JP2012503024A5 - - Google Patents
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- Publication number
- JP2012503024A5 JP2012503024A5 JP2011528081A JP2011528081A JP2012503024A5 JP 2012503024 A5 JP2012503024 A5 JP 2012503024A5 JP 2011528081 A JP2011528081 A JP 2011528081A JP 2011528081 A JP2011528081 A JP 2011528081A JP 2012503024 A5 JP2012503024 A5 JP 2012503024A5
- Authority
- JP
- Japan
- Prior art keywords
- peptidomimetic macrocycle
- amino acid
- peptidomimetic
- independently
- macrocycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9917208P | 2008-09-22 | 2008-09-22 | |
| US61/099,172 | 2008-09-22 | ||
| PCT/US2009/057927 WO2010034028A1 (en) | 2008-09-22 | 2009-09-22 | Peptidomimetic marcrocycles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012503024A JP2012503024A (ja) | 2012-02-02 |
| JP2012503024A5 true JP2012503024A5 (enExample) | 2012-05-24 |
Family
ID=41581947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011528081A Withdrawn JP2012503024A (ja) | 2008-09-22 | 2009-09-22 | ペプチド模倣大環状分子 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120115783A1 (enExample) |
| EP (1) | EP2342214A1 (enExample) |
| JP (1) | JP2012503024A (enExample) |
| CN (1) | CN102197046A (enExample) |
| AU (1) | AU2009294871A1 (enExample) |
| BR (1) | BRPI0918833A2 (enExample) |
| CA (1) | CA2737916A1 (enExample) |
| WO (1) | WO2010034028A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0720306A2 (pt) | 2006-12-14 | 2014-02-04 | Aileron Therapeutics Inc | Sistemas de macrociclização da bis-sufidrila |
| CA2678941C (en) | 2007-02-23 | 2018-11-27 | Aileron Therapeutics, Inc. | Triazole macrocycle systems |
| JP5631201B2 (ja) | 2007-03-28 | 2014-11-26 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ステッチングされたポリペプチド |
| WO2010033879A2 (en) * | 2008-09-18 | 2010-03-25 | New York University | Inhibiting interaction between hif-1a and p300/cbp with hydrogen bond surrogate-based helices |
| CN102482336B (zh) | 2008-09-22 | 2015-05-06 | 爱勒让治疗公司 | 拟肽大环化合物 |
| CA2743177A1 (en) | 2008-11-24 | 2010-05-27 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles with improved properties |
| AU2010204648B2 (en) | 2009-01-14 | 2016-09-01 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| JP2013505300A (ja) | 2009-09-22 | 2013-02-14 | エルロン・セラピューティクス・インコーポレイテッド | ペプチド模倣大環状分子 |
| KR102104762B1 (ko) | 2010-08-13 | 2020-04-24 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티도미메틱 거대고리 |
| EP2627662B1 (en) | 2010-10-13 | 2015-09-16 | Bristol-Myers Squibb Company | Methods for preparing macrocycles and macrocycle stabilized peptides |
| EP2768518A4 (en) | 2011-10-18 | 2015-05-27 | Aileron Therapeutics Inc | PEPTIDOMIMETIC MACROCYCLES |
| CA2864120A1 (en) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| RU2642299C2 (ru) | 2012-02-15 | 2018-01-24 | Эйлерон Терапьютикс, Инк. | P53 пептидомиметические макроциклы |
| BR112015009470A2 (pt) | 2012-11-01 | 2019-12-17 | Aileron Therapeutics Inc | aminoácidos dissubstituídos e seus métodos de preparação e uso |
| US9605026B2 (en) | 2013-01-19 | 2017-03-28 | New York University | Hydrogen-bond surrogate peptides and peptidomimetics for p53 reactivation |
| WO2014138429A2 (en) * | 2013-03-06 | 2014-09-12 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and use thereof in regulating hif1alpha |
| CN107106642B (zh) | 2014-09-24 | 2021-02-26 | 艾瑞朗医疗公司 | 拟肽大环化合物及其制剂 |
| EP3197478A4 (en) | 2014-09-24 | 2018-05-30 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| JP2018516844A (ja) | 2015-03-20 | 2018-06-28 | エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | ペプチド模倣大環状分子およびその使用 |
| US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| EP3347372A4 (en) | 2015-09-10 | 2019-09-04 | Aileron Therapeutics, Inc. | PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF MCL-1 |
| EP4023295A1 (en) * | 2020-12-29 | 2022-07-06 | IDP Discovery Pharma, S.L. | Vegf-regulating peptides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005044839A2 (en) * | 2003-11-05 | 2005-05-19 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| US8143228B2 (en) * | 2004-07-12 | 2012-03-27 | Medical Research Fund Of Tel Aviv Sourasky Medical Center | Agents capable of downregulating an MSF-A dependent HIF-1α and use thereof in cancer treatment |
| US8940864B2 (en) * | 2006-10-05 | 2015-01-27 | New York Blood Center, Inc. | Stabilized therapeutic small helical antiviral peptides |
| BRPI0720306A2 (pt) * | 2006-12-14 | 2014-02-04 | Aileron Therapeutics Inc | Sistemas de macrociclização da bis-sufidrila |
| CA2678941C (en) * | 2007-02-23 | 2018-11-27 | Aileron Therapeutics, Inc. | Triazole macrocycle systems |
-
2009
- 2009-09-22 CA CA2737916A patent/CA2737916A1/en not_active Abandoned
- 2009-09-22 CN CN2009801422968A patent/CN102197046A/zh active Pending
- 2009-09-22 AU AU2009294871A patent/AU2009294871A1/en not_active Abandoned
- 2009-09-22 EP EP09743980A patent/EP2342214A1/en not_active Withdrawn
- 2009-09-22 US US13/120,376 patent/US20120115783A1/en not_active Abandoned
- 2009-09-22 JP JP2011528081A patent/JP2012503024A/ja not_active Withdrawn
- 2009-09-22 WO PCT/US2009/057927 patent/WO2010034028A1/en not_active Ceased
- 2009-09-22 BR BRPI0918833A patent/BRPI0918833A2/pt not_active IP Right Cessation
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