JP2012507270A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012507270A5 JP2012507270A5 JP2011533718A JP2011533718A JP2012507270A5 JP 2012507270 A5 JP2012507270 A5 JP 2012507270A5 JP 2011533718 A JP2011533718 A JP 2011533718A JP 2011533718 A JP2011533718 A JP 2011533718A JP 2012507270 A5 JP2012507270 A5 JP 2012507270A5
- Authority
- JP
- Japan
- Prior art keywords
- rad35
- bioreactor
- cells
- perfusion system
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 7
- 230000010412 perfusion Effects 0.000 claims 7
- 239000002245 particle Substances 0.000 claims 6
- 241000700605 Viruses Species 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 2
- 241000701124 Human adenovirus 35 Species 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002458 infectious effect Effects 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 241000701161 unidentified adenovirus Species 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19812208P | 2008-11-03 | 2008-11-03 | |
| US61/198,122 | 2008-11-03 | ||
| EP08168181.9 | 2008-11-03 | ||
| EP08168181 | 2008-11-03 | ||
| PCT/EP2009/064265 WO2010060719A1 (en) | 2008-11-03 | 2009-10-29 | Method for the production of adenoviral vectors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012507270A JP2012507270A (ja) | 2012-03-29 |
| JP2012507270A5 true JP2012507270A5 (cg-RX-API-DMAC7.html) | 2012-12-13 |
| JP5770633B2 JP5770633B2 (ja) | 2015-08-26 |
Family
ID=40344776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011533718A Expired - Fee Related JP5770633B2 (ja) | 2008-11-03 | 2009-10-29 | アデノウイルスベクターの産生方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10041049B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2350268B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5770633B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101504392B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102203242B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009319254B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0921651A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2742474C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2350268T3 (cg-RX-API-DMAC7.html) |
| EA (1) | EA019928B1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2532015T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2011004292A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ593235A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2350268T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010060719A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2350268T3 (en) | 2008-11-03 | 2015-03-23 | Crucell Holland Bv | PROCEDURE FOR PRODUCING ADENOVIRUS VECTORS |
| CN102791852B (zh) * | 2009-10-15 | 2014-05-07 | 克鲁塞尔荷兰公司 | 纯化腺病毒颗粒的方法 |
| KR101805938B1 (ko) | 2009-10-15 | 2018-01-10 | 얀센 백신스 앤드 프리벤션 비.브이. | 고밀도 세포 배양액에서 아데노바이러스의 정제 방법 |
| KR101820980B1 (ko) * | 2010-02-15 | 2018-01-22 | 얀센 백신스 앤드 프리벤션 비.브이. | Ad 26 아데노바이러스 벡터를 제조하는 방법 |
| WO2012038367A1 (en) | 2010-09-20 | 2012-03-29 | Crucell Holland B.V. | Therapeutic vaccination against active tuberculosis |
| US9168292B2 (en) | 2010-09-27 | 2015-10-27 | Crucell Holland B.V. | Heterologous prime boost vaccination regimen against malaria |
| EA023614B1 (ru) | 2011-02-10 | 2016-06-30 | Круселл Холланд Б.В. | Пневматическая безмембранная система разделения клеток с переменным давлением |
| US20130122038A1 (en) | 2011-11-14 | 2013-05-16 | The United States Of America As Represented By The Secretary Of The Department | Heterologous prime-boost immunization using measles virus-based vaccines |
| US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
| KR102044051B1 (ko) | 2012-03-12 | 2019-11-12 | 얀센 백신스 앤드 프리벤션 비.브이. | 터미널 말단이 변경된 재조합 아데노바이러스의 배치 |
| US9125870B2 (en) | 2012-03-22 | 2015-09-08 | Crucell Holland B.V. | Vaccine against RSV |
| JP5805908B2 (ja) | 2012-03-22 | 2015-11-10 | クルセル ホランド ベー ヴェー | Rsvに対するワクチン |
| AU2014259474B2 (en) | 2013-04-25 | 2018-09-13 | Janssen Vaccines & Prevention B.V. | Stabilized soluble prefusion RSV F polypeptides |
| EP3010931B1 (en) | 2013-06-17 | 2018-06-13 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion rsv f polypeptides |
| CN105473712B (zh) * | 2013-08-30 | 2022-05-27 | 葛兰素史密丝克莱恩生物有限公司 | 在细胞培养物中大规模生产病毒 |
| CN106232800B (zh) | 2014-03-25 | 2020-07-03 | 泰尔茂比司特公司 | 介质的被动替代 |
| RS58080B1 (sr) | 2014-11-04 | 2019-02-28 | Janssen Vaccines & Prevention Bv | Terapeutske vakcine protiv hpv16 |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| CA2991540A1 (en) | 2015-07-07 | 2017-01-12 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion respiratory syncytial sirus polypeptides |
| AU2016289492B2 (en) | 2015-07-07 | 2022-08-11 | Janssen Vaccines & Prevention B.V. | Vaccine against RSV |
| US9663766B2 (en) | 2015-07-24 | 2017-05-30 | Bio-Rad Laboratories, Inc. | Methods for purifying adenovirus vectors |
| HK1252967A1 (zh) | 2015-08-20 | 2019-06-06 | Janssen Vaccines & Prevention B.V. | 治疗性hpv18疫苗 |
| PT3439672T (pt) | 2016-04-05 | 2021-02-24 | Janssen Vaccines & Prevention Bv | Proteína f do rsv pré-fusão solúvel e estabilizada para uso na profilaxia de infeção por rsv |
| WO2017174564A1 (en) | 2016-04-05 | 2017-10-12 | Janssen Vaccines & Prevention B.V. | Vaccine against rsv |
| WO2017180724A1 (en) * | 2016-04-12 | 2017-10-19 | Artemis Biosystems, Inc. | Perfusion filtration systems |
| BR112018072372A2 (pt) | 2016-05-02 | 2019-02-19 | Janssen Vaccines & Prevention B.V. | combinações de vacina terapêutica contra o hpv |
| WO2017205667A1 (en) | 2016-05-25 | 2017-11-30 | Terumo Bct, Inc. | Cell expansion |
| WO2017207480A1 (en) | 2016-05-30 | 2017-12-07 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US10744196B2 (en) | 2016-07-14 | 2020-08-18 | Janssen Vaccines & Prevention B.V. | HPV vaccines |
| JP7393945B2 (ja) | 2017-03-31 | 2023-12-07 | テルモ ビーシーティー、インコーポレーテッド | 細胞増殖 |
| EP3624844A1 (en) | 2017-05-17 | 2020-03-25 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against rsv infection |
| WO2019053109A1 (en) | 2017-09-15 | 2019-03-21 | Janssen Vaccines & Prevention B.V. | METHOD FOR SAFE INDUCTION OF IMMUNITY AGAINST RSV |
| US11142551B2 (en) | 2017-10-31 | 2021-10-12 | Janssen Vaccines & Prevention B.V. | Adenovirus and uses thereof |
| EP3704256A1 (en) | 2017-10-31 | 2020-09-09 | Janssen Vaccines & Prevention B.V. | Adenovirus vectors and uses thereof |
| CN111372943B (zh) | 2017-10-31 | 2023-12-05 | 扬森疫苗与预防公司 | 腺病毒及其用途 |
| CA3079210A1 (en) | 2017-10-31 | 2019-05-09 | Janssen Vaccines & Prevention B.V. | Adenovirus and uses thereof |
| KR20250111232A (ko) | 2017-12-11 | 2025-07-22 | 암젠 인크 | 이중특이적 항체 생성물의 연속 제조 공정 |
| CN110317832B (zh) | 2018-03-28 | 2022-07-05 | 西比曼生物科技(香港)有限公司 | Gmp级规模化制备重组慢病毒载体的纯化制剂的方法 |
| CN110317791A (zh) | 2018-03-29 | 2019-10-11 | 西比曼生物科技(香港)有限公司 | Gmp级无血清悬浮细胞大规模生产慢病毒的方法 |
| EP3784276A4 (en) | 2018-04-24 | 2022-03-16 | Merck Sharp & Dohme Corp. | SCALABLE CHROMATOGRAPHY PROCEDURE FOR PURIFICATION OF HUMAN CYTOMEGALOVIRUS |
| PH12021550974A1 (en) | 2018-11-13 | 2022-05-02 | Janssen Vaccines & Prevention Bv | Stablized pre-fusion rsv f proteins |
| CA3144960A1 (en) * | 2019-07-01 | 2021-01-07 | Ology Bioservices, Inc. | Method for cultivation of adherent cells in a multiparallel bioreactor |
| JP2023512519A (ja) | 2020-01-31 | 2023-03-27 | ベス イスラエル ディーコネス メディカル センター インコーポレイテッド | コロナウイルス感染症を予防および処置するための組成物および方法-sars-cov-2ワクチン |
| GB202013940D0 (en) | 2020-09-04 | 2020-10-21 | Synpromics Ltd | Regulatory nucleic acid sequences |
| JP2023545731A (ja) | 2020-10-07 | 2023-10-31 | アスクレピオス バイオファーマシューティカル, インコーポレイテッド | 肢帯型2i(lgmd2i)を含むジストログリカノパチー障害を処置するためのフクチン関連タンパク質(fkrp)の治療的アデノ随伴ウイルス送達 |
| EP4314019A2 (en) | 2021-04-01 | 2024-02-07 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion piv3 f proteins |
| WO2023020939A1 (en) | 2021-08-17 | 2023-02-23 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| WO2023111725A1 (en) | 2021-12-14 | 2023-06-22 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| EP4448802A1 (en) | 2021-12-16 | 2024-10-23 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion hmpv fusion proteins |
| EP4590689A1 (en) | 2022-09-23 | 2025-07-30 | Janssen Vaccines & Prevention B.V. | Stabilized trimeric class i fusion proteins |
| EP4590690A1 (en) | 2022-09-23 | 2025-07-30 | Janssen Vaccines & Prevention B.V. | Pre-fusion human piv1 f proteins |
| AU2023355822A1 (en) | 2022-10-06 | 2025-04-17 | Msd International Business Gmbh | Stabilized pre-fusion piv3 f proteins |
Family Cites Families (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04241381A (ja) | 1991-01-16 | 1992-08-28 | Brother Ind Ltd | 電子学習機 |
| FR2705686B1 (fr) | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
| US5851806A (en) | 1994-06-10 | 1998-12-22 | Genvec, Inc. | Complementary adenoviral systems and cell lines |
| CA2192442C (en) | 1994-06-10 | 2007-09-25 | Imre Kovesdi | Complementary adenoviral vector systems and cell lines |
| US5559099A (en) | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
| US5846782A (en) | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| US5965541A (en) | 1995-11-28 | 1999-10-12 | Genvec, Inc. | Vectors and methods for gene transfer to cells |
| US5770442A (en) | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
| US5837520A (en) | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| EP1445322B2 (en) | 1995-06-15 | 2012-06-06 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
| CA2230655C (en) | 1995-08-30 | 2008-06-17 | Genzyme Corporation | Chromatographic purification of adenovirus and aav |
| US5837511A (en) | 1995-10-02 | 1998-11-17 | Cornell Research Foundation, Inc. | Non-group C adenoviral vectors |
| CA2177085C (en) | 1996-04-26 | 2007-08-14 | National Research Council Of Canada | Adenovirus e1-complementing cell lines |
| JP2000514290A (ja) | 1996-07-01 | 2000-10-31 | ローヌ―プーラン・ロレ・エス・アー | 組換えアデノウイルスの製造方法 |
| FR2751343B1 (fr) | 1996-07-16 | 1998-12-18 | Transgene Sa | Procede de conservation de virus recombinants infectieux, suspension aqueuse virale et utilisation comme medicament |
| US7732129B1 (en) | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
| KR100503701B1 (ko) | 1996-11-20 | 2005-07-26 | 인트로겐 테라페티스, 인코퍼레이티드 | 아데노바이러스 벡터를 생산하고 정제하는 개선된 방법 |
| US6261823B1 (en) | 1996-12-13 | 2001-07-17 | Schering Corporation | Methods for purifying viruses |
| WO1998039411A1 (en) | 1997-03-04 | 1998-09-11 | Baxter International Inc. | Adenovirus e1-complementing cell lines |
| US6020191A (en) | 1997-04-14 | 2000-02-01 | Genzyme Corporation | Adenoviral vectors capable of facilitating increased persistence of transgene expression |
| US6210683B1 (en) | 1997-09-05 | 2001-04-03 | Merck & Co., Inc. | Stabilizers containing recombinant human serum albumin for live virus vaccines |
| WO1999041416A2 (en) | 1998-02-17 | 1999-08-19 | Schering Corporation | Compositions comprising viruses and methods for concentrating virus preparations |
| US5981225A (en) | 1998-04-16 | 1999-11-09 | Baylor College Of Medicine | Gene transfer vector, recombinant adenovirus particles containing the same, method for producing the same and method of use of the same |
| EA200001096A1 (ru) | 1998-04-22 | 2001-04-23 | Джинвек, Инк. | Способ обогащения раствора аденовируса, способ точного подсчета числа аденовирусных частиц в образце раствора (варианты) и способ очистки аденовируса из клеток, инфицированных аденовирусом |
| US6113913A (en) | 1998-06-26 | 2000-09-05 | Genvec, Inc. | Recombinant adenovirus |
| US20040043489A1 (en) | 1998-07-08 | 2004-03-04 | Menzo Havenga | Gene delivery vectors provided with a tissue tropism for dendritic cells and methods of use |
| US20030017138A1 (en) | 1998-07-08 | 2003-01-23 | Menzo Havenga | Chimeric adenoviruses |
| EP1133316B1 (en) | 1998-11-16 | 2009-01-21 | Introgen Therapeutics, Inc. | Formulation of adenovirus for gene therapy |
| KR100762033B1 (ko) | 1998-12-31 | 2007-10-04 | 아방티 파르마 소시에테 아노님 | 바이러스 입자의 분리방법 |
| EP1155120B1 (fr) | 1999-02-22 | 2006-07-05 | Transgene S.A. | Procede d'obtention d'une preparation virale purifiee |
| DK1550722T3 (da) | 1999-05-17 | 2007-10-08 | Crucell Holland Bv | Rekombinant human adenovirus serotype 35 |
| US20050232900A1 (en) | 1999-05-18 | 2005-10-20 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
| US6913922B1 (en) | 1999-05-18 | 2005-07-05 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
| US6492169B1 (en) | 1999-05-18 | 2002-12-10 | Crucell Holland, B.V. | Complementing cell lines |
| DE19955558C2 (de) | 1999-11-18 | 2003-03-20 | Stefan Kochanek | Permanente Amniozyten-Zelllinie, ihre Herstellung und Verwendung zur Herstellung von Gentransfervektoren |
| US6544424B1 (en) | 1999-12-03 | 2003-04-08 | Refined Technology Company | Fluid filtration system |
| EP1263461A4 (en) | 2000-03-07 | 2009-08-12 | Merck & Co Inc | ADENOVIRUS FORMULATIONS |
| US7235233B2 (en) | 2000-09-26 | 2007-06-26 | Crucell Holland B.V. | Serotype 5 adenoviral vectors with chimeric fibers for gene delivery in skeletal muscle cells or myoblasts |
| US20020064860A1 (en) | 2000-11-29 | 2002-05-30 | Schering Corporation | Method for purifying adenoviruses |
| WO2003049763A1 (en) | 2001-12-12 | 2003-06-19 | Fh Faulding & Co Limited | Composition for the preservation of viruses |
| JP4488290B2 (ja) | 2002-01-24 | 2010-06-23 | ザ・スクリップス・リサーチ・インスティテュート | 効率的ターゲティングのためのファイバーシャフト変異 |
| US20030180936A1 (en) | 2002-03-15 | 2003-09-25 | Memarzadeh Bahram Eric | Method for the purification, production and formulation of oncolytic adenoviruses |
| WO2004001032A2 (en) | 2002-04-25 | 2003-12-31 | Crucell Holland B.V. | Stable adenoviral vectors and methods for propagation thereof |
| BR0308783A (pt) | 2002-04-25 | 2005-01-04 | Crucell Holland Bv | Vetor de adenovìrus recombinante, método para produzir um vetor de adenovìrus recombinante, composição farmacêutica, método para tratar um corpo humano, e, kit de partes |
| WO2003097797A2 (en) | 2002-05-14 | 2003-11-27 | Merck & Co., Inc. | Methods of adenovirus purification |
| AU2003288273A1 (en) | 2002-10-23 | 2004-05-13 | Crucell Holland B.V. | New settings for recombinant adenoviral-based vaccines |
| US20080153083A1 (en) | 2003-10-23 | 2008-06-26 | Crucell Holland B.V. | Settings for recombinant adenoviral-based vaccines |
| CA2507915C (en) | 2002-12-17 | 2013-07-02 | Crucell Holland B.V. | Recombinant viral-based malaria vaccines |
| JP2007525166A (ja) | 2003-03-28 | 2007-09-06 | ザ・スクリップス・リサーチ・インスティテュート | 樹状細胞に対する感染性が増大したアデノウイルス粒子と、肝細胞に対する感染性が低下した粒子 |
| HRP20130616T1 (en) | 2003-10-02 | 2013-08-31 | Crucell Holland B.V. | Packaging cells for recombinant adenovirus |
| ES2329607T3 (es) | 2004-02-23 | 2009-11-27 | Crucell Holland B.V. | Metodos de purificacion de virus. |
| EP1720972B1 (en) * | 2004-03-05 | 2014-01-08 | DSM IP Assets B.V. | Process for cell culturing by continuous perfusion and alternating tangential flow |
| US7629167B2 (en) | 2004-06-04 | 2009-12-08 | Xcellerex, Inc. | Disposable bioreactor systems and methods |
| BRPI0516048A (pt) | 2004-10-13 | 2008-08-19 | Crucell Holland B V E Beth Isr | batelada de um adenovìrus recombinante defectivo em replicação baseado em um sorotipo do subgrupo c |
| MX2007004031A (es) | 2004-10-14 | 2007-11-08 | Crucell Holland Bv | Vacunas de cebado/refuerzo contra el paludismo. |
| BRPI0518933A2 (pt) | 2004-11-16 | 2008-12-16 | Crucell Holland B V E Aeras Gl | adenovÍrus recombinante defeituoso de replicaÇço, vetor de polinucleotÍdeo recombinante, vacina multivalente da tuberculose, e, uso do antÍgeno tb10.4 de mycobacterium |
| WO2006086284A2 (en) | 2005-02-11 | 2006-08-17 | Merck & Co., Inc. | Adenovirus serotype 26 vectors, nucleic acid and viruses produced thereby |
| CA2602944C (en) | 2005-04-11 | 2015-08-11 | Crucell Holland B.V. | Virus purification using ultrafiltration |
| JP2008541730A (ja) | 2005-05-23 | 2008-11-27 | ヴァクシン インコーポレイテッド | 高力価かつ複製コンピテントアデノウイルス不含である組換えアデノウイルスベクターの迅速な作成法 |
| US20100115874A1 (en) | 2005-07-22 | 2010-05-13 | Pergo (Europe) Ab | Flooring system including a dry glue |
| JP2009512421A (ja) | 2005-08-15 | 2009-03-26 | ヴァクシン インコーポレイテッド | 非複製性ベクターワクチン投与による鳥類への免疫方法 |
| US20100143302A1 (en) | 2006-03-16 | 2010-06-10 | Crucell Holland B.V. | Recombinant Adenoviruses Based on Serotype 26 and 48, and Use Thereof |
| WO2007110409A1 (en) | 2006-03-27 | 2007-10-04 | Crucell Holland B.V. | Compositions comprising a recombinant adenovirus and an adjuvant |
| AU2007276217B2 (en) | 2006-07-18 | 2013-08-29 | Glaxosmithkline Biologicals S.A. | Vaccines for malaria |
| MX2009009342A (es) | 2007-03-02 | 2009-09-11 | Glaxosmithkline Biolog Sa | Metodo novedoso y composiciones. |
| US9109193B2 (en) | 2007-07-30 | 2015-08-18 | Ge Healthcare Bio-Sciences Corp. | Continuous perfusion bioreactor system |
| CA2705260C (en) | 2007-11-14 | 2013-08-06 | Chun-Chieh Chang | Method and devices for producing air sensitive electrode materials for lithium ion battery applications |
| WO2009117134A2 (en) | 2008-03-21 | 2009-09-24 | National Institutes Of Health | Aerosolized genetic vaccines and methods of use |
| DK2350268T3 (en) | 2008-11-03 | 2015-03-23 | Crucell Holland Bv | PROCEDURE FOR PRODUCING ADENOVIRUS VECTORS |
| MA33429B1 (fr) | 2009-07-16 | 2012-07-03 | Crucell Holland Bv | Production de poliovirus à titres élevés pour la production de vaccins |
| KR101805938B1 (ko) | 2009-10-15 | 2018-01-10 | 얀센 백신스 앤드 프리벤션 비.브이. | 고밀도 세포 배양액에서 아데노바이러스의 정제 방법 |
| KR101820980B1 (ko) | 2010-02-15 | 2018-01-22 | 얀센 백신스 앤드 프리벤션 비.브이. | Ad 26 아데노바이러스 벡터를 제조하는 방법 |
| US20120315696A1 (en) | 2010-02-15 | 2012-12-13 | Alfred Luitjens | METHOD FOR THE PRODUCTION OF Ad26 ADENOVIRAL VECTORS |
-
2009
- 2009-10-29 DK DK09744140.6T patent/DK2350268T3/en active
- 2009-10-29 ES ES09744140.6T patent/ES2532015T3/es active Active
- 2009-10-29 CA CA2742474A patent/CA2742474C/en active Active
- 2009-10-29 EA EA201170638A patent/EA019928B1/ru not_active IP Right Cessation
- 2009-10-29 AU AU2009319254A patent/AU2009319254B2/en not_active Ceased
- 2009-10-29 WO PCT/EP2009/064265 patent/WO2010060719A1/en not_active Ceased
- 2009-10-29 PL PL09744140T patent/PL2350268T3/pl unknown
- 2009-10-29 US US13/126,978 patent/US10041049B2/en active Active
- 2009-10-29 KR KR1020117010793A patent/KR101504392B1/ko not_active Expired - Fee Related
- 2009-10-29 JP JP2011533718A patent/JP5770633B2/ja not_active Expired - Fee Related
- 2009-10-29 BR BRPI0921651-0A patent/BRPI0921651A2/pt not_active Application Discontinuation
- 2009-10-29 CN CN2009801438951A patent/CN102203242B/zh not_active Expired - Fee Related
- 2009-10-29 NZ NZ593235A patent/NZ593235A/xx not_active IP Right Cessation
- 2009-10-29 EP EP09744140.6A patent/EP2350268B1/en active Active
- 2009-10-29 MX MX2011004292A patent/MX2011004292A/es active IP Right Grant
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012507270A5 (cg-RX-API-DMAC7.html) | ||
| NZ593235A (en) | Method for the production of recombinant adenovirus serotype 35 | |
| JP2014521353A5 (cg-RX-API-DMAC7.html) | ||
| JP2019516410A5 (cg-RX-API-DMAC7.html) | ||
| CN102762721B (zh) | 用于生产Ad26腺病毒载体的方法 | |
| Feuchtinger et al. | Adenovirus infection after allogeneic stem cell transplantation | |
| JP2011125348A5 (cg-RX-API-DMAC7.html) | ||
| JP2009034115A5 (cg-RX-API-DMAC7.html) | ||
| JP2004505623A5 (cg-RX-API-DMAC7.html) | ||
| WO2020076820A3 (en) | Compositions and methods for preparing viral vectors | |
| JP2004501647A5 (cg-RX-API-DMAC7.html) | ||
| JP2005512564A5 (cg-RX-API-DMAC7.html) | ||
| CN103732236A (zh) | 用于生产痘苗病毒的方法和组合物 | |
| Cornax et al. | Newcastle disease virus fusion and haemagglutinin-neuraminidase proteins contribute to its macrophage host range | |
| JP5980947B2 (ja) | 高感染価のパルボウイルスの生産方法 | |
| JP2013515473A5 (cg-RX-API-DMAC7.html) | ||
| Duffy et al. | Generation and characterization of a novel candidate gene therapy and vaccination vector based on human species D adenovirus type 56 | |
| Kimura et al. | Deletion of Viral microRNAs in the Oncogenesis of Epstein–Barr Virus-Associated Lymphoma | |
| JP2013538588A5 (cg-RX-API-DMAC7.html) | ||
| Ross et al. | Construction and characterization of adenovirus vectors | |
| JP2008508899A5 (cg-RX-API-DMAC7.html) | ||
| CN114107389A (zh) | 表达非洲猪瘟病毒b602l-b646l蛋白的重组腺病毒及构建方法 | |
| CN1552851A (zh) | Sars冠状病毒的假病毒及其制备方法和用途 | |
| CN102533657B (zh) | 一种人41型腺病毒(Ad41)包装细胞株及其应用 | |
| CN103642760B (zh) | 一种制备柯萨奇a16型病毒完整实心颗粒的方法 |