкого
PL406033A1 (pl) 2013-11-14 2015-05-25 Warszawski Uniwersytet Medyczny Sposób diagnozowania raka brodawkowatego tarczycy, zastosowanie markera mikroRNA do diagnozowania nowotworu tarczycy, oceny stopnia zaawansowania choroby oraz oceny podatności pacjenta i/lub choroby na zaproponowane leczenie oraz zawierający takie markery zestaw diagnostyczny
US9708667B2 (en) 2014-05-13 2017-07-18 Rosetta Genomics, Ltd. MiRNA expression signature in the classification of thyroid tumors
WO2016011068A1 (en) 2014-07-14 2016-01-21 Allegro Diagnostics Corp. Methods for evaluating lung cancer status
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
EP3770274A1 (en) 2014-11-05 2021-01-27 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
WO2016094330A2 (en) 2014-12-08 2016-06-16 20/20 Genesystems, Inc Methods and machine learning systems for predicting the liklihood or risk of having cancer
CN114634985A (zh) 2015-03-04 2022-06-17 威拉赛特公司 使用表达水平和序列变体信息评估疾病发生或复发风险的方法
US20170127976A1 (en) 2015-06-11 2017-05-11 Michael Phillips Method and apparatus for identification of biomarkers in breath and methods of usng same for prediction of lung cancer
WO2017065959A2 (en) 2015-09-25 2017-04-20 Veracyte, Inc. Methods and compositions that utilize transcriptome sequencing data in machine learning-based classification
US20190292600A1 (en) 2016-05-12 2019-09-26 Trustees Of Boston University Nasal epithelium gene expression signature and classifier for the prediction of lung cancer
US10927417B2 (en) 2016-07-08 2021-02-23 Trustees Of Boston University Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions
AU2017324949B2 (en) 2016-09-07 2024-05-23 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
CN110958853B (zh) 2017-06-02 2023-08-25 威拉赛特公司 用于鉴定或监测肺病的方法和系统
US11217329B1 (en) 2017-06-23 2022-01-04 Veracyte, Inc. Methods and systems for determining biological sample integrity
WO2019023517A2 (en) 2017-07-27 2019-01-31 Veracyte, Inc. GENOMIC SEQUENCING CLASSIFIER

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