JP2012509891A - 肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤 - Google Patents

肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤 Download PDF

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JP2012509891A
JP2012509891A JP2011537689A JP2011537689A JP2012509891A JP 2012509891 A JP2012509891 A JP 2012509891A JP 2011537689 A JP2011537689 A JP 2011537689A JP 2011537689 A JP2011537689 A JP 2011537689A JP 2012509891 A JP2012509891 A JP 2012509891A
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グリーン，ハワード，イー．
エー． ヤング，アンドリュー
ゲドリン，ブロニスラヴァ
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サティオゲン ファーマシューティカルズ，インク．
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JP2011537689A 2008-11-26 2009-11-23 肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤 Pending JP2012509891A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US11835608P 2008-11-26 2008-11-26
US61/118,356 2008-11-26
US23963609P 2009-09-03 2009-09-03
US23965709P 2009-09-03 2009-09-03
US23966309P 2009-09-03 2009-09-03
US61/239,636 2009-09-03
US61/239,663 2009-09-03
US61/239,657 2009-09-03
US25520509P 2009-10-27 2009-10-27
US61/255,205 2009-10-27
PCT/US2009/065577 WO2010062861A2 (en) 2008-11-26 2009-11-23 Bile acid recycling inhibitors for treatment of obesity and diabetes

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JP2014047622A Division JP6154766B2 (ja) 2008-11-26 2014-03-11 肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤

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JP2012509891A true JP2012509891A (ja) 2012-04-26
JP2012509891A5 JP2012509891A5 (https=) 2013-04-04

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JP2011537689A Pending JP2012509891A (ja) 2008-11-26 2009-11-23 肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤
JP2014047622A Expired - Fee Related JP6154766B2 (ja) 2008-11-26 2014-03-11 肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤
JP2016005402A Pending JP2016155800A (ja) 2008-11-26 2016-01-14 肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤

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JP2016005402A Pending JP2016155800A (ja) 2008-11-26 2016-01-14 肥満症及び糖尿病を治療するための胆汁酸再循環阻害剤

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US (3) US9339480B2 (https=)
EP (1) EP2367554A4 (https=)
JP (3) JP2012509891A (https=)
CN (1) CN102316872B (https=)
CA (1) CA2744817C (https=)
GB (1) GB2465879B (https=)
WO (1) WO2010062861A2 (https=)

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WO2010062861A2 (en) 2008-11-26 2010-06-03 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of obesity and diabetes
US9006288B2 (en) 2009-01-12 2015-04-14 Biokier, Inc. Composition and method for treatment of diabetes
US9314444B2 (en) 2009-01-12 2016-04-19 Biokier, Inc. Composition and method for treatment of NASH
KR20110120866A (ko) 2009-01-12 2011-11-04 바이오키어 인코포레이티드 당뇨병 치료 조성물 및 치료방법
US9301938B2 (en) 2009-09-23 2016-04-05 Biokier, Inc. Composition and method for treatment of diabetes
CN102781922A (zh) * 2009-12-11 2012-11-14 埃克塞利希斯股份有限公司 Tgr5激动剂
US20130273154A1 (en) * 2011-03-02 2013-10-17 Joseph M. Fayad Oral formulations Mimetic of Roux-en-Y gastric bypass actions on the ileal brake; Compositions, Methods of Treatment, Diagnostics and Systems for treatment of metabolic syndrome manifestations including insulin resistance, fatty liver disease, hpperlipidemia, and type 2 diabetes
JO3131B1 (ar) * 2010-04-27 2017-09-20 Glaxosmithkline Llc مركبات كيميائية
ES2552657T3 (es) 2010-05-26 2015-12-01 Satiogen Pharmaceuticals, Inc. Inhibidores del reciclado de ácidos biliares y saciógenos para el tratamiento de diabetes, obesidad, y afecciones gastrointestinales inflamatorias
ES2687027T3 (es) 2010-11-04 2018-10-23 Albireo Ab Inhibidores de ibat para el tratamiento de enfermedades hepáticas
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JPN6013016571; ＧＥＹＥＲ，　Ｊ．　ｅｔ　ａｌ: 'Ｔｈｅ　ｓｏｌｕｔｅ　ｃａｒｒｉｅｒ　ｆａｍｉｌｙ　ＳＬＣ１０：　Ｍｏｒｅ　ｔｈａｎ　ａ　ｆａｍｉｌｙ　ｏｆ　ｂｉｌｅ　ａｃｉｄ　ｔｒａｎｓｐｏｒｔｅｒｓ　ｒｅｇａｒｄｉｎｇ　ｆｕｎｃｔｉｏｎ　ａｎｄ' Ｎａｕｎｙｎ-Ｓｃｈｍｉｅｄｅｂｅｒｇ'ｓ　Ａｒｃｈｉｖｅｓ　ｏｆ　Ｐｈａｒｍａｃｏｌｏｇｙ Ｖｏｌ．３７２，　Ｎｏ．６, 2006, ｐ．４１３-４３１ *
JPN6013016573; ＢＲＩＮＴＯＮ，Ｅ．Ａ．: 'Ｎｏｖｅｌ　ｐａｔｈｗａｙｓ　ｆｏｒ　ｇｌｙｃａｅｍｉｃ　ｃｏｎｔｒｏｌ　ｉｎ　ｔｙｐｅ　２　ｄｉａｂｅｔｅｓ：　ｆｏｃｕｓ　ｏｎ　ｂｉｌｅ　ａｃｉｄ　ｍｏｄｕｌａｔｉｏｎ' Ｄｉａｂｅｔｅｓ，　Ｏｂｅｓｉｔｙ　ａｎｄ　Ｍｅｔａｂｏｌｉｓｍ Ｖｏｌ．１０，　Ｎｏ．１１, 200805, ｐ．１００４-１０１１ *
JPN7013001316; ＫＲＡＭＥＲ，　Ｗ．　ｅｔ　ａｌ: 'Ｂｉｌｅ　Ａｃｉｄ　Ｒｅａｂｓｏｒｐｔｉｏｎ　Ｉｎｈｉｂｉｔｏｒｓ（ＢＡＲＩ）：Ｎｏｖｅｌ　Ｈｙｐｏｌｉｐｉｄｅｃｉｍ　Ｄｒｕｇｓ' Ｃｕｒｒｅｎｔ　Ｍｅｄｉｃｉｎａｌ　Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１３，　Ｎｏ．９, 2006, ｐ．９９７-１０１６ *
JPN7013001317; ＨＵＡＮＧ，　Ｈ．-Ｃ．　ｅｔ　ａｌ: 'Ｄｉｓｃｏｖｅｒｙ　ｏｆ　Ｐｏｔｅｎｔ，ｎｏｎｓｙｓｔｅｍｉｃ　ａｐｉｃａｌ　ｓｏｄｉｕｍ-ｃｏｄｅｐｅｎｄｅｎｔ　ｂｉｌｅ　ａｃｉｄ　ｔｒａｎｓｐｏｒｔｅｒ　ｉｎｈｉｂｉｔｏｒｓ（Ｐａｒｔ２）' Ｊ．Ｍｅｄ．Ｃｈｅｍ． Ｖｏｌ．４８，　Ｎｏ．１８, 2005, ｐ．５８５３-５８６８ *
JPN7013001318; ＬＥＥ，　Ａ．　ｅｔ　ａｌ: 'Ｍｅｔｆｏｒｍｉｎ　Ｄｅｃｒｅａｓｅｓ　Ｆｏｏｄ　ｃｏｎｓｕｍｐｔｉｏｎ　ａｎｄ　Ｉｎｄｕｃｅｓ　Ｗｅｉｇｈｔ　Ｌｏｓｓ　ｉｎ　Ｓｕｂｊｅｃｔｓ　ｗｉｔｈ　Ｏｂｅｓｉｔｙ　ｗｉｔｈ　Ｔｙｐｅ　ＩＩ　Ｎ' Ｏｂｅｓｉｔｙ　Ｒｅｓｅａｒｃｈ Ｖｏｌ．６，　Ｎｏ．１, 1998, ｐ．４７-５３ *

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US20120157399A1 (en) 2012-06-21
US20100130472A1 (en) 2010-05-27
CA2744817C (en) 2020-07-07
CN102316872B (zh) 2016-12-21
GB2465879B (en) 2013-02-13
EP2367554A2 (en) 2011-09-28
GB0920704D0 (en) 2010-01-13
JP6154766B2 (ja) 2017-06-28
JP2014144961A (ja) 2014-08-14
US20160220577A1 (en) 2016-08-04
CA2744817A1 (en) 2010-06-03
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