JP2012503024A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012503024A5 JP2012503024A5 JP2011528081A JP2011528081A JP2012503024A5 JP 2012503024 A5 JP2012503024 A5 JP 2012503024A5 JP 2011528081 A JP2011528081 A JP 2011528081A JP 2011528081 A JP2011528081 A JP 2011528081A JP 2012503024 A5 JP2012503024 A5 JP 2012503024A5
- Authority
- JP
- Japan
- Prior art keywords
- peptidomimetic macrocycle
- amino acid
- peptidomimetic
- independently
- macrocycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9917208P | 2008-09-22 | 2008-09-22 | |
| US61/099,172 | 2008-09-22 | ||
| PCT/US2009/057927 WO2010034028A1 (en) | 2008-09-22 | 2009-09-22 | Peptidomimetic marcrocycles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012503024A JP2012503024A (ja) | 2012-02-02 |
| JP2012503024A5 true JP2012503024A5 (enExample) | 2012-05-24 |
Family
ID=41581947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011528081A Withdrawn JP2012503024A (ja) | 2008-09-22 | 2009-09-22 | ペプチド模倣大環状分子 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120115783A1 (enExample) |
| EP (1) | EP2342214A1 (enExample) |
| JP (1) | JP2012503024A (enExample) |
| CN (1) | CN102197046A (enExample) |
| AU (1) | AU2009294871A1 (enExample) |
| BR (1) | BRPI0918833A2 (enExample) |
| CA (1) | CA2737916A1 (enExample) |
| WO (1) | WO2010034028A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2686827C (en) | 2006-12-14 | 2014-09-16 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
| CN109627287A (zh) | 2007-02-23 | 2019-04-16 | 爱勒让治疗公司 | 三唑大环系统 |
| EP2508531B1 (en) | 2007-03-28 | 2016-10-19 | President and Fellows of Harvard College | Stitched polypeptides |
| US9399666B2 (en) | 2008-09-18 | 2016-07-26 | New York University | Inhibiting interaction between the HIF-1ALPHA and p300/CBP with hydrogen bond surrogate-based helices |
| US8524653B2 (en) | 2008-09-22 | 2013-09-03 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| WO2010060112A1 (en) | 2008-11-24 | 2010-05-27 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles with improved properties |
| EP2376100B1 (en) | 2009-01-14 | 2017-10-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| CA2774973A1 (en) | 2009-09-22 | 2011-03-31 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| SI2603600T1 (sl) * | 2010-08-13 | 2019-04-30 | Aileron Therapeutics, Inc. | Peptidomimetični makrocikli |
| WO2012051405A1 (en) | 2010-10-13 | 2012-04-19 | Bristol-Myers Squibb Company | Methods for preparing macrocycles and macrocycle stabilized peptides |
| TW201806968A (zh) | 2011-10-18 | 2018-03-01 | 艾利倫治療公司 | 擬肽巨環化合物 |
| HK1205454A1 (en) | 2012-02-15 | 2015-12-18 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| KR102112373B1 (ko) * | 2012-02-15 | 2020-05-18 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방체 마크로사이클 |
| WO2014071241A1 (en) | 2012-11-01 | 2014-05-08 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
| WO2014113792A1 (en) | 2013-01-19 | 2014-07-24 | New York University | Hydrogen-bond surrogate peptides and peptidomimetics for p53 reactivation |
| WO2014138429A2 (en) * | 2013-03-06 | 2014-09-12 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and use thereof in regulating hif1alpha |
| JP2018503595A (ja) | 2014-09-24 | 2018-02-08 | エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | ペプチド模倣大環状分子およびその製剤 |
| BR112017005598A2 (pt) | 2014-09-24 | 2017-12-12 | Aileron Therapeutics Inc | macrociclos peptidomiméticos e usos dos mesmos |
| WO2016154058A1 (en) | 2015-03-20 | 2016-09-29 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| US10023613B2 (en) | 2015-09-10 | 2018-07-17 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles as modulators of MCL-1 |
| EP4023295A1 (en) * | 2020-12-29 | 2022-07-06 | IDP Discovery Pharma, S.L. | Vegf-regulating peptides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1680443B9 (en) * | 2003-11-05 | 2014-09-03 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| WO2006038208A2 (en) * | 2004-07-12 | 2006-04-13 | Medical Research Fund Of Tel Aviv Sourasky Medical Center | Agents capable of downregulating an msf-a - dependent hif-1α and use thereof in cancer treatment |
| WO2008045238A2 (en) * | 2006-10-05 | 2008-04-17 | New York Blood Center, Inc. | Stabilized therapeutic small helical antiviral peptides |
| CA2686827C (en) * | 2006-12-14 | 2014-09-16 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
| CN109627287A (zh) * | 2007-02-23 | 2019-04-16 | 爱勒让治疗公司 | 三唑大环系统 |
-
2009
- 2009-09-22 CA CA2737916A patent/CA2737916A1/en not_active Abandoned
- 2009-09-22 AU AU2009294871A patent/AU2009294871A1/en not_active Abandoned
- 2009-09-22 EP EP09743980A patent/EP2342214A1/en not_active Withdrawn
- 2009-09-22 US US13/120,376 patent/US20120115783A1/en not_active Abandoned
- 2009-09-22 WO PCT/US2009/057927 patent/WO2010034028A1/en not_active Ceased
- 2009-09-22 BR BRPI0918833A patent/BRPI0918833A2/pt not_active IP Right Cessation
- 2009-09-22 CN CN2009801422968A patent/CN102197046A/zh active Pending
- 2009-09-22 JP JP2011528081A patent/JP2012503024A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013505300A5 (enExample) | ||
| JP2012510430A5 (enExample) | ||
| JP2012515172A5 (enExample) | ||
| JP2013535514A5 (enExample) | ||
| JP2015110654A5 (enExample) | ||
| JP2012515778A5 (enExample) | ||
| JP2022095872A5 (enExample) | ||
| RU2014137107A (ru) | Пептидомиметические макроциклы | |
| JP2010505741A5 (enExample) | ||
| CN101835801B (zh) | 转铁蛋白变体和偶联物 | |
| JP2014530868A5 (enExample) | ||
| JP2019521139A5 (enExample) | ||
| JP2021100937A5 (enExample) | ||
| JP6297969B2 (ja) | 部位特異的モノｐｅｇ化エキセンジン類似体およびその調製方法 | |
| JP2015522576A5 (enExample) | ||
| JP2015508777A5 (enExample) | ||
| JP7674031B2 (ja) | 細胞透過性ペプチド | |
| JP2011511076A5 (enExample) | ||
| TW201209062A (en) | Amide based glucagon superfamily peptide prodrugs | |
| JP2018515101A5 (enExample) | ||
| JP2013520986A5 (enExample) | ||
| CN102197046A (zh) | 拟肽大环化合物 | |
| DE602005021858D1 (de) | Peptide der amylin familie, verfahren zu deren herstellung und verwendung | |
| CN1133047A (zh) | 治疗用肽衍生物 | |
| JP2017518303A5 (enExample) |