JP2011511090A5 - - Google Patents

Download PDF

Info

Publication number
JP2011511090A5
JP2011511090A5 JP2010546007A JP2010546007A JP2011511090A5 JP 2011511090 A5 JP2011511090 A5 JP 2011511090A5 JP 2010546007 A JP2010546007 A JP 2010546007A JP 2010546007 A JP2010546007 A JP 2010546007A JP 2011511090 A5 JP2011511090 A5 JP 2011511090A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
cells
growth factor
layer
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2010546007A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011511090A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/033275 external-priority patent/WO2009100253A1/en
Publication of JP2011511090A publication Critical patent/JP2011511090A/ja
Publication of JP2011511090A5 publication Critical patent/JP2011511090A5/ja
Ceased legal-status Critical Current

Links

JP2010546007A 2008-02-07 2009-02-05 治療用タンパク質をコードする発現ベクターの硝子体内投与による光受容体のレスキュー方法 Ceased JP2011511090A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2699008P 2008-02-07 2008-02-07
US9322808P 2008-08-29 2008-08-29
PCT/US2009/033275 WO2009100253A1 (en) 2008-02-07 2009-02-05 Rescue of photoreceptors by intravitreal administation of an expression vector encoding a therapeutic protein

Publications (2)

Publication Number Publication Date
JP2011511090A JP2011511090A (ja) 2011-04-07
JP2011511090A5 true JP2011511090A5 (enExample) 2013-03-28

Family

ID=40939054

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010546007A Ceased JP2011511090A (ja) 2008-02-07 2009-02-05 治療用タンパク質をコードする発現ベクターの硝子体内投与による光受容体のレスキュー方法

Country Status (7)

Country Link
US (2) US8242093B2 (enExample)
EP (1) EP2247258A4 (enExample)
JP (1) JP2011511090A (enExample)
CN (1) CN101980668A (enExample)
AU (1) AU2009212309B2 (enExample)
CA (1) CA2713755A1 (enExample)
WO (1) WO2009100253A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009100253A1 (en) * 2008-02-07 2009-08-13 Ceregene, Inc. Rescue of photoreceptors by intravitreal administation of an expression vector encoding a therapeutic protein
GB201103062D0 (en) * 2011-02-22 2011-04-06 Isis Innovation Method
CN103459593A (zh) * 2011-02-25 2013-12-18 独立行政法人理化学研究所 视网膜色素上皮细胞片层的生产方法
EP2872183B1 (en) * 2012-07-11 2018-09-26 The Trustees Of The University Of Pennsylvania Aav-mediated gene therapy for rpgr x-linked retinal degeneration
WO2015044704A1 (en) * 2013-09-30 2015-04-02 Sanofi Use of neuroglobin agonist for preventing or treating mitochondrial rcci and/or rcciii deficiency disease
RU2723101C2 (ru) * 2013-12-06 2020-06-08 Инсерм (Инститьют Насьонал Де Ла Санте Ет Де Ла Решерш Медикаль) Вектор, способ лечения хороидермии, способ селективной экспрессии полинуклеотида
US10293059B2 (en) * 2015-04-09 2019-05-21 Cornell University Gene therapy to prevent reactions to allergens
EP3384036B1 (en) * 2015-12-04 2021-02-24 Sorbonne Université Promoters and uses thereof
CA3025975A1 (en) * 2016-04-29 2017-11-02 Gensight Biologics Sa Optogenetic visual restoration using chrimson
PL239642B1 (pl) * 2018-08-16 2021-12-20 Pomorski Univ Medyczny W Szczecinie Kompozycja do doszklistkowego podawania białka leczniczego
WO2022086990A1 (en) * 2020-10-22 2022-04-28 Visgenx, Inc. Elovl2 constructs for human gene therapy
AU2023390868A1 (en) * 2022-12-05 2025-06-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Pigment epithelium-derived factor peptides and use for treating retinal degeneration

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932479A (en) 1988-09-26 1999-08-03 Auburn University Genetic engineering of plant chloroplasts
CA2293492A1 (en) * 1997-06-11 1998-12-17 Martin Berry Cns neuroregenerative compositions and methods of use
EP1154691A4 (en) * 1999-01-05 2004-07-07 Massachusetts Eye & Ear Infirm TARGETED ADMINISTRATION OF REGULATED RELEASE MEDICINE TO RETINA AND CHOROID THROUGH SCLEROTIC
WO2000054813A2 (en) * 1999-03-15 2000-09-21 Chiron Corporation Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
US6943153B1 (en) * 1999-03-15 2005-09-13 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
AU2001241809A1 (en) 2000-02-29 2001-09-12 Auburn University Genetic engineering of drought tolerance via a plastid genome
EP2080803B1 (en) 2000-03-01 2011-05-25 Auburn University Plastid transformation vectors for expressing proinsulin fused to the cholera toxin B-subunit in plants
US7354760B2 (en) 2001-12-26 2008-04-08 University Of Central Florida Research Foundation, Inc. Expression of protective antigens in transgenic chloroplasts
AU2003253781A1 (en) 2002-07-03 2004-01-23 University Of Central Florida Expression of human interferon in transgenic chloroplasts
WO2006101634A1 (en) 2005-02-17 2006-09-28 The Regents Of The University Of California Müller cell specific gene therapy
US20060188481A1 (en) * 2005-02-22 2006-08-24 Saitama Medical School Methods for prophylactically or therapeutically treating an animal for an ocular-related disorder
JP2008537478A (ja) 2005-02-24 2008-09-18 ザ・スクリプス・リサーチ・インステイチユート 単離骨髄球様骨髄細胞集団及びそれを用いた治療方法
AU2006309281B2 (en) 2005-05-27 2011-11-03 University Of Central Florida Chloroplasts engineered to express pharmaceutical proteins
WO2009100253A1 (en) * 2008-02-07 2009-08-13 Ceregene, Inc. Rescue of photoreceptors by intravitreal administation of an expression vector encoding a therapeutic protein

Similar Documents

Publication Publication Date Title
JP7182873B2 (ja) 多重ベクターシステム及びその使用
RU2018142768A (ru) Варианты капсидов аденоассоциированного вируса и способы их применения
HRP20211024T1 (hr) Aav vektori za gensku terapiju mrežnice i cns-a
UA130154C2 (uk) Спосіб безклітинного одержання днк-вектора з замкненими кінцями
JP2020532981A (ja) 修飾型閉端dna(cedna)
EP3387137A1 (en) TARGETING PEPTIDES FOR DIRECTING ADENO-ASSOCIATED VIRUSES (AAVs)
JP2015523379A5 (enExample)
HRP20171334T1 (hr) Virioni adeno-povezanog virusa s kapsid varijantom i postupci njihove upotrebe
RU2017121593A (ru) Векторы aav, нацеленные на центральную нервную систему
CN113301956B (zh) 控制器官功能的基因治疗方法
JP2017506521A5 (enExample)
JP2015501156A5 (enExample)
JP2023528801A5 (enExample)
Hellstrom et al. Retinal ganglion cell gene therapy and visual system repair
JP7289306B2 (ja) 網膜障害を治療するための組成物及び方法
ES2199932T3 (es) Poxvirus recombinante y vacuna estreptococica que contiene proteina m.
JP2021511030A5 (enExample)
IL308645A (en) Viral vectors comprising rdh12 coding regions and methods of treating retinal dystrophies
CN112029773B (zh) 编码bdnf的核酸及其应用
US12472270B2 (en) Methods and compositions for reprogramming Müller Glia
CN115927472A (zh) 一种抗vegf抗体体内表达系统的构建和应用
JP2022523050A5 (enExample)
CA3228666A1 (en) Compositions and methods for transgene expression
KR20210130578A (ko) 폐섬유증 치료 또는 예방을 위한 세포 치료제 조성물
JP2022512667A5 (enExample)