JP2012511928A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012511928A5 JP2012511928A5 JP2011542150A JP2011542150A JP2012511928A5 JP 2012511928 A5 JP2012511928 A5 JP 2012511928A5 JP 2011542150 A JP2011542150 A JP 2011542150A JP 2011542150 A JP2011542150 A JP 2011542150A JP 2012511928 A5 JP2012511928 A5 JP 2012511928A5
- Authority
- JP
- Japan
- Prior art keywords
- moth
- encoded
- group
- coa
- gene selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 66
- 108090000623 proteins and genes Proteins 0.000 claims 66
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 claims 36
- 229910002091 carbon monoxide Inorganic materials 0.000 claims 30
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 26
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 claims 26
- 230000037361 pathway Effects 0.000 claims 23
- 102100025413 Formyltetrahydrofolate synthetase Human genes 0.000 claims 21
- 102000004190 Enzymes Human genes 0.000 claims 20
- 108090000790 Enzymes Proteins 0.000 claims 20
- 230000015572 biosynthetic process Effects 0.000 claims 18
- 244000005700 microbiome Species 0.000 claims 18
- 108010010685 Methenyltetrahydrofolate cyclohydrolase Proteins 0.000 claims 14
- 102000055027 Protein Methyltransferases Human genes 0.000 claims 14
- 108700040121 Protein Methyltransferases Proteins 0.000 claims 14
- 229920001184 polypeptide Polymers 0.000 claims 14
- 102000004196 processed proteins & peptides Human genes 0.000 claims 14
- 108090000765 processed proteins & peptides Proteins 0.000 claims 14
- 238000003786 synthesis reaction Methods 0.000 claims 12
- TZBGSHAFWLGWBO-ABLWVSNPSA-N (2s)-2-[[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1h-pteridin-6-yl)methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid Chemical compound C1=CC(C(=O)N[C@@H](CCC(=O)OC)C(O)=O)=CC=C1NCC1NC(C(=O)NC(N)=N2)=C2NC1 TZBGSHAFWLGWBO-ABLWVSNPSA-N 0.000 claims 10
- -1 thlB Proteins 0.000 claims 10
- 108010006229 Acetyl-CoA C-acetyltransferase Proteins 0.000 claims 8
- 102100037768 Acetyl-CoA acetyltransferase, mitochondrial Human genes 0.000 claims 8
- 108010074122 Ferredoxins Proteins 0.000 claims 8
- 108090000698 Formate Dehydrogenases Proteins 0.000 claims 7
- 108010080982 Formate-tetrahydrofolate ligase Proteins 0.000 claims 7
- 108010020056 Hydrogenase Proteins 0.000 claims 7
- 108010081409 Iron-Sulfur Proteins Proteins 0.000 claims 7
- 102000005298 Iron-Sulfur Proteins Human genes 0.000 claims 7
- 101710159527 Maturation protein A Proteins 0.000 claims 7
- 101710091157 Maturation protein A2 Proteins 0.000 claims 7
- 102000005954 Methylenetetrahydrofolate Reductase (NADPH2) Human genes 0.000 claims 7
- 108010030837 Methylenetetrahydrofolate Reductase (NADPH2) Proteins 0.000 claims 7
- 102000004316 Oxidoreductases Human genes 0.000 claims 7
- 108090000854 Oxidoreductases Proteins 0.000 claims 7
- 108010031234 carbon monoxide dehydrogenase Proteins 0.000 claims 7
- 230000000694 effects Effects 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- SJZRECIVHVDYJC-UHFFFAOYSA-M 4-hydroxybutyrate Chemical compound OCCCC([O-])=O SJZRECIVHVDYJC-UHFFFAOYSA-M 0.000 claims 6
- 101100215658 Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) aflY gene Proteins 0.000 claims 6
- 101100232322 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) hypA2 gene Proteins 0.000 claims 6
- 101710088194 Dehydrogenase Proteins 0.000 claims 6
- 101100227555 Moorella thermoacetica (strain ATCC 39073 / JCM 9320) folD gene Proteins 0.000 claims 6
- 108010031852 Pyruvate Synthase Proteins 0.000 claims 6
- 101100232321 Synechocystis sp. (strain PCC 6803 / Kazusa) hypA1 gene Proteins 0.000 claims 6
- 101150081706 acsAB gene Proteins 0.000 claims 6
- 101150006844 groES gene Proteins 0.000 claims 6
- 101150081485 hypA gene Proteins 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 239000002994 raw material Substances 0.000 claims 6
- 108010055682 3-hydroxybutyryl-CoA dehydrogenase Proteins 0.000 claims 5
- BAMBWCGEVIAQBF-CITAKDKDSA-N 4-hydroxybutyryl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCCO)O[C@H]1N1C2=NC=NC(N)=C2N=C1 BAMBWCGEVIAQBF-CITAKDKDSA-N 0.000 claims 5
- 101710168556 Chromodomain Y-like protein Proteins 0.000 claims 5
- 102100031668 Chromodomain Y-like protein Human genes 0.000 claims 5
- 101710188748 Crotonyl-CoA hydratase Proteins 0.000 claims 5
- 108010023922 Enoyl-CoA hydratase Proteins 0.000 claims 5
- 102000011426 Enoyl-CoA hydratase Human genes 0.000 claims 5
- 102100039894 Hemoglobin subunit delta Human genes 0.000 claims 5
- 101100297400 Rhizobium meliloti (strain 1021) phaAB gene Proteins 0.000 claims 4
- 102000004357 Transferases Human genes 0.000 claims 4
- 108090000992 Transferases Proteins 0.000 claims 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- 101100396130 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) hypD1 gene Proteins 0.000 claims 3
- 101100018292 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) hypD2 gene Proteins 0.000 claims 3
- 101100059802 Chlamydophila caviae (strain ATCC VR-813 / DSM 19441 / GPIC) groEL1 gene Proteins 0.000 claims 3
- 101100365080 Clostridium perfringens (strain 13 / Type A) scpB gene Proteins 0.000 claims 3
- 101100018311 Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) hypF1 gene Proteins 0.000 claims 3
- 101100507971 Escherichia coli (strain K12) hycC gene Proteins 0.000 claims 3
- 101100507972 Escherichia coli (strain K12) hycD gene Proteins 0.000 claims 3
- 101100507973 Escherichia coli (strain K12) hycE gene Proteins 0.000 claims 3
- 101100507974 Escherichia coli (strain K12) hycF gene Proteins 0.000 claims 3
- 101100507975 Escherichia coli (strain K12) hycG gene Proteins 0.000 claims 3
- 101100071894 Escherichia coli (strain K12) hyfB gene Proteins 0.000 claims 3
- 101100071895 Escherichia coli (strain K12) hyfC gene Proteins 0.000 claims 3
- 101100071896 Escherichia coli (strain K12) hyfD gene Proteins 0.000 claims 3
- 101100071902 Escherichia coli (strain K12) hyfG gene Proteins 0.000 claims 3
- 101100071903 Escherichia coli (strain K12) hyfH gene Proteins 0.000 claims 3
- 101100071904 Escherichia coli (strain K12) hyfI gene Proteins 0.000 claims 3
- 101100071905 Escherichia coli (strain K12) hyfJ gene Proteins 0.000 claims 3
- 101100071906 Escherichia coli (strain K12) hyfR gene Proteins 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- 101100111747 Eupenicillium brefeldianum Bref-PKS gene Proteins 0.000 claims 3
- 101000716763 Homo sapiens Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial Proteins 0.000 claims 3
- 101100458377 Methanosarcina barkeri (strain Fusaro / DSM 804) mtaC gene Proteins 0.000 claims 3
- 101100071901 Methylacidiphilum infernorum (isolate V4) hyfF gene Proteins 0.000 claims 3
- 102000016397 Methyltransferase Human genes 0.000 claims 3
- 108060004795 Methyltransferase Proteins 0.000 claims 3
- 101100013513 Moorella thermoacetica (strain ATCC 39073 / JCM 9320) fhs gene Proteins 0.000 claims 3
- 101100071908 Moorella thermoacetica (strain ATCC 39073 / JCM 9320) hypA gene Proteins 0.000 claims 3
- 101100269045 Moorella thermoacetica acsE gene Proteins 0.000 claims 3
- 101100445407 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) erg10B gene Proteins 0.000 claims 3
- 101100226895 Phomopsis amygdali PaP450-3 gene Proteins 0.000 claims 3
- 101100000272 Rhizobium meliloti (strain 1021) acsA2 gene Proteins 0.000 claims 3
- 101100440643 Rhodospirillum rubrum cooC gene Proteins 0.000 claims 3
- 102100020868 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial Human genes 0.000 claims 3
- 108091022873 acetoacetate decarboxylase Proteins 0.000 claims 3
- 101150116076 acsA gene Proteins 0.000 claims 3
- 101150083305 acsA2 gene Proteins 0.000 claims 3
- 101150095811 acsC gene Proteins 0.000 claims 3
- 101150040108 acsD gene Proteins 0.000 claims 3
- 101150006429 atoB gene Proteins 0.000 claims 3
- 101150083238 bsc7 gene Proteins 0.000 claims 3
- 101150044905 ctpC gene Proteins 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 101150009128 fhs gene Proteins 0.000 claims 3
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 claims 3
- 101150032444 gadC gene Proteins 0.000 claims 3
- 101150077981 groEL gene Proteins 0.000 claims 3
- 101150108643 hycA gene Proteins 0.000 claims 3
- 101150052034 hycB gene Proteins 0.000 claims 3
- 101150031015 hycH gene Proteins 0.000 claims 3
- 101150026607 hycI gene Proteins 0.000 claims 3
- 101150082486 hyfE gene Proteins 0.000 claims 3
- 101150020134 hyfF gene Proteins 0.000 claims 3
- 101150019385 hypB gene Proteins 0.000 claims 3
- 101150075728 hypC gene Proteins 0.000 claims 3
- 101150013500 hypD gene Proteins 0.000 claims 3
- 101150070280 hypE gene Proteins 0.000 claims 3
- 101150007905 hypF gene Proteins 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 101150051471 metF gene Proteins 0.000 claims 3
- 101150017594 mtaA gene Proteins 0.000 claims 3
- 101150081621 mtaB gene Proteins 0.000 claims 3
- 101150096860 thlA gene Proteins 0.000 claims 3
- 101150000552 ydbK gene Proteins 0.000 claims 3
- SJZRECIVHVDYJC-UHFFFAOYSA-N 4-hydroxybutyric acid Chemical compound OCCCC(O)=O SJZRECIVHVDYJC-UHFFFAOYSA-N 0.000 claims 2
- 229940006015 4-hydroxybutyric acid Drugs 0.000 claims 2
- 101150031273 BDH1 gene Proteins 0.000 claims 2
- 101100338533 Clostridium aminobutyricum abfD gene Proteins 0.000 claims 2
- 101000636215 Crotalus durissus terrificus Crotamine Proteins 0.000 claims 2
- 101100350700 Escherichia coli (strain K12) paaB gene Proteins 0.000 claims 2
- 101100350708 Escherichia coli (strain K12) paaF gene Proteins 0.000 claims 2
- 101100350709 Escherichia coli (strain K12) paaG gene Proteins 0.000 claims 2
- 101100082074 Escherichia coli (strain K12) paaZ gene Proteins 0.000 claims 2
- 101100236497 Klebsiella aerogenes maoC gene Proteins 0.000 claims 2
- 101100331406 Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) Msed_1933 gene Proteins 0.000 claims 2
- 108091000080 Phosphotransferase Proteins 0.000 claims 2
- 101100463818 Pseudomonas oleovorans phaC1 gene Proteins 0.000 claims 2
- 101100350716 Pseudomonas putida paaK gene Proteins 0.000 claims 2
- 101100332697 Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) fadB1 gene Proteins 0.000 claims 2
- 101100280476 Streptococcus pneumoniae (strain ATCC BAA-255 / R6) fabM gene Proteins 0.000 claims 2
- 101100493797 Thauera butanivorans (strain ATCC 43655 / DSM 2080 / JCM 20651 / NBRC 103042 / IAM 12574 / Bu B1211) bdh gene Proteins 0.000 claims 2
- OJFDKHTZOUZBOS-CITAKDKDSA-N acetoacetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 OJFDKHTZOUZBOS-CITAKDKDSA-N 0.000 claims 2
- 101150056881 mcr gene Proteins 0.000 claims 2
- 101150037784 paaA gene Proteins 0.000 claims 2
- 101150046540 phaA gene Proteins 0.000 claims 2
- 101150110984 phaB gene Proteins 0.000 claims 2
- 102000020233 phosphotransferase Human genes 0.000 claims 2
- 101150078509 ADH2 gene Proteins 0.000 claims 1
- 101150026777 ADH5 gene Proteins 0.000 claims 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- 101100460671 Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) norA gene Proteins 0.000 claims 1
- 101100098786 Bacillus subtilis (strain 168) tapA gene Proteins 0.000 claims 1
- 101150116295 CAT2 gene Proteins 0.000 claims 1
- 101100110009 Caenorhabditis elegans asd-2 gene Proteins 0.000 claims 1
- 101100326920 Caenorhabditis elegans ctl-1 gene Proteins 0.000 claims 1
- 101100385572 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) ctfA gene Proteins 0.000 claims 1
- 101100385573 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) ctfB gene Proteins 0.000 claims 1
- 101100269671 Dictyostelium discoideum alrA gene Proteins 0.000 claims 1
- 101100321116 Escherichia coli (strain K12) yqhD gene Proteins 0.000 claims 1
- 108700023479 Glutamate 5-kinases Proteins 0.000 claims 1
- 101000716795 Homo sapiens Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial Proteins 0.000 claims 1
- 101100433987 Latilactobacillus sakei subsp. sakei (strain 23K) ackA1 gene Proteins 0.000 claims 1
- 101100456321 Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) Msed_0709 gene Proteins 0.000 claims 1
- 101100269700 Mycolicibacterium smegmatis alr gene Proteins 0.000 claims 1
- 101100126846 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) katG gene Proteins 0.000 claims 1
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 claims 1
- 102100020869 Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial Human genes 0.000 claims 1
- 101150006213 ackA gene Proteins 0.000 claims 1
- 101150079502 acr1 gene Proteins 0.000 claims 1
- 101150014383 adhE gene Proteins 0.000 claims 1
- 101150063145 atoA gene Proteins 0.000 claims 1
- 101150008413 atoD gene Proteins 0.000 claims 1
- 101150008745 bphG gene Proteins 0.000 claims 1
- 101150031417 buk1 gene Proteins 0.000 claims 1
- 101150091767 buk2 gene Proteins 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 101150046501 proB gene Proteins 0.000 claims 1
- 101150031436 sucD gene Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13810808P | 2008-12-16 | 2008-12-16 | |
| US61/138,108 | 2008-12-16 | ||
| PCT/US2009/050757 WO2010071697A1 (en) | 2008-12-16 | 2009-07-15 | Microorganisms and methods for conversion of syngas and other carbon sources to useful products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012511928A JP2012511928A (ja) | 2012-05-31 |
| JP2012511928A5 true JP2012511928A5 (https=) | 2012-09-06 |
Family
ID=42269103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011542150A Pending JP2012511928A (ja) | 2008-12-16 | 2009-07-15 | 合成ガス及び他の炭素源の有用な製品への変換のための微生物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US8129155B2 (https=) |
| EP (1) | EP2373781A4 (https=) |
| JP (1) | JP2012511928A (https=) |
| KR (1) | KR20110097951A (https=) |
| CN (1) | CN102307986A (https=) |
| AU (1) | AU2009327490A1 (https=) |
| BR (1) | BRPI0922276A2 (https=) |
| CA (1) | CA2746952A1 (https=) |
| WO (1) | WO2010071697A1 (https=) |
| ZA (1) | ZA201104462B (https=) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7947483B2 (en) | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
| CN101978042B (zh) | 2008-01-22 | 2017-03-08 | 基因组股份公司 | 利用合成气或其它气态碳源和甲醇的方法和有机体 |
| CN102066551B (zh) * | 2008-03-27 | 2013-10-09 | 基因组股份公司 | 用于产生己二酸和其他化合物的微生物 |
| WO2009135074A2 (en) * | 2008-05-01 | 2009-11-05 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
| US8129154B2 (en) | 2008-06-17 | 2012-03-06 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
| US7858350B2 (en) | 2008-09-10 | 2010-12-28 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol |
| US9957534B2 (en) | 2008-11-06 | 2018-05-01 | Kiverdi, Inc. | Engineered CO2-fixing chemotrophic microorganisms producing carbon-based products and methods of using the same |
| WO2013148348A1 (en) * | 2012-03-28 | 2013-10-03 | Kiverdi, Inc. | Engineered co2-fixing chemotrophic microorganisms producing carbon-based products and methods of using the same |
| US20100184173A1 (en) * | 2008-11-14 | 2010-07-22 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
| EP2373781A4 (en) | 2008-12-16 | 2012-10-10 | Genomatica Inc | MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS |
| EP4321615A3 (en) | 2009-04-30 | 2024-02-21 | Genomatica, Inc. | Organisms for the production of 1,3-butanediol |
| SI3199511T1 (sl) | 2009-06-04 | 2020-07-31 | Genomatica, Inc. | Proces separacije komponent fermentacijske brozge |
| WO2010141920A2 (en) | 2009-06-04 | 2010-12-09 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol and related methods |
| EP2440669A4 (en) * | 2009-06-10 | 2013-08-28 | Genomatica Inc | MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL |
| EP2933338A3 (en) * | 2009-09-09 | 2016-01-06 | Genomatica, Inc. | Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids |
| US8377666B2 (en) | 2009-10-13 | 2013-02-19 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto |
| US8530210B2 (en) | 2009-11-25 | 2013-09-10 | Genomatica, Inc. | Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone |
| FR2953596B1 (fr) * | 2009-12-09 | 2013-12-20 | Rhodia Operations | Procede et installation de determination, d'au moins un parametre d'une transformation faisant intervenir un transfert entre un gaz et un liquide |
| US8268607B2 (en) | 2009-12-10 | 2012-09-18 | Genomatica, Inc. | Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol |
| EP2529011A4 (en) | 2010-01-29 | 2015-07-15 | Genomatica Inc | MICROORGANISMS AND METHODS FOR BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE |
| US9084467B2 (en) | 2010-02-11 | 2015-07-21 | Metabolix, Inc. | Process for gamma-butyrolactone production |
| US8637286B2 (en) * | 2010-02-23 | 2014-01-28 | Genomatica, Inc. | Methods for increasing product yields |
| US8048661B2 (en) | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
| US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
| KR101814648B1 (ko) | 2010-05-05 | 2018-01-04 | 게노마티카 인코포레이티드 | 부타디엔을 생합성하기 위한 미생물 및 방법 |
| BR112013001635A2 (pt) | 2010-07-26 | 2016-05-24 | Genomatica Inc | micro-organismo e métodos para a biossíntese de aromáticos, 2, 4-pentadienoato e 1,3-butadieno |
| US8927254B2 (en) | 2010-09-29 | 2015-01-06 | University Of Georgia Research Foundation, Inc. | Pyrococcus furiosus strains and methods of using same |
| EP2632943A1 (en) | 2010-10-29 | 2013-09-04 | Novozymes A/S | Polypeptides having succinyl-coa:aceto acetate transferase activity and polynucleotides encoding same |
| JP2013544083A (ja) | 2010-10-29 | 2013-12-12 | ノボザイムス アクティーゼルスカブ | 組み換えn−プロパノール及びイソプロパノール生産 |
| US20140039143A1 (en) * | 2010-12-17 | 2014-02-06 | Total Research & Technology Feluy | Process for producing propylene from syngas via fermentative propanol production and dehydration |
| BR112013021524A2 (pt) * | 2011-02-25 | 2017-06-13 | Lanzatech New Zealand Ltd | micro-organismos recombinantes e usos dos mesmos |
| US9410130B2 (en) | 2011-02-25 | 2016-08-09 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
| US9365868B2 (en) | 2011-02-25 | 2016-06-14 | Lanzatech New Zealand Limited | Fermentation process for producing isopropanol using a recombinant microorganism |
| US8673603B2 (en) | 2011-03-31 | 2014-03-18 | Lanzatech New Zealand Limited | Fermentation process for controlling butanediol production |
| US8962333B2 (en) | 2011-04-04 | 2015-02-24 | University Of Georgia Research Foundation, Inc. | Restriction/modification polypeptides, polynucleotides, and methods |
| WO2012177601A2 (en) * | 2011-06-22 | 2012-12-27 | Genomatica, Inc. | Microorganisms for producing isobutanol and methods related thereto |
| US9169486B2 (en) | 2011-06-22 | 2015-10-27 | Genomatica, Inc. | Microorganisms for producing butadiene and methods related thereto |
| WO2012177943A1 (en) | 2011-06-22 | 2012-12-27 | Genomatica, Inc. | Microorganisms for producing 1,4-butanediol and methods related thereto |
| ES2599482T3 (es) | 2011-07-29 | 2017-02-01 | Mitsui Chemicals, Inc. | Microorganismo que tiene un ciclo de fijación de dióxido de carbono introducido en el mismo |
| EP2743352A4 (en) * | 2011-08-11 | 2015-03-11 | Mitsui Chemicals Inc | PROCESS FOR THE PREPARATION OF ISOPROPYL ALCOHOL BY A CONTINUOUS CULTURE |
| WO2013178699A1 (en) | 2012-05-31 | 2013-12-05 | Novozymes A/S | Isopropanol production by bacterial hosts |
| WO2013184602A2 (en) | 2012-06-04 | 2013-12-12 | Genomatica, Inc. | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds |
| CN104350034B (zh) | 2012-06-08 | 2018-07-31 | Cj 第一制糖株式会社 | 可再生丙烯酸生产和自其制备的产物 |
| KR102079275B1 (ko) * | 2012-06-08 | 2020-02-19 | 란자테크 뉴질랜드 리미티드 | 재조합 미생물 및 그에 대한 용도 |
| US20140024872A1 (en) | 2012-07-13 | 2014-01-23 | Calysta Energy, Llc | Biorefinery system, methods and compositions thereof |
| US9309542B2 (en) | 2012-08-17 | 2016-04-12 | University Of Georgia Research Foundation, Inc. | Recombinant Caldicellulosiruptor bescii and methods of use |
| US9657316B2 (en) | 2012-08-27 | 2017-05-23 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,4-butanediol related thereto |
| US9587256B2 (en) | 2012-09-06 | 2017-03-07 | University Of Georgia Research Foundation, Inc. | Sequestration of carbon dioxide with hydrogen to useful products |
| EP2899273A4 (en) * | 2012-09-24 | 2016-03-02 | Showa Denko Kk | GEN, MICROORGANISM, CONVERSION METHOD AND METHOD OF MANUFACTURE |
| WO2014045781A1 (ja) * | 2012-09-24 | 2014-03-27 | 昭和電工株式会社 | ブタンジオール類の製造方法 |
| US10501714B2 (en) | 2012-10-08 | 2019-12-10 | Calysta Energy, Inc. | Gas-fed fermentation systems |
| WO2014068010A1 (en) | 2012-10-31 | 2014-05-08 | Novozymes A/S | Isopropanol production by bacterial hosts |
| US9909150B2 (en) | 2012-11-05 | 2018-03-06 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,2-propanediol, n-propanol, 1,3-propanediol, or glycerol related thereto |
| US9346902B2 (en) | 2012-11-05 | 2016-05-24 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 3-hydroxyisobutyrate or methacrylic acid related thereto |
| US20160068463A1 (en) | 2012-11-14 | 2016-03-10 | Metabolix, Inc. | Production of salts of 4-hydroxybutyrate using biobased raw materials |
| WO2014076232A2 (en) | 2012-11-19 | 2014-05-22 | Novozymes A/S | Isopropanol production by recombinant hosts using an hmg-coa intermediate |
| EP2924123A4 (en) * | 2012-11-26 | 2016-07-06 | Showa Denko Kk | 1,4-BANDANOL PRODUCTION METHOD AND MICROORGANISM |
| JP6208146B2 (ja) | 2012-12-05 | 2017-10-04 | 昭和電工株式会社 | 1,4−ブタンジオールの製造方法、微生物及び遺伝子 |
| TWI599641B (zh) * | 2012-12-14 | 2017-09-21 | 捷恩智股份有限公司 | 液晶組成物及其用途、以及液晶顯示元件 |
| US9469860B2 (en) * | 2013-01-18 | 2016-10-18 | Synata Bio, Inc. | Method for production of n-butanol from syngas using syntrophic co-cultures of anaerobic microorganisms |
| KR20150108367A (ko) * | 2013-01-21 | 2015-09-25 | 세키스이가가쿠 고교가부시키가이샤 | 재조합 세포, 및 1,4-부탄디올의 생산 방법 |
| MY174741A (en) | 2013-01-24 | 2020-05-13 | Mitsui Chemicals Inc | Microorganism for production of chemicals derived from acetyl-coa |
| CN104718292B (zh) | 2013-01-24 | 2019-09-10 | 三井化学株式会社 | 导入了二氧化碳固定循环的微生物 |
| BR112015020904A2 (pt) | 2013-03-15 | 2017-10-10 | Genomatica Inc | microrganismos e métodos para produção de butadieno e compostos relacionados por assimilação de formiato |
| EP3004362A4 (en) * | 2013-06-05 | 2017-01-11 | Lanzatech New Zealand Limited | Recombinant microorganisms exhibiting increased flux through a fermentation pathway |
| KR102113254B1 (ko) | 2013-08-23 | 2020-05-21 | 삼성전자주식회사 | 1,4―bdo 생산을 위한 유전자 스크리닝 방법 |
| EP4296364B1 (en) | 2013-12-03 | 2025-12-03 | Genomatica, Inc. | Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis |
| US10597684B2 (en) | 2013-12-27 | 2020-03-24 | Genomatica, Inc. | Methods and organisms with increased carbon flux efficiencies |
| US10337043B2 (en) | 2014-01-16 | 2019-07-02 | Calysta, Inc. | Carbohydrate-enriched recombinant microorganisms |
| WO2015108777A1 (en) | 2014-01-16 | 2015-07-23 | Papoutsakis Eleftherios T | Synthetic methylotrophy to liquid fuels and chemicals |
| EP2902477A1 (de) * | 2014-01-29 | 2015-08-05 | Siemens VAI Metals Technologies GmbH | Erzeugung von C2-C5 Kohlenwasserstoffen mittels Bakterienfermentation |
| JP6309304B2 (ja) * | 2014-02-24 | 2018-04-11 | 積水化学工業株式会社 | 組換え細胞、並びに、1,4−ブタンジオールの生産方法 |
| WO2015158716A1 (en) | 2014-04-16 | 2015-10-22 | Novamont S.P.A. | Process for the production of 1,4-butanediol |
| JP6034332B2 (ja) | 2014-05-30 | 2016-11-30 | トヨタ自動車株式会社 | 組換え微生物及び当該組換え微生物を用いた物質製造方法 |
| JP6189793B2 (ja) | 2014-05-30 | 2017-08-30 | トヨタ自動車株式会社 | 組換え微生物及び当該組換え微生物を用いた物質製造方法 |
| ES2728726T3 (es) * | 2014-08-11 | 2019-10-28 | Lanzatech New Zealand Ltd | Bacteria modificada por ingeniería genética con actividad de monóxido de carbono deshidrogenasa (CODH) reducida |
| EP3741865B1 (en) | 2014-09-18 | 2024-03-13 | Genomatica, Inc. | Non-natural microbial organisms with improved energetic efficiency |
| TWI541353B (zh) * | 2014-12-25 | 2016-07-11 | 財團法人工業技術研究院 | 產生嗜熱性鹼性蛋白酶生產菌屬(Tepidimonas)之胞外蛋白的方法 |
| CN107404882A (zh) | 2015-02-27 | 2017-11-28 | 白狗实验室有限公司 | 用于生产丙酮、异丙醇、丁酸、其他生物产品及其混合物的混合营养发酵方法 |
| JP6608936B2 (ja) * | 2015-09-02 | 2019-11-20 | 積水化学工業株式会社 | 組換え細胞、組換え細胞の製造方法、並びに、1,4−ブタンジオールの生産方法 |
| WO2017059244A1 (en) * | 2015-10-02 | 2017-04-06 | White Dog Labs, Inc. | A method for producing a bioproduct selected from acetone, isopropanol and combinations thereof |
| US11441128B2 (en) | 2015-10-30 | 2022-09-13 | Genomatica, Inc. | Methanol dehydrogenase fusion proteins |
| FR3051799B1 (fr) | 2016-05-31 | 2018-06-15 | IFP Energies Nouvelles | Procede de production de btx par pyrolyse catalytique a partir de biomasse avec injection de composes oxygenes |
| FR3051800B1 (fr) | 2016-05-31 | 2018-06-15 | IFP Energies Nouvelles | Procede de production de btx par pyrolyse catalytique a partir de biomasse sans recycle de composes oxygenes |
| US10829789B2 (en) | 2016-12-21 | 2020-11-10 | Creatus Biosciences Inc. | Methods and organism with increased xylose uptake |
| CN111601648B (zh) | 2017-11-27 | 2022-08-02 | 诺瓦蒙特股份公司 | 用于生产来自可再生资源的1,4-丁二醇的方法和由其获得的聚酯 |
| US20210079334A1 (en) | 2018-01-30 | 2021-03-18 | Genomatica, Inc. | Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| WO2020006058A2 (en) | 2018-06-26 | 2020-01-02 | Genomatica, Inc. | Engineered microorganisms with g3p---> 3pg enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy |
| US10864848B2 (en) * | 2018-12-21 | 2020-12-15 | Continental Automotive Systems, Inc. | Reverse lights trailer hitch assist |
| IT202000013243A1 (it) | 2020-06-04 | 2021-12-04 | Novamont Spa | Processo per la purificazione di una miscela di dioli |
| US20220098560A1 (en) * | 2020-09-25 | 2022-03-31 | Lanzatech, Inc. | Recombinant microorganisms and uses therefor |
| FR3114594B1 (fr) | 2020-09-29 | 2023-11-10 | Ifp Energies Now | Production d’aromatiques et d'éthanol par pyrolyse, conversion de gaz à l'eau inversée, et fermentation. |
| FR3114596B1 (fr) | 2020-09-29 | 2023-11-24 | Ifp Energies Now | Production d’aromatiques par conversion de gaz à l'eau inversée, fermentation et recyclage vers pyrolyse. |
| FR3114595B1 (fr) | 2020-09-29 | 2023-11-24 | Ifp Energies Now | Production d’aromatiques par conversion de gaz à l'eau inversée, fermentation et aromatisation. |
| CN113106047B (zh) * | 2021-04-12 | 2024-01-26 | 南京工业大学 | 一种重组食甲基丁酸杆菌及其构建方法与应用 |
| FR3126993A1 (fr) | 2021-09-10 | 2023-03-17 | IFP Energies Nouvelles | Production d'éthanol par combustion en boucle chimique, conversion de gaz à l'eau inversée, et fermentation. |
| FR3126992A1 (fr) | 2021-09-10 | 2023-03-17 | IFP Energies Nouvelles | Production d'éthanol par oxycombustion, conversion de gaz à l'eau inversée, et fermentation. |
| KR102690861B1 (ko) * | 2021-10-18 | 2024-08-05 | 한국과학기술원 | 로그기에서 부탄올을 생산하는 클로스트리듐 균주 |
| IT202100030572A1 (it) | 2021-12-02 | 2023-06-02 | Novamont Spa | 1,3-butandiolo purificato da una miscela di dioli |
| CN114807206B (zh) * | 2022-03-28 | 2023-03-21 | 珠海麦得发生物科技股份有限公司 | 合成聚(3-羟基丁酸酯-co-4-羟基丁酸酯)的菌株及其构建方法和应用 |
| CN115170166B (zh) * | 2022-09-06 | 2023-04-11 | 山东省市场监管监测中心 | 一种用于判断垄断行为的大数据感知方法及系统 |
| IT202300019440A1 (it) | 2023-09-21 | 2025-03-21 | Novamont Spa | Idrolizzato proteico di cellule di escherichia coli residue da un processo di fermentazione |
Family Cites Families (167)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3513209A (en) * | 1968-08-19 | 1970-05-19 | Du Pont | Method of making 1,4-cyclohexadiene |
| US4076948A (en) * | 1968-10-10 | 1978-02-28 | El Paso Products Company | Process for treatment of adipic acid mother liquor |
| GB1230276A (https=) | 1968-12-09 | 1971-04-28 | ||
| US3965182A (en) * | 1969-10-02 | 1976-06-22 | Ethyl Corporation | Preparation of aniline from phenol and ammonia |
| JPS4831084B1 (https=) | 1970-09-04 | 1973-09-26 | ||
| GB1344557A (en) | 1972-06-23 | 1974-01-23 | Mitsubishi Petrochemical Co | Process for preparing 1,4-butanediol |
| JPS5543759B2 (https=) * | 1972-06-28 | 1980-11-07 | ||
| DE2455617C3 (de) * | 1974-11-23 | 1982-03-18 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von Butandiol und/oder Tetrahydrofuran über die Zwischenstufe des γ-Butyrolactons |
| DE2501499A1 (de) | 1975-01-16 | 1976-07-22 | Hoechst Ag | Verfahren zur herstellung von butandiol-(1.4) |
| US4190495A (en) * | 1976-09-27 | 1980-02-26 | Research Corporation | Modified microorganisms and method of preparing and using same |
| US4301077A (en) | 1980-12-22 | 1981-11-17 | Standard Oil Company | Process for the manufacture of 1-4-butanediol and tetrahydrofuran |
| JPS60114197A (ja) | 1983-11-25 | 1985-06-20 | Agency Of Ind Science & Technol | 微生物によるジカルボン酸の製造法 |
| US4871667A (en) * | 1984-11-26 | 1989-10-03 | Agency Of Industrial Science & Technology | Process for preparing muconic acid |
| US4652685A (en) * | 1985-11-15 | 1987-03-24 | General Electric Company | Hydrogenation of lactones to glycols |
| US5143834A (en) * | 1986-06-11 | 1992-09-01 | Glassner David A | Process for the production and purification of succinic acid |
| EP0249773B1 (en) * | 1986-06-11 | 1992-12-16 | Michigan Biotechnology Institute | A process for the production of succinic acid by anaerobic fermentation |
| US5168055A (en) | 1986-06-11 | 1992-12-01 | Rathin Datta | Fermentation and purification process for succinic acid |
| US5182199A (en) * | 1987-05-27 | 1993-01-26 | Hartley Brian S | Thermophilic ethanol production in a two-stage closed system |
| EP0556387B1 (en) * | 1988-04-27 | 1995-08-09 | Daicel Chemical Industries, Ltd. | Process for preparing optically active 1,3-butanediol |
| WO1990012888A1 (en) * | 1989-04-27 | 1990-11-01 | Biocontrol Systems, Incorporated | Precipitate test for microorganisms |
| US5192673A (en) * | 1990-04-30 | 1993-03-09 | Michigan Biotechnology Institute | Mutant strain of C. acetobutylicum and process for making butanol |
| US5079143A (en) * | 1990-05-02 | 1992-01-07 | The Upjohn Company | Method of indentifying compounds useful as antiparasitic drugs |
| EP0769557B1 (en) * | 1990-10-15 | 2000-11-15 | Daicel Chemical Industries, Ltd. | Process for producing optically active 1,3-butanediol |
| US5173429A (en) | 1990-11-09 | 1992-12-22 | The Board Of Trustees Of The University Of Arkansas | Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism |
| IL100572A (en) | 1991-01-03 | 1997-01-10 | Lepetit Spa | Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them |
| US5416020A (en) * | 1992-09-29 | 1995-05-16 | Bio-Technical Resources | Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid |
| US5807722A (en) * | 1992-10-30 | 1998-09-15 | Bioengineering Resources, Inc. | Biological production of acetic acid from waste gases with Clostridium ljungdahlii |
| US6136577A (en) * | 1992-10-30 | 2000-10-24 | Bioengineering Resources, Inc. | Biological production of ethanol from waste gases with Clostridium ljungdahlii |
| FR2702492B1 (fr) * | 1993-03-12 | 1995-05-24 | Rhone Poulenc Chimie | Procédé de production par fermentation d'acide itaconique. |
| US5487987A (en) * | 1993-09-16 | 1996-01-30 | Purdue Research Foundation | Synthesis of adipic acid from biomass-derived carbon sources |
| US5521075A (en) * | 1994-12-19 | 1996-05-28 | Michigan Biotechnology Institute | Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants |
| US5504004A (en) * | 1994-12-20 | 1996-04-02 | Michigan Biotechnology Institute | Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms |
| US5700934A (en) | 1995-03-01 | 1997-12-23 | Dsm N.V. | Process for the preparation of epsilon-caprolactam and epsilon-caprolactam precursors |
| US5478952A (en) | 1995-03-03 | 1995-12-26 | E. I. Du Pont De Nemours And Company | Ru,Re/carbon catalyst for hydrogenation in aqueous solution |
| US5863782A (en) * | 1995-04-19 | 1999-01-26 | Women's And Children's Hospital | Synthetic mammalian sulphamidase and genetic sequences encoding same |
| US5686276A (en) | 1995-05-12 | 1997-11-11 | E. I. Du Pont De Nemours And Company | Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism |
| FR2736927B1 (fr) * | 1995-07-18 | 1997-10-17 | Rhone Poulenc Fibres & Polymer | Enzymes a activite amidase, outils genetiques et microorganismes hotes permettant leur obtention et procede d'hydrolyse mettant en oeuvre lesdites enzymes |
| US5573931A (en) | 1995-08-28 | 1996-11-12 | Michigan Biotechnology Institute | Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants |
| US5770435A (en) * | 1995-11-02 | 1998-06-23 | University Of Chicago | Mutant E. coli strain with increased succinic acid production |
| US5869301A (en) * | 1995-11-02 | 1999-02-09 | Lockhead Martin Energy Research Corporation | Method for the production of dicarboxylic acids |
| US5908924A (en) * | 1996-02-27 | 1999-06-01 | Michigan State University | Cloning and expression of the gene encoding thermoanaerobacter ethanolicus 39E secondary-alcohol dehydrogenase and enzyme biochemical characterization |
| US5958745A (en) * | 1996-03-13 | 1999-09-28 | Monsanto Company | Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants |
| KR100387301B1 (ko) * | 1996-07-01 | 2003-06-12 | 바이오 엔지니어링 리소스 인코포레이티드 | 폐가스로부터의 생성물의 생물학적 제조방법 |
| KR100459818B1 (ko) * | 1996-09-02 | 2004-12-03 | 이. 아이. 두퐁 드 느무르 앤드 컴퍼니 | ε-카프로락탐의 제조방법 |
| EP0977865A1 (en) * | 1997-02-13 | 2000-02-09 | James Madison University | Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units |
| KR100516986B1 (ko) * | 1997-02-19 | 2005-09-26 | 코닌클리즈케 디에스엠 엔.브이. | 6-아미노카프론산 유도체를 과열 수증기와 접촉시킴으로써 촉매 없이 카프로락탐을 제조하는 방법 |
| US6274790B1 (en) * | 1997-04-14 | 2001-08-14 | The University Of British Columbia | Nucleic acids encoding a plant enzyme involved in very long chain fatty acid synthesis |
| KR19990013007A (ko) * | 1997-07-31 | 1999-02-25 | 박원훈 | 형질전환된 대장균 ss373(kctc 8818p)과 이를 이용한숙신산의 생산방법 |
| JPH11103863A (ja) * | 1997-10-08 | 1999-04-20 | Nippon Shokubai Co Ltd | マレイン酸異性化酵素遺伝子 |
| US6280986B1 (en) * | 1997-12-01 | 2001-08-28 | The United States Of America As Represented By The Secretary Of Agriculture | Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities |
| US20030087381A1 (en) * | 1998-04-13 | 2003-05-08 | University Of Georgia Research Foundation, Inc. | Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals |
| WO1999053035A1 (en) * | 1998-04-13 | 1999-10-21 | The University Of Georgia Research Foundation, Inc. | Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells |
| US6159738A (en) | 1998-04-28 | 2000-12-12 | University Of Chicago | Method for construction of bacterial strains with increased succinic acid production |
| DE19820652A1 (de) | 1998-05-08 | 1999-11-11 | Basf Ag | Kationische Rutheniumkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US6432686B1 (en) * | 1998-05-12 | 2002-08-13 | E. I. Du Pont De Nemours And Company | Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport |
| US6444784B1 (en) * | 1998-05-29 | 2002-09-03 | Exxonmobil Research & Engineering Company | Wax crystal modifiers (LAW657) |
| US6187569B1 (en) | 1998-07-02 | 2001-02-13 | E. I. Du Pont De Nemours And Company | Microbial production of terephthalic acid and isophthalic acid |
| EP1097222A1 (en) * | 1998-07-15 | 2001-05-09 | E.I. Du Pont De Nemours And Company | Tetrahydrofolate metabolism enzymes |
| DE19856136C2 (de) * | 1998-12-04 | 2002-10-24 | Pasteur Institut | Verfahren und Vorrichtung zur Selektion beschleunigter Proliferation lebender Zellen in Suspension |
| WO2000046405A2 (en) * | 1999-02-02 | 2000-08-10 | Bernhard Palsson | Methods for identifying drug targets based on genomic sequence data |
| US6686310B1 (en) * | 1999-02-09 | 2004-02-03 | E. I. Du Pont De Nemours And Company | High surface area sol-gel route prepared hydrogenation catalysts |
| US6365376B1 (en) * | 1999-02-19 | 2002-04-02 | E. I. Du Pont De Nemours And Company | Genes and enzymes for the production of adipic acid intermediates |
| US6448473B1 (en) * | 1999-03-05 | 2002-09-10 | Monsanto Technology Llc | Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways |
| US6485947B1 (en) | 1999-05-21 | 2002-11-26 | Cargill Dow Polymers, Llc | Production of lactate using crabtree negative organisms in varying culture conditions |
| US6852517B1 (en) * | 1999-08-30 | 2005-02-08 | Wisconsin Alumni Research Foundation | Production of 3-hydroxypropionic acid in recombinant organisms |
| US6660857B2 (en) | 2000-02-03 | 2003-12-09 | Dsm N.V. | Process for the preparation of ε-caprolactam |
| US6878861B2 (en) * | 2000-07-21 | 2005-04-12 | Washington State University Research Foundation | Acyl coenzyme A thioesterases |
| DK1303629T3 (da) | 2000-07-25 | 2006-10-30 | Emmaus Foundation Inc | Fremgangsmåde til forögelse af ethanolproduktion fra mikrobiel fermetering |
| CA2429039A1 (en) * | 2000-11-20 | 2002-05-30 | Cargill, Incorporated | 3-hydroxypropionic acid and other organic compounds |
| US7109010B2 (en) * | 2000-11-22 | 2006-09-19 | Nature Works Llc | Methods and materials for the synthesis of organic products |
| CN1358841A (zh) | 2000-12-11 | 2002-07-17 | 云南省微生物研究所 | 云南链霉菌 |
| US7501268B2 (en) * | 2000-12-28 | 2009-03-10 | Toyota Jidosha Kabushiki Kaisha | Methods of producing prenyl alcohols |
| JP4776146B2 (ja) | 2001-01-10 | 2011-09-21 | ザ・ペン・ステート・リサーチ・ファンデーション | 細胞代謝をモデル化する方法及びシステム |
| US7127379B2 (en) | 2001-01-31 | 2006-10-24 | The Regents Of The University Of California | Method for the evolutionary design of biochemical reaction networks |
| CA2439260C (en) * | 2001-03-01 | 2012-10-23 | The Regents Of The University Of California | Models and methods for determining systemic properties of regulated reaction networks |
| US6743610B2 (en) * | 2001-03-30 | 2004-06-01 | The University Of Chicago | Method to produce succinic acid from raw hydrolysates |
| JP4630486B2 (ja) * | 2001-05-28 | 2011-02-09 | ダイセル化学工業株式会社 | 新規な(r)−2,3−ブタンジオール脱水素酵素、その製造方法、及びこれを利用した光学活性アルコールの製造方法 |
| CA2356540A1 (en) * | 2001-08-30 | 2003-02-28 | Emory University | Expressed dna sequences involved in mitochondrial functions |
| MXPA04004194A (es) * | 2001-11-02 | 2005-03-31 | Rice University | Sistema de recirculacion para la manipulacion de disponibilidad de nadh intracelular. |
| ES2329778T3 (es) | 2002-01-18 | 2009-12-01 | Novozymes A/S | 2,3-aminomutasa de alanina. |
| WO2003066863A1 (fr) | 2002-02-06 | 2003-08-14 | Showa Denko K.K. | Gene reductase d'un compose carbonyle alpha-substitue-alpha, beta-insature |
| US20030224363A1 (en) | 2002-03-19 | 2003-12-04 | Park Sung M. | Compositions and methods for modeling bacillus subtilis metabolism |
| CA2480216A1 (en) * | 2002-03-29 | 2003-10-09 | Genomatica, Inc. | Human metabolic models and methods |
| JPWO2003095651A1 (ja) | 2002-05-10 | 2005-09-15 | 協和醗酵工業株式会社 | メバロン酸の製造方法 |
| US7856317B2 (en) | 2002-06-14 | 2010-12-21 | Genomatica, Inc. | Systems and methods for constructing genomic-based phenotypic models |
| US7826975B2 (en) * | 2002-07-10 | 2010-11-02 | The Penn State Research Foundation | Method for redesign of microbial production systems |
| AU2003256480B2 (en) * | 2002-07-10 | 2008-03-06 | The Penn State Research Foundation | Method for determining gene knockout strategies |
| US7413878B2 (en) * | 2002-07-15 | 2008-08-19 | Kosan Biosciences, Inc. | Recombinant host cells expressing atoAD and capable of making a polyketide using a starter unit |
| KR101148255B1 (ko) * | 2002-10-04 | 2012-08-08 | 다니스코 유에스 인크. | 고수율을 갖는 1,3-프로판디올의 생물학적 제조 방법 |
| US7734420B2 (en) * | 2002-10-15 | 2010-06-08 | The Regents Of The University Of California | Methods and systems to identify operational reaction pathways |
| AU2003287625A1 (en) * | 2002-11-06 | 2004-06-03 | University Of Florida | Materials and methods for the efficient production of acetate and other products |
| EP1603857A4 (en) | 2003-01-13 | 2006-05-17 | Cargill Inc | PROCESS FOR PRODUCING INDUSTRIAL CHEMICALS |
| WO2004074495A1 (ja) | 2003-02-24 | 2004-09-02 | Research Institute Of Innovative Technology For The Earth | 微生物による高効率水素製造方法 |
| RU2268300C2 (ru) * | 2003-04-07 | 2006-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA |
| ATE462002T1 (de) | 2003-07-29 | 2010-04-15 | Res Inst Innovative Tech Earth | Transformanten eines coryneformen bakteriums und deren verwendung in verfahren zur produktion von dicarbonsäure |
| US7927859B2 (en) * | 2003-08-22 | 2011-04-19 | Rice University | High molar succinate yield bacteria by increasing the intracellular NADH availability |
| EP1672067B1 (en) | 2003-09-17 | 2015-11-11 | Mitsubishi Chemical Corporation | Process for producing non-amino organic acid |
| US7244610B2 (en) * | 2003-11-14 | 2007-07-17 | Rice University | Aerobic succinate production in bacteria |
| FR2864967B1 (fr) * | 2004-01-12 | 2006-05-19 | Metabolic Explorer Sa | Microorganisme evolue pour la production de 1,2-propanediol |
| BRPI0506942B1 (pt) * | 2004-01-19 | 2015-07-28 | Dsm Ip Assets B.V. | Síntese bioquímica de ácido 6-amino capróico |
| US7608700B2 (en) | 2004-03-08 | 2009-10-27 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor |
| DE102004031177A1 (de) * | 2004-06-29 | 2006-01-19 | Henkel Kgaa | Neue Geruchsstoffe bildende Genprodukte von Bacillus licheniformis und darauf aufbauende verbesserte biotechnologische Produktionsverfahren |
| WO2006020663A2 (en) * | 2004-08-09 | 2006-02-23 | Rice University | Aerobic succinate production in bacteria |
| US7124679B2 (en) * | 2004-08-25 | 2006-10-24 | L&P Property Management Company | Lower guide track for down packing press apparatus and method |
| KR101245428B1 (ko) * | 2004-08-27 | 2013-03-19 | 라이스 유니버시티 | 숙신산 생산이 증가된 돌연변이 대장균 균주 |
| JP4712716B2 (ja) * | 2004-09-09 | 2011-06-29 | 財団法人地球環境産業技術研究機構 | プロモーター機能を有するdna断片 |
| JP2008513023A (ja) * | 2004-09-17 | 2008-05-01 | ライス ユニバーシティー | 高コハク酸生産細菌 |
| WO2006069174A2 (en) * | 2004-12-22 | 2006-06-29 | Rice University | Simultaneous anaerobic production of isoamyl acetate and succinic acid |
| JP2006204255A (ja) * | 2005-01-31 | 2006-08-10 | Canon Inc | アセチル−CoAアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法 |
| WO2006109312A2 (en) * | 2005-04-15 | 2006-10-19 | Vascular Biogenics Ltd. | Compositions containing beta 2-glycoprotein i-derived peptides for the prevention and/or treatment of vascular disease |
| KR100676160B1 (ko) | 2005-08-19 | 2007-02-01 | 한국과학기술원 | 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법 |
| KR100679638B1 (ko) * | 2005-08-19 | 2007-02-06 | 한국과학기술원 | 포메이트 디하이드로게나제 d 또는 e를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법 |
| JP2009507493A (ja) * | 2005-09-09 | 2009-02-26 | ジェノマティカ・インコーポレイテッド | 増殖連動型のコハク酸塩生成のための方法と生物 |
| US9297028B2 (en) * | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US20080274526A1 (en) | 2007-05-02 | 2008-11-06 | Bramucci Michael G | Method for the production of isobutanol |
| RU2394913C2 (ru) | 2005-10-26 | 2010-07-20 | Е.И.Дюпон Де Немур Энд Компани | Ферментативное получение четырехуглеродных спиртов |
| US8206970B2 (en) | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| US8017364B2 (en) * | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
| BRPI0806695A2 (pt) | 2007-01-12 | 2014-06-03 | Univ Colorado | Composições e métodos para aumentar a tolerância à produção de produtos químicos produzidos por microorganismos |
| US8673601B2 (en) | 2007-01-22 | 2014-03-18 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
| LT2821494T (lt) | 2007-03-16 | 2017-04-25 | Genomatica, Inc. | 1,4-butandiolio ir jo pirmtakų biosintezės būdai ir kompozicijos |
| CN101680007A (zh) | 2007-04-18 | 2010-03-24 | 纳幕尔杜邦公司 | 使用高活性酮醇酸还原异构酶来发酵生产异丁醇 |
| WO2008131286A1 (en) * | 2007-04-18 | 2008-10-30 | Gevo, Inc. | Engineered microorganisms for producing isopropanol |
| US20080274522A1 (en) | 2007-05-02 | 2008-11-06 | Bramucci Michael G | Method for the production of 2-butanone |
| WO2008144060A2 (en) * | 2007-05-17 | 2008-11-27 | Tetravitae Bioscience, Inc. | Methods and compositions for producing solvents |
| KR20100049012A (ko) | 2007-06-15 | 2010-05-11 | 에보니크 데구사 게엠베하 | 비타민 b12 시스템이 탈조절된 미생물 |
| EP2017344A1 (en) | 2007-07-20 | 2009-01-21 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Production of itaconic acid |
| US20100205857A1 (en) | 2007-07-23 | 2010-08-19 | Einte-Karst Dijk | Butanol production in a eukaryotic cell |
| WO2009045637A2 (en) | 2007-08-10 | 2009-04-09 | Genomatica, Inc. | Methods for the synthesis of acrylic acid and derivatives from fumaric acid |
| US7947483B2 (en) * | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
| EP2198039A4 (en) | 2007-10-12 | 2012-05-09 | Univ California | MODIFIED MICROORGANISMS FOR THE MANUFACTURE OF ISOPROPANOL |
| US8183028B2 (en) * | 2007-12-21 | 2012-05-22 | Ls9, Inc. | Methods and compositions for producing olefins |
| CN101978042B (zh) * | 2008-01-22 | 2017-03-08 | 基因组股份公司 | 利用合成气或其它气态碳源和甲醇的方法和有机体 |
| US20090246842A1 (en) | 2008-02-15 | 2009-10-01 | Gevo, Inc. | Engineered microorganisms for producing propanol |
| CA2728285A1 (en) | 2008-03-03 | 2009-09-11 | Joule Unlimited, Inc. | Engineered co2 fixing microorganisms producing carbon-based products of interest |
| EP2262901B1 (en) | 2008-03-05 | 2018-11-21 | Genomatica, Inc. | Primary alcohol producing organisms |
| CN102066551B (zh) | 2008-03-27 | 2013-10-09 | 基因组股份公司 | 用于产生己二酸和其他化合物的微生物 |
| WO2009135074A2 (en) | 2008-05-01 | 2009-11-05 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
| US8129154B2 (en) * | 2008-06-17 | 2012-03-06 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
| US20100021978A1 (en) | 2008-07-23 | 2010-01-28 | Genomatica, Inc. | Methods and organisms for production of 3-hydroxypropionic acid |
| WO2010022763A1 (en) | 2008-08-25 | 2010-03-04 | Metabolic Explorer | Method for the preparation of 2-hydroxy-isobutyrate |
| US7858350B2 (en) | 2008-09-10 | 2010-12-28 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol |
| US8354563B2 (en) * | 2008-10-16 | 2013-01-15 | Maverick Biofuels, Inc. | Methods and apparatus for synthesis of alcohols from syngas |
| US20100184173A1 (en) | 2008-11-14 | 2010-07-22 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
| CN103396978A (zh) * | 2008-12-12 | 2013-11-20 | 麦特波力克斯公司 | 用于制备聚(5-羟基戊酸)和5碳化合物的绿色工艺和组合物 |
| EP2373781A4 (en) | 2008-12-16 | 2012-10-10 | Genomatica Inc | MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS |
| BRPI1013505A2 (pt) | 2009-04-30 | 2018-02-14 | Genomatica Inc | organismos para a produção de isopropanol, n-butanol, e isobutanol |
| EP4321615A3 (en) | 2009-04-30 | 2024-02-21 | Genomatica, Inc. | Organisms for the production of 1,3-butanediol |
| DK2427544T3 (da) | 2009-05-07 | 2019-10-07 | Genomatica Inc | Mikroorganismer og fremgangsmåder til biosyntese af adipat, hexamethylendiamin og 6-aminokapronsyre |
| BRPI1012877A2 (pt) | 2009-05-15 | 2016-04-05 | Genomatica Inc | organismo para produção de ciclohexanona |
| WO2010141920A2 (en) | 2009-06-04 | 2010-12-09 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol and related methods |
| SI3199511T1 (sl) | 2009-06-04 | 2020-07-31 | Genomatica, Inc. | Proces separacije komponent fermentacijske brozge |
| EP2440669A4 (en) | 2009-06-10 | 2013-08-28 | Genomatica Inc | MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL |
| EP2933338A3 (en) | 2009-09-09 | 2016-01-06 | Genomatica, Inc. | Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids |
| US8377666B2 (en) | 2009-10-13 | 2013-02-19 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto |
| KR20180014240A (ko) | 2009-10-23 | 2018-02-07 | 게노마티카 인코포레이티드 | 아닐린의 제조를 위한 미생물 |
| US8530210B2 (en) | 2009-11-25 | 2013-09-10 | Genomatica, Inc. | Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone |
| US8268607B2 (en) * | 2009-12-10 | 2012-09-18 | Genomatica, Inc. | Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol |
| EP2529011A4 (en) | 2010-01-29 | 2015-07-15 | Genomatica Inc | MICROORGANISMS AND METHODS FOR BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE |
| US8637286B2 (en) | 2010-02-23 | 2014-01-28 | Genomatica, Inc. | Methods for increasing product yields |
| US8048661B2 (en) | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
| KR20130093481A (ko) | 2010-04-13 | 2013-08-22 | 게노마티카 인코포레이티드 | 에틸렌 글리콜을 생산하기 위한 미생물 및 방법 |
| US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
| KR101814648B1 (ko) | 2010-05-05 | 2018-01-04 | 게노마티카 인코포레이티드 | 부타디엔을 생합성하기 위한 미생물 및 방법 |
| BR112013001635A2 (pt) | 2010-07-26 | 2016-05-24 | Genomatica Inc | micro-organismo e métodos para a biossíntese de aromáticos, 2, 4-pentadienoato e 1,3-butadieno |
| WO2012082978A1 (en) | 2010-12-17 | 2012-06-21 | Genomatica, Inc. | Microorganisms and methods for the production of 1.4- cyclohexanedimethanol |
| WO2012106516A1 (en) | 2011-02-02 | 2012-08-09 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of butadiene |
-
2009
- 2009-07-15 EP EP09833782A patent/EP2373781A4/en not_active Withdrawn
- 2009-07-15 JP JP2011542150A patent/JP2012511928A/ja active Pending
- 2009-07-15 AU AU2009327490A patent/AU2009327490A1/en not_active Abandoned
- 2009-07-15 BR BRPI0922276-6A patent/BRPI0922276A2/pt not_active IP Right Cessation
- 2009-07-15 CA CA2746952A patent/CA2746952A1/en not_active Abandoned
- 2009-07-15 CN CN2009801561477A patent/CN102307986A/zh active Pending
- 2009-07-15 KR KR1020117016363A patent/KR20110097951A/ko not_active Withdrawn
- 2009-07-15 WO PCT/US2009/050757 patent/WO2010071697A1/en not_active Ceased
- 2009-12-16 US US12/639,977 patent/US8129155B2/en not_active Expired - Fee Related
-
2011
- 2011-06-15 ZA ZA2011/04462A patent/ZA201104462B/en unknown
-
2012
- 2012-02-10 US US13/371,278 patent/US8470566B2/en active Active
-
2013
- 2013-06-18 US US13/920,927 patent/US9109236B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012511928A5 (https=) | ||
| JP2011509691A5 (https=) | ||
| US8470566B2 (en) | Microorganisms and methods for conversion of syngas and other carbon sources to useful products | |
| ES2702621T3 (es) | Microorganismos recombinantes y sus usos | |
| Yu et al. | Metabolic engineering of Clostridium tyrobutyricum for n-butanol production | |
| Lehmann et al. | Switching Clostridium acetobutylicum to an ethanol producer by disruption of the butyrate/butanol fermentative pathway | |
| Lee et al. | Metabolic engineering of Clostridium acetobutylicum M5 for highly selective butanol production | |
| US9284581B2 (en) | Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol | |
| Jiang et al. | Disruption of the acetoacetate decarboxylase gene in solvent-producing Clostridium acetobutylicum increases the butanol ratio | |
| CA2712779C (en) | Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol | |
| US20100184173A1 (en) | Microorganisms for the production of methyl ethyl ketone and 2-butanol | |
| JP2012525156A (ja) | イソプロパノール、n−ブタノール、及びイソブタノールの産生のための微生物 | |
| JP2012529267A5 (https=) | ||
| KR20080070807A (ko) | Butyryl-CoA를 중간체로 하여 부탄올을 생합성하는 능력을가지는 박테리아를 이용하여 부탄올을 제조하는 방법 | |
| KR100971792B1 (ko) | Butyryl-CoA를 중간체로 하여 부탄올을 생합성하는 능력을가지는 효모를 이용하여 부탄올을 제조하는 방법 | |
| CN118251496A (zh) | 用于高碳和高能效下燃料和化学品生产的羧酸平台 | |
| CN108359628B (zh) | 利用乙酸和丙酸生产聚羟基脂肪酸酯的基因工程菌及其构建方法和应用 | |
| Zhang et al. | Increasing isobutanol yield by double-gene deletion of PDC6 and LPD1 in Saccharomyces cerevisiae | |
| Panchasara et al. | Biosynthetic pathway for production of renewable biofuels | |
| KR101284015B1 (ko) | 부탄올 또는 혼합알코올 생성능 및 아세톤 제거능이 증가된 재조합 변이 미생물 및 이를 이용한 부탄올 또는 혼합 알코올의 제조방법 | |
| US20150024447A1 (en) | Butyraldehyde dehydrogenase mutant, polynucleotide encoding the mutant, vector and microorganism having the polynucleotide, and method of producing 1,4-butanediol using the same | |
| Chauhan et al. | Engineered microbial Systems for the Production of fuels and industrially important chemicals | |
| Kang et al. | Development of hyper acetate producing acetogen from carbon monoxide utilization | |
| AU2013202621A1 (en) | Organisms for the production of isopropanol, n-butanol, and isobutanol |