JP2012247438A5 - - Google Patents
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- Publication number
- JP2012247438A5 JP2012247438A5 JP2012198693A JP2012198693A JP2012247438A5 JP 2012247438 A5 JP2012247438 A5 JP 2012247438A5 JP 2012198693 A JP2012198693 A JP 2012198693A JP 2012198693 A JP2012198693 A JP 2012198693A JP 2012247438 A5 JP2012247438 A5 JP 2012247438A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- cancer
- leukemia
- igfbp2
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81800406P | 2006-06-30 | 2006-06-30 | |
| US60/818,004 | 2006-06-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Division JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012247438A JP2012247438A (ja) | 2012-12-13 |
| JP2012247438A5 true JP2012247438A5 (https=) | 2013-03-28 |
| JP5816147B2 JP5816147B2 (ja) | 2015-11-18 |
Family
ID=38783580
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Active JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
| JP2012198693A Active JP5816147B2 (ja) | 2006-06-30 | 2012-09-10 | Igfbp2インヒビター |
| JP2013024276A Pending JP2013127473A (ja) | 2006-06-30 | 2013-02-12 | Igfbp2インヒビター |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518353A Active JP5399900B2 (ja) | 2006-06-30 | 2007-06-29 | Igfbp2インヒビター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013024276A Pending JP2013127473A (ja) | 2006-06-30 | 2013-02-12 | Igfbp2インヒビター |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20080112888A1 (https=) |
| EP (2) | EP2032989B2 (https=) |
| JP (3) | JP5399900B2 (https=) |
| AT (1) | ATE537450T1 (https=) |
| CA (1) | CA2655997A1 (https=) |
| ES (1) | ES2427924T3 (https=) |
| WO (1) | WO2008005469A2 (https=) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7217796B2 (en) * | 2002-05-24 | 2007-05-15 | Schering Corporation | Neutralizing human anti-IGFR antibody |
| PE20050928A1 (es) * | 2003-11-21 | 2005-11-08 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti-igfr1 |
| EP2283831A3 (en) * | 2004-12-03 | 2013-10-23 | Merck Sharp & Dohme Corp. | Biomakers for pre-selection of patients for anti-IGF1R therapy |
| ES2364495T3 (es) | 2005-02-03 | 2011-09-05 | The General Hospital Corporation | Método para tratar cáncer resistente a gefitinib. |
| WO2006113483A2 (en) * | 2005-04-15 | 2006-10-26 | Schering Corporation | Methods and compositions for treating or preventing cancer |
| JP2009514870A (ja) | 2005-11-04 | 2009-04-09 | ワイス | mTORインヒビター、ハーセプチン、および/またはHKI−272の抗悪性腫瘍性組み合わせ |
| US20080112888A1 (en) † | 2006-06-30 | 2008-05-15 | Schering Corporation | Igfbp2 biomarker |
| JP2010508277A (ja) * | 2006-11-01 | 2010-03-18 | ジョージ メイソン インテレクチュアル プロパティーズ,インコーポレイテッド オブ フェアファックス,バージニア | 癌を検出および抑制するための方法 |
| PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| MX2010006854A (es) * | 2007-12-18 | 2010-09-09 | Schering Corp | Biomarcadores para sensibilidad a terapia anti-receptor-1 del factor de crecimiento tipo insulina. |
| CA2718918A1 (en) * | 2008-03-25 | 2009-11-26 | Schering Corporation | Methods for treating or preventing colorectal cancer |
| BRPI0910482A2 (pt) * | 2008-04-29 | 2019-09-24 | Abbott Lab | imunoglobinas de domínio variável duplo e usos das mesmas |
| PE20100092A1 (es) * | 2008-06-03 | 2010-03-12 | Abbott Lab | Inmunoglobulina con dominio variable dual y usos de la misma |
| BRPI0913366A8 (pt) * | 2008-06-03 | 2017-07-11 | Abbott Lab | Imunoglobulinas de domínio variável duplo e seus usos |
| ES2692769T3 (es) | 2008-06-17 | 2018-12-05 | Wyeth Llc | Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina |
| WO2009154645A1 (en) * | 2008-06-20 | 2009-12-23 | Smithkline Beecham Corporation | Methods for the treatment of central nervous system tumors |
| NZ603698A (en) * | 2008-07-08 | 2014-03-28 | Abbvie Inc | Prostaglandin e2 dual variable domain immunoglobulins and uses thereof |
| CN105147713A (zh) | 2008-08-04 | 2015-12-16 | 惠氏有限责任公司 | 4-苯胺基-3-氰基喹啉和卡培他滨的抗肿瘤组合 |
| NZ592151A (en) | 2008-12-12 | 2012-10-26 | Boehringer Ingelheim Int | Anti-igf antibodies |
| CA2756870A1 (en) | 2009-03-31 | 2010-10-07 | Arqule, Inc. | Substituted indolo-pyridinone compounds |
| SG174382A1 (en) | 2009-04-06 | 2011-11-28 | Wyeth Llc | Treatment regimen utilizing neratinib for breast cancer |
| EP2424566A4 (en) * | 2009-05-01 | 2013-07-31 | Abbvie Inc | IMMUNOGLOBULINE WITH DOUBLE VARIABLE DOMAIN AND ITS USE |
| UY32808A (es) * | 2009-07-29 | 2011-02-28 | Abbott Lab | Inmunoglobulinas como dominio variable dual y usos de las mismas |
| AU2010306677B2 (en) * | 2009-10-15 | 2013-05-23 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
| UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| WO2011133636A1 (en) | 2010-04-20 | 2011-10-27 | Cedars-Sinai Medical Center | COMBINATION THERAPY WITH CD4 LYMPHOCYTE DEPLETION AND mTOR INHIBITORS |
| US8741288B2 (en) * | 2010-07-07 | 2014-06-03 | Chang Gung Medical Foundation, Linkou Branch | Protein markers for detecting liver cancer and method for identifying the markers thereof |
| PT2829881T (pt) * | 2010-07-14 | 2017-11-29 | Commw Scient Ind Res Org | Diagnóstico para cancro colo-rectal |
| US8735546B2 (en) | 2010-08-03 | 2014-05-27 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
| WO2012019031A2 (en) * | 2010-08-04 | 2012-02-09 | Ohio University | Biomarkers for growth hormone disorders |
| PE20140229A1 (es) | 2010-08-26 | 2014-03-27 | Abbvie Inc | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| US20130338033A1 (en) * | 2011-01-27 | 2013-12-19 | Virginia Commonwealth University | Diagnostic and Prognostic Markers for Metastasis |
| CA2825894C (en) | 2011-02-02 | 2021-11-30 | Amgen Inc. | Prognosis of cancer using a circulating biomarker |
| US20120214830A1 (en) | 2011-02-22 | 2012-08-23 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma |
| EP2702173A1 (en) | 2011-04-25 | 2014-03-05 | OSI Pharmaceuticals, LLC | Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment |
| UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| AR089529A1 (es) | 2011-12-30 | 2014-08-27 | Abbvie Inc | Proteinas de union especificas duales dirigidas contra il-13 y/o il-17 |
| CN102703502A (zh) * | 2012-02-27 | 2012-10-03 | 同昕生物技术(北京)有限公司 | Rta蛋白的制备方法及其在鼻咽癌检测试剂中的应用 |
| CN110133296B (zh) * | 2012-03-18 | 2022-03-25 | 镜株式会社 | 疾病样品分析装置、分析系统及分析方法 |
| US20150219669A1 (en) * | 2012-08-09 | 2015-08-06 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Diagnostic of Heart Failure |
| KR20180008921A (ko) | 2012-11-01 | 2018-01-24 | 애브비 인코포레이티드 | 항-vegf/dll4 이원 가변 도메인 면역글로불린 및 이의 용도 |
| WO2014070523A1 (en) * | 2012-11-02 | 2014-05-08 | Repros Therapeutics Inc. | Trans-clomiphene for use in cancer therapy |
| US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
| CN105324396A (zh) | 2013-03-15 | 2016-02-10 | 艾伯维公司 | 针对IL-1β和/或IL-17的双重特异性结合蛋白 |
| US11112414B2 (en) | 2013-06-06 | 2021-09-07 | Inserm (Institute National De Las Sante Et De La Recherche Medicale) | Biomarker of rehospitalization after heart failure |
| CA2937035A1 (en) | 2014-02-05 | 2015-08-13 | Cedars-Sinai Medical Center | Methods and compositions for treating cancer and infectious diseases |
| WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
| TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
| CN119792512A (zh) | 2020-10-14 | 2025-04-11 | 维里迪安治疗公司 | 用于治疗甲状腺眼病的组合物和方法 |
| TW202320850A (zh) | 2021-08-10 | 2023-06-01 | 美商維里迪恩醫療股份有限公司 | 用於治療甲狀腺眼病之組合物、劑量及方法 |
| IL326876A (en) * | 2023-09-06 | 2026-04-01 | Viridian Therapeutics Inc | Pharmaceutical preparations of anti-IGF-1R antibodies |
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| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
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| FR2834900B1 (fr) | 2002-01-18 | 2005-07-01 | Pf Medicament | Nouvelles compositions a activite anti-igf-ir et anti-egfr et leurs applications |
| DE60312639T2 (de) | 2002-01-18 | 2007-11-29 | Pierre Fabre Médicament | Antikörper gegen igf-ir und ihre verwendungen |
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| US7217796B2 (en) * | 2002-05-24 | 2007-05-15 | Schering Corporation | Neutralizing human anti-IGFR antibody |
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| TW200401638A (en) | 2002-06-20 | 2004-02-01 | Bristol Myers Squibb Co | Heterocyclic inhibitors of kinases |
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| TWI272271B (en) | 2002-07-19 | 2007-02-01 | Bristol Myers Squibb Co | Process for preparing certain pyrrolotriazine compounds |
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| AU2004212344B2 (en) | 2003-02-13 | 2009-05-07 | Pfizer Products Inc. | Uses of anti-insulin-like growth factor I receptor antibodies |
| WO2004083248A1 (en) | 2003-03-14 | 2004-09-30 | Pharmacia Corporation | Antibodies to igf-i receptor for the treatment of cancers |
| EP1613658B1 (en) | 2003-04-02 | 2012-03-14 | F. Hoffmann-La Roche AG | Antibodies against insulin-like growth factor i receptor and uses thereof |
| WO2005016970A2 (en) | 2003-05-01 | 2005-02-24 | Imclone Systems Incorporated | Fully human antibodies directed against the human insulin-like growth factor-1 receptor |
| WO2004111603A2 (en) * | 2003-05-28 | 2004-12-23 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| JP2007510434A (ja) * | 2003-11-12 | 2007-04-26 | シェーリング コーポレイション | 多重遺伝子発現のためのプラスミドシステム |
| PE20050928A1 (es) * | 2003-11-21 | 2005-11-08 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti-igfr1 |
| EP2283831A3 (en) * | 2004-12-03 | 2013-10-23 | Merck Sharp & Dohme Corp. | Biomakers for pre-selection of patients for anti-IGF1R therapy |
| WO2006113483A2 (en) * | 2005-04-15 | 2006-10-26 | Schering Corporation | Methods and compositions for treating or preventing cancer |
| KR20080019249A (ko) * | 2005-06-15 | 2008-03-03 | 쉐링 코포레이션 | 안정한 항체 제형 |
| US20080112888A1 (en) † | 2006-06-30 | 2008-05-15 | Schering Corporation | Igfbp2 biomarker |
| EP2145021A2 (en) * | 2007-05-17 | 2010-01-20 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to insulin growth factor-1 receptor modulators |
-
2007
- 2007-06-29 US US11/771,454 patent/US20080112888A1/en not_active Abandoned
- 2007-06-29 WO PCT/US2007/015423 patent/WO2008005469A2/en not_active Ceased
- 2007-06-29 EP EP07810179.7A patent/EP2032989B2/en active Active
- 2007-06-29 AT AT07810179T patent/ATE537450T1/de active
- 2007-06-29 JP JP2009518353A patent/JP5399900B2/ja active Active
- 2007-06-29 CA CA002655997A patent/CA2655997A1/en active Pending
- 2007-06-29 EP EP11162598.4A patent/EP2405270B1/en not_active Revoked
- 2007-06-29 ES ES11162598T patent/ES2427924T3/es active Active
-
2012
- 2012-09-10 JP JP2012198693A patent/JP5816147B2/ja active Active
-
2013
- 2013-02-12 JP JP2013024276A patent/JP2013127473A/ja active Pending
-
2014
- 2014-12-01 US US14/556,402 patent/US20150168424A1/en not_active Abandoned
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