|
US5981481A
(en)
*
|
1974-12-06 |
1999-11-09 |
The Johns Hopkins University |
Human C3b/C4b receptor (CR1)
|
|
JPH0742235B2
(ja)
|
1985-11-08 |
1995-05-10 |
三共株式会社 |
自己免疫性疾病の予防・治療剤
|
|
DE3600368C1
(de)
|
1986-01-09 |
1987-04-02 |
Goldschmidt Ag Th |
Trennmittel fuer Polyurethanformteile
|
|
IL89790A
(en)
|
1988-04-01 |
2002-05-23 |
Johns Hopking University |
Nucleic acid sequences that encode and cells that produce cr1 protein and methods of production and purification
|
|
US6458360B1
(en)
|
1990-04-25 |
2002-10-01 |
The Johns Hopkins University |
Soluble complement regulatory molecules
|
|
CA2097825A1
(en)
|
1990-12-06 |
1992-06-07 |
Henry C. Marsh, Jr. |
Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity
|
|
DE69328098T2
(de)
|
1992-06-24 |
2000-08-24 |
Adprotech Plc, Royston |
Lösliche derivate des complement type-rezeptors (cr1)
|
|
GB9301289D0
(en)
|
1993-01-22 |
1993-03-17 |
Smithkline Beecham Plc |
Novel composition
|
|
US5679546A
(en)
|
1993-09-24 |
1997-10-21 |
Cytomed, Inc. |
Chimeric proteins which block complement activation
|
|
US5648244A
(en)
|
1993-09-27 |
1997-07-15 |
President And Fellows Of Harvard College |
Production, purification, cleavage and use of fusion peptides
|
|
WO1999044625A1
(en)
|
1998-03-03 |
1999-09-10 |
John Hopkins University |
Smallpox inhibitor of complement enzymes (spice) protein and methods of inhibiting complement activation
|
|
WO2000061752A2
(en)
|
1999-04-09 |
2000-10-19 |
Washington University |
Modified complement system regulators
|
|
JP2003527115A
(ja)
|
2000-03-13 |
2003-09-16 |
セント ビンセンツ ホスピタル |
新規のｈ因子関連タンパク質５及びその抗体
|
|
US20030086940A1
(en)
|
2001-08-10 |
2003-05-08 |
Cristina Costa |
Engineered recombinant molecule that regulates humoral and cellular effector functions of the immune system
|
|
WO2004031733A2
(en)
|
2002-10-02 |
2004-04-15 |
Catalyst Biosciences |
Methods of generating and screenign for porteases with altered specificity
|
|
AU2004216176B2
(en)
|
2003-02-21 |
2008-04-03 |
Genentech, Inc. |
Methods for preventing and treating tissue damage associated with ischemia-reperfusion injury
|
|
EP1594541A4
(en)
|
2003-02-21 |
2007-03-28 |
Rikshospitalet Radiumhospitale |
METHOD AND COMPOSITIONS FOR TREATING MECONIUM ASPIRATION SYNDROME
|
|
EP2266606B1
(en)
|
2003-05-15 |
2014-09-10 |
Genentech, Inc. |
Methods and compositions for the prevention and treatment of sepsis
|
|
WO2005014849A2
(en)
|
2003-07-03 |
2005-02-17 |
Euro-Celtique, S.A. |
Genes associated with responses to neuropathic pain
|
|
US20050214318A1
(en)
|
2003-10-23 |
2005-09-29 |
Nmk Research, Llc |
Immunogenic composition and method of developing a vaccine based on fusion protein
|
|
WO2005069726A2
(en)
*
|
2004-01-21 |
2005-08-04 |
Case Western Reserve University |
Hybrid and chimeric polypeptides that regulate activation of complement
|
|
JP2005211063A
(ja)
|
2004-01-30 |
2005-08-11 |
Junko Maekuroshima |
ブレンドノニ茶
|
|
US20050169921A1
(en)
|
2004-02-03 |
2005-08-04 |
Leonard Bell |
Method of treating hemolytic disease
|
|
US20050277158A1
(en)
|
2004-06-10 |
2005-12-15 |
Ge Chen |
Method and kit for donor specific complement-fixing antibodies crossmatch
|
|
WO2006012373A2
(en)
|
2004-07-20 |
2006-02-02 |
Critical Therapeutics, Inc. |
Combination therapies of hmgb and complement inhibitors against inflammation
|
|
US7745389B2
(en)
|
2005-02-14 |
2010-06-29 |
University Of Iowa Research Foundation |
Methods for treatment of age-related macular degeneration
|
|
JP2008540385A
(ja)
|
2005-05-06 |
2008-11-20 |
ラボラトワール セローノ ソシエテ アノニム |
疾患を治療するための免疫グロブリンドメイン含有細胞表面認識分子の使用
|
|
KR101126423B1
(ko)
|
2005-10-21 |
2012-07-11 |
카탈리스트 바이오사이언시즈, 인코포레이티드 |
보체 활성화를 억제하는 변형된 프로테아제
|
|
DK2500030T4
(en)
|
2005-11-04 |
2018-10-29 |
Genentech Inc |
Use of complement pathway inhibitors for the treatment of eye diseases
|
|
JP5250548B2
(ja)
|
2006-06-21 |
2013-07-31 |
エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント |
疾患の治療のための補体ｈ因子の標的化
|
|
DE602007011937D1
(de)
|
2006-07-03 |
2011-02-24 |
Univ Johns Hopkins |
Peptidantikörperdepletion und anwendung zur probenvorbereitung für massenspektrometrie
|
|
DK2447275T3
(en)
|
2006-07-13 |
2015-06-29 |
Univ Iowa Res Found |
Methods and reagents for the treatment of age-related macular degeneration
|
|
CA2666843C
(en)
|
2006-10-20 |
2015-06-16 |
Celldex Therapeutics, Inc. |
Treatment of age-related macular degeneration and other diseases of the eye
|
|
CN106084055A
(zh)
|
2006-11-02 |
2016-11-09 |
健泰科生物技术公司 |
人源化的抗‑d因子抗体
|
|
GB0701213D0
(en)
|
2007-01-23 |
2007-02-28 |
Univ Cardiff |
Factor H polymorphisms in the diagnosis and therapy of inflammatory diseases such as age-related macular degeneration
|
|
MX2009009200A
(es)
|
2007-03-01 |
2009-10-28 |
Advanced Vision Therapies Inc |
Tratamiento de enfermedades caracterizadas por la inflamacion.
|
|
GB2447696A
(en)
|
2007-03-23 |
2008-09-24 |
Univ Exeter |
Photonic biosensor arrays
|
|
GB2447698A
(en)
|
2007-03-23 |
2008-09-24 |
Univ Exeter |
Fabrication of photonic biosensor arrays
|
|
AU2008262048B2
(en)
|
2007-06-07 |
2013-09-26 |
Genentech, Inc. |
C3b antibodies and methods for the prevention and treatment of complement- associated disorders
|
|
WO2009022246A1
(en)
|
2007-08-10 |
2009-02-19 |
Koninklijke Philips Electronics N.V. |
Sensor array for spr-based detection.
|
|
WO2009059317A2
(en)
|
2007-11-01 |
2009-05-07 |
University Of Iowa Research Foundation |
Predicting amd with snps within or near c2, factor b, plekha1, htra1, prelp, or loc387715
|
|
CL2008003241A1
(es)
|
2007-11-02 |
2009-07-31 |
Novartis Ag |
Molecula de enlace que comprende una porcion de enlace de antigeno que se enlaza con un neoepitopo de c3b; composicion farmaceutica que la comprende; y su uso para tratar trastornos oculares
|
|
WO2009121065A2
(en)
|
2008-03-28 |
2009-10-01 |
Apellis Ag |
Modulation and repletion/enhancement of the complement system for treatment of trauma
|
|
CR20170001A
(es)
|
2008-04-28 |
2017-08-10 |
Genentech Inc |
Anticuerpos anti factor d humanizados
|
|
WO2009151634A1
(en)
|
2008-06-12 |
2009-12-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Complement inhibitory agents as therapeutics in posttraumatic and degenerative arthritis
|
|
US8476032B2
(en)
|
2008-08-27 |
2013-07-02 |
Children's Hospital & Research Center Oakland |
Complement factor H-based assays for serum bactericidal activity against Neisseria meningitidis
|
|
GB0815576D0
(en)
|
2008-08-28 |
2008-10-01 |
Lucas & Co |
Analysis of glycated proteins
|
|
US8937046B2
(en)
|
2008-09-22 |
2015-01-20 |
The Regents Of The University Of Colorado, A Body Corporate |
Modulating the alternative complement pathway
|
|
JP6223659B2
(ja)
|
2008-11-10 |
2017-11-01 |
アレクシオン ファーマシューティカルズ， インコーポレイテッド |
補体関連障害を処置するための方法および組成物
|
|
WO2010056399A1
(en)
|
2008-11-17 |
2010-05-20 |
Incode Biopharmaceutics, Inc. |
Method and composition for modulating the immune system and various inflammatory conditions comprising complement depletors
|
|
EP3150635A3
(en)
|
2009-10-16 |
2017-06-21 |
Omeros Corporation |
Methods for treating disseminated intravascular coagulation by inhibiting masp-2 dependent complement activation
|
|
CN102958535A
(zh)
|
2009-11-05 |
2013-03-06 |
亚力史剑桥公司 |
阵发性夜间血红蛋白尿、溶血性贫血和涉及血管内和血管外溶血的疾病状态的治疗
|
|
GB0922659D0
(en)
|
2009-12-24 |
2010-02-10 |
Univ Edinburgh |
Factor H
|
|
WO2011109338A1
(en)
|
2010-03-01 |
2011-09-09 |
Alexion Pharmaceuticals Inc. |
Methods and compositions for treating degos' disease
|
|
AU2011222883B2
(en)
|
2010-03-05 |
2016-05-26 |
Omeros Corporation |
Chimeric inhibitor molecules of complement activation
|
|
WO2011130844A1
(en)
|
2010-04-22 |
2011-10-27 |
Patricia Marlen Nieva |
Method and apparatus for an interferometric localized surface plasmon resonance (ilspr) sensor
|
|
MX2012013233A
(es)
|
2010-05-14 |
2013-05-20 |
Univ Colorado Regents |
Grupos que apuntan a receptor 2 de complemento (cr2) mejorados.
|
|
BR112012033119A2
(pt)
|
2010-06-22 |
2016-10-25 |
Univ Colorado Regents |
anticorpos para o fragamento c3d do componente do complemento 3.
|
|
JP6092776B2
(ja)
|
2010-09-15 |
2017-03-08 |
セルデックス セラピューティクス インコーポレイテッド |
可溶性補体受容体Ｉ型（ｓＣＲ１）を用いる慢性腎症の処置
|
|
KR20130130732A
(ko)
|
2010-11-01 |
2013-12-02 |
제넨테크, 인크. |
다유전자 스코어를 이용한 진행성 노인성 황반 변성으로의 진행 예측
|
|
WO2012095519A1
(en)
|
2011-01-13 |
2012-07-19 |
Leibniz-Institut Für Naturstoff-Forschung Und Infektionsbiologie |
Potent inhibitors of complement activation
|
|
DK2694108T3
(en)
|
2011-04-08 |
2018-08-20 |
Univ Leicester |
METHODS OF TREATING DISEASES ASSOCIATED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION
|
|
BR112014013205A2
(pt)
*
|
2011-12-01 |
2020-10-27 |
Protevobio, Inc. |
proteína de fusão, seu uso e seu método de produção, composição farmacêutica, ácido nucleico, e kit
|
|
WO2013151664A1
(en)
*
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins
|
|
EA201492055A1
(ru)
|
2012-06-08 |
2015-11-30 |
Шир Хьюман Дженетик Терапис, Инк. |
ИНГАЛЯЦИОННАЯ ДОСТАВКА мРНК В НЕЛЕГОЧНЫЕ КЛЕТКИ-МИШЕНИ
|
|
US20150366997A1
(en)
|
2012-12-07 |
2015-12-24 |
Shire Human Genetics Therapies, Inc. |
COMPOSITIONS AND METHODS FOR mRNA DELIVERY
|
|
CA2899034A1
(en)
|
2013-01-23 |
2014-07-31 |
Musc Foundation For Research Development |
Targeting constructs based on natural antibodies and uses thereof
|
|
GB201301632D0
(en)
|
2013-01-30 |
2013-03-13 |
Imp Innovations |
Complement System
|
|
PT2970974T
(pt)
|
2013-03-14 |
2017-11-29 |
Alnylam Pharmaceuticals Inc |
Composições de irna de componente do complemento c5 e métodos para a sua utilização
|
|
WO2014194213A1
(en)
|
2013-05-30 |
2014-12-04 |
University Of Iowa Research Foundation |
Specific complement proteins and efficacy of antibody therapy
|
|
EP3003372B1
(en)
|
2013-06-07 |
2019-10-09 |
Duke University |
Inhibitors of complement factor h
|
|
EP3033093A1
(en)
|
2013-08-16 |
2016-06-22 |
Alexion Pharmaceuticals, Inc. |
Treatment of graft rejection by administering a complement inhibitor to an organ prior to transplant
|
|
CN104231085B
(zh)
|
2013-09-05 |
2017-03-15 |
复旦大学附属肿瘤医院 |
靶向特异性补体系统抑制剂、其制备方法及应用
|
|
GB201318170D0
(en)
|
2013-10-14 |
2013-11-27 |
Univ Edinburgh |
Proteins with Diagnostic and Therapeutic Uses
|
|
ES3032935T3
(en)
|
2013-10-22 |
2025-07-29 |
Translate Bio Inc |
Lipid formulations for delivery of messenger rna
|
|
FR3015484A1
(fr)
*
|
2013-12-20 |
2015-06-26 |
Lab Francais Du Fractionnement |
Proteines recombinantes possedant une activite de facteur h
|
|
EP3177732A4
(en)
|
2014-08-08 |
2018-04-25 |
ModernaTX, Inc. |
Compositions and methods for the treatment of ophthalmic diseases and conditions
|
|
AU2015304079B2
(en)
|
2014-08-20 |
2021-05-13 |
Stichting Sanquin Bloedvoorziening |
Factor H potentiating antibodies and uses thereof
|
|
KR101808762B1
(ko)
|
2014-10-29 |
2017-12-14 |
차의과학대학교 산학협력단 |
C3 또는 C1r 보체를 분비하는 태반 유래 세포 및 이를 포함하는 조성물
|
|
US20210318287A1
(en)
|
2015-02-16 |
2021-10-14 |
The Regents Of The University Of Michigan |
Localized surface plasmon resonance sensor systems and methods
|
|
AU2016239949A1
(en)
|
2015-03-31 |
2017-09-07 |
Sorriso Pharmaceuticals, Inc. |
Peptide construct having a protease-cleavable linker
|
|
EP3359663A4
(en)
*
|
2015-09-24 |
2019-08-14 |
The Trustees of The University of Pennsylvania |
COMPOSITION AND METHOD FOR THE TREATMENT OF A COMPLEMENT-MEDIATED DISEASE
|
|
JP2019515027A
(ja)
|
2016-04-15 |
2019-06-06 |
レジェンクスバイオ インコーポレーテッド |
翻訳後修飾された完全ヒト抗ＶＥＧＦ Ｆａｂを用いる眼疾患の治療
|
|
GB201608046D0
(en)
*
|
2016-05-09 |
2016-06-22 |
Cambridge Entpr Ltd And Syndey Children S Hospitals Network Randwick And Westmead Incorporating The |
Treatment of complement-mediated disorders
|
|
CA3029106A1
(en)
*
|
2016-06-28 |
2018-01-04 |
Universitat Ulm |
Complement inhibitors and uses thereof
|
|
GB201709222D0
(en)
*
|
2017-06-09 |
2017-07-26 |
Univ Manchester |
C3b Inactivating Polypeptide
|
|
CA3070915C
(en)
|
2017-07-25 |
2023-08-08 |
Biocon Limited |
Peptide mapping method for sequence identification of insulin & insulin analogues
|
|
GB201800620D0
(en)
|
2018-01-15 |
2018-02-28 |
Univ Manchester |
C3b Binding Polypeptide
|
|
WO2019178280A1
(en)
|
2018-03-13 |
2019-09-19 |
Amgen Inc. |
Sequential digestion of polypeptides for mass spectrometric analysis
|
|
JP7467355B2
(ja)
|
2018-05-10 |
2024-04-15 |
コンプリメント・セラピューティクス・リミテッド |
黄斑変性症を評価するための方法
|
|
CN112118859A
(zh)
|
2018-05-16 |
2020-12-22 |
杰特有限公司 |
1型可溶性补体受体变体及其用途
|
|
MX2021006930A
(es)
|
2018-12-11 |
2021-11-17 |
Q32 Bio Inc |
Construcciones de proteínas de fusión para enfermedades asociadas al complemento.
|
|
GB201821082D0
(en)
|
2018-12-21 |
2019-02-06 |
Gyroscope Therapeutics Ltd |
Combination of complement factors i and h, and vector encoding thereof
|
|
KR20220019806A
(ko)
|
2019-06-12 |
2022-02-17 |
씨에스엘 이노베이션 피티와이 엘티디 |
가용성 보체 수용체 1형 변이체 접합체 및 이의 용도
|
|
GB202006789D0
(en)
|
2020-05-07 |
2020-06-24 |
Univ Manchester |
Detection of complement proteins
|
|
GB202007353D0
(en)
|
2020-05-18 |
2020-07-01 |
Shaw Andrew |
Viral infection characterization
|
|
US20210373009A1
(en)
|
2020-05-28 |
2021-12-02 |
University Of North Texas |
Plasmonic meta-surface based molecular sensors and methods for making and using them
|
|
KR20230088630A
(ko)
|
2020-10-16 |
2023-06-20 |
자이로스코프 테라퓨틱스 리미티드 |
항-vegf 엔티티 및 음성 보체 조절인자를 코딩하는 핵산 및 연령-관련 황반 변성의 치료를 위한 그의 용도
|