JP2012507562A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012507562A5 JP2012507562A5 JP2011534806A JP2011534806A JP2012507562A5 JP 2012507562 A5 JP2012507562 A5 JP 2012507562A5 JP 2011534806 A JP2011534806 A JP 2011534806A JP 2011534806 A JP2011534806 A JP 2011534806A JP 2012507562 A5 JP2012507562 A5 JP 2012507562A5
- Authority
- JP
- Japan
- Prior art keywords
- particles
- base polymer
- spacer material
- solution
- microsphere
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- 229920005601 base polymer Polymers 0.000 claims 7
- 239000000463 material Substances 0.000 claims 6
- 125000006850 spacer group Chemical group 0.000 claims 6
- 230000002051 biphasic effect Effects 0.000 claims 5
- 239000011148 porous material Substances 0.000 claims 5
- 239000000654 additive Substances 0.000 claims 4
- 230000000996 additive effect Effects 0.000 claims 4
- 239000004005 microsphere Substances 0.000 claims 4
- 238000010791 quenching Methods 0.000 claims 4
- 230000000171 quenching effect Effects 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 125000002877 alkyl aryl group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 229920003169 water-soluble polymer Polymers 0.000 claims 2
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- 238000010669 acid-base reaction Methods 0.000 claims 1
- 229910001508 alkali metal halide Inorganic materials 0.000 claims 1
- 150000001340 alkali metals Chemical class 0.000 claims 1
- 229910001615 alkaline earth metal halide Inorganic materials 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 claims 1
- 229960004316 cisplatin Drugs 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000005484 gravity Effects 0.000 claims 1
- 239000012456 homogeneous solution Substances 0.000 claims 1
- 239000007972 injectable composition Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000007873 sieving Methods 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000012798 spherical particle Substances 0.000 claims 1
- 238000003860 storage Methods 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19780308P | 2008-10-30 | 2008-10-30 | |
| US61/197,803 | 2008-10-30 | ||
| PCT/US2009/062744 WO2010062678A2 (en) | 2008-10-30 | 2009-10-30 | Micro-spherical porous biocompatible scaffolds and methods and apparatus for fabricating same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012507562A JP2012507562A (ja) | 2012-03-29 |
| JP2012507562A5 true JP2012507562A5 (cg-RX-API-DMAC7.html) | 2012-12-13 |
Family
ID=42026232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011534806A Pending JP2012507562A (ja) | 2008-10-30 | 2009-10-30 | 微小球性多孔質生体適合性足場並びにその製造方法及び装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20110212179A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2344578A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2012507562A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102143996A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010062678A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6660301B1 (en) | 1998-03-06 | 2003-12-09 | Biosphere Medical, Inc. | Injectable microspheres for dermal augmentation and tissue bulking |
| US7338657B2 (en) | 2001-03-15 | 2008-03-04 | Biosphere Medical, Inc. | Injectable microspheres for tissue construction |
| US6436424B1 (en) | 2000-03-20 | 2002-08-20 | Biosphere Medical, Inc. | Injectable and swellable microspheres for dermal augmentation |
| AU2001249221A1 (en) | 2000-03-20 | 2001-10-03 | Biosphere Medical, Inc. | Injectable and swellable microspheres for tissue bulking |
| EP1820495B1 (en) | 2000-03-24 | 2017-03-01 | Biosphere Medical, Inc. | Microspheres for active embolization |
| BRPI0608766A8 (pt) | 2005-05-09 | 2018-04-17 | Biosphere Medical Sa | microsfera substancialmente esférica, composição, e, métodos para administração de medicamento e para embolização ativa em um mamífero |
| US20080033366A1 (en) | 2006-01-30 | 2008-02-07 | Surgica Corporation | Compressible intravascular embolization particles and related methods and delivery systems |
| KR102334602B1 (ko) | 2013-08-09 | 2021-12-06 | 킴벌리-클라크 월드와이드, 인크. | 형상 보유 특성을 구비한 연성 중합체 물질 |
| AU2014304190B2 (en) | 2013-08-09 | 2018-02-15 | Kimberly-Clark Worldwide, Inc. | Polymeric material for three-dimensional printing |
| KR102224569B1 (ko) | 2013-08-09 | 2021-03-08 | 킴벌리-클라크 월드와이드, 인크. | 중합체 물질의 다공성을 선택적으로 제어하기 위한 기술 |
| EP3030609B1 (en) * | 2013-08-09 | 2020-09-02 | Kimberly-Clark Worldwide, Inc. | Microparticles having a multimodal pore distribution |
| WO2015019201A1 (en) | 2013-08-09 | 2015-02-12 | Kimberly-Clark Worldwide, Inc. | Anisotropic polymeric material |
| RU2634255C2 (ru) | 2013-08-09 | 2017-10-24 | Кимберли-Кларк Ворлдвайд, Инк. | Система доставки для активных средств |
| WO2015038988A1 (en) | 2013-09-13 | 2015-03-19 | Modern Meadow, Inc. | Edible and animal-product-free microcarriers for engineered meat |
| EP3046952B1 (en) | 2013-09-19 | 2021-05-12 | Terumo Corporation | Polymer particles |
| US9408916B2 (en) | 2013-09-19 | 2016-08-09 | Microvention, Inc. | Polymer films |
| CN103550824B (zh) * | 2013-11-01 | 2016-03-02 | 南京医科大学附属口腔医院 | 一种引导骨组织再生的支架的制备方法 |
| AU2014346486B2 (en) | 2013-11-08 | 2016-12-08 | Terumo Corporation | Polymer particles |
| JP2015112262A (ja) * | 2013-12-11 | 2015-06-22 | 学校法人藤田学園 | 組織修復及び/又は再生促進材 |
| CA2938156C (en) | 2014-02-05 | 2022-05-10 | Modern Meadow, Inc. | Dried food products formed from cultured muscle cells |
| US20160220498A1 (en) * | 2015-01-29 | 2016-08-04 | Aneesh SONI | Fully or partially biodegradable device for controlled drug delivery |
| CA2975301C (en) | 2015-02-09 | 2025-02-04 | Slingshot Biosciences, Inc. | Hydrogel particles exhibiting tunable optical characteristics and methods of use |
| WO2016154592A1 (en) | 2015-03-26 | 2016-09-29 | Microvention, Inc. | Embiolic particles |
| US10858491B2 (en) | 2015-08-10 | 2020-12-08 | Kyoto University | Porous particle made of organic polymer, method for producing porous particle made of organic polymer, and block copolymer |
| JP6644215B2 (ja) * | 2015-08-10 | 2020-02-12 | 国立大学法人京都大学 | 多孔性粒子、多孔性粒子の製造方法およびブロックコポリマー |
| ES2842501T5 (es) | 2015-09-21 | 2023-04-13 | Modern Meadow Inc | Materiales compuestos de tejido reforzados con fibras |
| CN105175772A (zh) * | 2015-10-22 | 2015-12-23 | 山西科瑞迪生物科技有限公司 | 多肽/核苷酸合成用固相载体材料易官能化活性树脂的制备方法 |
| CN105327405B (zh) * | 2015-10-23 | 2019-01-29 | 华南理工大学 | 用于治疗宫颈炎的载药支架及其制备方法 |
| US11542374B2 (en) | 2016-02-15 | 2023-01-03 | Modern Meadow, Inc. | Composite biofabricated material |
| US10806805B2 (en) | 2016-03-03 | 2020-10-20 | Amrita Vishwa Vidyapeetham | MRI and CT contrast-enabled composite implants for image-guided tissue regeneration and therapy |
| EP3423102B1 (en) * | 2016-03-31 | 2022-09-07 | Immutrix Therapeutics, Inc. | Composition for use in the treatment of preeclampsia |
| WO2017184768A1 (en) | 2016-04-19 | 2017-10-26 | The Broad Institute Inc. | Novel crispr enzymes and systems |
| US11286478B2 (en) | 2016-04-19 | 2022-03-29 | The Broad Institute, Inc. | Cpf1 complexes with reduced indel activity |
| CA3026110A1 (en) | 2016-04-19 | 2017-11-02 | The Broad Institute, Inc. | Novel crispr enzymes and systems |
| CN107304251A (zh) * | 2016-04-22 | 2017-10-31 | 中国石油化工股份有限公司 | 用于选择性激光烧结的聚丙烯粉末及其制备 |
| US12421369B2 (en) * | 2016-06-14 | 2025-09-23 | The Regents Of The University Of California | Porous polymer scaffolds, and methods of making and using the same |
| US20200283743A1 (en) | 2016-08-17 | 2020-09-10 | The Broad Institute, Inc. | Novel crispr enzymes and systems |
| US11352647B2 (en) | 2016-08-17 | 2022-06-07 | The Broad Institute, Inc. | Crispr enzymes and systems |
| KR102162370B1 (ko) | 2016-09-28 | 2020-10-06 | 테루모 가부시키가이샤 | 중합체 입자 |
| WO2018144241A1 (en) | 2017-01-31 | 2018-08-09 | Kimberly-Clark Worldwide, Inc. | Porous polyester material |
| JP6925014B2 (ja) * | 2017-02-15 | 2021-08-25 | ドリームメディカルパートナーズ株式会社 | 塞栓材の製造方法 |
| US11577062B2 (en) | 2017-04-11 | 2023-02-14 | University Of Florida Research Foundation, Inc. | Systems and methods for in-situ, bottom-up tissue generation |
| WO2018191750A2 (en) | 2017-04-14 | 2018-10-18 | The Broad Institute Inc. | Novel delivery of large payloads |
| WO2019135816A2 (en) | 2017-10-23 | 2019-07-11 | The Broad Institute, Inc. | Novel nucleic acid modifiers |
| WO2019094984A1 (en) | 2017-11-13 | 2019-05-16 | The Broad Institute, Inc. | Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells |
| AU2018253595A1 (en) | 2017-11-13 | 2019-05-30 | Modern Meadow, Inc. | Biofabricated leather articles having zonal properties |
| WO2019094983A1 (en) | 2017-11-13 | 2019-05-16 | The Broad Institute, Inc. | Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway |
| US11590080B2 (en) | 2017-12-18 | 2023-02-28 | C.R. Bard, Inc. | Drug-loaded biodegradable microbead compositions including drug-containing vesicular agents |
| EP4000604B1 (en) | 2017-12-18 | 2023-08-23 | C. R. Bard, Inc. | Drug-loaded microbead compositions, embolization compositions and associated methods |
| CN108126239B (zh) * | 2018-01-02 | 2020-11-10 | 四川大学 | 一种孔道结构可控的明胶细胞支架及其制备方法 |
| CN109106986B (zh) * | 2018-09-14 | 2020-12-25 | 广州润虹医药科技股份有限公司 | 一种药物控释磷酸钙骨水泥复合微球、其制备方法及应用 |
| MX2021008462A (es) | 2019-01-17 | 2021-08-19 | Modern Meadow Inc | Materiales de colageno estratificados y metodos para fabricarlos. |
| CN109833509B (zh) * | 2019-01-18 | 2021-10-15 | 太阳雨林(厦门)生物医药有限公司 | 一种多重缓释血管栓塞载药组合物 |
| US12215382B2 (en) | 2019-03-01 | 2025-02-04 | The General Hospital Corporation | Liver protective MARC variants and uses thereof |
| US20220177863A1 (en) | 2019-03-18 | 2022-06-09 | The Broad Institute, Inc. | Type vii crispr proteins and systems |
| WO2020236972A2 (en) | 2019-05-20 | 2020-11-26 | The Broad Institute, Inc. | Non-class i multi-component nucleic acid targeting systems |
| US12297426B2 (en) | 2019-10-01 | 2025-05-13 | The Broad Institute, Inc. | DNA damage response signature guided rational design of CRISPR-based systems and therapies |
| CN115443142A (zh) * | 2020-02-10 | 2022-12-06 | 优美佳生物技术有限公司 | 胰岛移植装置、套件和方法 |
| US20210299309A1 (en) * | 2020-03-31 | 2021-09-30 | Parasol Medical, Llc | Tent with antimicrobial treatment applied thereto and method of imparting antimicrobial properties to the tent |
| WO2021206440A1 (ko) * | 2020-04-09 | 2021-10-14 | 주식회사 피엘마이크로메드 | 색전 시술용 마이크로 비드 및 증식성 질환 치료용 조성물 |
| CN112890882A (zh) * | 2021-01-27 | 2021-06-04 | 广州跃金科技有限公司 | 一种注射装置及硅胶填充设备 |
| KR20240116721A (ko) | 2021-10-29 | 2024-07-30 | 슬링샷 바이오사이언시즈 인코포레이티드 | 피더 세포 및 합성 항원 제시 세포로서의 하이드로겔 입자 |
| CN114191410A (zh) * | 2021-11-15 | 2022-03-18 | 深圳北航新兴产业技术研究院 | 一种诊疗一体化双亲微球缓释微球的制备方法 |
| CN114470308A (zh) * | 2022-03-01 | 2022-05-13 | 苏州森康微球医疗科技有限公司 | 一种大孔聚丙烯酸钠栓塞微球的制备工艺 |
| CN119562762A (zh) | 2022-04-04 | 2025-03-04 | 加利福尼亚大学董事会 | 遗传互补组合物和方法 |
| JP2025516304A (ja) | 2022-05-05 | 2025-05-27 | スリングショット バイオサイエンシーズ, インコーポレイテッド | 血液学のための赤血球模倣物としての作出された粒子およびそれらを含有する組成物 |
| CN114949348B (zh) * | 2022-06-30 | 2023-09-29 | 成都世联康健生物科技有限公司 | 藻酸盐-载hDPSCs的GelMA纤维微球及其制备方法 |
| WO2024092161A2 (en) * | 2022-10-26 | 2024-05-02 | Slingshot Biosciences, Inc. | Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation |
| WO2025072383A1 (en) | 2023-09-25 | 2025-04-03 | The Broad Institute, Inc. | Viral open reading frames, uses thereof, and methods of detecting the same |
| CN117018298B (zh) * | 2023-10-09 | 2023-12-26 | 北京华龛生物科技有限公司 | 一种降解时间可控的可注射多孔微球及其制备方法和应用 |
| WO2025097055A2 (en) | 2023-11-02 | 2025-05-08 | The Broad Institute, Inc. | Compositions and methods of use of t cells in immunotherapy |
| WO2025129158A1 (en) | 2023-12-15 | 2025-06-19 | The Broad Institute, Inc. | Engineered arc delivery vesicles and uses thereof |
| TW202525349A (zh) * | 2023-12-28 | 2025-07-01 | 白金科技股份有限公司 | 微球及其製備方法 |
| CN118406273B (zh) * | 2024-05-29 | 2024-11-19 | 广东安拓普聚合物科技股份有限公司 | 一种医用导管用tpu材料及其生产工艺 |
| WO2025250808A1 (en) | 2024-05-29 | 2025-12-04 | The Brigham And Women’S Hospital, Inc. | Anti-crispr delivery compositions and methods |
Family Cites Families (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3673125A (en) * | 1969-05-10 | 1972-06-27 | Kanegafuchi Spinning Co Ltd | Method of producing polyvinyl acetal porous articles |
| GB1381258A (en) * | 1970-12-11 | 1975-01-22 | Porvair Ltd | Water vapour permeable materials |
| US3919411A (en) * | 1972-01-31 | 1975-11-11 | Bayvet Corp | Injectable adjuvant and compositions including such adjuvant |
| CA1134977A (en) * | 1978-09-07 | 1982-11-02 | Sumitomo Chemical Co., Ltd. | Method for preparing highly absorbent polymers |
| US4314032A (en) * | 1978-10-26 | 1982-02-02 | Kureha Kagaku Kogyo Kabushiki Kaisha | Crosslinked polyvinyl alcohol gel |
| US4268495A (en) * | 1979-01-08 | 1981-05-19 | Ethicon, Inc. | Injectable embolization and occlusion solution |
| US4306031A (en) * | 1979-08-14 | 1981-12-15 | Mitsubishi Chemical Industries Limited | Weakly acidic cation exchange resin and process for producing same |
| GB2088392B (en) * | 1980-12-03 | 1984-05-02 | Sumitomo Chemical Co | Production of hydrogels |
| CA1225585A (en) * | 1983-06-30 | 1987-08-18 | Maria T. Litvinova | Composition for embolization of blood vessels |
| GB8418772D0 (en) * | 1984-07-24 | 1984-08-30 | Geistlich Soehne Ag | Chemical substances |
| US4680171A (en) * | 1985-03-15 | 1987-07-14 | William Shell | Visualization of a bloodstream circulation with biodegradable microspheres |
| US5186922A (en) * | 1985-03-15 | 1993-02-16 | See/Shell Biotechnology, Inc. | Use of biodegradable microspheres labeled with imaging energy constrast materials |
| US4803075A (en) * | 1986-06-25 | 1989-02-07 | Collagen Corporation | Injectable implant composition having improved intrudability |
| JPS6317904A (ja) * | 1986-07-09 | 1988-01-25 | Mitsubishi Chem Ind Ltd | 多孔質架橋ポリビニルアルコ−ル粒子の製造法 |
| CA1329800C (en) * | 1987-12-29 | 1994-05-24 | Hiroaki Takayanagi | Composite separating agent |
| JPH064713B2 (ja) * | 1988-07-22 | 1994-01-19 | テルモ株式会社 | 生体適合性材料 |
| JPH0286838A (ja) * | 1988-09-22 | 1990-03-27 | Terumo Corp | 水不溶性ヒドロゲルおよびその製造方法 |
| US5510418A (en) * | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
| US5162430A (en) * | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
| US5258028A (en) * | 1988-12-12 | 1993-11-02 | Ersek Robert A | Textured micro implants |
| US5092883A (en) * | 1988-12-28 | 1992-03-03 | Eppley Barry L | Method for promoting soft connective tissue growth and repair in mammals |
| CA2017570C (en) * | 1989-05-31 | 2000-12-19 | James R. Gross | Porous structure of an absorbent polymer |
| US5007940A (en) * | 1989-06-09 | 1991-04-16 | American Medical Systems, Inc. | Injectable polymeric bodies |
| JPH0436328A (ja) * | 1990-06-01 | 1992-02-06 | Chuichi Hirayama | 大孔径ポリアミノ酸多孔質球状粒子とその製造方法 |
| DE69114782T2 (de) * | 1990-08-08 | 1996-04-18 | Takeda Chemical Industries Ltd | Intravaskulär embolisierendes Mittel mit Gehalt an einem die Angiogenesis hemmenden Stoff. |
| US5410016A (en) * | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
| FR2676927B1 (fr) * | 1991-05-29 | 1995-06-23 | Ibf | Microspheres utilisables pour les occlusions vasculaires therapeutiques et solutions injectables les contenant. |
| US5554658A (en) * | 1991-08-06 | 1996-09-10 | Rosenblatt; Solomon | Injection molded PVA Sponge |
| JP3356447B2 (ja) * | 1991-10-16 | 2002-12-16 | テルモ株式会社 | 乾燥高分子ゲルからなる血管病変塞栓材料 |
| JP3011768B2 (ja) * | 1992-02-28 | 2000-02-21 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | 組織接触材料および制御放出キャリアとしての光重合性生分解性親水ゲル |
| JPH05294839A (ja) * | 1992-04-20 | 1993-11-09 | Biomaterial Universe Kk | シスプラチン含有生体内分解吸収性高分子の微小球お よびその製造法 |
| US5629327A (en) * | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
| ATE163230T1 (de) * | 1993-03-09 | 1998-02-15 | Epic Therapeutics Inc | Makromolekulare mikropartikel und verfahren zu ihrer herstellung |
| US5583162A (en) * | 1994-06-06 | 1996-12-10 | Biopore Corporation | Polymeric microbeads and method of preparation |
| UA10911C2 (uk) * | 1994-08-10 | 1996-12-25 | Мале Впроваджувальне Підприємство "Іhтерфалл" | Біосумісhий гідрогель |
| US5955108A (en) * | 1994-12-16 | 1999-09-21 | Quadrant Healthcare (Uk) Limited | Cross-linked microparticles and their use as therapeutic vehicles |
| WO1996022736A1 (en) * | 1995-01-27 | 1996-08-01 | Scimed Life Systems, Inc. | Embolizing system |
| US5752974A (en) * | 1995-12-18 | 1998-05-19 | Collagen Corporation | Injectable or implantable biomaterials for filling or blocking lumens and voids of the body |
| DE19601699A1 (de) * | 1996-01-18 | 1997-07-24 | Wacker Chemie Gmbh | Redispergierbare Polymerisatpulver und daraus erhältliche wäßrige Polymerisat-Dispersionen |
| US5785977A (en) * | 1996-02-07 | 1998-07-28 | Breithbarth; Richard | Non-metallic microparticle carrier materials |
| US5611344A (en) * | 1996-03-05 | 1997-03-18 | Acusphere, Inc. | Microencapsulated fluorinated gases for use as imaging agents |
| BR9708355A (pt) * | 1996-03-27 | 1999-08-03 | Novartis Ag | Processo para produção de um polímero poroso através do uso de um porogénio |
| US5823198A (en) * | 1996-07-31 | 1998-10-20 | Micro Therapeutics, Inc. | Method and apparatus for intravasculer embolization |
| US5925683A (en) * | 1996-10-17 | 1999-07-20 | Target Therapeutics, Inc. | Liquid embolic agents |
| US6048908A (en) * | 1997-06-27 | 2000-04-11 | Biopore Corporation | Hydrophilic polymeric material |
| US5989463A (en) * | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6565885B1 (en) * | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US6660301B1 (en) * | 1998-03-06 | 2003-12-09 | Biosphere Medical, Inc. | Injectable microspheres for dermal augmentation and tissue bulking |
| WO1999044643A1 (en) * | 1998-03-06 | 1999-09-10 | Biosepra Medical Inc. | Implantable particles for tissue bulking and the treatment of gastroesophageal reflux disease, urinary incontinence, and skin wrinkles |
| US5891470A (en) * | 1998-04-17 | 1999-04-06 | Advanced Polymer Systems, Inc. | Softgel formulation containing retinol |
| US6165193A (en) * | 1998-07-06 | 2000-12-26 | Microvention, Inc. | Vascular embolization with an expansible implant |
| FR2784580B1 (fr) * | 1998-10-16 | 2004-06-25 | Biosepra Inc | Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci |
| US6103255A (en) * | 1999-04-16 | 2000-08-15 | Rutgers, The State University | Porous polymer scaffolds for tissue engineering |
| JP2002541925A (ja) * | 1999-04-16 | 2002-12-10 | ラトガーズ,ザ ステイト ユニバーシティ | 組織工学用多孔質ポリマー足場 |
| US6710126B1 (en) * | 1999-11-15 | 2004-03-23 | Bio Cure, Inc. | Degradable poly(vinyl alcohol) hydrogels |
| KR100335866B1 (ko) * | 2000-01-06 | 2002-05-10 | 박호군 | 폴리아세트산비닐 코어/폴리비닐알코올 외피의 2중 구조를갖는 미세구형 색전재료 및 그의 제조방법 |
| ATE373682T1 (de) * | 2000-03-13 | 2007-10-15 | Biocure Inc | Embolische zusammensetzungen |
| US6652883B2 (en) * | 2000-03-13 | 2003-11-25 | Biocure, Inc. | Tissue bulking and coating compositions |
| US7338657B2 (en) * | 2001-03-15 | 2008-03-04 | Biosphere Medical, Inc. | Injectable microspheres for tissue construction |
| US6436424B1 (en) * | 2000-03-20 | 2002-08-20 | Biosphere Medical, Inc. | Injectable and swellable microspheres for dermal augmentation |
| AU2001249221A1 (en) * | 2000-03-20 | 2001-10-03 | Biosphere Medical, Inc. | Injectable and swellable microspheres for tissue bulking |
| EP1820495B1 (en) * | 2000-03-24 | 2017-03-01 | Biosphere Medical, Inc. | Microspheres for active embolization |
| US20030212022A1 (en) * | 2001-03-23 | 2003-11-13 | Jean-Marie Vogel | Compositions and methods for gene therapy |
| CA2436418A1 (en) * | 2001-01-30 | 2002-08-08 | Board Of Regents, The University Of Texas Systems | Process for production of nanoparticles and microparticles by spray freezing into liquid |
| US6537569B2 (en) * | 2001-02-14 | 2003-03-25 | Microvention, Inc. | Radiation cross-linked hydrogels |
| WO2002100444A1 (en) * | 2001-06-08 | 2002-12-19 | Biosphere Medical Inc. | Colloidal metal labelled microparticles, their production and use |
| US6911219B2 (en) * | 2001-09-27 | 2005-06-28 | Surgica Corporation | Partially acetalized polyvinyl alcohol embolization particles, compositions containing those particles and methods of making and using them |
| US7094369B2 (en) * | 2002-03-29 | 2006-08-22 | Scimed Life Systems, Inc. | Processes for manufacturing polymeric microspheres |
| US7462366B2 (en) * | 2002-03-29 | 2008-12-09 | Boston Scientific Scimed, Inc. | Drug delivery particle |
| DE60329909D1 (de) * | 2002-03-29 | 2009-12-17 | Boston Scient Ltd | Partikel für arzneistoffabgabe |
| US7053134B2 (en) * | 2002-04-04 | 2006-05-30 | Scimed Life Systems, Inc. | Forming a chemically cross-linked particle of a desired shape and diameter |
| US7838699B2 (en) * | 2002-05-08 | 2010-11-23 | Biosphere Medical | Embolization using degradable crosslinked hydrogels |
| US7303575B2 (en) * | 2002-08-01 | 2007-12-04 | Lumen Biomedical, Inc. | Embolism protection devices |
| CA2494959C (en) * | 2002-08-09 | 2011-09-13 | Boston Scientific Limited | Embolization |
| US20040076582A1 (en) * | 2002-08-30 | 2004-04-22 | Dimatteo Kristian | Agent delivery particle |
| US7883490B2 (en) * | 2002-10-23 | 2011-02-08 | Boston Scientific Scimed, Inc. | Mixing and delivery of therapeutic compositions |
| US7588825B2 (en) * | 2002-10-23 | 2009-09-15 | Boston Scientific Scimed, Inc. | Embolic compositions |
| CA2504283A1 (en) * | 2002-10-31 | 2004-05-21 | Umd, Inc. | Therapeutic compositions for drug delivery to and through covering epithelia |
| CA2531894C (en) * | 2003-09-25 | 2014-02-11 | Rutgers, The State University | Inherently radiopaque polymeric products for embolotherapy |
| US7556650B2 (en) * | 2004-06-29 | 2009-07-07 | Spine Wave, Inc. | Methods for injecting a curable biomaterial into an intervertebral space |
| BRPI0608766A8 (pt) * | 2005-05-09 | 2018-04-17 | Biosphere Medical Sa | microsfera substancialmente esférica, composição, e, métodos para administração de medicamento e para embolização ativa em um mamífero |
| WO2007090130A2 (en) * | 2006-01-30 | 2007-08-09 | Surgica Corporation | Porous intravascular embolization particles and related methods |
| US20080033366A1 (en) * | 2006-01-30 | 2008-02-07 | Surgica Corporation | Compressible intravascular embolization particles and related methods and delivery systems |
| US7888410B2 (en) * | 2007-04-24 | 2011-02-15 | Eastman Kodak Company | Method of making porous particles |
| EP2351779B1 (en) * | 2010-01-27 | 2019-04-24 | Biosphere Medical, Inc. | Microspheres and method of making the microspheres |
-
2009
- 2009-10-30 EP EP09745251A patent/EP2344578A2/en not_active Withdrawn
- 2009-10-30 WO PCT/US2009/062744 patent/WO2010062678A2/en not_active Ceased
- 2009-10-30 US US13/126,456 patent/US20110212179A1/en not_active Abandoned
- 2009-10-30 JP JP2011534806A patent/JP2012507562A/ja active Pending
- 2009-10-30 CN CN2009801344899A patent/CN102143996A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012507562A5 (cg-RX-API-DMAC7.html) | ||
| Wu et al. | Selective adsorption of La3+ using a tough alginate-clay-poly (n-isopropylacrylamide) hydrogel with hierarchical pores and reversible re-deswelling/swelling cycles | |
| Nguyen et al. | Drop penetration time in heterogeneous powder beds | |
| Wu et al. | Regulating block copolymer assembly structures in emulsion droplets through metal ion coordination | |
| CN102492250A (zh) | 一种温度敏感聚合物/金纳米粒子杂化微球及其制备方法 | |
| CN104587924B (zh) | 低聚物预涂覆制备低密度无渗透性多孔或中空微球的方法 | |
| CN105457601B (zh) | 一种叶酸修饰的磁性氧化石墨烯吸附剂的制备及应用 | |
| CN103788526B (zh) | 一种载银聚合物微球的制备方法 | |
| Son et al. | In situ functionalization of highly porous polymer microspheres with silver nanoparticles via bio-inspired chemistry | |
| Chen et al. | Bioinspired separator with ion-selective nanochannels for lithium metal batteries | |
| CN114405483A (zh) | 具有核壳结构的多孔纤维素微球吸附剂及制备方法和应用 | |
| KR20160017441A (ko) | 다공성 지지체 및 그 제조방법 | |
| JPWO2019039292A1 (ja) | 微小カプセル又はビーズの製造方法 | |
| Li et al. | One-step asymmetric growth of continuous metal–organic framework thin films on two-dimensional colloidal crystal arrays: A facile approach toward multifunctional superstructures | |
| CN102423298B (zh) | 一种核壳结构胶原多肽螯合钙纳米粒子的制备方法 | |
| CN102772827A (zh) | Plga/羟基磷灰石/碳酸钙复合微球及其制备方法 | |
| Li et al. | Carrier-free, functionalized pure drug nanorods as a novel cancer-targeted drug delivery platform | |
| CN100348179C (zh) | 一种包埋抗癌药物的微胶囊的制备方法 | |
| CN105200666B (zh) | 一种超疏水/超亲油空心微球状pvdf纳米纤维的制备方法 | |
| CN103833102A (zh) | 一种重金属吸附复合膜及其制备方法 | |
| RU2007137062A (ru) | Способ получения гранул из политетрафторэтилена, содержащих наполнитель | |
| ES2585819T3 (es) | Proceso para producir membranas conductoras de protones | |
| EP3013325A2 (en) | Nanoparticle and gelation stabilized functional composites of an ionic salt in a hydrophobic polymer matrix | |
| JP6192639B2 (ja) | 繊維状銅微粒子の製造方法 | |
| JP6909461B2 (ja) | 浮遊系細胞保定用多孔質超薄膜とその製造方法 |