JP2011511090A - 治療用タンパク質をコードする発現ベクターの硝子体内投与による光受容体のレスキュー方法 - Google Patents
治療用タンパク質をコードする発現ベクターの硝子体内投与による光受容体のレスキュー方法 Download PDFInfo
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| US2699008P | 2008-02-07 | 2008-02-07 | |
| US9322808P | 2008-08-29 | 2008-08-29 | |
| PCT/US2009/033275 WO2009100253A1 (en) | 2008-02-07 | 2009-02-05 | Rescue of photoreceptors by intravitreal administation of an expression vector encoding a therapeutic protein |
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| AU2009212309B2 (en) * | 2008-02-07 | 2014-04-03 | Ceregene, Inc. | Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein |
| GB201103062D0 (en) * | 2011-02-22 | 2011-04-06 | Isis Innovation | Method |
| CN103459593A (zh) * | 2011-02-25 | 2013-12-18 | 独立行政法人理化学研究所 | 视网膜色素上皮细胞片层的生产方法 |
| CA2878171C (en) * | 2012-07-11 | 2021-04-27 | The Trustees Of The University Of Pennsylvania | Aav-mediated gene therapy for rpgr x-linked retinal degeneration |
| US20160256571A1 (en) * | 2013-09-30 | 2016-09-08 | Sanofi | Invention |
| WO2015082690A1 (en) * | 2013-12-06 | 2015-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject |
| US10293059B2 (en) * | 2015-04-09 | 2019-05-21 | Cornell University | Gene therapy to prevent reactions to allergens |
| US11390866B2 (en) * | 2015-12-04 | 2022-07-19 | Sorbonne Université | Promoters and uses thereof |
| EP3448411A1 (en) * | 2016-04-29 | 2019-03-06 | Gensight Biologics SA | Optogenetic visual restoration using chrimson |
| PL239642B1 (pl) * | 2018-08-16 | 2021-12-20 | Pomorski Univ Medyczny W Szczecinie | Kompozycja do doszklistkowego podawania białka leczniczego |
| CN116916937A (zh) * | 2020-10-22 | 2023-10-20 | 维斯基因股份有限公司 | 用于人类基因疗法的elovl2构建体 |
| WO2024123461A1 (en) * | 2022-12-05 | 2024-06-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Pigment epithelium-derived factor peptides and use for treating retinal degeneration |
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| JP2002512627A (ja) * | 1997-06-11 | 2002-04-23 | アコーダ セラピーティックス | Ｃｎｓ神経再生組成物及びその使用方法 |
| JP2002539176A (ja) * | 1999-03-15 | 2002-11-19 | カイロン コーポレイション | 眼の疾患を処置または予防するための組換え遺伝子送達ベクターの使用 |
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| US5932479A (en) | 1988-09-26 | 1999-08-03 | Auburn University | Genetic engineering of plant chloroplasts |
| JP2002534139A (ja) * | 1999-01-05 | 2002-10-15 | マサチューセッツ・アイ・アンド・イア・インファーマリー | 網膜と脈絡膜への経強膜徐放性薬剤標的送達 |
| US6943153B1 (en) * | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| CA2401855A1 (en) | 2000-02-29 | 2001-09-07 | Auburn University | Genetic engineering of drought tolerance via a plastid genome |
| CA2402066C (en) | 2000-03-01 | 2015-09-29 | Auburn University | Plastid transformation vectors for expressing human proteins in plants |
| US7354760B2 (en) | 2001-12-26 | 2008-04-08 | University Of Central Florida Research Foundation, Inc. | Expression of protective antigens in transgenic chloroplasts |
| AU2003253781A1 (en) | 2002-07-03 | 2004-01-23 | University Of Central Florida | Expression of human interferon in transgenic chloroplasts |
| US20100172871A1 (en) * | 2005-02-17 | 2010-07-08 | Flannery John G | Muller Cell Specific Gene Therapy |
| US20060188481A1 (en) * | 2005-02-22 | 2006-08-24 | Saitama Medical School | Methods for prophylactically or therapeutically treating an animal for an ocular-related disorder |
| JP2008537478A (ja) * | 2005-02-24 | 2008-09-18 | ザ・スクリプス・リサーチ・インステイチユート | 単離骨髄球様骨髄細胞集団及びそれを用いた治療方法 |
| AU2006309281B2 (en) | 2005-05-27 | 2011-11-03 | University Of Central Florida | Chloroplasts engineered to express pharmaceutical proteins |
| AU2009212309B2 (en) * | 2008-02-07 | 2014-04-03 | Ceregene, Inc. | Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein |
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| JP2002512627A (ja) * | 1997-06-11 | 2002-04-23 | アコーダ セラピーティックス | Ｃｎｓ神経再生組成物及びその使用方法 |
| JP2002539176A (ja) * | 1999-03-15 | 2002-11-19 | カイロン コーポレイション | 眼の疾患を処置または予防するための組換え遺伝子送達ベクターの使用 |
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| WO2009100253A8 (en) | 2010-08-19 |
| AU2009212309B2 (en) | 2014-04-03 |
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| US8420619B2 (en) | 2013-04-16 |
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| CA2713755A1 (en) | 2009-08-13 |
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