JP2016511751A5 - - Google Patents
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- Publication number
- JP2016511751A5 JP2016511751A5 JP2015555353A JP2015555353A JP2016511751A5 JP 2016511751 A5 JP2016511751 A5 JP 2016511751A5 JP 2015555353 A JP2015555353 A JP 2015555353A JP 2015555353 A JP2015555353 A JP 2015555353A JP 2016511751 A5 JP2016511751 A5 JP 2016511751A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- follistatin
- protein
- seq
- recombinant follistatin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361756996P | 2013-01-25 | 2013-01-25 | |
| US61/756,996 | 2013-01-25 | ||
| US201361915733P | 2013-12-13 | 2013-12-13 | |
| US61/915,733 | 2013-12-13 | ||
| PCT/US2014/012996 WO2014116981A1 (en) | 2013-01-25 | 2014-01-24 | Follistatin in treating duchenne muscular dystrophy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018203613A Division JP2019059730A (ja) | 2013-01-25 | 2018-10-30 | デュシェンヌ筋ジストロフィーの治療におけるフォリスタチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016511751A JP2016511751A (ja) | 2016-04-21 |
| JP2016511751A5 true JP2016511751A5 (enExample) | 2017-02-23 |
| JP6475639B2 JP6475639B2 (ja) | 2019-02-27 |
Family
ID=50159515
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015555353A Expired - Fee Related JP6475639B2 (ja) | 2013-01-25 | 2014-01-24 | デュシェンヌ筋ジストロフィーの治療におけるフォリスタチン |
| JP2018203613A Pending JP2019059730A (ja) | 2013-01-25 | 2018-10-30 | デュシェンヌ筋ジストロフィーの治療におけるフォリスタチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018203613A Pending JP2019059730A (ja) | 2013-01-25 | 2018-10-30 | デュシェンヌ筋ジストロフィーの治療におけるフォリスタチン |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9957309B2 (enExample) |
| EP (1) | EP2948161B1 (enExample) |
| JP (2) | JP6475639B2 (enExample) |
| KR (1) | KR102253597B1 (enExample) |
| CN (1) | CN104902915B (enExample) |
| AU (2) | AU2014209178B2 (enExample) |
| CA (1) | CA2898121A1 (enExample) |
| EA (1) | EA201590719A1 (enExample) |
| ES (1) | ES2715710T3 (enExample) |
| IL (1) | IL240024B (enExample) |
| MX (1) | MX362105B (enExample) |
| WO (1) | WO2014116981A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
| TW201627320A (zh) | 2007-02-02 | 2016-08-01 | 艾瑟勒朗法瑪公司 | 衍生自ＡｃｔＲＩＩＢ的變體與其用途 |
| EP2315602A4 (en) | 2008-06-26 | 2011-11-02 | Acceleron Pharma Inc | METHOD OF DOSING AN ACTRIIB ANTAGONIST AND MONITORING TREATED PATIENTS |
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| CA2898121A1 (en) * | 2013-01-25 | 2014-07-31 | Shire Human Genetic Therapies, Inc. | Follistatin in treating duchenne muscular dystrophy |
| ES2786253T3 (es) | 2013-03-14 | 2020-10-09 | Immusoft Corp | Métodos para la diferenciación y transducción in vitro de células b de memoria con vectores virales pseudotipados vsv-g |
| US10010498B2 (en) * | 2014-06-04 | 2018-07-03 | Acceleron Pharma Inc. | Methods for treatment of amyotrophic lateral sclerosis with follistatin fusion proteins |
| JP6568110B2 (ja) | 2014-06-04 | 2019-08-28 | アクセルロン ファーマ， インコーポレイテッド | フォリスタチンポリペプチドによる障害の処置のための方法および組成物 |
| CA2980757A1 (en) * | 2015-03-26 | 2016-09-29 | Acceleron Pharma Inc. | Follistatin-related fusion proteins and uses thereof |
| CN109152810A (zh) * | 2016-01-06 | 2019-01-04 | 康德生物医疗技术公司 | 用于预防和治疗杜氏肌肉萎缩症的方法和组合物 |
| BR112018067747A2 (pt) * | 2016-03-04 | 2019-01-08 | Shire Human Genetic Therapies | proteínas de fusão recombinantes de folistatina-fc e uso no tratamento da distrofia muscular de duchenne |
| AU2018266893A1 (en) * | 2017-05-12 | 2019-12-05 | Takeda Pharmaceutical Company Limited | Recombinant follistatin-Fc fusion proteins and use in treating Duchenne muscular dystrophy |
| KR101822633B1 (ko) * | 2017-08-22 | 2018-01-26 | (주)진셀팜 | 폴리스타틴 유래 생리활성 펩타이드, 및 이의 용도 |
| WO2019046903A1 (en) * | 2017-09-08 | 2019-03-14 | Baker Heart and Diabetes Institute | THERAPEUTIC METHOD FOR INCREASING MUSCLE MASS IN A SUBJECT |
| CA3093716A1 (en) * | 2018-03-16 | 2019-09-19 | Immusoft Corporation | B cells genetically engineered to secrete follistatin and methods of using the same to treat follistatin-related diseases, conditions, disorders and to enhance muscle growth and strength |
| WO2019191204A1 (en) * | 2018-03-28 | 2019-10-03 | Acceleron Pharma Inc. | Follistatin polypeptides for the treatment of muscle contracture |
| CA3094859A1 (en) * | 2020-10-01 | 2022-04-01 | Entos Pharmaceuticals Inc. | Proteolipid vesicles formulated with fusion associated small transmembrane proteins |
| KR102361657B1 (ko) | 2021-04-26 | 2022-02-14 | 주식회사 케이에스비튜젠 | 14-디옥시-11,12-디디히드로안드로그라폴라이드 석시네이트를 유효성분으로 함유하는 듀센형 근이영양증을 포함한 유전성 근육질환의 예방 또는 치료용 조성물 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| EP1355919B1 (en) | 2000-12-12 | 2010-11-24 | MedImmune, LLC | Molecules with extended half-lives, compositions and uses thereof |
| PL374966A1 (en) | 2002-02-21 | 2005-11-14 | Wyeth | Follistatin domain containing proteins |
| US7355018B2 (en) * | 2003-09-30 | 2008-04-08 | Regeneron Pharmaceuticals, Inc. | Modified IGF1 polypeptides with increased stability and potency |
| JP4688483B2 (ja) * | 2004-04-15 | 2011-05-25 | 株式会社テクノネットワーク四国 | フォリスタチン変異体ポリペプチド |
| WO2006130834A2 (en) | 2005-05-31 | 2006-12-07 | Board Of Regents, The University Of Texas System | IGGl ANTIBODIES WITH MUTATED FC PORTION FOR INCREASED BINDING TO FCRN RECEPTOR AND USES THEREOF |
| WO2008030367A2 (en) * | 2006-09-01 | 2008-03-13 | The General Hospital Corporation | Selective myostatin inhibitors |
| EP2315602A4 (en) * | 2008-06-26 | 2011-11-02 | Acceleron Pharma Inc | METHOD OF DOSING AN ACTRIIB ANTAGONIST AND MONITORING TREATED PATIENTS |
| KR20110031951A (ko) * | 2008-06-26 | 2011-03-29 | 악셀레론 파마 인코포레이티드 | 액티빈-ａｃｔｒｉｉａ의 길항물질 및 적혈구 수준을 증가시키기 위한 이들의 용도 |
| EP3202459B1 (en) | 2009-09-09 | 2021-04-14 | Acceleron Pharma Inc. | Actriib antagonists and dosing and uses thereof for treating obesity or type 2 diabetes by regulating body fat content |
| US9023890B2 (en) * | 2009-12-02 | 2015-05-05 | The Charlotte-Mecklenburg Hospital Authority | Nitrate esters and their use for the treatment of muscle and muscle related diseases |
| US8580922B2 (en) * | 2011-03-04 | 2013-11-12 | Shire Human Genetic Therapies, Inc. | Peptide linkers for polypeptide compositions and methods for using same |
| MY177331A (en) | 2012-06-15 | 2020-09-12 | Pfizer | Improved antagonist antibodies against gdf-8 and uses therefor |
| RS58801B1 (sr) | 2012-09-13 | 2019-07-31 | Bristol Myers Squibb Co | Skafold domenski proteini na bazi fibronektina koji se vezuju za miostatin |
| CA2898121A1 (en) * | 2013-01-25 | 2014-07-31 | Shire Human Genetic Therapies, Inc. | Follistatin in treating duchenne muscular dystrophy |
| WO2014187807A1 (en) | 2013-05-21 | 2014-11-27 | Arcarios B.V. | Follistatin derivatives |
| JP6568110B2 (ja) | 2014-06-04 | 2019-08-28 | アクセルロン ファーマ， インコーポレイテッド | フォリスタチンポリペプチドによる障害の処置のための方法および組成物 |
| US10842886B2 (en) | 2014-10-10 | 2020-11-24 | Research Institute At Nationwide Children's Hospital | Guided injections for AAV gene transfer to muscle |
-
2014
- 2014-01-24 CA CA2898121A patent/CA2898121A1/en not_active Abandoned
- 2014-01-24 WO PCT/US2014/012996 patent/WO2014116981A1/en not_active Ceased
- 2014-01-24 KR KR1020157016986A patent/KR102253597B1/ko not_active Expired - Fee Related
- 2014-01-24 AU AU2014209178A patent/AU2014209178B2/en not_active Ceased
- 2014-01-24 US US14/762,373 patent/US9957309B2/en not_active Expired - Fee Related
- 2014-01-24 EA EA201590719A patent/EA201590719A1/ru unknown
- 2014-01-24 ES ES14706362T patent/ES2715710T3/es active Active
- 2014-01-24 CN CN201480003715.0A patent/CN104902915B/zh not_active Expired - Fee Related
- 2014-01-24 EP EP14706362.2A patent/EP2948161B1/en active Active
- 2014-01-24 MX MX2015009631A patent/MX362105B/es active IP Right Grant
- 2014-01-24 JP JP2015555353A patent/JP6475639B2/ja not_active Expired - Fee Related
-
2015
- 2015-07-20 IL IL240024A patent/IL240024B/en not_active IP Right Cessation
-
2018
- 2018-04-12 US US15/951,929 patent/US10723772B2/en not_active Expired - Fee Related
- 2018-10-30 JP JP2018203613A patent/JP2019059730A/ja active Pending
-
2019
- 2019-02-06 AU AU2019200797A patent/AU2019200797B2/en not_active Ceased
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